Severe Cutaneous Leishmaniasis in a Human Immunodeficiency Virus Patient Coinfected with Leishmania braziliensis and Its Endosymbiotic Virus.

Leishmaniaparasites cause a broad range of disease, with cutaneous afflictions being, by far, the most prevalent. Variations in disease severity and symptomatic spectrum are mostly associated to parasite species. One risk factor for the severity and emergence of leishmaniasis is immunosuppression, usually arising by coinfection of the patient with human immunodeficiency virus (HIV). Interestingly, several species ofLeishmaniahave been shown to bear an endogenous cytoplasmic dsRNA virus (LRV) of theTotiviridaefamily, and recently we correlated the presence of LRV1 withinLeishmaniaparasites to an exacerbation murine leishmaniasis and with an elevated frequency of drug treatment failures in humans. This raises the possibility of further exacerbation of leishmaniasis in the presence of both viruses, and here we report a case of cutaneous leishmaniasis caused byLeishmania braziliensisbearing LRV1 with aggressive pathogenesis in an HIV patient. LRV1 was isolated and partially sequenced from skin and nasal lesions. Genetic identity of both sequences reinforced the assumption that nasal parasites originate from primary skin lesions. Surprisingly, combined antiretroviral therapy did not impact the devolution ofLeishmaniainfection. TheLeishmaniainfection was successfully treated through administration of liposomal amphotericin B.

Read this if you plan to breathe this summer : advisory for those with asthma & breathing problems and for children, older adults, and people who work outdoors.

Mode of access: Internet.

Group psychotherapy with children : the theory and practice of play-therapy.

Mode of access: Internet.

The American vegetable practice, or, A new and improved guide to health. : Designed for the use of families. : In six parts. Part I. Concise view of the human body, with engraved and wood-cut illustrations. Part II. Glance at the old school practice of physic. Part III. Vegetable materia medica, with colored illustrations. Part IV. Compounds. Part V. Practice of medicine, based upon what are deemed correct physiological and pathological principles. Part VI. Guide for women, containing a simplified treatise on childbirth, with a description of the diseases peculiar to females and infants. /

Errata and advertisement for "New England Depot. D.L. Hale" at end of v. 2.

Parents' guide to the development of preschool children with disabilities : resources and services /

"May 1992."

Experiences with infants in the preparation of home economists. Report of a conference called by the Children's Bureau and the Office of Education, Feb. 3-5, 1955, Washington, D. C.

Mode of access: Internet.

An ecclesiastical history, ancient and modern; in which the rise, progress, and variations of church power, are considered in their connexion with the state of learning and philosophy, and the political history of Europe during that period.

Mode of access: Internet.

Contributions to midwifery, and diseases of women and children : with a report on the progress of obstetrics, and uterine and infantile pathology in 1858 /

Mode of access: Internet.

A work book in citizenship training for children ... with special reference to civics, health, safety education, morals and manners, and thrift.

Mode of access: Internet.

Medicaid and special education : coordination of services for children with disabilities is evolving : report to the Honorable Edolphus Towns, House of Representatives /

"GAO/HEHS-00-20."

The history of Scotland, related in familiar conversations, by a father to his children: interspersed with moral and instructive remarks, and observations on the most leading and interesting subjects. Designed for the perusal of youth.

Summers, Gothic Bib., p. 63.

Treasures of science, history and literature : instructive, amusing, practical, for the study and the fireside : comprising curiosities of human life ... embellished throughout with choice and appropriate gems of poetry /

"Illustrated with suitable cuts and twelve full-page engravings."

The statement of the Advisory Committee on Services for Families with Infants and Toddlers.

"September 1994."

Parent to parent : a guide for parents of children with special needs.

Description based on: 1989.