901 resultados para Fracturas dos Ossos
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The pre-slaughter moment begins with the animal´s loading on the farm and ends up in its drain. It is a period in which the animal is under physical stress caused by hunger, thirst, fatigue, injuries, and extremes of temperature and psychological stress, due to restraint, handling, innovation and fear. Stress and inappropriate handling bring bad consequences for the final product´s quality, requiring better handling conditions, facilities and equipment. Examples of consequences of mishandling: meat with abnormal color, DFD meat (dark, firm and dry), reduced product´s shelf life, bruises and broken bones in carcasses. The operators should be trained and oriented on the basic principles of biology, behavior and management of cattle. At every step of the pre-slaughter moment, the animals should be handled calmly and quietly to avoid excitement and stress. Operators should avoid shouting, whistling or any noise since cattle have very sensitive ears and can become stressed. If the animals refuse to move, the cause of the problem should be determined
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A busca pela identificação de fatores que possam apontar o diagnóstico, a resposta terapêutica e sobrevida dos pacientes portadores de neoplasias ósseas tem sido incessante. Poderá ser de grande valia na escolha da proposta terapêutica presumir a agressividade tumoral, capacidade de invasão tecidual, propensão ao desenvolvimento de metástases e resposta ao tratamento. As neoplasias ósseas constituem um grupo heterogêneo de tumores, considerando-se os sítios anatômicos e a etiologia. Existe uma grande dificuldade para se estabelecer o prognóstico nestas patologias. Estudos citogenéticos possibilitam um melhor conhecimento antecipado dessas doenças. Embora fatores ambientais e dietéticos contribuam para a etiologia do câncer, as neoplasias se originam de um processo de múltiplos passos envolvendo alterações de genes e seleção clonal da progênie variante. Estas mutações ocorrem em classes de genes reguladores da proliferação celular como os oncogenes, genes supressores de tumor, fatores de crescimento, vias de sinalização e genes de reparo de DNA. Este projeto tem por objetivo detectar e descrever alterações cromossômicas consistentes e recorrentes através da utilização da citogenética clássica e o seu envolvimento no prognóstico em neoplasias ósseas, de pacientes do Hospital das Clínicas da Faculdade de Medicina de Botucatu, UNESP. Os conhecimentos sobre a biologia molecular melhoram o entendimento sobre os múltiplos aspectos da carcinogênese. Entretanto, embora, as perspectivas permaneçam, não houve até agora benefícios significativos em termos de prevenção, diagnóstico tratamento e seguimento dos pacientes com lesões ósseas. Este projeto visa estudos na tentativa de contribuir para um melhor entendimento e, por conseqüência, gerar dados para posteriores empregos em terapias mais eficazes para melhorar as taxas de sobrevida e beneficiar maior número de pacientes com neoplasias ósseas
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As mudanças demográficas decorrentes do envelhecimento populacional têm contribuído substancialmente para o aumento de doenças crônicas não transmissíveis relacionadas à idade, dentre elas está a osteoporose, considerada um dos principais problemas de saúde pública, por sua prevalência crescente e pela associação a fraturas em diversas áreas do corpo, com graves repercussões clínicas e sociais. Com isso vem se buscando cada vez mais alternativas de exercício físico válidas para o combate e prevenção a estas doenças ósseas. Como possível alternativa têm se estudado os efeitos e benefícios dos treinamentos realizados em Plataformas Vibratórias, equipamento que através de baixa amplitude e alta freqüência pode vir a influenciar positivamente nas capacidades físicas. Portanto, devido à escassez de informações acerca dos efeitos do exercício na plataforma vibratória sobre a microarquitetura dos ossos em indivíduos idosos e já acometidos pela osteoporose, o objetivo deste estudo foi, com um modelo animal, descrever através de imagens de Microscopia Eletrônica de Varredura (MEV), a reação do tecido ósseo de ratas idosas ovariectomizadas ao exercício em Plataforma Vibratória. Para execução deste estudo foram utilizadas 20 ratas Wistar (Rattus Norvegicus Albinus Wistar), separadas em 4 grupos: Sedentário Controle (S), Sedentário Ovariectomizado (SO), Treinado Controle (T) e Treinado Ovariectomizado (TO). Como protocolo de treinamento a plataforma vibratória foi regulada com freqüência de 35 Hz e amplitude baixa (1 a 2 mm) e consistiu de uma fase de adaptação ao exercício e à vibração e após este período uma fase de treinamento. Para análise a região do osso selecionada foi o terço proximal da diáfise do fêmur. Como resultado, obtivemos que para o grupo SO a indução à osteoporose foi positiva quando comparada ao grupo S, que ...(Resumo completo, clicar acesso eletrônico abaixo)
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Articular cartilage is the structure that coats the bone ends in regions where two bones are articulated, allowing movement. It has inefficient intrinsic and extrinsic mechanisms of repair, usually resulting in fibrocartilage formation after injury. Such repair have lower strength, stiffness and usability features when compared to hyaline cartilage. The mesenchymal stem cells have the potential to regenerate tissue without the production of scar, and because of this feature it is well studied. But to have its maximum chondrogenic potential, it is necessary to use scaffolds and growth factors. Biomaterials play the role of scaffold for the cells allowing them to become attached, grow and produce extracellular matrix, leading to formation of repair with hyaline cartilage. In this sense, the purpose of this study is to provide information on the various studies using cell therapy and / or biomaterials to produce hyaline cartilage
