Clinica psicanalítica: o sentimento de solidão e a saúde mental de mulheres casadas

Este trabalho teve como objetivo principal investigar o sentimento de solidão e a saúde mental de mulheres casadas, procurando comparar a maneira de compreender e vivenciar este sentimento em mulheres solteiras e casadas, bem como verificar em que medida este sentimento pode ser mitigado pela presença do outro no casamento (coabitação) e em que condições isto ocorria. Partiu-se da hipótese de que esse sentimento é compartilhado por todas as pessoas, já que o ser humano é uno e individual. Logo, a separação eterna do outro, que se inicia quando o bebê percebe que é diferente da mãe e, assim, um indivíduo único, está associado a uma sensação de solidão que acompanha o ser humano por toda a vida. Desta forma, é muito comum ver pessoas se envolver em relacionamentos para diminuir este sentimento, que se vê intensificado a cada dia em função da superficialidade dos vínculos emocionais. A presença de outrem pode ser aproveitada numa relação interpessoal quando se diminui a intensidade da hostilidade, associada ao sentimento de solidão. O antídoto contra tal sentimento vem do fortalecimento do auto-conhecimento, da autonomia, e da amizade por um companheiro que mostra aceitação incondicional pelo verdadeiro self. Para análise deste sentimento em mulheres casadas, foi realizada uma pesquisa quantitativa e qualitativa com mulheres solteiras e universitárias. A escolha da amostra foi aleatória e por conglomerado, em três estágios. Participaram do estudo 184 mulheres, 38% casadas, 7,6% separadas e 52,7% solteiras. Da pesquisa quantitativa foi possível analisar que a percepção das mulheres sobre a solidão vem, em muitos aspectos, de encontro com a teoria psicanalítica. Pelas respostas encontradas percebeu-se que a grande maioria das participantes tem um baixo sentimento de solidão (58,7%) e 41,3% se classificaram com um escore de alto a médio sentimento de solidão, nestes dois grupos a maioria são de mulheres casadas e separadas, sendo que quanto mais nova a mulher maior a tendência a buscar um relacionamento para fugir da solidão, sendo entre as casadas também que isto ocorre com mais freqüência. A partir destes escores, 18 mulheres foram convidadas a participar de uma entrevista diagnóstica. Destas dezoito, seis mulheres apresentavam alto sentimento de solidão, sendo duas casadas, duas solteiras e duas separadas. Da mesma forma as mulheres com média e baixa solidão. Os resultados encontrados nestas entrevistas foram que todas as mulheres que apresentaram um alto sentimento de solidão demonstram uma adaptação ineficaz perante a vida, enquanto que aquelas que apresentaram médio ou baixo sentimento de solidão dificilmente apresentam adaptação ineficaz. Do grupo de médio sentimento de solidão, três mulheres apresentaram adaptação eficaz, e do grupo de baixo sentimento de solidão apenas uma participante apresentou adaptação ineficaz leve. Com isso concluímos que a solidão, quando em alta medida, além de dolorosa indica uma grande dificuldade do indivíduo em lidar com seus aspectos emocionais e produtivos, necessitando de ajuda psíquica.

