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Clarias (Clarias gariepinus) (Burshell, 1821) fingerlings were fed isonitrogenous diets (38.9% crude protein) with fermented fluted pumpkin leaves (FFPL) replacing different proportion (0,50,75,100%) of extruded soybean meal (ESM) for 8 weeks. Growth responses at the different substitution levels measured. Increasing FFPL intake resulted in better weight gains and higher specific growth rates (SGR) of 0.29, 0.36 and 0.38% per day respectively. The increase in growth from feeding diets containing 75% and 100% of the ESM replaced with FFPL were significantly higher (P<0.05) than those of other diets. Further more fish tissue protein deposition consistently increased with increasing level of FFPL concentration in their diets. Fish fed diets where whole ESM was replace 100% FFPL gave the best overall response in terms of their weight gain, food conversion ratio, protein efficiency ratio, and specific growth rate. Economic considerations indicate the replacement of ESM with FFPL, which is a cheaper ingredient in feeds for Clarias

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<p>An economic air pollution control model, which determines the least cost of reaching various air quality levels, is formulated. The model takes the form of a general, nonlinear, mathematical programming problem. Primary contaminant emission levels are the independent variables. The objective function is the cost of attaining various emission levels and is to be minimized subject to constraints that given air quality levels be attained.</p> <p>The model is applied to a simplified statement of the photochemical smog problem in Los Angeles County in 1975 with emissions specified by a two-dimensional vector, total reactive hydrocarbon, (RHC), and nitrogen oxide, (NO<sub>x</sub>), emissions. Air quality, also two-dimensional, is measured by the expected number of days per year that nitrogen dioxide, (NO<sub>2</sub>), and mid-day ozone, (O<sub>3</sub>), exceed standards in Central Los Angeles.</p> <p>The minimum cost of reaching various emission levels is found by a linear programming model. The base or "uncontrolled" emission levels are those that will exist in 1975 with the present new car control program and with the degree of stationary source control existing in 1971. Controls, basically "add-on devices", are considered here for used cars, aircraft, and existing stationary sources. It is found that with these added controls, Los Angeles County emission levels [(1300 tons/day RHC, 1000 tons /day NO<sub>x</sub>) in 1969] and [(670 tons/day RHC, 790 tons/day NO<sub>x</sub>) at the base 1975 level], can be reduced to 260 tons/day RHC (minimum RHC program) and 460 tons/day NO<sub>x</sub> (minimum NO<sub>x</sub> program).</p> <p>"Phenomenological" or statistical air quality models provide the relationship between air quality and emissions. These models estimate the relationship by using atmospheric monitoring data taken at one (yearly) emission level and by using certain simple physical assumptions, (e. g., that emissions are reduced proportionately at all points in space and time). For NO<sub>2</sub>, (concentrations assumed proportional to NO<sub>x</sub> emissions), it is found that standard violations in Central Los Angeles, (55 in 1969), can be reduced to 25, 5, and 0 days per year by controlling emissions to 800, 550, and 300 tons /day, respectively. A probabilistic model reveals that RHC control is much more effective than NO<sub>x</sub> control in reducing Central Los Angeles ozone. The 150 days per year ozone violations in 1969 can be reduced to 75, 30, 10, and 0 days per year by abating RHC emissions to 700, 450, 300, and 150 tons/day, respectively, (at the 1969 NO<sub>x</sub> emission level).</p> <p>The control cost-emission level and air quality-emission level relationships are combined in a graphical solution of the complete model to find the cost of various air quality levels. Best possible air quality levels with the controls considered here are 8 O<sub>3</sub> and 10 NO<sub>2</sub> violations per year (minimum ozone program) or 25 O<sub>3</sub> and 3 NO<sub>2</sub> violations per year (minimum NO<sub>2</sub> program) with an annualized cost of $230,000,000 (above the estimated $150,000,000 per year for the new car control program for Los Angeles County motor vehicles in 1975).</p>

