900 resultados para Y Receptor
Resumo:
Fil: Moran, Julio César. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.
Resumo:
Fil: Moran, Julio César. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.
Resumo:
La prolífica narrativa de César Aira ha despertado controversia entre sus lectores porque se caracteriza por una tensión paradójica entre, por un lado, una poética culta y un estilo hiperliterario, y por otro, una recurrencia de elementos massmediáticos tanto en su materia textual referencial como en sus propias técnicas ficcionales. Mediante un análisis de dos novelas breves ejemplares, El llanto y La prueba, centrado en las discrepancias espacio-temporales e incongruencias con respecto a la verosimilitud de la historia, se procura medir los efectos que provocan los procedimientos de Aira en sus lectores. Principalmente las aceleraciones desenfrenadas, las coincidencias melodramáticas y las escenas apocalípticas al final de muchos relatos suyos, cuestionan la frontera frágil entre la literatura de calidad y la literatura convencional de masas. Su gesto consciente de ruptura con toda forma de realismo unívoco y la polémica receptora inherente nos invitan a una reflexión sobre el valor literario que se construye en las distorsiones formales internas y en las combinaciones temáticas innovadoras de esta escritura.
Resumo:
Hexágono '71 fue una revista que se publicó entre 1971 y 1975, su ideólogo y director fue Edgardo Antonio Vigo (1928-1997). Una de las preguntas que frecuentemente nos realizamos al analizar una revista es ¿a quién está dirigida?, ¿cuál es su lector ideal?, ¿qué tipo de lectura propone? En esta ponencia trabajamos sobre una de las características de la revista Hexágono '71: el particular lugar en que coloca al receptor, implicándolo en un rol activo y decisivo en el contacto con la misma
Resumo:
La prolífica narrativa de César Aira ha despertado controversia entre sus lectores porque se caracteriza por una tensión paradójica entre, por un lado, una poética culta y un estilo hiperliterario, y por otro, una recurrencia de elementos massmediáticos tanto en su materia textual referencial como en sus propias técnicas ficcionales. Mediante un análisis de dos novelas breves ejemplares, El llanto y La prueba, centrado en las discrepancias espacio-temporales e incongruencias con respecto a la verosimilitud de la historia, se procura medir los efectos que provocan los procedimientos de Aira en sus lectores. Principalmente las aceleraciones desenfrenadas, las coincidencias melodramáticas y las escenas apocalípticas al final de muchos relatos suyos, cuestionan la frontera frágil entre la literatura de calidad y la literatura convencional de masas. Su gesto consciente de ruptura con toda forma de realismo unívoco y la polémica receptora inherente nos invitan a una reflexión sobre el valor literario que se construye en las distorsiones formales internas y en las combinaciones temáticas innovadoras de esta escritura.
Resumo:
The constant development of digital systems in radio communications demands the adaptation of the current receiving equipment to the new technologies. In this context, a new Software Defined Radio based receiver is being implemented with the aim of carrying out different experiments to analyze the propagation of signals through the atmosphere from a satellite beacon. The receiver selected for this task is the PERSEUS SDR from the Italian company Microtelecom s.r.l. It is a software defined VLF-LF-MF-HF receiver based on an outstanding direct sampling digital architecture which features a 14 bit 80 MSamples/s analog-to-digital converter, a high-performance FPGA-based digital down-converter and a high-speed 480 Mbit/s USB2.0 PC interface. The main goal is to implement the related software and adapt the new receiver to the current working environment. In this paper, SDR technology guidelines are given and PERSEUS receiver digital signal processing is presented with the most remarkable results.
Resumo:
En este estudio se ha realizado el diseño de un receptor de una central de Torre Central de energía solar para generación directa de vapor, mediante el uso de métodos numéricos, con un perfil de potencia incidente variable longitudinal y transversalmente. Para ello se ha dividido la geometría del receptor según el método de diferencias finitas, y se ha procedido a resolver las ecuaciones del balance de energía. Una vez resuelto el sistema de ecuaciones se dispone de la distribución de temperaturas en el receptor y se puede proceder a analizar los resultados así como a calcular otros datos de interés. ABSTRACT In this study it has been made a Central Receiver Solar Thermal Power Plant’s Receiver design for direct steam production, by using numerical methods, with a variable longitudinally and transversely income solar power profile. With this propose, the receiver’s geometry has been divided using the finite difference method, and the energy balance equations have been solved. Once the equations system has been solved, the receiver´s temperature distribution is known, and you can analyze the results as well as calculate other interesting data.
