Efficacy of a Nasal Spray from Citrus limon and Cydonia oblonga for the Treatment of Hay Fever Symptoms - A Randomized, Placebo Controlled Cross-Over Study

Nasal spray from lemon and quince (LQNS) is used to treat hay fever symptoms and has been shown to inhibit histamine release from mast cells in vitro. Forty-three patients with grass pollen allergy (GPA) were randomized to be treated either with placebo or LQNS for one week, respectively, in a cross-over study. At baseline and after the respective treatments patients were provoked with grass pollen allergen. Outcome parameters were nasal flow measured with rhinomanometry (primary), a nasal symptom score, histamine in the nasal mucus and tolerability. In the per protocol population absolute inspiratory nasal flow 10 and 20 min after provocation was higher with LQNS compared to placebo (-37 ± 87 mL/s; p = 0.027 and -44 ± 85 mL/s; p = 0.022). The nasal symptom score showed a trend (3.3 ± 1.8 in the placebo and 2.8 ± 1.5 in the LQNS group; p = 0.070) in favor of LQNS; the histamine concentration was not significantly different between the groups. Tolerability of both, LQNS and placebo, was rated as very good. LQNS seems to have an anti-allergic effect in patients with GPA. Copyright © 2016 John Wiley & Sons, Ltd.

Sediment constituents and quartz in the sand-sized fraction, West Florida slope and Mississippi Fan sediments

The interval between 488.2 and 513.7 m below seafloor at Deep Sea Drilling Project (DSDP) Site 615 is interpreted as a single carbonate gravity-flow deposit. The deposit has characteristics of both a debris flow and a high-density turbidity current. Comparison of the sedimentary constituents in 15 samples from this site with samples from 26 core tops from the upper West Florida continental slope and eastern Mississippi Fan shows many similarities. Shallow-water indicators, such as mollusk and echinoid fragments, occur in both suites of samples. The West Florida continental margin, therefore, is a potential provenance area. The Yucatan slope is also a possible source, but data from it are limited. The recognition of carbonate gravity-flow deposits intercalated within the Mississippi Fan refines our understanding of Pleistocene sedimentation within the Gulf basin. Deposition in the deep Gulf is dominated by the construction of the Mississippi Fan. However, this marine terrigenous depocenter is located between two large carbonate depocenters, the West Florida continental margin on the east and the Yucatan peninsula on the southwest. Periodically, the carbonate slope in these two regions fails, injecting carbonate gravity flows into the accreting terrigenous deep-sea fan.

Las necesidades de los ancianos hispanos : audiencia ante el Comité Selecto sobre la Vejez, Cámara de Representantes, 95 Congreso, segunda sesión, marzo 28, 1978, Miami, Florida = Needs of the Hispanic elderly : hearing before the Select Committee on Aging, House of Representatives, Ninety-fifth Congress, second session, March 28, 1978, Miami, Fla.

"Comm. pub. no. 95-152."

Congreso de la Florida, julio 18 y 19 de 1920 : sección mutualismo y cooperación, discursos y conferencias, conclusiones y votos del Congreso /

Mode of access: Internet.