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Experimental stocking density of Macrobrachium rosenbergii in larval rearing was conducted in A.G. Aqua Hatchery, Chakaria, Bangladesh to study the effect of different stocking densities on growth, survival rate and diseases stress under hatchery condition. The research work was conducted using six cemented rectangular tanks having 3m3 capacity (1.5mX2mX1m) each. Stocking density were maintained in three experimental setup as 200, 150 and 100ind/L of the T1, T2 and T3 respectively with one replicate each. The larvae were fed with Artemia nauplii, Custard, Maxima and brine shrimp flakes. Water quality was maintained by exchanging 20-30% (12ppt saline water) daily. During the study period, temperature, pH, DO, salinity, nitrite-nitrogen, ammonia and alkalinity were maintained from 28.5-31.5C, 7.5-7.8, 5.8-5.9mg/L, 12-13ppt, 0.14-0.2 mg/L, 0.22-0.3mg/L, and 140-160mg/L respectively. The growth rates of larvae at 11th stage were recorded in terms of body length 0.115, 0.136, and 0.169 mm/day whereas body weight were observed 0.000115, 0.000180, and 0.000240g/day. The survival rate of larvae were found 21.8%, 30.4% and 51.3% in treatments T1, T2 and T3 respectively. PL was obtained as 43, 45, and 51PL/L and days required of 41, 38 and 34 days in stocking density of 200, 150, and 100ind/L respectively. It was found that the minimum of 34 days was required to attain the PL (12th stage) using the stocking density of 100 individuals/L. Cannibalism, Zoothamnium, Exuvia Entrapment Disease (EED), and Bacterial Necrosis (BN) were found to be the threat to the commercial hatchery operation that might responsible for potential larval damages which can be reduced by lowering the stocking densities in larval rearing tank that also increased the survival and growth rate.

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<p>We carried out quantum mechanics (QM) studies aimed at improving the performance of hydrogen fuel cells. This led to predictions of improved materials, some of which were subsequently validated with experiments by our collaborators.</p> <p>In part I, the challenge was to find a replacement for the Pt cathode that would lead to improved performance for the Oxygen Reduction Reaction (ORR) while remaining stable under operational conditions and decreasing cost. Our design strategy was to find an alloy with composition Pt3M that would lead to surface segregation such that the top layer would be pure Pt, with the second and subsequent layers richer in M. Under operating conditions we expect the surface to have significant O and/or OH chemisorbed on the surface, and hence we searched for M that would remain segregated under these conditions. Using QM we examined surface segregation for 28 Pt<sub>3</sub>M alloys, where M is a transition metal. We found that only Pt<sub>3</sub>Os and Pt<sub>3</sub>Ir showed significant surface segregation when O and OH are chemisorbed on the catalyst surfaces. This result indicates that Pt<sub>3</sub>Os and Pt3Ir favor formation of a Pt-skin surface layer structure that would resist the acidic electrolyte corrosion during fuel cell operation environments. We chose to focus on Os because the phase diagram for Pt-Ir indicated that Pt-Ir could not form a homogeneous alloy at lower temperature. To determine the performance for ORR, we used QM to examine all intermediates, reaction pathways, and reaction barriers involved in the processes for which protons from the anode reactions react with O<sub>2</sub> to form H<sub>2</sub>O. These QM calculations used our Poisson-Boltzmann implicit solvation model include the effects of the solvent (water with dielectric constant 78 with pH 7 at 298K). We found that the rate determination step (RDS) was the O<sub>ad</sub> hydration reaction (O<sub>ad</sub> + H<sub>2</sub>O<sub>ad</sub> -&#62; OH<sub>ad</sub> + OH<sub>ad</sub>) in both cases, but that the barrier for pure Pt of 0.50 eV is reduced to 0.48 eV for Pt<sub>3</sub>Os, which at 80 degrees C would increase the rate by 218%. We collaborated with the Pu-Wei Wus group to carry out experiments, where we found that the dealloying process-treated Pt2Os catalyst showed two-fold higher activity at 25 degrees C than pure Pt and that the alloy had 272% improved stability, validating our theoretical predictions.