Resumo:
Using autoradiographic binding methodology with monoiodinated peptide YY together with the agonists neuropeptide Y (NPY) and NPY (13–36), as well as in situ hybridization with oligonucleotide probes complementary to the NPY Y2 receptor (Y2-R) mRNA, we have studied whether or not intracerebral prion inoculation affects Y2-Rs in male CD-1 mice. Monoiodinated peptide YY binding, mainly representing Y2-Rs, was down-regulated by 85% in the CA1 strata oriens and radiatum and by 50–65% in the CA3 stratum oriens 110–140 days postinoculation. In the CA3 stratum radiatum, where the mossy fibers from the dentate granule cells project, there was a significant decrease in PYY binding at 110–120 days. Y2-R mRNA, moderately expressed both in the CA1 and CA3 pyramidal cell layers and the granule cell layer in the dentate gyrus, showed a slight, but not significant, decrease in CA3 neurons 130 days postinoculation. The results indicate that the accumulation of the scrapie prion protein in the CA1–3 region strongly inhibits NPY binding at the Y2-Rs, which, however, is only marginally due to reduced Y2-R mRNA expression. The loss of the ability of NPY to bind to inhibitory Y2-Rs may cause dysfunction of hippocampal circuits and may contribute to the clinical symptoms in mouse scrapie.
Resumo:
To elucidate the role of neuropeptide Y (NPY)-Y1 receptor (Y1-R) in food intake, energy expenditure, and other possible functions, we have generated Y1-R-deficient mice (Y1-R−/−) by gene targeting. Contrary to our hypothesis that the lack of NPY signaling via Y1-R would result in impaired feeding and weight loss, Y1-R−/− mice showed a moderate obesity and mild hyperinsulinemia without hyperphagia. Although there was some variation between males and females, typical characteristics of Y1-R−/− mice include: greater body weight (females more than males), an increase in the weight of white adipose tissue (WAT) (approximately 4-fold in females), an elevated basal level of plasma insulin (approximately 2-fold), impaired insulin secretion in response to glucose administration, and a significant changes in mitochondrial uncoupling protein (UCP) gene expression (up-regulation of UCP1 in brown adipose tissue and down-regulation of UCP2 in WAT). These results suggest either that the Y1-R in the hypothalamus is not a key molecule in the leptin/NPY pathway, which controls feeding behavior, or that its deficiency is compensated by other receptors, such as NPY-Y5 receptor. We believe that the mild obesity found in Y1-R−/− mice (especially females) was caused by the impaired control of insulin secretion and/or low energy expenditure, including the lowered expression of UCP2 in WAT. This model will be useful for studying the mechanism of mild obesity and abnormal insulin metabolism in noninsulin-dependent diabetes mellitus.
Resumo:
Tese de mestrado, Biologia Molecular e Genética, Universidade de Lisboa, Faculdade de Ciências, 2016
Resumo:
Hexágono '71 fue una revista que se publicó entre 1971 y 1975, su ideólogo y director fue Edgardo Antonio Vigo (1928-1997). Una de las preguntas que frecuentemente nos realizamos al analizar una revista es ¿a quién está dirigida?, ¿cuál es su lector ideal?, ¿qué tipo de lectura propone? En esta ponencia trabajamos sobre una de las características de la revista Hexágono '71: el particular lugar en que coloca al receptor, implicándolo en un rol activo y decisivo en el contacto con la misma
Resumo:
Programa de doctorado: Actividad Física, Salud y Rendimiento Deportivo
Resumo:
We have shown Galanin(GAL) and Neuropeptide Y Y1(NPYY1) interactions at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers in the amygdala. The aim of this work was to analyze GAL/NPYY1R interactions in the Dentate Gyrus(DG) of the Hippocampus, using autoradiographic, in situ hybridization and in situ proximity ligation assay(PLA). Rats(n=6) were sacrificed 15 minutes or 5 hours after icv injections of GAL(3nmol) and DG sections were incubated with NPYY1R agonist [I125]-[Leu31,Pro34]PYY(25 pM) or NPYY1R-33PdATP specific probe, for autoradiography and in situ hybridization respectively. Autoradiograms were analyzed using NIH image analysis system and Student’s unpaired t-test was used. For PLA, DG sections were incubated with anti-GALR2 Rabbit(1:100) and anti-NPYY1R Goat(1:200). PLA signals were detected with PLA PLUS or MINUS probes for rabbit or goat/mouse antibodies. PLA signals were visualized by using a confocal microscope Leica TCS-SL confocal microscope(Leica). We observed that GAL significant increased the NPYY1R agonist [I125]-[Leu31,Pro34]PYY binding in the DG by 20% (p<0,05) and the NPYY1R mRNA expression in the granular layer of DG by 31% (p<0,001). Moreover, PLA-positive red clusters were found specifically in the polymorphic layer and subgranular zone of the DG. No PLA clusters were observed neither in the molecular layer of the DG nor in the corpus callosum, an area that seems to lack of GALR2 receptor. These results demonstrate a novel mechanism of interaction between GAL and NPY1R in the DG at receptor level, probably involving the formation of GALR2/NPYY1R heteroreceptor complexes. Study supported by Junta de Andalucia CVI6476.