CLÍNICA PSICANALÍTICA: O SENTIMENTO DE SOLIDÃO E A SAÚDE MENTAL DE MULHERES CASADAS

Este trabalho teve como objetivo principal investigar o sentimento de solidão e a saúde mental de mulheres casadas, procurando comparar a maneira de compreender e vivenciar este sentimento em mulheres solteiras e casadas, bem como verificar em que medida este sentimento pode ser mitigado pela presença do outro no casamento (coabitação) e em que condições isto ocorria. Partiu-se da hipótese de que esse sentimento é compartilhado por todas as pessoas, já que o ser humano é uno e individual. Logo, a separação eterna do outro, que se inicia quando o bebê percebe que é diferente da mãe e, assim, um indivíduo único, está associado a uma sensação de solidão que acompanha o ser humano por toda a vida. Desta forma, é muito comum ver pessoas se envolver em relacionamentos para diminuir este sentimento, que se vê intensificado a cada dia em função da superficialidade dos vínculos emocionais. A presença de outrem pode ser aproveitada numa relação interpessoal quando se diminui a intensidade da hostilidade, associada ao sentimento de solidão. O antídoto contra tal sentimento vem do fortalecimento do auto-conhecimento, da autonomia, e da amizade por um companheiro que mostra aceitação incondicional pelo verdadeiro self. Para análise deste sentimento em mulheres casadas, foi realizada uma pesquisa quantitativa e qualitativa com mulheres solteiras e universitárias. A escolha da amostra foi aleatória e por conglomerado, em três estágios. Participaram do estudo 184 mulheres, 38% casadas, 7,6% separadas e 52,7% solteiras. Da pesquisa quantitativa foi possível analisar que a percepção das mulheres sobre a solidão vem, em muitos aspectos, de encontro com a teoria psicanalítica. Pelas respostas encontradas percebeu-se que a grande maioria das participantes tem um baixo sentimento de solidão (58,7%) e 41,3% se classificaram com um escore de alto a médio sentimento de solidão, nestes dois grupos a maioria são de mulheres casadas e separadas, sendo que quanto mais nova a mulher maior a tendência a buscar um relacionamento para fugir da solidão, sendo entre as casadas também que isto ocorre com mais freqüência. A partir destes escores, 18 mulheres foram convidadas a participar de uma entrevista diagnóstica. Destas dezoito, seis mulheres apresentavam alto sentimento de solidão, sendo duas casadas, duas solteiras e duas separadas. Da mesma forma as mulheres com média e baixa solidão. Os resultados encontrados nestas entrevistas foram que todas as mulheres que apresentaram um alto sentimento de solidão demonstram uma adaptação ineficaz perante a vida, enquanto que aquelas que apresentaram médio ou baixo sentimento de solidão dificilmente apresentam adaptação ineficaz. Do grupo de médio sentimento de solidão, três mulheres apresentaram adaptação eficaz, e do grupo de baixo sentimento de solidão apenas uma participante apresentou adaptação ineficaz leve. Com isso concluímos que a solidão, quando em alta medida, além de dolorosa indica uma grande dificuldade do indivíduo em lidar com seus aspectos emocionais e produtivos, necessitando de ajuda psíquica.

CLÍNICA PSICANALÍTICA: O SENTIMENTO DE SOLIDÃO E A SAÚDE MENTAL DE MULHERES CASADAS

Este trabalho teve como objetivo principal investigar o sentimento de solidão e a saúde mental de mulheres casadas, procurando comparar a maneira de compreender e vivenciar este sentimento em mulheres solteiras e casadas, bem como verificar em que medida este sentimento pode ser mitigado pela presença do outro no casamento (coabitação) e em que condições isto ocorria. Partiu-se da hipótese de que esse sentimento é compartilhado por todas as pessoas, já que o ser humano é uno e individual. Logo, a separação eterna do outro, que se inicia quando o bebê percebe que é diferente da mãe e, assim, um indivíduo único, está associado a uma sensação de solidão que acompanha o ser humano por toda a vida. Desta forma, é muito comum ver pessoas se envolver em relacionamentos para diminuir este sentimento, que se vê intensificado a cada dia em função da superficialidade dos vínculos emocionais. A presença de outrem pode ser aproveitada numa relação interpessoal quando se diminui a intensidade da hostilidade, associada ao sentimento de solidão. O antídoto contra tal sentimento vem do fortalecimento do auto-conhecimento, da autonomia, e da amizade por um companheiro que mostra aceitação incondicional pelo verdadeiro self. Para análise deste sentimento em mulheres casadas, foi realizada uma pesquisa quantitativa e qualitativa com mulheres solteiras e universitárias. A escolha da amostra foi aleatória e por conglomerado, em três estágios. Participaram do estudo 184 mulheres, 38% casadas, 7,6% separadas e 52,7% solteiras. Da pesquisa quantitativa foi possível analisar que a percepção das mulheres sobre a solidão vem, em muitos aspectos, de encontro com a teoria psicanalítica. Pelas respostas encontradas percebeu-se que a grande maioria das participantes tem um baixo sentimento de solidão (58,7%) e 41,3% se classificaram com um escore de alto a médio sentimento de solidão, nestes dois grupos a maioria são de mulheres casadas e separadas, sendo que quanto mais nova a mulher maior a tendência a buscar um relacionamento para fugir da solidão, sendo entre as casadas também que isto ocorre com mais freqüência. A partir destes escores, 18 mulheres foram convidadas a participar de uma entrevista diagnóstica. Destas dezoito, seis mulheres apresentavam alto sentimento de solidão, sendo duas casadas, duas solteiras e duas separadas. Da mesma forma as mulheres com média e baixa solidão. Os resultados encontrados nestas entrevistas foram que todas as mulheres que apresentaram um alto sentimento de solidão demonstram uma adaptação ineficaz perante a vida, enquanto que aquelas que apresentaram médio ou baixo sentimento de solidão dificilmente apresentam adaptação ineficaz. Do grupo de médio sentimento de solidão, três mulheres apresentaram adaptação eficaz, e do grupo de baixo sentimento de solidão apenas uma participante apresentou adaptação ineficaz leve. Com isso concluímos que a solidão, quando em alta medida, além de dolorosa indica uma grande dificuldade do indivíduo em lidar com seus aspectos emocionais e produtivos, necessitando de ajuda psíquica.

