Holy Face

Gerard David; 3 35/64 in.x 2 1/8 in.; tempera and gold leaf on parchment that has been trimmed and laid down on thin walnut

Beyond the Bauhaus : Cultural Modernity in Breslau, 1918-1933 /

The Breslau arts scene during the Weimar period was one of the most vibrant in all of Germany, yet it has disappeared from memory and historiography. Breslau was a key center for innovative artistic production during the Weimar Republic; recovery of its history will shed new light on German cultural dynamics in the 1920s. Such a study has art historical significance because of the incredible extent of innovation that occurred in almost every intellectual field, advances that formed the basis for aesthetic modernism internationally and continue to affect the course of visual art and architecture today. Architecture education, just one example in many, is still largely based on a combination of the Bauhaus model from the 1920s and the model developed at the Breslau Academy of Fine and Applied Art. The exploratory attitude encouraged in Weimar era arts endeavors, as opposed to the conformism of academic art, is still a core value promoted in contemporary art and architecture circles. Given the long-lasting influence of Weimar culture on modernism one would expect to find a spate of studies examining every aspect of its cultural production, but this is not the case. Recent scholarship is almost exclusively focused on Berlin and the Dessau Bauhaus. Although both interests are understandable, the creative explosion was not confined to these cities but was part of a larger cultural ethos that extended into many of the smaller regional centers. The Expressionist associations the Blaue Reiter in Munich and Brücke in Dresden are two well-known examples. Equally, innovation was not confined to a few monumental projects like the Stuttgart Weissenhofsiedlung but part of a broader national cultural ethos. The dispersion of modernism occurred partly because of the political history of Germany as a loosely joined confederation of small city states and principalities that had strong individual cultural identities before unification in 1871 but also because of the German propensity to value and take intense pride in the Heimat, understood both as the hometown and the region. Heimatliebe translated into generous support for cultural institutions in outlying cities. Host to a roster of internationally acclaimed artists and architects, major collectors, arts organizations, museums, presses, galleries, and one of the premier German arts academies of the day, Breslau boasted a thriving modern arts scene until 1933 when the Nazis began their assault on so-called "degenerate" art. This book charts the cultural production of Breslau-based artists, architects, art collectors, urban designers, and arts educators, who were especially interesting because they operated in the space between the margins of Weimar-era cultural debates. Rather than accepting the radical position of the German avant-garde or the reactionary position of German conservatives, many Breslauers sought a middle ground. It is the first book in English to address this history and presents the history in a manner unique to any studies currently on the market. 'Beyond the Bauhaus' explores the polyvalent and contradictory nature of cultural production in Breslau in order to expand the cultural and geographic scope of Weimar history; the book asserts a reciprocal dimension to the relationship between regional culture and national culture, between centers like Breslau and the capital Berlin. With major international figures like the painters Otto Mueller and Oskar Moll, architects Hans Scharoun and Adolf Rading, urban planners Max Berg and Ernst May, collectors Ismar Littmann and Max Silberberg, and an art academy that by 1929 was considered the best in Germany, Breslau clearly had significance to narratives of Weimar cultural production. 'Beyond the Bauhaus' contributes the history of German culture during the Weimar Republic. It belongs alongside histories of art, architecture, urban design, exhibition, collecting, and culture; histories of the Bauhaus; histories of arts education more broadly; and German history. The readership would include those interested in German history; German art, architecture, urban design, planning, collecting, and exhibition history; in the avant-garde; the development of arts academies and arts pedagogy; and the history of Breslau and Silesia.

An address delivered on the dedication of the cemetery at Mount Auburn, September 24, 1831 /

Address before Massachusetts Horticultural Society.

The dramatic works of Shackerley Marmion,

Prefactory notice signed: James Maidment, W. H. Logan.

Chronic shallow seawater circulation driven by subsurface gas dynamics, at the Southern Hydrate Ridge seep system, Cascadia

Senior thesis written for Oceanography 445

Systemic gene expression in arabidopsis during an incompatible interaction with Alternaria brassicicola

Pathogen challenge can trigger an integrated set of signal transduction pathways, which ultimately leads to a state of high alert, otherwise known as systemic or induced resistance in tissue remote to the initial infection. Although large-scale gene expression during systemic acquired resistance, which is induced by salicylic acid or necrotizing pathogens has been previously reported using a bacterial pathogen, the nature of systemic defense responses triggered by an incompatible necrotrophic fungal pathogen is not known. We examined transcriptional changes that occur during systemic defense responses in Arabidopsis plants inoculated with the incompatible fungal pathogen Alternaria brassicicola. Substantial changes (2.00-fold and statistically significant) were demonstrated in distal tissue of inoculated plants for 35 genes (25 up-regulated and 10 down-regulated), and expression of a selected subset of systemically expressed genes was confirmed using real-time quantitative polymerase chain reaction. Genes with altered expression in distal tissue included those with putative functions in cellular housekeeping, indicating that plants modify these vital processes to facilitate a coordinated response to pathogen attack. Transcriptional up-regulation of genes encoding enzymes functioning in the beta-oxidation pathway of fatty acids was particularly interesting. Transcriptional up-regulation was also observed for genes involved in cell wall synthesis and modification and genes putatively involved in signal transduction. The results of this study, therefore, confirm the notion that distal tissue of a pathogen-challenged plant has a heightened preparedness for subsequent pathogen attacks.

