904 resultados para crossing the road
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本文给出了一种针对公路自动收费系统的车辆分离检测而设计的,利用红外线发射和接收所形成的光幕,完全消除跟车现象,并能将半挂车、全挂车、单车可靠分离的红外车辆分离器。高可靠性红外车辆分离器的设计很好克服了传统红外车辆分离器环境适应性差、故障率高等缺点。本文还介绍了光幕形成的基本原理,并阐述了硬件关键点及实现方法,给出了系统硬件原理图、软件基本设计思想。
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The unique geologic, geomorphic and climatic conditions of southeast Tibet have made the region to develop the multi-style and frequently occurring geologic hazards, especially the collapses and landslides and debris flows along the section of Ranwu-Lulang in Sichuan-Tibet highway. However, most of those geologic hazards have close relationship with the loose accumulations. That is, the loose accumulations are the main carrier of most geologic hazards. Thereof, the huge-thick accumulations along the highway is regarded as the objective in the thesis to study the geologic background, hazarding model and mitigation methods comprehensively, based on the multi-disciplinary theories and former materials. First of all, in the paper, based on field engineering geologic investigations, the genetic type and the characteristics of spatiotemporal distribution of the huge-thick loose accumulations along the highway, have been analysized from the factors of regional geology and geomorphy and climate, as well as the coupling acting of those factors with inoculation and eruption of the loose accumulations geologic hazards. The huge-thick loose accumulations has complex genetic types and specific regulations of spatiotemporal distribution, closely controlled by the outer environment of the region. The accumulations are composed of earth and boulder, with disorder structure and poor sorting, specific forming environments and depositing conditions. And its physical and mechanic properties are greatly distinguished from rock and common earth inland. When Sichuan-Tibet highway was firstly constructed along the north bank of Purlung Tsangpo River, the huge-thick loose accumulations was cut into many high and steep slopes. Through the survey to the cut-slopes and systematic investigation to their failures, the combination of height and angle of the accumulations slope has been obtained. At the same time, the types of genetic structure of those cut-slopes are also analysized and concluded, as well as their failure models. It is studied in the paper that there are piaster, duality, multielement and complexity types in genetic structure, and rip-dump-repose, rip-shear-slip and weathering-flake types in failure models. Moreover, it is briefly introduced present engineering performance methods and techniques dealing with the deformation and failure of the accumulations cut-slope. It is also suggested that several new techniques of slope enforcement and the method of landslide and rockfall avoiding should be applied. The research of high and steep cut-slope along the highway has broadened the acknowledgement of the combination of cut-slope height and angle. Especially, the dissertation also has made the monographic studies about the geologic background and hazarding models and prevention methods of some classic but difficult accumulations geologic hazards. They are: (1) Research of the engineering geologic background of the 102 landslide group and key problems about the project of tunnel. The 102 landslide group is a famous accumulational one composed of glacial tills and glaciofuvial deposit. The tunnel project is a feasible and optional one which can solve the present plight of “sliding after just harnessing” in the 102 section. Based on the glacial geomorphy and its depositing character, distribution of seepage line, a few drillhole materials and some surveying data, the position of contact surface between gneiss and accumulations has been recognized, and the retreating velocities of three different time scales (short, medium and long term) have been approximately calculated, and the weathering thickness of gneiss has also been estimated in the paper. On the basis of above acknowledgement, new engineering geomechnic mode is established. Numerical analysis about the stability of the No.2 landslide is done by way of FLAC program, which supplies the conclusion that the landslide there develops periodically. Thereof, 4 projects of tunnel going through the landslide have been put forwards. Safety distance of the tunnel from clinohefron has been numerically analysized. (2) Research of the geologic setting and disaster model and hazard mitigation of sliding-sand-slope. From the geologic setting of talus cone, it is indicated that the sliding-sand-slope is the process of the re-transportation and re-deposit of sand under the gravity action and from the talus cone. It is the failure of the talus cone essentially. The layering structure of the sliding-sand-slope is discovered. The models of movement and failure of the sliding-sand-slope has been put forwards. The technique, “abamurus+grass-bush fence+degradable culture pan”, is suggested to enforcement and green the sliding-sand-slope. (3) Characteristics and hazarding model and disaster mitigation of debris flow. The sources of solid material of three oversize debris flows have been analysized. It is found that a large amount of moraine existing in the glacial valley and large landslide dam-break are the two important features for oversize debris flow to be taken place. The disaster models of oversize and common debris flows have been generalized respectively. The former model better interpret the event of the Yigong super-large landslide-dam breaking. The features of common debris flow along the highway section, scouring and silting and burying and impacting, are formulated carefully. It is suggested that check dam is a better engineering structure to prevent valley from steeply scouring by debris flow. Moreover, the function of check dam in enforcing the slope is numerically calculated by FLAC program. (4) Songzong ancient ice-dammed lake and its slope stability. The lacustrine profile in Songzong