</p> <p>We also carried out similar QM studies followed by experimental validation for the Os/Pt core-shell catalyst fabricated by the underpotential deposition (UPD) method. The QM results indicated that the RDS for ORR is a compromise between the OOH formation step (0.37 eV for Pt, 0.23 eV for Pt<sub>2ML</sub>/Os core-shell) and H<sub>2</sub>O formation steps (0.32 eV for Pt, 0.22 eV for Pt<sub>2ML</sub>/Os core-shell). We found that Pt<sub>2ML</sub>/Os has the highest activity (compared to pure Pt and to the Pt<sub>3</sub>Os alloy) because the 0.37 eV barrier decreases to 0.23 eV. To understand what aspects of the core shell structure lead to this improved performance, we considered the effect on ORR of compressing the alloy slab to the dimensions of pure Pt. However this had little effect, with the same RDS barrier 0.37 eV. This shows that the ligand effect (the electronic structure modification resulting from the Os substrate) plays a more important role than the strain effect, and is responsible for the improved activity of the core- shell catalyst. Experimental materials characterization proves the core-shell feature of our catalyst. The electrochemical experiment for Pt<sub>2ML</sub>/Os/C showed 3.5 to 5 times better ORR activity at 0.9V (vs. NHE) in 0.1M HClO<sub>4</sub> solution at 25 degrees C as compared to those of commercially available Pt/C. The excellent correlation between experimental half potential and the OH binding energies and RDS barriers validate the feasibility of predicting catalyst activity using QM calculation and a simple LangmuirHinshelwood model.</p> <p>In part II, we used QM calculations to study methane stream reforming on a Ni-alloy catalyst surfaces for solid oxide fuel cell (SOFC) application. SOFC has wide fuel adaptability but the coking and sulfur poisoning will reduce its stability. Experimental results suggested that the Ni4Fe alloy improves both its activity and stability compared to pure Ni. To understand the atomistic origin of this, we carried out QM calculations on surface segregation and found that the most stable configuration for Ni<sub>4</sub>Fe has a Fe atom distribution of (0%, 50%, 25%, 25%, 0%) starting at the bottom layer. We calculated that the binding of C atoms on the Ni4Fe surface is 142.9 Kcal/mol, which is about 10 Kcal/mol weaker compared to the pure Ni surface. This weaker C binding energy is expected to make coke formation less favorable, explaining why Ni<sub>4</sub>Fe has better coking resistance. This result confirms the experimental observation. The reaction energy barriers for CHx decomposition and C binding on various alloy surface, Ni<sub>4</sub>X (X=Fe, Co, Mn, and Mo), showed Ni<sub>4</sub>Fe, Ni<sub>4</sub>Co, and Fe<sub>4</sub>Mn all have better coking resistance than pure Ni, but that only Ni<sub>4</sub>Fe and Fe<sub>4</sub>Mn have (slightly) improved activity compared to pure Ni.</p> <p>In part III, we used QM to examine the proton transport in doped perovskite-ceramics. Here we used a 2x2x2 supercell of perovskite with composition Ba<sub>8</sub>X<sub>7</sub>M<sub>1</sub>(OH)<sub>1</sub>O<sub>23</sub> where X=Ce or Zr and M=Y, Gd, or Dy. Thus in each case a 4<sup>+</sup> X is replace by a 3<sup>+</sup> M plus a proton on one O. Here we predicted the barriers for proton diffusion allowing both includes intra-octahedron and inter-octahedra proton transfer. Without any restriction, we only observed the inter-octahedra proton transfer with similar energy barrier as previous computational work but 0.2 eV higher than experimental result for Y doped zirconate. For one restriction in our calculations is that the O<sub>donor</sub>-O<sub>acceptor</sub> atoms were kept at fixed distances, we found that the barrier difference between cerates/zirconates with various dopants are only 0.02~0.03 eV. To fully address performance one would need to examine proton transfer at grain boundaries, which will require larger scale ReaxFF reactive dynamics for systems with millions of atoms. The QM calculations used here will be used to train the ReaxFF force field.</p>

