Pharmacokinetics of flavanone glycosides after ingestion of single doses of fresh-squeezed orange juice versus commercially processed orange juice in healthy humans

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Effect of potassium sources on the antioxidant activity of eggplant

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Crescimento e produção do maracujazeiro amarelo, sob diferentes fontes e doses de fósforo em cobertura

Brazil is the largest world producer of yellow passion fruit, a fruit crop which is exigent in nutrients, although little studied in relation to phosphorus fertilizing, fundamental on plant establishment. An experiment was carried out during the period of March/2010 to April/2011 in Remigio County, Paraiba State, Brazil, in order to evaluate the vegetative and productive attributes of yellow passion fruit plants under different sources and doses of phosphorus. Treatments were distributed in randomized blocks in tree replications and twelve plants by plot using the factorial design 2 x 5 referring the sources of superphosphate triple and superphosphate simple at levels P2O5 of 0, 12, 18, 24 and 30 g cave(-1). The following variables were recorded: stem diameter, number of productive branches, number of fruits per plant, fruit mass and fruit yield. The sources and doses of phosphorus affected growth and fruit production of yellow passion plants. The triple superphosphate is the most phosphorus efficient source for growth and fruit production of yellow passion fruit. The triple superphosphate dose which promoted the maximum yield of yellow passion fruit is 42.86 g.

Sistemas de cultivo antecessores e doses de nitrogênio em cobertura no feijoeiro em plantio direto = cover crop systems and nitrogen topdressing on common bean in no tillage

The objective of this work was to evaluate the grass cover crop production in crop systems involving maize and Urochloa ruziziensis, and the influence of topdressing nitrogen rates in the yield and agronomic efficiency on common-bean cultivated in succession in no-tillage. The experiments were conducted in Jaboticabal-SP, in a eutrophic red latosol, in the second year of no-tillage system implementation. The IPR 139 cultivar was used in split plot design with three replications, in randomized block. The plots had been composed for three crop systems in the summer season, with maize exclusive, maize intercropped with U. ruziziensis and U. ruziziensis exclusive. The subplots had been constituted for five nitrogen rates (0, 40, 80, 120 and 160 kg ha(-1)), applied as topdressing at V4-4 in irrigated common-bean cultivated in the winter-spring season. The use of U. ruziziensis in crops systems, exclusive or intercropped with maize favors the grass cover crop production sufficiently to total soli surface covered, possibility similar grain yield compared to maize exclusive. The topdressing nitrogen application doesn't affect the common-bean yield in succession to maize and U. ruziziensis intercropped. The increase of nitrogen rates in common-bean in succession to maize exclusive improves the yield, although decreases the agronomic efficiency.

Efeitos de doses e formas de aplicação de reguladores de crescimento em uvas sem sementes, cv. BRS Clara, em região tropical

O objetivo deste trabalho foi avaliar o efeito do uso dos reguladores vegetais, ácido giberélico e tidiazuron, no tamanho de bagas da cultivar BRS Clara em Região Tropical. Os experimentos foram conduzidos em 2006 e 2007, na Estação Experimental de Viticultura Tropical, em Jales-SP, região noroeste do Estado de São Paulo, em plantas da cv. BRS Clara. Foram testadas diferentes concentrações de GA3 aplicadas isoladamente, combinadas com Crop Set ou tidiazuron, em aplicações únicas ou sequênciais (2 e 4 vezes). As avaliações foram feitas por ocasião da maturação das uvas, considerando-se a massa fresca dos cachos, dos engaços e das bagas, determinadas por meio de balança analítica; o comprimento e o diâmetro médio das bagas, utilizando-se de paquímetro; e o teor de sólidos solúveis (SS), por meio de refratômetro manual. Os experimentos foram conduzidos em delineamento experimental de blocos casualizados, representados por uma planta, com 15 repetições, no ano de 2006, e 10 repetições, no ano de 2007. Os dados foram submetidos à análise de variância e, para a comparação das médias dos tratamentos, foi utilizado o teste Skott Nott, ao nível de 5% de probabilidade. Observou-se que o uso dos reguladores promoveu o crescimento das bagas na cultivar BRS Clara em todos os tratamentos, diferindo da testemunha.

Effect of beta 1,3 glucan in stress responses of the pencilfish (Nannostomus trifasciatus) during transport within the rio Negro basin

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The effect of non-antihypertensive doses of angiotensin converting enzyme inhibitor on myocardial necrosis and hypertrophy in young rats with renovascular hypertension

In renovascular hypertensive rats, low doses of angiotensin converting enzyme (ACE) inhibitors have been found to prevent myocardial hypertrophy independent of blood pressure level. This finding would suggest humoral rather than mechanical control of myocyte growth. The aim of this study was to examine the effect of nonantihypertensive doses of ACE inhibitor on myocardial hypertrophy and necrosis in hypertensive rats. Renovascular hypertension (RHT) was induced in four-week-old Wistar rats. Twenty-eight animals were treated for four weeks with three doses of ramipril (0.01, 0.1 or 1. 0 mg/kg/day, which are unable to lower blood pressure. Fourteen animals were not treated (RHT group). A sham operated, age/sex-matched group was used as control (n = 10). Myocardial histology was analysed in 3 microm thick sections of the ventricle stained with either haematoxylin-eosin, reticulin silver stain or Masson's trichrome. There was a significant correlation between systolic blood pressure and left ventricular to body weight ratio in both sets of animals: untreated plus controls and ramipril-treated rats. ACE inhibition prevented myocyte and perivascular necrosis and fibrosis in a dose-dependent manner. We conclude that myocardial hypertrophy in rats with renovascular hypertension is directly related to arterial pressure, and that this relationship is not affected by nonantihypertensive doses of ACE inhibitor. Myocardial necrosis/fibrosis and coronary artery damage induced by angiotensin II are prevented by ACE inhibitor in a dose-dependent manner, despite the presence of arterial hypertension.

