995 resultados para Seguimento de exames laboratoriais


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Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

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Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

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The main objective is to create a software, using C++ language, for reading and exhibiting in a graphic an Electrocardiogram (ECG) wave. The data is recorded as a FM modulated signal and compressed using Adaptive Differential Pulse Code Modulation (ADPCM). The signal have this characteristics because it was acquired using an experimental equipment, this equipment is the result of research made by the professor who supervised this work. FM demodulation techniques in discrete time, discrete filters and digital signal processing are some of the topics that can be found in this essay. Some concepts about the human heart and about ECG waves are also briefly introduced. These concepts are necessary for understanding the final evaluation of the software performance. The development is partly made using MATLAB. Most of the functions that are used on the software are first tested and designed in MATLAB environment. In the end, an evaluation is done comparing the results that are expected with the ones that MATLAB presents and the ones that the developed software presents

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This study aims to determine surface skin doses in dogs (with suspected pulmonary metastasis) submitted to chest X-rays using the technique of thermoluminescence dosimetry. Twenty seven exams from different dogs were performed at the Faculdade de Medicina Veterinária e Zootecnia da Universidade Estadual Paulista (FMVZ-UNESP/Botucatu). The doses were evaluated using thermoluminescent dosimeters of calcium sulphate doped with dysprosium (CaSO4:Dy) produced by the Instituto de Pesquisas Energéticas e Nucleares (IPEN-CNEN). The pulmonary metastasis exams are carried out in three projections, one dorsal-ventral and two lateral-lateral. During the procedures the projection thicknesses and source-skin surface distances were registered. To simulate the dog phantom the dosimeters were positioned in a cubic simulator (30x30x30 cm) of polymethylmethacrylate (PMMA) filled with water and irradiated according to the parameters of projections with the X-ray energies ranging from 45 to 70 kV. To estimate the surface skin dose the dose-response curves were obtained for X-ray energies of 50 and 70 kV using the diagnostic X-ray beam machine of the Instruments Calibration Laboratory of IPEN for doses of 1.5, 2.0, 2.5, 3.5 and 4.0 mGy. The main difficulty of this work was the dog immobilization that is reflected in poor-quality diagnostic imaging and, consequently, demands the repetition of the exams, which contributes to the increase of the doses received by the animals being studied and the clinical staff. The doses evaluated in this type of procedure are between 0.43 and 4.22 mGy. This research has shown to be extremely important for the assessment of doses involved in veterinary diagnostic radiology procedures, and as a parameter in the individual monitoring of pet’s owners who assist the animal positioning and occupationally exposed workers of the Department of Veterinary Radiology

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Pós-graduação em Medicina Veterinária - FCAV

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Pós-graduação em Cirurgia Veterinária - FCAV

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This paper consists in the evaluation of the exposure rate to ionizing radiation to which professionals working in surgical procedures which require radiological examinations are subjected. Were initially performed real-time readings of exposure rate within four distinct operating rooms during the execution of four surgical procedures that made use of fluoroscopy equipment (including three orthopedic surgeries, one in the shoulder, one in the arm, another for deployment of metal pin in the leg region, and a fourth for vascular procedure); in these surgeries were used ionization chamber detector and an electrometer. In order to check the values achieved, was made a re-evaluation of the distribution of the rate of exposure to radiation, from the surgical procedures, now with thermoluminescent dosimeters (TLDs). For this, thirty TLDs were distributed in the operating rooms, arranged in points of interest as occupation by professionals. The TLDs were prepared for thirty consecutive days, after which they were removed and replaced with new dosimeters not exposed yet. The dosimeters were subjected to reading of the rate of exposure; this procedure was repeated for four months without interruption. The quantification of the results sought primarily to convert the rate of exposure for equivalent dose rate, both in measurements with ionization chamber as in measurements with TLDs, in order to highlight the presence of the biological effect of ionizing radiation for comparisons within scientific context. Then, the results were plotted to establish the relationship between the values of equivalent dose and the distance to the central axis of the x -ray source, confirming the inverse square law for distance. Finally, the values were associated with the maximum limit recommended by the legislation for occupationally exposed individuals. The methodology for the analysis and quantification of the data in this work aims at implementing a work plan that meets ...