landslide, more than 88 meters thick, is carefully described and measured. The Optical Simulated Luminescence (OSL) ages in the bottom and top of the silty clay layer are 22.5±3.3 kaB.P., 16.1±1.7 kaB.P., respectively. It is indicated by the ages that the lacustrine deposits formed during the Last Glacial Maximum ranging from 25ka B.P. to 15ka B.P. The special characteristics of the lacustrine sediment and the ancient lake line in Songzong basin indicated that the lacustrine sediment is related to the blocking of the Purlung Tsangpo River by the glacier in Last Glacial Maximum from Dongqu valley. The characteristics of the lacustrine profile also indicate that the Songzong ice-dammed lake might run through the Last Glacial Maximum. Two dimensional numerical modeling and analysis are done to simulate the slope stability under the conditions of nature and earthquake by FLAC program. The factor of safety of the lacusrtine slope is 1.04, but it will take place horizontal flow under earthquake activity due to the liquefaction of the 18.33 m silt layer. The realign to prevent the road from landslide is suggested.
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In this study we examined samples of sandy sediments along the north-south transects crossing the Taklimakan Desert, the Badain Jaran Desert and the Hunshandake Sandy Land respectively. The grain size was measured via dry sieving, and the carbonate content by means of an Eijkelkamp instrument. The analyses of grain size and carbonate contents show: (1) The sand grains of the Badain Jaran Desert are coarsest and best sorted, this should be associated with the strongest usual wind among these three regions. (2) The different desert have its special wind condition in their own regions. The Badain Jaran Desert and the Taklimakan Desert both show that the wind is getting weaker from north towards south, but the Hunshandake Sandy Land have the similar wind stress from north towards south. (3) The frequency curves of the sandy sediments from the Badain Jaran Desert show a kind of distinct double peaks, presumably associated with the alternative transportations of summer and winter monsoons in the north boundaries of the summer monsoon. (4) There are great differences of the carbonate contents among these three regions, this maybe associated with the humidity, the humidity of Hunshandake Sandy Land is the best, and the one of the Taklimakan Desert would be the worst among them. Analyses of The three profiles about grain size and carbonate contents show: (1) From 8ka BP, the winter-monsoon was getting weaker, and the summer-monsoon accordingly became stronger, and about 1 ka later, the winter-monsoon was getting stronger again. (2) In the stage of the profiles, there maybe show two circles of dry and wet climate, and the climate changes in those three regions show the similar trend.
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China is experiencing a rapid development of highway ever since 1990s. By the end of 2004, the total length of the highway summed up to 33 thousand kilometers, ranking 2n in the world. After the open of highway, the accumulation of time and traffic causes the decrease of its capability. To ensure its good quality, security and operation functions, we should take some reasonable measures to maintain it periodically. At present, a big problem is that the traditional maintain measures can no longer meet the increasing requirements. Due to the characters of highway, the relationship of various maintenance data and geographic positions is even closer than any others. If we wan to improve the quality and efficiency of the maintenance work, particularly when there is need for decision-making, a great number of data that is related to geographic positions are absolutely necessary. Evidently, Geographical Information System (GIS) has incomparably advantages in dealing with these spatial information. As a result, a management system for highway maintenance work based on GIS became inevitable for the development of the maintenance of highway. The purpose of this paper is to establish a management system for highway maintenance work base on Geographical Information System (GIS), Global Positioning System (GPS) and spatial database, to manage all kinds of problems encountered in the work, and to provide support on information and methods. My study mainly includes: (1) Analysis on the current status of the maintenance and management work; overview on the history of domestic and international highway maintenance management systems; identifying the necessity and importance for establishing a management system for highway maintenance work based on GIS. (2) Based on the requirement analysis, I proposed a general design for this management system, and discussed the objective, design principles, framework, systematical structure and function design. (3) Outdoor data collection is not only a prime way to understand the current situation of the road, but also an important method for data update after the system is put into use. This paper also intends to establish a set of plan to collect data efficiently and precisely which is based on GIS and GPS technologies. (4) The maintenance management database is a supporting platform for various maintenance decision-makings. Such decisions need the support of a great amount of data, which would cause other problems, such as the diversity of the data source, difference of data formats. This paper also discussed how to deal with these problems and establish such a database. (5) To propose an approach to assess the condition of pavement, based on GIS and related maintenance models. Among all the maintenance models, the two for assessing and forecasting pavement condition are the most important and mature. This paper also analyzed these two models and introduced them in terms of the integration of models. (6) This paper took the Guangshen Highway for example, explaining how to realize a GIS for management of highway maintenance work.