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<p>The two lowest T = 3/2 levels in <sup>21</sup>Na have been studied in the <sup>19</sup>F(<sup>3</sup>He, n), <sup>20</sup>Ne (p,p) and <sup>20</sup>Ne (p,p) reactions, and their excitation energies, spins, parities and widths have been determined. In a separate investigation, branching ratios were measured for the isospin-nonconserving particle decays of the lowest T = 3/2 levels in <sup>17</sup>O and <sup>17</sup>F to the ground state and first two excited states of <sup>16</sup>O, by studying the <sup>15</sup>N(<sup>3</sup>He,n) <sup>17</sup>F*(p) <sup>16</sup>O and <sup>18</sup>O(<sup>3</sup>He, )<sup>17</sup>O*(n) <sup>16</sup>O reactions.</p> <p>The <sup>19</sup>F(<sup>3</sup>He,n) <sup>21</sup>Na reaction was studied at incident energies between 4.2 and 5.9 MeV using a pulsed-beam neutron-time-of-flight spectrometer. Two T = 3/2 levels were identified at excitation energies of 8.99 0.05 MeV (J > ) and 9.22 0.015 MeV (J<sup> </sup> = <sup>+</sup>, 40 keV). The spins and parities were determined by a comparison of the measured angular distributions with the results of DWBA calculations. </p> <p>These two levels were also obsesrved as isospin-forbidden resonances in the <sup>20</sup>Ne(p,p) and <sup>20</sup>Ne(p,p) reactions. Excitation energies were measured and spins, parities, and widths were determined from a single level dispersion theory analysis. The following results were obtained:</p> <p>E<sub>x</sub> = 8.973 0.007 MeV, J<sup> </sup> = 5/2 <sup>+</sup> or 3/2<sup>+</sup>, 1.2 keV,</p> <p><sup></sup>p<sub>o</sub> = 0.1 0.05 keV; E<sub>x</sub> = 9.217 0.007 MeV, J<sup></sup> = <sup>+</sup>,</p> <p> = 2.3 0.5 keV, <sup></sup>p<sub>o</sub> = 1.1 0.3 keV.</p> <p>Isospin assignments were made on the basis of excitation energies, spins, parities, and widths.</p> <p>Branching ratios for the isospin-nonconserving proton decays of the 11.20 MeV, T = 3/2 level in <sup>17</sup>F were measured by the <sup>15</sup>N(<sup>3</sup>He,n) <sup>17</sup> F*(p) <sup>16</sup>O reaction to be 0.088 0.016 to the ground state of <sup>16</sup>O and 0.22 0.04 to the unresolved 6.05 and 6.13 MeV levels of <sup>16</sup>O. Branching ratios for the neutron decays of the analogous T = 3/2 level, at 11.08 MeV in <sup>17</sup>O, were measured by the <sup>16</sup>O(<sup>3</sup>He, )<sup>17</sup>O*(n)<sup>16</sup>O reaction to be 0.91 0.15 to the ground state of <sup>16</sup>O and 0.05 0.02 to the unresolved 6.05 and 6.13 MeV states. By comparing the ratios of reduced widths for the mirror decays, the form of the isospin impurity in the T = 3/2 levels is shown to depend on T<sub>z</sub>.</p>

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La Ciencia y Tecnologa de Materiales tiene el reto permanente de desarrollar y mejorar materiales multifuncionales y respetuosos con el medio ambiente. En este sentido, los materiales de tipo MOF (Metal-Organic Framework) estn siendo objeto de un gran inters, ya que las redes slidas de coordinacin (especialmente, las porosas) presentan aplicaciones en campos en los que la sociedad manifiesta una demanda creciente de ciencia y tecnologa, como el almacenamiento y transporte de energa, la captura de gases con efecto invernadero, la catlisis heterognea y la liberacin controlada de frmacos, entre otros. En este contexto, el presente trabajo se plante con el objetivo de desarrollar nuevos materiales de tipo MOF basados en metaloporfirinas, al objeto de mimetizar las