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Pós-graduação em Fisiopatologia em Clínica Médica - FMB

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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As alterações que afetam as hemoglobinas estão relacionadas à síntese estrutural ou quantitativa dos aminoácidos que compõem as diferentes cadeias globínicas (α/β). Existem inúmeras causas que podem resultar nessas alterações, dentre elas as mutações. A talassemia é um dos distúrbios genéticos mais frequentes do homem e mais difundidos no mundo. Fatos históricos, como imigração e colonização populacionais de diferentes partes do mundo, contribuíram para a difusão da patologia em outras localidades, incluindo o Brasil. A forma de manifestação clínica e laboratorial da talassemia do tipo beta menor (BTT), foi objeto de estudo nesta revisão bibliográfica, pois embora seja uma patologia que não mostra claramente manifestações sintomáticas, seus aspectos clínicos e laboratoriais são muito relevantes. A importância do diagnóstico laboratorial das anemias microcíticas e hipocrômicas presentes, tanto em indivíduos portadores de deficiência de ferro como em beta talassêmicos menor, é um ponto chave quando nos referimos a esses parâmetros, pois os índices HCM e VCM apresentam-se com valores extremamente reduzidos (<24 pg e <70 fL) e a quantidade de glóbulos vermelhos muito aumentados (> 5,0 milhões/μL), na beta talassemia menor em comparação à deficiência de ferro. Portanto os valores contidos no hemograma bem como a presença da inclusão citoplasmática ponteado basófilo e morfologia das hemácias observadas em análise de extensões sanguíneas coradas, é de grande valia na suspeita da beta talassemia menor, tornando-se ponto importante na sugestão da realização de eletroforese de hemoglobina para confirmação do diagnóstico da beta talassemia menor, devido ao aumento quantitativo da Hb A2.

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During the retaining wall project in soil reinforced with geogrids and face milling system for segmental blocks is essential to determine the maximum connection resistance between the block and the geogrid. Thus, the aim of this study was to analyze the connection resistance based on ASTM D- 6638-01 between the segmental block model MW of Muros Terrae® company with the geogrids model Fortrac® M 35 / 20x20, Fortrac® M 55 / 30x20, Fortrac® M 80 / 30x20 and Fortrac® M 110 / 30x20 of HUESKER Synthetic GmbH using gravel 1 as a filling material. As a result, the resistance curves were obtained for the four models of geogrids and was described how it fracture. An additional investigation was the average gain connection resistance percentage when it is applied to geogrid a second layer instead of a single layer. The average percentage gains in the connection resistance to the geogrids model Fortrac® M 35 / 20x20, Fortrac® M 55 / 30x20, Fortrac® M 80 / 30x20 and Fortrac® M 110 / 30x20 were, respectively, 63.20 %, 63, 47%, 62.23 % and 51.34 %. Finally, we made a comparative analysis of the results of this study with those obtained by Guimarães (2006), Urashima et. al (2008) and Almeida and Toma (2011) to evaluate which combinations offered higher connection resistance

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Nowadays, the fixed partial dentures and/or dental implants is the most requested treatmentby the majority of partially edentulous patients. However, depending on the periodontal condition of the remaining teeth, as well as the bone condition of the prosthetic space, the oral rehabilitation with these treatments may be limited or even contraindicated. In such cases, the use of removable partial dentures associated to attachments becomes an important alternative for aesthetic and functional rehabilitation. Attachments are mechanical devices consisted of two parts (patrix-matrix), one placed inside another, which act as direct retainer, providing retention, support and stability to the dentures. These devices can be classified as intra or extracoronal attachments, considering their position in relation to the abutment tooth. However, regardless the type of attachment, the association between fixed and removable partial dentures should be performed respecting the biomechanical principles of both. Therefore, the purpose of this study was to review and discuss the literature about the clinical and laboratory implications of the association between fixed and removable partial dentures by means of attachments.