Implications of intrauterine protein malnutrition on prostate growth, maturation and aging

Aims Maternal malnutrition by low protein diet is associated with an increased incidence of metabolic disorders and decreased male fertility in adult life. This study aimed to assess the impact of maternal protein malnutrition (MPM) on prostate growth, tissue organization and lesion incidence with aging. Main methods Wistar rat dams were distributed into two groups, which were control (NP; fed a normal diet containing 17% protein) or a restricted protein diet (RP, fed a diet containing 6% protein) during gestation. After delivery all mothers and offspring received a normal diet. Biometrical parameters, hormonal levels and prostates were harvested at post-natal days (PND) 30, 120 and 360. Key findings MPM promoted low birth weight, decreased ano-genital distance (AGD) and reduced androgen plasma levels of male pups. Prostatic lobes from RP groups presented reduced glandular weight, epithelial cell height and alveolar diameter. The epithelial cell proliferation and collagen deposition were increased in RP group. Incidences of epithelial dysplasia and prostatitis were higher in the RP offspring than in the NP offspring at PND360. Significance Our findings show that MPM delays prostate development, growth and maturation until adulthood, probably as a result of low testosterone stimuli. The higher incidence of cellular dysplasia and prostatitis suggests that MPM increases prostate susceptibility to diseases with aging. © 2013 Elsevier Inc.

General outlines of the Organization of a Civil Registration Service in Latin America (English summary)

Organized by the United Nations, through its Statistical Office, the Bureau of Technical Assistance Operations, the Economic Commission for Latin America and the Latin American Demographic Centre, in co-operation with the Government of Peru, the Inter-American Statistical Institute, the Inter-American Children's Institute, the Pan American Health Organization and the Inter-American Civil Registration Association

Sítios assistenciais: modelo de organização e classificação de pacientes em UTI

Pós-graduação em Enfermagem (mestrado profissional) - FMB

A municipalização do Ensino Fundamental no município de Junqueirópolis/SP: o olhar dos profissionais do magistério sobre o processo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Proposta de etapas de implementação de WMS: um estudo de caso em um varejista moveleiro

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

As sesmarias em Portugal e no Brasil: a colonização do Brasil analisada por meio das cartas de doação e dos forais

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Informação e tecnologia para implantação do agroturismo em Echaporã - SP

Pós-graduação em Ciência da Informação - FFC

A trajetória legal dos mecanismos de gestão democrática no Estado de São Paulo: os caminhos percorridos

Pós-graduação em Educação - FFC

Imperialismo, petróleo e Revolução Bolivariana: impasses político-ideológicos do governo Chávez na Venezuela

Pós-graduação em Ciências Sociais - FFC

Latin American Metro and Subway Association (ALAMYS): a 15-year record of serving the citizenry

This issue of the Bulletin introduces the reader to the Latin American Metro and Subway Association (ALAMYS), which throughout its 15-year history has supported a variety of initiatives aimed at improving the quality of services provided by urban mass transit railway systems.At its most recent general assembly, held in Madrid, Spain, in December 2000, ALAMYS set up several technical committees to improve its operational efficiency so that it can progress as an organization and achieve its goals.This article was written by Aurelio Rojo Garrido, arojo@mail.metromadrid.es, current secretary general of ALAMYS and operations manager of Metro de Madrid, S.A.

Technical Notes on Trade Facilitation Measures

Towards the end of 2004, the members of the World Trade Organization (WTO) formally launched negotiations on trade facilitation on the basis of the modalities set out in Annex D of the July Package adopted in 2004. This mandate instructed members to clarify and improve three articles of the General Agreement on Tariffs and Trade (GATT), namely, article V on freedom of transit, article VIII on fees and formalities connected with importation and exportation, and article X on the publication and administration of trade regulations. To support these negotiations, the United Nations Conference on Trade and Development (UNCTAD) created a trust fund, with contributions from the Governments of Sweden and Spain . This fund has been used to develop a series of seminars and meetings and to produce a total of 20 technical notes on specific trade facilitation measures. These notes cover in particular facilitation measures that are topics of specific proposals that were made during WTO negotiations. This edition of the FAL Bulletin summarizes several of these technical notes, focusing mainly on customs-related issues.

Angústia e prazer nas relações de poder das organizações escolares

Pós-graduação em Psicologia - FCLAS

Formulação de um índice de qualidade de gestão de resíduos sólidos urbanos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Network for Cooperation in Integrated Water Resource Management for Sustainable Development in Latin America and the Caribbean No. 24

Editorial remarks.-- Open discussion: Integrating economics, legislation and administration in water and water services management ; Water and Free Trade Agreements ; Provision of transport infraestructure.-- News of the network: WALIR ; Prevention and reduction of the Danger Posed by natural disasters ; Ministry of Water in Bolivia ; Water management council of the Paute Basin in Ecuador ; CRSS.-- Internet and WWW news

O processo de desenvolvimento geoeconômico do complexo agroindustrial cooperativista na mesorregião norte central paranaense

Pós-graduação em Geografia - FCT