funciones que desempean las mismas en los sistemas biolgicos, con el fin de reproducirlas en el estado slido. Para ello, se han escogido biometales como el hierro y el cobalto: caractersticos de estos sistemas, de bajo coste y medioambientalmente respetuosos. Por otra parte, las porfirinas seleccionadas han sido las siguientes: TPP (meso-tetra-4-fenilporfirina), TCPP (meso-tetra-4-carboxifenilporfirina) y TPPS (meso-tetra-4-sulfonatofenilporfirina). Estas tres molculas conforman un conjunto de ligandos que difieren ligeramente en sus grupos funcionales. Asimismo, en ocasiones, se ha utilizado un ligando secundario dipiridnico (4,4-bipiridina) que ha actuado como espaciador. El diseo de las sntesis se ha centrado tanto en las combinaciones adecuadas de metales y ligandos como en la seleccin de las tcnicas de sntesis. As, se han obtenido cinco nuevos compuestos, que se han sintetizado en condiciones solvotermales suaves o mediante radiacin microondas. La caracterizacin preliminar de los mismos se ha llevado a cabo mediante anlisis cuantitativo, espectroscopia infrarroja y Raman, difraccin y fluorescencia de rayos X y medidas de densidad. El estudio estructural se ha realizado mediante difractometra de rayos X y el estudio trmico se ha llevado a cabo mediante termogravimetra y termodifractometra. En los casos en que ha resultado procedente, tambin se han caracterizado los compuestos mediante espectroscopia ultravioleta-visible (UV-Vis), Mssbauer y resonancia paramagntica electrnica (EPR) y mediante medidas de la susceptibilidad magntica. Asimismo, ocasionalmente, se han realizado clculos mecano-cunticos basados en la teora del funcional de la densidad (DFT) y medidas catalticas. El primero de los cinco compuestos obtenidos, de frmula [FeTCPP], es quiral y destaca por ser la tercera estructura 2D publicada basada en esta porfirina. La formacin de este compuesto est condicionada por la oxidacin de los iones de hierro y por la existencia de grupos carboxlicos en la porfirina. Por otra parte, con la participacin del espaciador 4,4-bipiridina (bipy) se han obtenido tres redes 1D. As, la estructura cristalina del compuesto ([FeTPPbipy])n se explica mediante la formacin de radicales neutros que se estabilizan en un empaquetamiento que permite la formacin de enlaces entre los grupos fenlicos de distintas cadenas. La formacin de estos enlaces queda corroborada por la existencia de significativas interacciones antiferromagnticas. Por otra parte, en el compuesto [CoTPP(bipy)]([CoTPP])0.22(TPP)0.78, la disposicin de las cadenas deja grandes huecos en la red que se ocupan con porfirinas tanto coordinadas como sin coordinar. El tercero de estos compuestos 1D presenta la frmula [CoTPPS0.5(bipy)(H2O)2]6H2O y destaca porque la extensin de las cadenas se produce por la alternancia de dos tipos de octaedros de CoII. La naturaleza de los grupos sulfonato de la porfirina TPPS es determinante para comprender la intrincada red de enlaces de hidrgeno de este compuesto, que propician la formacin de una red interpenetrada caracterizada por su gran estabilidad trmica (hasta los 370C). Finalmente, con la porfirina TCPP se ha obtenido un segundo compuesto de frmula -O-[FeTCPP]2nDMF (n 16; DMF = dimetilformamida). El mismo presenta grandes cavidades (47% de porosidad) que diluyen la matriz magntica, caracterizada por fuertes interacciones antiferromagnticas intradimricas. Todo ello revela una inusual estructura superhiperfina, observada por espectroscopia EPR. El trabajo que se recoge en esta memoria constituye, por lo tanto, un viaje de mayor a menor dimensionalidad en las estructuras cristalinas. La gua de este viaje ha sido la bsqueda de propiedades catalticas en sistemas heterogneos. As, el [CoTPP(bipy)]([CoTPP])0.22(TPP)0.78 obedece el enfoque de inmovilizar o anclar el catalizador en los huecos de la red. Sin embargo, la estrategia alternativa seguida para el compuesto m-O-[FeTCPP]2nDMF (es decir, que el propio MOF acte de catalizador) es la que ha aportado mejores y ms prometedores resultados en lo que a catlisis heterognea se refiere.