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Wydział Nauk Geograficznych i Geologicznych
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The control of sound propagation and reflection has always been the goal of engineers involved in the design of acoustic systems. A recent design approach based on coordinate transformations, which is applicable to many physical systems, together with the development of a new class of engineered materials called metamaterials, has opened the road to the unconstrained control of sound. However, the ideal material parameters prescribed by this methodology are complex and challenging to obtain experimentally, even using metamaterial design approaches. Not surprisingly, experimental demonstration of devices obtained using transformation acoustics is difficult, and has been implemented only in two-dimensional configurations. Here, we demonstrate the design and experimental characterization of an almost perfect three-dimensional, broadband, and, most importantly, omnidirectional acoustic device that renders a region of space three wavelengths in diameter invisible to sound.
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Heavy particle collisions, in particular low-energy ion-atom collisions, are amenable to semiclassical JWKB phase integral analysis in the complex plane of the internuclear separation. Analytic continuation in this plane requires due attention to the Stokes phenomenon which parametrizes the physical mechanisms of curve crossing, non-crossing, the hybrid Nikitin model, rotational coupling and predissociation. Complex transition points represent adiabatic degeneracies. In the case of two or more such points, the Stokes constants may only be completely determined by resort to the so-called comparison- equation method involving, in particular, parabolic cylinder functions or Whittaker functions and their strong-coupling asymptotics. In particular, the Nikitin model is a two transition-point one-double-pole problem in each half-plane corresponding to either ingoing or outgoing waves. When the four transition points are closely clustered, new techniques are required to determine Stokes constants. However, such investigations remain incomplete, A model problem is therefore solved exactly for scattering along a one-dimensional z-axis. The energy eigenvalue is b(2)-a(2) and the potential comprises -z(2)/2 (parabolic) and -a(2) + b(2)/2z(2) (centrifugal/centripetal) components. The square of the wavenumber has in the complex z-plane, four zeros each a transition point at z = +/-a +/- ib and has a double pole at z = 0. In cases (a) and (b), a and b are real and unitarity obtains. In case (a) the reflection and transition coefficients are parametrized by exponentials when a(2) + b(2) > 1/2. In case (b) they are parametrized by trigonometrics when a(2) + b(2) <1/2 and total reflection is achievable. In case (c) a and b are complex and in general unitarity is not achieved due to loss of flux to a continuum (O'Rourke and Crothers, 1992 Proc. R. Sec. 438 1). Nevertheless, case (c) coefficients reduce to (a) or (b) under appropriate limiting conditions. Setting z = ht, with h a real constant, an attempt is made to model a two-state collision problem modelled by a pair of coupled first-order impact parameter equations and an appropriate (T) over tilde-tau relation, where (T) over tilde is the Stueckelberg variable and tau is the reduced or scaled time. The attempt fails because (T) over tilde is an odd function of tau, which is unphysical in a real collision problem. However, it is pointed out that by applying the Kummer exponential model to each half-plane (O'Rourke and Crothers 1994 J. Phys. B: At. Mel. Opt. Phys. 27 2497) the current model is in effect extended to a collision problem with four transition points and a double pole in each half-plane. Moreover, the attempt in itself is not a complete failure since it is shown that the result is a perfect diabatic inelastic collision for a traceless Hamiltonian matrix, or at least when both diagonal elements are odd and the off-diagonal elements equal and even.
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By molecular dynamics (MD) simulations we study the crystallization process in a model system whose particles interact by a spherical pair potential with a narrow and deep attractive well adjacent to a hard repulsive core. The phase diagram of the model displays a solid-fluid equilibrium, with a metastable fluid-fluid separation. Our computations are restricted to fairly small systems (from 2592 to 10368 particles) and cover long simulation times, with constant energy trajectories extending up to 76x10(6) MD steps. By progressively reducing the system temperature below the solid-fluid line, we first observe the metastable fluid-fluid separation, occurring readily and almost reversibly upon crossing the corresponding line in the phase diagram. The nucleation of the crystal phase takes place when the system is in the two-fluid metastable region. Analysis of the temperature dependence of the nucleation time allows us to estimate directly the nucleation free energy barrier. The results are compared with the predictions of classical nucleation theory. The critical nucleus is identified, and its structure is found to be predominantly fcc. Following nucleation, the solid phase grows steadily across the system, incorporating a large number of localized and extended defects. We discuss the relaxation processes taking place both during and after the crystallization stage. The relevance of our simulation for the kinetics of protein crystallization under normal experimental conditions is discussed. (C) 2002 American Institute of Physics.
