997 resultados para Pradt, M. de (Dominique Georges Frédéric), 1759-1837.


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Esta dissertação analisa os usos da farinha de mandioca no Estado do Maranhão e Grão-Pará no período de 1722-1759, destacando a farinha como o alimento básico das populações indígenas, repleta de aspectos culturais e simbólicos. Igualmente, analisa como este alimento passou a adquirir importância singular entre os colonizadores portugueses, tornando-se elemento fundamental ao longo do processo de colonização da Coroa portuguesa no extremo norte, enfocando aspectos relevantes acerca da circulação e comercialização da farinha e o papel da £o de obra indígena nas esferas da produção, circulação e desse gênero.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Considering the premise that there are few theoretical reflections in the Portuguese language, concerning the autobiography as a genre, we propose to present a work addressing this issue by discussing the writings of George Gusdorf (1912-2000). One of the most expressive French scholars on this field, alongside Philippe Lejeune and Jean George May, and Starobinsky, Gusdorf stands out for his vast production centered on theoretical issues concerning the writings of the self. The study presented here aims at disseminating Gusdorf writings in Brazil, as well as presenting a critical analysis of the most pertinent issues related to the autobiographical genre, including aspects such as its origins, the blurred boundaries of genre, truth and sincerity, the relations between time and memory, self-knowledge and knowledge of the world.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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This register lists the largest trees of over 80 species identified in Nebraska. The name of the owner and nominator, size and location of each tree follow each listing. Many people across Nebraska have worked hard to make this register as comprehensive and accurate as possible, but the quest to find the largest trees in Nebraska is never over. Champion trees are by nature old, and old trees diminish and die. Larger trees are newly discovered. Thus, this list continually changes as new nominations are submitted.

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Leporinus obtusidens Valenciennes, 1837 and L. elongatus Valenciennes, 1850 are redescribed based on the type specimens, including those of their junior synonyms, and recently collected specimens. Leporinus obtusidens is considered to be widespread, occuring in the river drainages of La Plata, São Francisco, and Parnaíba. Leporinus aguapeiensis Campos, 1945, described from the upper Rio Paraná, and L. silvestrii Boulenger, 1902, described from the Rio Paraguay, are considered junior synonyms of L. obtusidens. Leporinus elongatus is endemic to the Rio Jequitinhonha and Rio Pardo, two eastern Brazilian river basins, and the locality cited for the lectotype, Rio São Fransico, likely to be erroneous. Leporinus crassilabris Borodin, 1929, and L. crassilabris breviceps Borodin, 1929, both described from the Rio Jequitinhonha, are considered junior synynoms of L. elongatus. A new species of Leporinus, endemic to the upper Rio Paraná, very similar and sometimes mistaken with L. obtusidens, is formally described. In addition, comments on Leporinus pachyurus Valenciennes, 1850 and on L. bimaculatus Castelnau, 1855 are provided, and a lectotype for L. bimaculatus is selected.

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Niemann-Pick disease type C (NP-C) is a rare, progressive, irreversible disease leading to disabling neurological manifestations and premature death. The estimated disease incidence is 1:120,000 live births, but this likely represents an underestimate, as the disease may be under-diagnosed due to its highly heterogeneous presentation. NP-C is characterised by visceral, neurological and psychiatric manifestations that are not specific to the disease and that can be found in other conditions. The aim of this review is to provide non-specialists with an expert-based, detailed description of NP-C signs and symptoms, including how they present in patients and how they can be assessed. Early disease detection should rely on seeking a combination of signs and symptoms, rather than isolated findings. Examples of combinations which are strongly suggestive of NP-C include: splenomegaly and vertical supranuclear gaze palsy (VSGP); splenomegaly and clumsiness; splenomegaly and schizophrenia-like psychosis; psychotic symptoms and cognitive decline; and ataxia with dystonia, dysarthria/dysphagia and cognitive decline. VSGP is a hallmark of NP-C and becomes highly specific of the disease when it occurs in combination with other manifestations (e.g. splenomegaly, ataxia). In young infants (<2 years), abnormal saccades may first manifest as slowing and shortening of upward saccades, long before gaze palsy onset. While visceral manifestations tend to predominate during the perinatal and infantile period (2 months–6 years of age), neurological and psychiatric involvement is more prominent during the juvenile/adult period (>6 years of age). Psychosis in NP-C is atypical and variably responsive to treatment. Progressive cognitive decline, which always occurs in patients with NP-C, manifests as memory and executive impairment in juvenile/adult patients. Disease prognosis mainly correlates with the age at onset of the neurological signs, with early-onset forms progressing faster. Therefore, a detailed and descriptive picture of NP-C signs and symptoms may help improve disease detection and early diagnosis, so that therapy with miglustat (Zavesca®), the only available treatment approved to date, can be started as soon as neurological symptoms appear, in order to slow disease progression.