Expression of a gene encoding a 16.9-kDa heat-shock protein, Oshsp16.9, in Escherichia coli enhances thermotolerance

A gene encoding the rice 16.9-kDa class I low-molecular-mass (LMM) heat-shock protein (HSP), Oshsp16.9, was introduced into Escherichia coli using the pGEX-2T expression vector to analyze the possible function of this LMM HSP under heat stress. It is known that E. coli does not normally produce class I LMM HSPs. We compared the survivability of E. coli XL1-Blue cells transformed with a recombinant plasmid containing a glutathione S-transferase (GST)–Oshsp16.9 fusion protein (pGST-FL cells) with the control E. coli cells transformed with the pGEX-2T vector (pGST cells) under heat-shock (HS) after isopropyl β-d-thiogalactopyranoside induction. The pGST-FL cells demonstrated thermotolerance at 47.5°C, a treatment that was lethal to the pGST cells. When the cell lysates from these two E. coli transformants were heated at 55°C, the amount of protein denatured in the pGST-FL cells was 50% less than that of the pGST cells. Similar results as pGST-FL cells were obtained in pGST-N78 cells (cells produced a fusion protein with only the N-terminal 78 aa in the Oshsp16.9 portion) but not in pGST-C108 cells (cells produced a fusion protein with C-terminal 108 aa in the Oshsp16.9 portion). The acquired thermotolerant pGST-FL cells synthesized three types of HSPs, including the 76-, 73-, and 64-kDa proteins according to their abundance at a lethal temperature of 47.5°C. This finding indicates that a plant class I LMM HSP, when effectively expressed in transformed prokaryotic cells that do not normally synthesize this class of LMM HSPs, may directly or indirectly increase thermotolerance.

Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.

The adenovirus type 2/5 E1A proteins transform primary baby rat kidney (BRK) cells in cooperation with the activated Ras (T24 ras) oncoprotein. The N-terminal half of E1A (exon 1) is essential for this transformation activity. While the C-terminal half of E1A (exon 2) is dispensable, a region located between residues 225 and 238 of the 243R E1A protein negatively modulates in vitro T24 ras cooperative transformation as well as the tumorigenic potential of E1A/T24 ras-transformed cells. The same C-terminal domain is also required for binding of a cellular 48-kDa phosphoprotein, C-terminal binding protein (CtBP). We have cloned the cDNA for CtBP via yeast two-hybrid interaction cloning. The cDNA encodes a 439-amino acid (48 kDa) protein that specifically interacts with exon 2 in yeast two-hybrid, in vitro protein binding, and in vivo coimmunoprecipitation analyses. This protein requires residues 225-238 of the 243R E1A protein for interaction. The predicted protein sequence of the isolated cDNA is identical to amino acid sequences obtained from peptides prepared from biochemically purified CtBP. Fine mapping of the CtBP-binding domain revealed that a 6-amino acid motif highly conserved among the E1A proteins of various human and animal adenoviruses is required for this interaction. These results suggest that interaction of CtBP with the E1A proteins may play a critical role in adenovirus replication and oncogenic transformation.

Title page of scrapbook with Harvard University Library bookplate

This bookplate indicates that the scrapbook was donated to the library by Edward L. Pierce in June 1893; it is not known who assembled the scrapbook, although it was presumanly either Pierce or the younger Sumner.