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Los indicadores de sostenibilidad conforman herramientas útiles para la toma de decisiones. Las ciudades latinoamericanas, y especialmente las áreas de expansión sin planificación adecuada, enfrentan desafíos cada vez mayores para revertir problemáticas que amenazan su sostenibilidad. El presente trabajo evalúa de manera preliminar, la sostenibilidad ambiental del periurbano de Mar del Plata (Argentina) tomando como referencia algunos de los indicadores propuestos por el modelo del Banco Interamericano de Desarrollo en la Iniciativa Ciudades Emergentes y Sostenibles. Se construyó un índice sintético (Índice de Sostenibilidad Ambiental, ISA) que integra trece indicadores agrupados en ocho temas. Las situaciones más críticas (ISA: 0,45-0,558) se identifican fundamentalmente en zonas en las que se desarrollan actividades rurales y en las que se localizan asentamientos de carácter precario. El estudio realizado profundiza en el conocimiento de la dimensión ambiental de la sostenibilidad, enfatizando en el análisis de los contrastes internos del periurbano marplatense.
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Methods: In this study we determined, for the first time, the ability of microorganisms to traverse microneedle-induced holes using two different in vitro models.
Results: When employing Silescol® membranes, the numbers of Candida albicans, Pseudomonas aeruginosa and Staphylococcus epidermidis crossing the membranes were an order of magnitude lower when the membranes were punctured by microneedles rather than a 21G hypodermic needle. Apart from the movement of C. albicans across hypodermic needle-punctured membranes, where 40.2% of the microbial load on control membranes permeated the barrier over 24 h, the numbers of permeating microorganisms was less than 5% of the original microbial load on control membranes. Experiments employing excised porcine skin and radiolabelled microorganisms showed that the numbers of microorganisms penetrating skin beyond the stratum corneum were approximately an order of magnitude greater than the numbers crossing Silescol® membranes in the corresponding experiments. Approximately 103?cfu of each microorganism adhered to hypodermic needles during insertion. The numbers of microorganisms adhering to MN arrays were an order of magnitude higher in each case.
Conclusion: We have shown here that microneedle puncture resulted in significantly less microbial penetration than did hypodermic needle puncture and that no microorganisms crossed the viable epidermis in microneedle—punctured skin, in contrast to needle-punctured skin. Given the antimicrobial properties of skin, it is, therefore, likely that application of microneedle arrays to skin in an appropriate manner would not cause either local or systemic infection in normal circumstances in immune-competent patients. In supporting widespread clinical use of microneedle-based delivery systems, appropriate animal studies are now needed to conclusively demonstrate this in vivo. Safety in patients will be enhanced by aseptic or sterile manufacture and by fabricating microneedles from self-disabling materials (e.g. dissolving or biodegradable polymers) to prevent inappropriate or accidental reuse.
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Laser-driven proton and ion acceleration is an area of increasing research interest given the recent development of short pulse-high intensity lasers. Several groups have reported experiments to understand whether a laser-driven beam can be applied for radiobiological purposes and in each of these, the method to obtain dose and spectral analysis was slightly different. The difficulty with these studies is that the very large instantaneous dose rate is a challenge for commonly used dosimetry techniques, so that other more sophisticated procedures need to be explored. This paper aims to explain a method for obtaining the energetic spectrum and the dose of a laser-driven proton beam irradiating a cell dish used for radiobiology studies. The procedure includes the use of a magnet to have charge and energy separation of the laser-driven beam, Gafchromic films to have information on dose and partially on energy, and a Monte Carlo code to expand the measured data in order to obtain specific details of the proton spectrum on the cells. Two specific correction factors have to be calculated: one to take into account the variation of the dose response of the films as a function of the proton energy and the other to obtain the dose to the cell layer starting from the dose measured on the films. This method, particularly suited to irradiation delivered in a single laser shot, can be applied in any other radiobiological experiment performed with laser-driven proton beams, with the only condition that the initial proton spectrum has to be at least roughly known. The method was tested in an experiment conducted at Queen's University of Belfast using the TARANIS laser, where the mean energy of the protons crossing the cells was between 0.9 and 5 MeV, the instantaneous dose rate was estimated to be close to 10(9) Gy s(-1) and doses between 0.8 and 5 Gy were delivered to the cells in a single laser shot. The combination of the applied corrections modified the initial estimate of dose by up to 40%.
