832 resultados para José Juan Tablada
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Referência: Diccionario Bibliographico Brazileiro / Augusto Victorino Alves Sacramento Blake, 1899. v. 4, p. 179.
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Referência: Fundação Biblioteca Nacional.
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A bibliografia da Impressão Régia do Rio de Janeiro diz: "Terminada a publicação dos EStudos do bem comum... (1819-1820), José da Silva Lisboa planejou publicar uma coletânea dos esccritos do Padre Vieira como apêndice à obra..."
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Referência: Diccionario Bibliographico Portuguez / Innocencio Francisco da Silva, 1859. v. 3, p. 198-199.
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460 pgs.
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1 carta (mecanografiada) ; 210x290mm. Ubicación: Caja 1 - Carpeta 5
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Duración (en horas): Más de 50 horas. Destinatario: Estudiante y Docente
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1 carta (mecanografiada) ; 162x224mm. Ubicación: Caja 1 - Carpeta 9
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7 cartas (mecanografiadas) ; entre 215x286mm y 157x215mm. Ubicación: Caja 1 - Carpeta 10
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3 cartas (mecanografiadas) ; entre 220x340mm y 220x310mm. Ubicación: Caja 1 - Carpeta 11
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5 cartas (manuscritas y mecanografiadas) ; 215x160mm. Ubicación: Caja 1 - Carpeta 12
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This series will include all those people who, by means of their contributions, great and small, played a part in the consolidation of ichthyology in Argentina. The general plan of this work consists of individual factsheets containing a list of works by each author, along with reference bibliography and, whenever possible, personal pictures and additional material. The datasheets will be published primarily in chronological order, although this is subject to change by the availability of materials for successive editions. This work represents another approach for the recovery and revalorization of those who set the foundations of Argentine ichthyology while in diverse historical circumstances. I expect this to be the beginning of a major work that achieves the description of such a significant part of the history of natural sciences in Argentina.
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10 p.
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Pannexin1 (Panx1) is a plasma membrane channel permeable to relatively large molecules, such as ATP. In the central nervous system (CNS) Panx1 is found in neurons and glia and in the immune system in macrophages and T-cells. We tested the hypothesis that Panx1-mediated ATP release contributes to expression of Experimental Autoimmune Encephalomyelitis (EAE), an animal model for multiple sclerosis, using wild-type (WT) and Panx1 knockout (KO) mice. Panx1 KO mice displayed a delayed onset of clinical signs of EAE and decreased mortality compared to WT mice, but developed as severe symptoms as the surviving WT mice. Spinal cord inflammatory lesions were also reduced in Panx1 KO EAE mice during acute disease. Additionally, pharmacologic inhibition of Panx1 channels with mefloquine (MFQ) reduced severity of acute and chronic EAE when administered before or after onset of clinical signs. ATP release and YoPro uptake were significantly increased in WT mice with EAE as compared to WT non-EAE and reduced in tissues of EAE Panx1 KO mice. Interestingly, we found that the P2X7 receptor was upregulated in the chronic phase of EAE in both WT and Panx1 KO spinal cords. Such increase in receptor expression is likely to counterbalance the decrease in ATP release recorded from Panx1 KO mice and thus contribute to the development of EAE symptoms in these mice. The present study shows that a Panx1 dependent mechanism (ATP release and/or inflammasome activation) contributes to disease progression, and that inhibition of Panx1 using pharmacology or gene disruption delays and attenuates clinical signs of EAE.