A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse

The c-fms gene encodes the receptor for macrophage colony-stimulating factor (CSF-1). The gene is expressed selectively in the macrophage and trophoblast cell lineages. Previous studies have indicated that sequences in intron 2 control transcript elongation in tissue-specific and regulated expression of c-fms. In humans, an alternative promoter was implicated in expression of the gene in trophoblasts. We show that in mice, c-fms transcripts in trophoblasts initiate from multiple points within the 2-kilobase (kb) region flanking the first coding exon. A reporter gene construct containing 3.5 kb of 5' flanking sequence and the down-stream intron 2 directed expression of enhanced green fluorescent protein (EGFP) to both trophoblasts and macrophages. EGFP was detected in trophoblasts from the earliest stage of implantation examined at embryonic day 7.5. During embryonic development, EGFP highlighted the large numbers of c-fms-positive macrophages, including those that originate from the yolk sac. In adult mice, EGFP location Was consistent with known F4/80-positive macrophage populations, including Langerhans cells of the skin, and permitted convenient sorting of isolated tissue macrophages from disaggregated tissue. Expression of EGFP in transgenic mice was dependent on intron 2 as no lines with detectable EGFP expression were obtained where either all of intron 2 or a conserved enhancer element FIRE (the Fms intronic regulatory element) was removed. We have therefore defined the elements required to generate myeloid- and trophoblast-specific transgenes as well as a model system for the study of mononuclear phagocyte development and function. (C) 2003 by The American Society of Hematology.

Upregulation of beta catenin in superior frontal cortex of chronic alcoholics

Chronic alcohol abuse causes neurotoxicity and the development of tolerance and dependence. At the molecular level, however, knowledge about mechanisms underlying alcoholism remains limited. In this study we examined the superior frontal cortex, one of the most vulnerable brain regions, of alcoholics and of age- and gender-matched control subjects by means of antibody microarrays and Western blot analyses, and identified an up-regulation of beta-catenin level in the superior frontal cortex of alcoholics. Beta-catenin is the orthologue of the Drosophila armadillo segment polarity gene and a down stream component of the Wnt and Akt signaling pathway. Beta-catenin was identified as a cell adhesion molecule of the cadherin family which binds to the actin cytoskeleton. Genetic and biochemical analyses also found that beta-catenin can be translocated from the cytoplasm to the nucleus and acts as a transcription factor. In addition, electron microscopy performed on rat brain tissue sections has localized the beta-catenin and cadherin complexes to the synapses where they border the active zone. Because of the multi-functional role of beta-catenin in the nervous system, this study provides the premise for further investigation of mechanisms underlying the up-regulation of beta-catenin in alcoholism, which may have considerable pathogenic and therapeutic relevance.

RELIGIÃO E COTIDIANO NA CIDADE DE ALTO PARAÍSO (RONDÔNIA)

O objetivo da presente pesquisa é explicitar a relação entre a religião e a vida cotidiana na cid ade de Alto Paraíso (RO). Pretende discutir o papel do imaginário religioso no processo de ocupação de um novo espaço geográfico e na luta pela sobrevivência neste contexto. Sistematiza, assim, a história de uma cidade a partir de depoimentos de seus primeiros habitantes, perguntando pelo lugar da religião nesta memória. A metodologia privilegia o depoimento oral, colhido através da técnica de entrevistas, transcritas, sistematizadas e problematizadas como fonte plausível de investigação. Tenta captar e visibilizar os sentidos que sujeitos anônimos atribuem a suas experiências de vida num processo de transformação de um espaço inóspito em um lugar habitável e promissor em termos econômicos e sociais. A pesquisa está dividida em três capítulos. O primeiro sistematiza a história de Alto Paraíso, privilegiando a memória dos primeiros moradores da região. O segundo debate a religião como agente na formação do imaginário e das transformações sociais. O terceiro capítulo discute o embricamento entre o trânsito religioso, as magias populares e os milagres institucionalizados.(AU)