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Graded-index (GRIN) fiber lens arrays are fabricated from commercial GRIN fibers to collimate a high-power laser diode array. The beam divergence angles are reduced to 4.2 and 14.7 mrad in the fast and slow axes, respectively. The influences of smile and fluctuation in fiber length are discussed. Using an aspherical focal lens system, about 74% power can be launched into a fiber with a numerical aperture (NA) of 0.22 and a core diameter of 400 mu m. (c) 2008 Society of Photo-Optical Instrumentation Engineers.

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Neste trabalho estudamos o problema da segregao de impurezas substitucionais em sistemas nanoestruturados metlicos formados pela justaposio de camadas (multicamadas). Utilizamos o modelo de ligaes fortes (tight-binding) com um orbital por stio para calcular a estrutura eletrnica desses sistemas, considerando a rede cristalina cubica simples em duas direes de crescimento: (001) e (011). Devido perda de simetria do sistema, escrevemos o hamiltoniano em termos de um vetor de onda k, paralelo ao plano, e um &#305;ndice l que denota um plano arbitrario do sistema. Primeiramente, calculamos a estrutura eletrnica do sistema considerando-o formado por tomos do tipo A e, posteriormente, investigamos as modificaes nessa estrutura eletrnica ao introduzirmos uma impureza do tipo B em um plano arbitrrio do sistema. Calculamos o potencial introduzido por esta impureza levando-se em conta a neutralidade de carga atravs da regra de soma de Friedel. Calculamos a variao da energia eletrnica total &#916;El como funo da posio da impureza. Como substrato, consideramos sistemas com ocupaes iguais a 0.94 e 0.54 eltrons por banda, o que dentro do modelo nos permite cham-los de Nie Cr. As impurezas sao tambem metais de transio - Mn, Fee Co. Em todos os casos investigados, foi verificado que a variao de energia eletrnica total apresenta um comportamento oscilatorio em funo da posio da impureza no sistema, desde o plano superficial, at vrios planos interiores do sistema. Como resultado, verificamos a ocorrencia de planos mais favorveis localizao da impureza. Ao considerarmos um nmero relativamente grande de planos, um caso em particular foi destacado pelo aparecimento de um batimentono comportamento oscilatrio de &#916;El. Estudamos tambm o comportamento da variao da energia total, quando camadas (filmes) so crescidas sobre o substrato e uma impureza do mesmo tipo das camadas colocada no substrato. Levamos em conta a diferena de tamanho entre os tomos do substrato e os tomos dos filmes. Analisamos ainda a influncia da temperatura sobre o comportamento oscilatrio da energia total, considerando a expanso de Sommerfeld.

