Exploration of the visual system : Part 2. In vivo analysis methods : virtual-reality optomotor system, fundus examination and fluorescent angiography

The mouse has emerged as an animal model for many diseases. At IRO, we have used this animal to understand the development of many eye diseases and treatment of some of them. Precise evaluation of vision is a prerequisite for both these approaches. In this unit we describe three ways to measure vision: testing the optokinetic response, and evaluating the fundus by direct observation and by fluorescent angiography.

Sensitivity of feature-based analysis methods of storm tracks to the form of background field removal

For the tracking of extrema associated with weather systems to be applied to a broad range of fields it is necessary to remove a background field that represents the slowly varying, large spatial scales. The sensitivity of the tracking analysis to the form of background field removed is explored for the Northern Hemisphere winter storm tracks for three contrasting fields from an integration of the U. K. Met Office's (UKMO) Hadley Centre Climate Model (HadAM3). Several methods are explored for the removal of a background field from the simple subtraction of the climatology, to the more sophisticated removal of the planetary scales. Two temporal filters are also considered in the form of a 2-6-day Lanczos filter and a 20-day high-pass Fourier filter. The analysis indicates that the simple subtraction of the climatology tends to change the nature of the systems to the extent that there is a redistribution of the systems relative to the climatological background resulting in very similar statistical distributions for both positive and negative anomalies. The optimal planetary wave filter removes total wavenumbers less than or equal to a number in the range 5-7, resulting in distributions more easily related to particular types of weather system. For the temporal filters the 2-6-day bandpass filter is found to have a detrimental impact on the individual weather systems, resulting in the storm tracks having a weak waveguide type of behavior. The 20-day high-pass temporal filter is less aggressive than the 2-6-day filter and produces results falling between those of the climatological and 2-6-day filters.

Assessment of embodied energy analysis methods for the Australian construction industry

Environmental assessment of buildings typically focuses on operational energy consumption in an attempt to minimise building energy consumption. Whilst the operation of Australian buildings accounts for around 20% of total energy consumption nationally, the energy embodied in these buildings represents up to 20 times their annual operational energy. Many previous studies, now shown to be incomplete in system boundary or unreliable, have provided much lower values for the embodied energy of buildings and their products. Many of these studies have used traditional embodied energy analysis methods, such as process analysis and input-output (1-0) analysis. More recently, hybrid embodied energy analysis methods have been developed, combining these two traditional methods. These hybrid methods need to be compared and validated, as these too have been considered to have several limitations. This paper aims to evaluate a recently developed hybrid method for the embodied energy analysis of the Australian construction industry, relative to traditional methods. Recent improvements to this hybrid method include the use of more recent 1-0 data and th.fl inclusion of capital energy data. These significant systemic changes mean that a previous assessment of the methods needs to be reviewed. It was found that the incompleteness associated with process analysis has increased from 49% to 87%. These findings suggest that current best-practice methods of embodied energy analysis are sufficiently accurate for most typical applications. This finding is strengthened by recent improvements to the 1-0 model.

Stress analysis of compression of aluminium with rotating tools

Compression tests carried out on aluminium specimens showed that when the die was rotated the compression load dropped. A slab method is employed to examine this process. The load reduction is explained by the deviation of friction vector due to the relative circumferential movement between the die and the material. This mechanism is incorporated into a theoretical model and an expression is derived for compression pressure. Analytical solutions established compare favourably with experimental results. It is also shown that there is a limitation to the load reduction: the compressive load can never be lower than 70 percent of the yield limit.

Three dimensional stability charts for slopes based on limit analysis methods

This paper uses finite element upper and lower bound limit analysis to produce chart solutions for three-dimensional (3D) natural slopes for both short- and long-term stability. The presented chart solutions are convenient tools that can be used for preliminary design purposes. The rigorous limit analysis results in this paper were found to bracket the true factor of safety within ±10% or better, which can be used as a benchmark for the solutions from other methods. The depth of the slip surfaces is observed to be generally shallow for most analyzed cases, particularly for the long-term slope stability problem. In addition, it was found that using a two-dimensional (2D) analysis may lead to significant differences in estimating safety factors, which can differ by 2%–60% depending on the slope geometry and soil properties. Therefore, great care and judgement are required when applying 2D analyses to 3D slope problems.