Pharmacokinetics of tetracycline in plasma, synovial fluid and milk using single intravenous and single intravenous regional doses in dairy cattle with papillomatous digital dermatitis

The purpose of this study was to compare the pharmacokinetics of tetracycline in plasma, synovial fluid, and milk following either a single systemic intravenous (i.v.) injection or a single i.v. regional antibiosis (IVRA) administration of tetracycline hydrochloride to dairy cattle with papillomatous digital dermatitis (PDD). To this end, plasma and synovial fluid tetracycline concentrations were compared with the minimal inhibitory concentration (MIC) values of the major bacteria, which are known to cause digital diseases and thus assess its efficacy in PDD. Residual tetracycline concentrations in milk from cows treated by both methods were also determined. Twelve Holstein cows with various stages of PDD were randomly assigned to two groups of six animals. Group 1 received a single systemic i.v. injection of 10 mg/kg of tetracycline hydrochloride. Group 2 received 1000 mg of tetracycline hydrochloride by IVRA of the affected limb. Blood, synovial fluid and milk samples were taken prior to tetracycline administration (time 0 control), and then at 22, 45 and 82 min, and 2, 3, 4, 6, 8, 12, 24, 48, 72, 96, and 120 h following drug administration. Tetracycline concentrations were determined by high-performance liquid chromatography. Mean tetracycline plasma and milk concentrations in Group 1 were higher than Group 2. The opposite was observed for synovial fluid concentrations. Group 2 synovial fluid concentrations were higher than the MIC value over 24 h for the bacteria most frequently responsible for claw disease. Compared with i.v. administration, IVRA administration of tetracycline produced very high synovial fluid and low plasma and milk concentrations.

Desempenho agronômico do milho e do trigo em função da inoculação com azospirillum brasilense e doses e fontes de nitrogênio

Pós-graduação em Agronomia - FEIS

Influência da suplementação da ração com diferentes doses de vitamina D sobre a proteína de interação com a tiorredoxina (TXNIP) no coração e suas vias de sinalização

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Manejo da fertilização NK em plantio de eucalyptus urophylla em solo de cerrado

Pós-graduação em Agronomia - FEIS

In vivo evaluation of the antimutagenic and antigenotoxic effects of beta-glucan extracted from Saccharomyces cerevisiae in acute treatment with multiple doses

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Modulation of thyroid hormone receptors, TR alpha and TR beta, by using different doses of triiodothyronine (T3) at different times

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Fonte alternativa de K obtida da produção de KCl a partir da rocha silicática potássica (verdete) na cultura de milho

Para produzir o termopotássio e, até mesmo, o KCl, a rocha silicática potássica (verdete) passa pelo processo de calcinação. Neste processo é gerado um resíduo denominado coproduto que contém em sua composição química 3% a 4% de K2O, Ca, Mg e Si e apresenta baixa solubilidade em água. O presente trabalho objetivou testar a hipótese de que doses de K2O na forma de coproduto fornecem potássio para as plantas de milho em menor quantidade do que as mesmas doses na forma de KCl, inclusive no estudo do efeito residual, e que o potássio extraído do solo pela resina trocadora de íons tem maior correlação com as quantidades de potássio absorvida pela planta de milho do que com o potássio extraído pela solução extratora de Mehlich-1. O experimento foi conduzido em casa de vegetação, onde foram realizados dois cultivos consecutivos de milho em amostras de Neossolo Quartizarênico órtico. O delineamento foi em blocos casualizados com duas fontes de K (KCl e coproduto), três doses de K2O (0, 200 e 400 kg ha-1) e quatro repetições, totalizando 24 unidades experimentais. Foram determinados os teores de potássio extraído da amostra de solo pela solução extratora de Mehlich-1 e resina trocadora de íons, a produção de matéria seca da parte aérea das plantas de milho, os teores e o acumulo de potássio nas plantas após o primeiro e o segundo cultivo. Em dois cultivos consecutivos das plantas de milho, a aplicação de 200 e 400 kg ha-1 de K2O na forma de KCl proporcionou o acumulo de potássio na parte aérea das plantas de 77 e 84% maior do que aplicação dessas mesmas doses de K2O na forma de coproduto, respectivamente. A aplicação de 200 e 400 kg ha-1 de K2O na forma de coproduto proporcionou aumentos no acumulo de potássio da parte aérea das plantas de milho de 66 e 75% em relação ao controle (sem K2O), respectivamente. A recuperação de potássio pelas plantas de milho tratadas com KCl foi de 92% e as plantas...

Efeito da adubação biológica em cana-de-açúcar associada a doses crescentes de fertilização mineral

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)