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INTRODUO: As chances de adoecer e de mortalidade so maiores, em crianas com estado nutricional (EN) inadequado nos primeiros meses de vida. Fatores de risco para o EN inadequado, incluem os aspectos psicossociais maternos, como a ansiedade, a depresso ps-parto (DPP), a ausncia de suporte social. No entanto, so poucos os estudos sobre o papel destes fatores na determinao do EN infantil e seus resultados controversos. OBJETIVO: Investigar a relao entre depresso no ps-parto e o estado nutricional infantil inadequado no segundo ms de vida. MTODOS: Trata-se de um estudo seccional com 466 crianas aos dois meses de vida (mdia= 65 dias; DP=0,5) oriundas de unidades bsicas de sade do municpio do Rio de Janeiro, realizado entre junho de 2005 e dezembro de 2009. Para compor o desfecho, mdias de peso-para-idade foram expressas em escores z e comparadas s informaes da nova curva de referncia WHO (2006) para menores de cinco anos. Foram classificadas como estado nutricional inadequado, crianas com escore z abaixo de -2, baixo peso-para-idade, e crianas com escore z acima de +2, excesso de peso-para- idade. Informaes referentes DPP foram obtidas por meio da aplicao da verso em portugus do instrumento EPDS (Edinburgh Postnatal Depression Scale). As anlises das associaes entre a DPP e os desfechos foram verificadas via modelos de regresso logstica multinomial, mediante estimativas de razes de chances (OR) brutas e ajustadas e seus respectivos intervalos de confiana de 95% (IC 95). RESULTADOS: A amostra revelou escores z mdios de -0,22 para peso-para-idade, 4,51%(n=21) apresentaram baixo peso-para- idade e 1,72% (n=8) de excesso de peso-para-idade. A prevalncia de depresso foi de 27,6%. Nas anlises brutas, filhos de mes deprimidas apresentavam 2,45 mais chance (OR=2,45; I.C. 95%=1,01-5,93;p-valor=0,050) de baixo peso-para-idade e 0,38 chance de excesso de peso-para-idade (OR=0,38;I.C. 95%=0,04-3,17;p-valor=0,38), do que os filhos de mes no deprimidas, porm esta associao apresentou nvel de significncia maior que 5%. Aps ajuste pelo peso ao nascer, condies ambientais, posse de utenslios, prematuridade, idade materna e escolaridade materna a associao entre depresso e estado nutricional infantil no apresentou significncia estatstica (OR=2,39;I.C. 95%=0,74-7,71;p- valor>0,05).CONCLUSO: A DPP no foi associada ao estado nutricional infantil.

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LiB3O5LBO1064nm532nm1064nm00014532nm00004651064nm022532nm08731064nm024532nm022

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Hipertensos tm rarefao capilar e disfuno endotelial microcirculatria, tornando-se mais vulnerveis a leses em rgos-alvo. O estudo buscou avaliar o efeito de seis meses de tratamento farmacolgico sobre densidade capilar e reatividade microvascular a estmulos fisiolgicos e farmacolgicos em hipertensos de baixo risco cardiovascular. Secundariamente testou-se a existncia de diversidade nas respostas a diferentes estratgias anti-hipertensivas. Foram recrutados 44 pacientes, com 46,71,3 anos e 20 normotensos com 48,01,6 anos. Avaliaram-se dados antropomtricos e laboratoriais e dosaram-se no soro o fator de crescimento vascular endotelial (VEGF), receptor Flt-1 para VEGF e xido ntrico (NO). A contagem capilar foi por microscopia intravital, captando-se imagens da microcirculao no dorso da falange do dedo mdio e contando os capilares com programa especfico. Repetia-se o procedimento aps hiperemia reativa ps-oclusiva (HRPO) para avaliar o recrutamento capilar. A reatividade vascular foi testada por fluxometria Laser Doppler, iontoforese de acetilcolina (Ach), HRPO e hiperemia trmica local (HTL). Os pacientes foram distribudos aleatoriamente para dois grupos de tratamento: succinato de metoprolol titulado a 100 mg dirios ou olmesartana medoxomila titulada a 40 mg dirios, empregando-se, se necessrio, a hidroclorotiazida. Os controles seguiram o mesmo protocolo inicial e aps seis meses todos os testes foram repetidos nos hipertensos. As variveis clnicas e laboratoriais basais eram semelhantes em comparao aos controles e entre os dois grupos de tratamento. Aps seis meses, havia pequenas diferenas entre os grupos na relao cintura-quadril e HDL. A densidade capilar antes do tratamento era significativamente menor que no grupo controle (71,31,5 vs 80,61,8 