Unity stronger than divisions. Ukraine's internal diversity. OSW Point of View Number 40, March 2014

Ukraine is deeply divided internally, although as a result of the changes that have taken place since its independence, the country’s internal divisions now have less and less to do with territorial divides, and the split into historical ‘sub-Ukraines’ has become less pronounced, especially for the younger generation. Ukraine is not a country of two competing regional identities, one in the west, the other in the east. The western identity, in which the unity of Ukraine is a key value, coexists with the multiple and diverse local patriotisms of the different regions in the east and the south of the country. The present protest movement has consolidated the country’s sense of unity. Its opponents have also been championing the indivisibility of Ukraine, even while they demanded a thorough decentralisation of the country, which was often mistaken for separatism. Russia has been stirring up separatist tendencies in Ukraine, but with little success. Crimea is an exception here, because in most respects it has remained unaffected by the dynamics of the social processes transforming mainland Ukraine – separatist tendencies are indeed deeply rooted in the peninsula.

Europe cannot afford people in bad health - Economics of health and care as a guide for investments. EPC Commentary, 4 July 2016

It is widely accepted that a new way of looking at Europe’s health sector is necessary if we are to maintain universal health coverage. Financial resources are limited, and the sustainability of Europe’s health systems is under threat. Economic growth is slow, health expenditures outpace GDP growth, public budgets are under strain and demographics – with a growing aging population – are putting pressure on the younger tax-paying generations. In an effort to ensure the sustainability of Europe’s health systems, reforms, underpinned by a new understanding of the economic value of health for individuals and society is needed.

Thrombolysis in Patients Aged over 80 Years Is Equally Effective and Safe

BACKGROUND: Despite stroke's high prevalence in the elderly, intravenous thrombolysis is licensed in Europe only for patients younger than 80 years old. We aimed to compare the functional outcomes and complication rates in patients older versus younger than 80 years old treated with intravenous thrombolysis. METHODS: A retrospective observational study of patients who received intravenous thrombolysis in a stroke unit between January 1, 2009, and June 30, 2012, was conducted. Variables were compared between 2 subgroups (≤80 and >80 years). RESULTS: Overall, 512 patients underwent intravenous thrombolysis, of which 13.1% were over 80 years. The mean age was 65.4 years in the younger subgroup and 82.9 years in the older subgroup. Prior independence rates did not differ between the subgroups. Prevalence of atrial fibrillation and cardioembolic stroke was higher in the older subgroup (P = .004 and .026). Only 3% of the elderly with atrial fibrillation were taking oral anticoagulants. Symptoms-to-needle time was lower in the older subgroup (P = .048). Stroke severity was higher in patients over 80 years (P = .026). There was significant improvement in the National Institutes of Health Stroke Scale score 7 days after intravenous thrombolysis (P < .001) in both subgroups. The proportion of patients with 3 months' favorable outcome and independence, hemorrhagic transformation, and mortality rates were similar in both subgroups. CONCLUSIONS: Elderly patients' benefits and outcomes from intravenous thrombolysis treatment were identical to the younger subgroup without excess hemorrhagic transformation or mortality. These results favor the use of intravenous thrombolysis in patients over 80 years.

Sporocarp succession of soil-inhabiting macrofungi in an autochthonous subalpine Norway spruce forest of Switzerland

Sporocarps of macrofungi have been recorded in two neighbouring pure stands of Norway spruce (Picea abies) of different age due to a wind-throw in the subalpine zone of the Alps. The still open young stand of 30 years with trees up to 6 m displayed 80 species, the mature closed forest stand 90 species. Species richness of mycorrhizal fungi is higher in the mature stand than in the younger one, however, with an almost doubled sporocarp production in the latter one. The opposite is found with saprotrophic fungi. Several fungi appeared only in one forest type confirming the concept of early stage versus late stage fungi. Wind-throws as irregular events in subalpine forests, create gaps and add considerably to the species diversity of macrofungi.

Mineral-magnetic record of Late Quaternary climatic changes in a high Alpine lake

The magnetic properties of a sediment core from a high altitude lake in the Swiss Alps were compared with palynological and geochemical data to link climatic and mineral magnetic variations. According to pollen data, the sediments extend from the present to the Younger Dryas, i.e., they cover more than 10,000 years of environmental change in the Alps. The major change in magnetic properties corresponds to the climatic warming of the early Holocene. High-coercivity magnetic minerals that characterize the Late Glacial period almost disappeared during the Holocene and the concentration of ferrimagnetic minerals increased sharply. The contribution of superparamagnetic grains also decreased in the Holocene sediments. Similar variations in {SP} content and coercivity, of smaller magnitude, are found in the Holocene and are interpreted to represent minor climatic variations. Comparison with the historical record of the last 1000 years confirms this interpretation. The magnetic mineralogy, the superparamagnetic contents, and the {IRM} intensity in the coarse-grained, Late Glacial sediments are similar to those measured in the catchment bedrock. This indicates a detrital origin. The different properties and the higher concentration of magnetic minerals in the Holocene sediments are due to authigenic phases. Magnetic properties provide a high resolution record of climatic change. They are sensitive even to small variations that are not recorded in the pollen or {LOI} data. Magnetic parameters show fine-scale variation and constitute a valuable supplement to conventional climatic indicators.