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The road to molecular logic and computation in Belfast, Northern Ireland started with chemical sensors in Colombo, Sri Lanka. This journey is mapped out with reference to design principles, such as those for luminescent PET (photoinduced electron transfer) sensing. Applications such as those for blood electrolyte diagnostics, "lab-on-a-molecule" systems, and molecular computational identification (MCID) are also met along the way.
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Research over the past decade has confirmed that epigenetic alterations act in concert with genetic lesions to deregulate gene expression in acute myeloid leukemia and myelodysplastic syndromes. In addition, we now have the capability to pharmaceutically target epigenetic modifications, and there is an urgent need forearly validation of the efficacy of the drugs. Also, an improved understanding of the functionality of epigenetic modifications may further pave the road towards an individualized therapy. Here, we provide the pros and cons of the currently most feasible methods used for characterizing the methylome in clinical samples, and give a brief introduction to novel approaches to sequencing that may revolutionize our abilities to characterize the genomes and epigenomes in acute myeloid leukemia and myelodysplastic syndrome patients.
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Objectives To compare risk of fatal injury in elderly road users (drivers, passengers, pedestrians) with that of younger age groups and to assess the contribution of elderly road users to the number of reported fatalities in the population. Design Fatality age was categorized as 21 to 29, 30 to 39, 40 to 49, 50 to 59, 60 to 69, or 70 and older, and road user was categorized as driver, passenger, or pedestrian. Estimated number of trips made by each age group was used to adjust for exposure and to measure individual risk. Setting Fatalities recorded in Britain between 1989 and 2009. Participants Population-wide fatal injury counts in Britain. Measurements Age of fatally injured drivers, passengers, and pedestrians. Estimated number of trips made per year by drivers, passengers, and pedestrians. Results Risk of fatal injury, but not fatality numbers in the population, were higher for older adult (=70) drivers than for younger age groups. Risk of fatal injury was also high for older adult passengers and pedestrians, who represented the majority of older adult fatalities. Conclusion Previous emphasis on driver impairment in older age has unduly focussed attention on elderly drivers, who represent a minority of all driver fatalities. Older adults represent a much larger proportion of passenger and pedestrian fatalities. Additional policy schemes and initiatives should be targeted at safeguarding older adult passengers and making the road environment safer for elderly pedestrians. © 2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society.
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Aim - To describe a surgical technique for autologous limbal stem cell transplantation and the outcome of a series of patients with unilateral stem cell deficiency. Methods - A report of six consecutive patients who underwent autologous limbal stem cell transplantation is presented. The primary diagnosis included alkali burn (n = 3), conjunctival intraepithelial neoplasia (CIN) (n = 1), recurrent pterygium (n = 1), and contact lens induced keratopathy (n = 1). The autologous transplanted tissue consisted of peripheral cornea, limbus, and conjunctiva obtained from the contralateral eye. Three of the above patients underwent penetrating keratoplasty in association with autolimbal transplantation. A significant modification to established techniques was the close monitoring of conjunctival epithelial migration in the immediate postoperative period. If conjunctival epithelium threatened to migrate on to the corneal surface, it was mechanically removed at the slit lamp and prevented from crossing the limbus. This was required in three patients. Results - The mean follow up was 18.8 months. The outcome was satisfactory in all cases: a stable corneal surface was restored and there was a substantial improvement in vision and symptoms. One patient had a primary failure of the corneal allograft associated with glaucoma, and 6 months later developed a retinal detachment. No complications were noted in the donor eye with the exception of one patient who developed filamentary keratitis along the edge of the donor site. Conclusion - Autologous limbal transplantation with corneal, limbal, and conjunctival carriers was found to be useful for ocular surface reconstruction, over a mid-term follow up, in patients with unilateral stem cell deficiency. Close monitoring of the migration of conjunctival epithelium in the immediate postoperative period, and preventing it from crossing the limbus, ensured that the corneal surface was re-epithelialised exclusively from epithelial cells derived from the transplanted limbal tissue. This approach should improve the success of this procedure.