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Pós-graduação em Ciência Animal - FMVA
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Abstract : The objective of this study was to evaluate quantitatively and to describe qualitatively the process of bone repair in the interface of receptor bed and graft autogenous bone block with or without a e-PTFE membrane, in osteopenia induced rats. To this end, we used forty-eight Wistar rats weighing about 300g, in which, with the aid of 4.1 mm trephine a graft was removed from the parietal bone and fixed to the surface of the left mandibular ramus. The animals were randomly divided into four experimental groups: Group 1 (n=12): SHAM operated and autogenous bone graft only; Group 2 (n=12): SHAM and autogenous bone graft covered by e-PTFE membrane; Group 3 (n=12): ovariectomized rats (OVX) and autogenous bone graft only; Group 4 (n=12): OVX and autogenous bone graft covered by e-PTFE membrane. The animals in each group were sacrificed at three time periods: 21, 45 and 60 days, each time with 4 animals per group. The specimens were decalcified and included, the sections were stained with HE and subjected to histological and histomorphometric analysis in light microscopy. The results of the ANOVA showed that the variables on the condition (OVZ and SHAM), and the time (21, 45 and 60 days) were statistically significant, and can be established with the Tukey test (5%) that the period 21-day differs significantly from the periods of 45 and 60 days, which did not differ among themselves. The descriptive histological analysis showed integration of the graft in all animals. It was concluded that the initial integration of the graft bed was negatively affected in the presence of induced osteopenia, and that the use or not of a e-PTFE membrane did not interfere in the process of integration
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Titanium and its alloys has been widely used as materials for metallic biomaterials implants are usually employed to restore the hard tissue function, being used for artificial joints and bones, synthetic plates, crowns, dental implants and screws . Objective of this work was the surface modification of Ti-alloy 25Ta from biomimetic surface treatment of employment and deposition of polymer by electrospinning. The league was obtained from the fusion of the pure elements in the arc furnace with controlled atmosphere. The ingots were subjected to heat treatment, cold forged and sectioned discs with 13 mm diameter and 3 mm thick. Two surface treatments was evaluated, biomimetic and electrospinning with PCL fiber. The biomimetic treatment was performed involving alkaline treatment for three molarities 1.5M, 3M and 5M with immersion in SBF. The electrospinning was performed using PCL polymer alloy surface after the alkali treatment Ti25Ta 1M. For this group the polymer coated surfaces were immersed in calcium phosphate containing solution for immobilization of apatite. The results were compared with previous studies using surface treatment group to verify hydroxyapatite formation on the sample surface and it is concluded that the best condition is biomimetic treatment with 5M alkali treatment and heat treatment at 80 ° C for 72 hours
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Imunomarcação da OPG e RANKL no reparo ósseo após a cirurgia de elevação do seio maxilar com Bio-Oss
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Odontologia - FOA
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Ciência Animal - FMVA
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The knowledge of the facial growth trend is very important in orthodontic treatment. A lateral headfilm is recommended in all young patients undergoing a preorthodontic guidance program to anticipate the best time to begin any mechanical procedures and the possibilities to determine the type of facial growth trend. In type A it will be observed that the middle and lower face are growing forward and downward in unison, with no change in ANB angle. Type B growth trends reveals that growth is downward and forward, with the middle face growing forward more rapidly than the lower and in type C the lower face is growing downward and forward more rapidly than the middle face revealing a decrease in the size of the ANB angle.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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The aim of the present study was to analyze the etiology, type and treatment employed in the orbito-zygomatic fractures (OZ). Also, postoperative complications are described and correlated with the type of treatment used. Fifty patients with OZ fractures were evaluated. Orbital fractures in which the zygomatic bone was not involved were excluded. Epidemiologic data and characteristics of treatment such as the type of material used for osteosynthesis, number of anatomical sites on which rigid internal fixation (RIF) was applied, surgical approaches and associated complications were recorded. The main causes of trauma were motorcycle and bicycle accidents, constituting 52% of the sample. The osteosynthesis system used was the 2.0 mm, except in four patients in whom the 1.5mm system was used for fixation at the infra-orbital rim. A total of 18% of the patients required reconstruction of the internal orbit and in all cases titanium mesh was used. 46% of the patients received RIF in three anatomical sites, most in the fronto-zygomatic suture, infra-orbital rim and zygomatic-maxillary buttress. The most frequent complication was paresthesia of the infra-orbital nerve (34 patients, 68%). Other findings were also discussed with the intent of better understanding the treatment of the OZ fractures.