Geochemistry of basalts from ODP Leg 49, North Atlantic Ocean

The geochemistry of basalts recovered from seven sites in the North Atlantic is described with particular reference to minor elements. Three sites (407, 408, and 409) along the same mantle flow line, transverse to the Reykjanes Ridge at about 63°N, provide information on the composition of basalts erupted over a 34-m.y. interval between 2.3 and 36 m.y. ago. At Site 410, at 45°N, penetration into 10 m.y.-old crust west of the ridge axis permits comparisons with young basalts dredged from the median valley at 45°N. Three sites in the FAMOUS area at about 36°N provided material from very young (1 m.y.) basaltic crust (Site 411), and material to test the geochemical coherence of basalts of different ages (1.5 and 3.5 m.y.) on either side of a fracture zone (Sites 412 and 413). These sites complement earlier data from dredged and drilled sites (Leg 37) in the FAMOUS area. At Site 407, four geochemically distinct basalt units occur, with different normative and rare-earth element (REE) characteristics, and there is a clear correlation with magnetic stratigraphy. Yet there is a remarkable consistency in incompatible element ratios between these units, indicating derivation from an essentially similar mantle source. The basalts from the younger sites, 408 and 409, show a similar range of normative and REE variation, but incompatible element ratios are identical to those at Site 407, indicating that basalts at all three sites were produced from a mantle source which was geochemically relatively uniform. Rare-earth differences between the basalts can be interpreted in terms of variations in the degree and depth of partial melting causing HREE (+Y) retention in the source, although there may be some inter-site differences with respect to REE. A similar picture is presented at 45°N. Apparently a range of tholeiitic, transitional, and alkalic basalts were being erupted 10 m.y. ago, which have almost identical geochemical characteristics to those recently erupted in the median valley at 45°N. Incompatible element ratios are markedly different from those recorded at the Reykjanes Ridge. Basalts recovered from the FAMOUS sites are geochemically similar to previous samples recovered from the FAMOUS area, and their incompatible element ratios are similar, but not identical, to those at 45°N. However, total trace element levels are consistently lower than in 45°N basalts, which might imply smaller degrees of partial melting and/or greater depths of magma generation at 45°N, or higher trace element levels in the mantle source at 45°N. Few of the basalts recovered on Leg 49 have the geochemical characteristics of typical "MORB" (e.g., Nazca Plate, Leg 34). The data strongly support models invoking geochemical inhomogeneity in the source regions of basalts produced at the Mid-Atlantic Ridge. However, the data also introduce an additional time factor into such models and demonstrate the uniformity of the mantle source at a particular ridge sector (over periods in excess of 30 m.y.), while emphasizing the marked differences along the ridge. Mixing models invoking "depleted" and "enriched" mantle sources would seem to be inadequate to account for the observed variations.

Sea-surface temperature reconstruction for sediment core GeoB1023-5

Sediment core GeoB 1023-5 from the eastern South Atlantic was investigated at high temporal resolution for variations of sea-surface temperature (SST) during the past 22 kyr, using the alkenone (UK'37) method. SSTs increased by 3.5°C from about 18°C during the Last Ice Age (21±2 cal kyr BP) to about 21.5°C at 14.5 cal kyr BP. This warming trend associated with the deglaciation phase was followed by a cooling event with lowest SSTs near 20°C, persisting for about 1000 years between 13 and 12 cal kyr BP. The SSTs then continued to increase to about 22.5°C at the Holocene climatic optimum at 7 cal kyr BP, and decreased again during the Late Holocene to a core-top value of 19.8°C that is comparable to modern annual mean SST values. When compared with alkenone SST records from the eastern North Atlantic, our SST record indicates continuous warming throughout the deglaciation phase in the Benguela Current, while its northern counterpart, the Canary Current, experienced prominent cooling during 'Heinrich Event 1' (H1). On the other hand, for the time period corresponding to the 'Younger Dryas' (YD) cooling event, the Benguela SST record exhibits a cold-temperature interval that corresponds to that observed in the eastern North Atlantic SST records. This observation suggests that interhemispheric climate response in Atlantic eastern boundary current systems was different with respect to the two abrupt climate events associated with Termination I. For the H1, the eastern South Atlantic SST record strongly supports the hypothesis that an 'anti-phase' thermal behavior in South Atlantic surface waters was forced by the slowdown of the North Atlantic Deep Water formation during cold spells in the North Atlantic. In contrast, the abrupt cooling in the eastern South Atlantic coincident with the YD period was probably induced by more vigorous global atmospheric circulation, enhancing the upwelling intensity in both eastern boundary current systems. This atmospheric control may have overridden any effect caused by changes in thermohaline circulation on the South Atlantic SSTs during the YD, which leads to the assumption that the thermohaline circulation was already much closer to its interglacial mode during the YD than during the H1.