A INCLUSÃO SOCIAL E AS MEDIAÇÕES NA RECEPÇÃO DA COMUNICAÇÃO MERCADOLÓGICA TELEVISIVA POR PESSOAS COM DEFICIÊNCIA VISUAL

Este trabalho é estimulado pela reflexão sobre a recepção da comunicação mercadológica televisiva por pessoas com deficiência visual, assim como sobre a percepção quanto às iniciativas do governo e das empresas em prol da inclusão. O estudo busca, com base na Teoria das Mediações, que é estudada por teóricos dos Estudos de Recepção, entender de que forma as pessoas com deficiência visual interagem com as diferentes categorias de comerciais de televisão, a partir de seus valores, percepções de mundo e condições em que se encontram. Deste modo, observa-se ainda o nível de sentimento de pertencimento das pessoas com deficiência visual quanto à preocupação do governo e das empresas em causas sociais. Os procedimentos que dirigem a investigação caracterizam-se por uma reflexão a partir de dados decorrentes de pesquisa bibliográfica, articulada a uma pesquisa de campo de natureza qualitativa. O trabalho conclui que a percepção das pessoas com deficiência visual se distancia do que está sendo proposto, feito e aparentemente sendo bem divulgado em prol da inclusão; bem como, observa a necessidade de aprimoramento da conscientização da sociedade, e consequentemente dos comunicadores, sobre a importância da aproximação entre as pessoas com deficiência visual e a comunicação mercadológica televisiva. Nesta percepção, o trabalho apresenta sugestões no âmbito comunicacional que poderiam tornar as causas sociais realmente expressivas na vida das pessoas com deficiência visual.

EDUCAÇÃO E CONTROLE SOCIAL NA PRIMEIRA DÉCADA REPUBLICANA

O presente trabalho tem como objetivo o estudo da rebeldia negra nos anos antecedentes a escravidão e suas conseqüências, tanto social como educacional. O fato da Província de São Paulo ter se tornado uma grande exportadora de café fez dela um forte centro escravocrata. Não se pode negar a influência de quatro séculos de escravidão, nem tão pouco seus efeitos sobre a nação. Em 13 de maio de 1888 fora decretada a abolição, e esta medida lançou nas ruas uma multidão de negros livres sem qualquer perspectiva de futuro. Não foram preparados para viver em liberdade, a sociedade não estava organizada para recebê-los como trabalhadores livres e pagar por seu trabalho. Ao olhar de muitos eram tidos como preguiçosos, vadios e desordeiros. Nunca foram tratados como iguais, mas sim como uma raça medíocre e inferior, onde a imoralidade e os excessos chegam a um ponto irreversível, caso não sejam controlados. Diante dessa situação, fazia-se necessário traçar planos para conter os excessos e o furor da grande massa de libertos soltos pelas ruas, torna-se de extrema urgência a utilização de meios diversos a fim de manter o controle social, inculcando na mente da população negra os malefícios causados pelas revoltas, o dever de trabalhar, o abandono dos vícios. Para tanto, os intelectuais, políticos e os grandes exportadores (que representavam o poder econômico da época), passam a utilizar-se de diversos meios para propagação dos valores republicanos, jornais, conferências políticas, boletins e também o sistema educacional. Por meios de livros de leitura, artigos em revistas educacionais, adição de novas disciplinas no currículo escolar e até mesmo a ação do professor em sala de aula visavam a docilização dos costumes do povo. Os republicanos que assumiram o poder político do país não estavam apenas preocupados em educar os poucos que tinham acesso à escolarização, mas também, através do exemplo, educar e acalmar os ânimos dos negros vadios e preguiçosos que não podiam freqüentar a escola. Daí resulta tamanha preocupação com o estabelecimento de regras, organização, respeito e punições no ambiente escolar recém reestruturado (AU)

CAPULANAS NA SALA DE AULA: OS SENTIDOS DA FORMAÇÃO DE EDUCADORES(AS) EM MOÇAMBIQUE

Este trabalho é um registro das histórias de vida de muitas pessoas. As histórias aqui apresentam identidades diferentes: fragmentos vividos e guardados como expressões culturais orais, escritos permeados pela emoção, imagens capturadas pelos encontros, tudo isso organizado e escrito ganha forma e significado com a possibilidade desse trabalho. À medida que os encontros foram oportunizados iniciaram-se outros momentos que se desdobraram em muitos mais. A implantação do Programa Alfabetização Solidária em Moçambique, PASMO, viabilizou que essa experiência fosse investigada para identificar os sentidos da formação de educadores(as) no Brasil e em Moçambique. O objetivo desse trabalho centrou-se no desenvolvimento de nova proposta para a formação de educadores(as) em Moçambique, na África, tendo como tema central os encontros entre profissionais de educação que passaram a transitar por contextos diferenciados, envolvendo países, culturas, línguas e outras formas de comunicação. Ênfase na construção de conhecimento foi dada à cultura local, línguas moçambicanas e oralidade. A inserção de mulheres moçambicanas mostrou-se importante como forma de apropriação e mobilidade social e cultural. Foi no espaço da sala de aula, nos fazeres próprios da docência e no encontro com educadores(as), que se construiu e re-construiu conhecimentos específicos que sinalizaram para novas práticas pedagógicas. Os encontros promovidos pela educação conduziram a caminhos e trilhas da formação de educadores(as), primeiro no Brasil, depois em Moçambique.(AU)