cap/mm2 p<0,001 e HRPO 71,71,5 vs 79,52,6 cap/mm2 p<0,05) e, com o tratamento, aumentou para 75,41,1 cap/mm2 (p<0,01) no estado basal e para 76,81,1 cap/mm2 HRPO (p<0,05). reatividade vascular, a condutncia vascular cutnea (CVC) em unidades de perfuso (UP)/mmHg era similar HTL nos controles e hipertensos e aumentou com o tratamento nos dois subgrupos (metoprolol:1,730,2 a 1,900,2 p<0,001 e olmesartana:1,490,1 a 1,870,1 p<0,001). A CVC mxima HRPO era menor nos hipertensos: 0,30(0,22-0,39) que nos controles: 0,39(0,31-0,49) com p<0,001. Aps tratamento, aumentou para 0,41(0,29-0,51) com p<0,001. O aumento foi significativo apenas no grupo olmesartana (0,290,02 a 0,420,04 p<0,001). A diferena entre o tempo para atingir o fluxo mximo HRPO aumentou no grupo metoprolol aps tratamento 3,0 (-0,3 a 8,8) segundos versus olmesartana 0,4 (-2,1 a 2,4) segundos p<0,001. iontoforese, a rea sob a curva de fluxo (AUC) era similar nos grupos e aumentou com o tratamento, de 6087(3857-9137) para 7296(5577-10921) UP/s p=0,04. O VEGF e receptor no diferiam dos controles nem sofreram variaes. A concentrao de NO era maior nos hipertensos que nos controles: 64,9 (46,8-117,6) vs 50,7 (42-57,5) M/dl p=0,02 e no variou com tratamento. Em concluso, hipertensos de baixo risco tm menor densidade e menor recrutamento capilar e ambos aumentam com tratamento. Apresentam tambm disfuno endotelial microcirculatria que melhora com a terapia.

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Although the Florida pompano (Trachinotus carolinus) is a prime candidate for aquaculture, the problematic production of juveniles remains a major impediment to commercial culture of this species. In order to improve the understanding of larval development and to refine hatchery production techniques, this study was conducted to characterize development and growth of Florida pompano from hatching through metamorphosis by using digital photography and image analysis. Newly hatched larvae were transparent and had a large, elongate yolk sac and single oil globule. The lower and upper jaws as well as the digestive tract were not fully developed at hatching. Rotifers were observed in the stomach of larvae at three days after hatching (DAH), and Artemia spp. were observed in the stomach of larvae at 14 DAH. Growth rates calculated from total length measurements were 0.22 0.04, 0.23 0.12, and 0.35 0.09 mm/d for each of the larval rearing trials. The mouth gape of larvae was 0.266 0.075 mm at first feeding and increased with a growth rate of 0.13 0.04 mm/d. Predicted values for optimal prey sizes ranged from 80 to 130 m at 3 DAH, 160 to 267 m at 5 DAH, and 454 to 757 m at 10 DAH. Based on the findings of this study, a refined feeding regime was developed to provide stage- and size-specific guidelines for feeding Florida pompano larvae reared under hatchery con

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Comunicacin a congreso (pster): XXIV Simposio del Grupo Especializado de Cristalografa y Crecimiento Cristalino, GE3C. 23-26 de junio de 2014, Bilbao

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Aquaculture in Africa is fairly insignificant by world standards and accounts for a mere 0.4 per cent of global aquaculture production. The application of genetics can play an important role in efforts to increase aquaculture production in Africa through methods such as selective breeding, hybridization, chromosome manipulation and use of YY supermales&rdquo;. Other issues that need to be addressed are limited genetic research facilities, funding, human capacity and suitable species for aquaculture.

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Estimates for the growth parameters (L sub( infinity ) and K) mortality coefficients (Z,M and F) and exploitation rate (E) for the sciaenid Plagioscion squamosissimus are presented. The following results were obtained: 1) for male: L sub( arrow right )=44.2 cm, K=0.30 yr super(1), Z=0.82 yr super(1), M=0.66 yr super(1), F=0.16 yr super(1), and E=0.20; and 2) for females: L sub( arrow right )=68.4, K=0.22 yr super(1), Z=0.91 yr super(1), M=0.47 yr super(1), F=0.44 yr super(1) and E=0.49. Females are more heavily fished than males. Artisanal fishing carried out with gillnets, is mainly directed toward the young section of the population and individuals reproducing for the first time.