(Table 2) Trace metal concentrations in ODP Hole 169-1033B

We measured the concentrations of redox-sensitive trace metals (Mn, V, Mo, U, Cd and Re) in sediments from ODP Leg 169S Hole 1033B in Saanich Inlet, British Columbia, to determine changes in redox conditions associated with the onset of laminated sediments at ~12.5 kyr. The most striking result is a large peak in authigenic Re along with detrital levels of Mo at the glacial terrigenous clay-diatomaceous sediment transition. In contrast, the underlying glacial terrigenous clay, which extends throughout the bottom section of the core, is chemically similar to detrital concentrations, either Cowichan River particulates or average shale values. These data suggest a period of oxic bottom waters but reducing pore-waters. This could be due to the dramatic transformation of Saanich Inlet during the late deglaciation from an open bay to an inlet, which restricted circulation and slowed bottom water oxygen renewal. A peak and gradual increase in authigenic Mn in younger sediments subsequent to the Re peak suggests that increasingly oxic conditions followed the authigenic enrichment in Re. These conditions could be connected to the Younger Dryas cooling period, which was coincident with an increase in well oxygenated upwelled waters on the west coast of North America that form the bottom waters of Saanich Inlet. Metal concentrations in a gray clay bed (~11 kyr) are similar to their concentrations in the glacial terrigenous clay, implying that they have a common source. Authigenic enrichments of Re with little authigenic Mo and Cd suggest that before the deposition of this bed, bottom waters were oxic and pore-water oxygen was consumed in the top centimeter or less. Laminations above the clay layer suggest anoxic conditions, which are also indicated by higher authigenic Mo and Cd and slightly lower Re/Mo ratios in these sediments. The basin remained mostly anoxic after the gray clay was emplaced, as seen by continuous authigenic enrichment of the redox-sensitive trace metals. These results are consistent with increased stratification of the water column, brought about by an influx of fresh water to the basin by a large flood.

Pollen profile from sediment core KB1, Holzminden, Northern Germany

The Nachtigall clay pit near Holzminden, northern Germany, is located in a subrosional basin filled with 43 m of interglacial, interstadial and stadial deposits adjacent to the Weser River. The succession separates the Older Middle Terrace from the Younger Middle Terrace of the Weser River. Nachtigall core KB1 (1998) mainly contains silt and clay with intercalated peat layers. The layers of fen peat and intercalated humic silt are between 36 and 22.5 m depth. According to palynological studies, the peat layers and some humic silts were deposited during interglacial and interstadial periods marked by forest vegetation, termed Nachtigall 1 and Nachtigall 2. They are subdivided by a stadial, termed Albaxen. The peat of Nachtigall 1 is interrupted twice by silt and clay strata (Allochthonous Unit I, II) which are reworked sediments of older glacial periods, possibly of late Elsterian or early Holsteinian age. The palynological sequences of Nachtigall and Göttingen/Ottostrasse show the same pattern. Moreover, the contemporaneous pollen profiles of Nachtigall and Göttingen/Ottostrasse can be compared with the Velay pollen sequence (France). The Nachtigall core section 36-26.02 m corresponds to Bouchet 2 - Bonnefond - Bouchet 3 in Velay. The profiles of Velay and Nachtigall are independently correlated to the MIS-timescale and correspond to MIS 7c, 7b, and 7a. TIMS 230Th/U-dating shows ages ranging from 227 + 9/-8 to 201 + 15/-13 ka, which are in good agreement with the inferred MIS 7 age.