Avaliação do Índice de Maturação das Vértebras Cervicais em radiografias cefalométricas laterais, tomadas com diferentes posicionamentos de cabeça

Este trabalho teve como finalidade avaliar a fase de crescimento em uma amostra de 49 pacientes, com idades variando de 9 a 15 anos, observando as vértebras cervicais em radiografias laterais, tomadas na posição natural de cabeça (PNC) e com erros de posicionamento, com inclinações de cabeça de 15o para cima (PNC-Alta) e de 15 o para baixo (PNC-Baixa), visando definir o quão importante isto é na precisão da avaliação da fase de crescimento. O teste kappa ponderado mostrou um grau de concordância substancial entre PNC e PNC-Alta e entre PNC e PNC-Baixa. Já o teste não paramétrico de wilcoxon (p<0,05) mostrou diferença estatisticamente significante entre essas comparações. Desta forma, a PNC demonstrou ser mais confiável na avaliação do Índice de Maturação das Vértebras Cervicais (IMVC), porém as telerradiografias com erro de posicionamento avaliadas não tiveram um grau de discordância que indicasse sua não utilização na clínica para predição de crescimento.(AU)

Spring Phenology of Butterflies : The role of seasonal variation in life-cycle regulation

Animals and plants in temperate regions must adapt their life cycle to pronounced seasonal variation. The research effort that has gone into studying these cyclical life history events, or phenological traits, has increased greatly in recent decades. As phenological traits are often correlated to temperature, they are relevant to study in terms of understanding the effect of short term environmental variation as well as long term climate change. Because of this, changes in phenology are the most obvious and among the most commonly reported responses to climate change. Moreover, phenological traits are important for fitness as they determine the biotic and abiotic environment an individual encounters. Fine-tuning of phenology allows for synchronisation at a local scale to mates, food resources and appropriate weather conditions. On a between-population scale, variation in phenology may reflect regional variation in climate. Such differences can not only give insights to life cycle adaptation, but also to how populations may respond to environmental change through time. This applies both on an ecological scale through phenotypic plasticity as well as an evolutionary scale through genetic adaptation. In this thesis I have used statistical and experimental methods to investigate both the larger geographical patterns as well as mechanisms of fine-tuning of phenology of several butterfly species. The main focus, however, is on the orange tip butterfly, Anthocharis cardamines, in Sweden and the United Kingdom. I show a contrasting effect of spring temperature and winter condition on spring phenology for three out of the five studied butterfly species. For A. cardamines there are population differences in traits responding to these environmental factors between and within Sweden and the UK that suggest adaptation to local environmental conditions. All populations show a strong negative plastic relationship between spring temperature and spring phenology, while the opposite is true for winter cold duration. Spring phenology is shifted earlier with increasing cold duration. The environmental variables show correlations, for example, during a warm year a short winter delays phenology while a warm spring speeds phenology up. Correlations between the environmental variables also occur through space, as the locations that have long winters also have cold springs. The combined effects of these two environmental variables cause a complex geographical pattern of phenology across the UK and Sweden. When predicting phenology with future climate change or interpreting larger geographical patterns one must therefore have a good enough understanding of how the phenology is controlled and take the relevant environmental factors in to account. In terms of the effect of phenological change, it should be discussed with regards to change in life cycle timing among interacting species. For example, the phenology of the host plants is important for A. cardamines fitness, and it is also the main determining factor for oviposition. In summary, this thesis shows that the broad geographical pattern of phenology of the butterflies is formed by counteracting environmental variables, but that there also are significant population differences that enable fine-tuning of phenology according to the seasonal progression and variation at the local scale.

The ontology: Chimaera or Pegasus

In the context of the needs of the Semantic Web and Knowledge Management, we consider what the requirements are of ontologies. The ontology as an artifact of knowledge representation is in danger of becoming a Chimera. We present a series of facts concerning the foundations on which automated ontology construction must build. We discuss a number of different functions that an ontology seeks to fulfill, and also a wish list of ideal functions. Our objective is to stimulate discussion as to the real requirements of ontology engineering and take the view that only a selective and restricted set of requirements will enable the beast to fly.