Meditaçoes para todos os dias da semana, pelo exercicio das tres potencias da alma, conforme ensina S.to Ignacio fundador da Companhia de Jesu /

Mode of access: Internet.

Manifesto de sua magestade fidelissima el rei nosso senhor o senhor D. Miguel I.

Mode of access: Internet.

Un mercado beneficial: la mercantilización de beneficios eclesiásticos en Castilla y Portugal

Thanks to some classical and recent studies, we know the main features of the huge structure that served as financial support to the secular clergy in the Ancien Régime, the system of benefices. However, almost nothing has been said yet about the process that made possible the conformation around these benefices of a market of transnational nature, controlled by the Holy See, to which outflowed a great amount of capital from the Iberian Peninsula. So these pages are intended to sketch a research line, that of the commodification of ecclesiastical benefices, virtually unattended so far. It will be examined the instruments of this market, its practices and the comparative evolution of the phenomenon in cathedrals of Castile and Portugal.

Population genetics of Cerastoderma edule in Ria Formosa (southern Portugal): the challenge of understanding an intraspecific hotspot of genetic diversity

Coastal lagoons are highly variable environments that may act as hotspots of genetic diversity as a consequence of their ecological role as nursery habitats of marine species with both ecological and fisheries importance. The edible cockle (Cerastoderma edule) is a commercially important shellfish resource inhabiting coastal lagoons in Europe and their fisheries management urgently needs genetic studies to design appropriate strategies to promote the recovery of exploited populations. The aim of this study was to assess the C. edule genetic diversity and population structure at a small geographic scale, inside Ria Formosa coastal lagoon (southern Portugal) using mitochondrial cytochrome oxidase I sequences in six locations. Outcomes pointed to a common pattern of high haplotype diversity and non-significant genetic structuring inside the Ria Formosa lagoon. A high level of gene flow was detected between all localities and the presence of a single stock from a genetic point of view may be considered for fisheries management purposes. The existence of a high number of haplotypes and high values of haplotype diversity of C. edule in Ria Formosa lagoon could be consistent with the hypothesis that higher genetic diversity is expected in populations occurring in coastal lagoons, suggesting that lagoons could increase standing genetic variation and an adaptive potential of lagoon populations as an ecological response to a highly variable environment.

Sapientia, 1960, Vol. XV, nº 55 (número completo)

Contenido: Contemplación y acción / Octavio N. Derisi – El humanismo de Heidegger / José Ignacio Alcorta – Cultura o humanismo cristiano / Octavio N. Derisi – Notas y comentarios -- Bibliografía

Sapientia, 1953, Vol. VIII, nº 28 (número completo)

Contenido: Intolerancia de la verdad y tolerancia del amor / La Dirección – Definición de la metafísica : sus dificultades y su posibilidad / Reginaldo Garrigou-Lagrange O. P. – La oposición estética forma-contenido / Manuel B. Trías – Ética de la subjetividad : en torno a la ética de G. Marcel y K. Jarspers /José Ignacio Alcorta -- Notas y comentarios -- Bibliografía

Sapientia, 1949, Vol. IV, nº 13 (número completo)

Contenido: Para la constitución de un humanismo auténtico / La Dirección – La noética tomista y el idealismo / José Ignacio de Alcorta y Echevarría – Valor y existencia / Fritz Joachim V. Rintelen – Jaime Balmes (1810-1848) / F. J. Thonnard – Notas y comentarios -- Bibliografía

Sapientia, 1960, Vol. XV, nº 56 (número completo)

Contenido: Reflexiones en torno al sesquicentenario de la Revolución de Mayo / Octavio N. Derisi – Santo Tomás y la filosofía cristiana actual / Cornelio Fabro – El humanismo en Heidegger / José Ignacio Alcorta – Notas y comentarios -- Bibliografía

Sapientia, 1955, Vol. X, nº 35 (número completo)

Contenido: Del progreso en filosofía / La Dirección – Evolución de la verdad / Alberto García Vieyra – El sentimiento como revelador de lo ético / José Ignacio de Alcorta – Sobre algunos aspectos de la antropología filosófica actual en Alemania / Walter Brüning – Notas y comentarios -- Bibliografía

Sapientia, 1968, Vol. XXIII, nº 90 (número completo)

Contenido: La ubicación de la inteligencia / Octavio N. Derisi – La libertad en la filosofía de la integralidad / Alberto Caturelli – Conocimiento y ser / José I. Alcorta – Notas y comentarios -- Bibliografía

Sapientia, 1963, Vol. XVIII, nº 67 (número completo)

Contenido: Multiplicidad material y unidad espiritual / Octavio N. Derisi – Para una filosofía de la Universidad / Alberto Caturelli – La moral existencialista y la regulación racional tomista / José Ignacio Alcorta – La cultura y las culturas / Octavio N. Derisi – Notas y comentarios -- Bibliografía

Carta de El-Rei D. Manuel ao Rei Catholico narrando-lhe as viagens portuguezas à India desde 1500 até 1505

Esta obra saiu nas Memórias da comissão portuguesa para comemorar o centenário do descobrimento da América. Traz em apêncide a Relação análoga de Lunardo Cha Masser e dois documentos de Cantino e Pasqualigo. Contém, ainda, a primeira notícia impressa sobre o descobrimento do Brasil em carta ao Rei da Espanha.

A neural extracellular matrix-based method for in vitro hippocampal neuron culture and dopaminergic differentiation of neural stem cells

Background: The ability to recreate an optimal cellular microenvironment is critical to understand neuronal behavior and functionality in vitro. An organized neural extracellular matrix (nECM) promotes neural cell adhesion, proliferation and differentiation. Here, we expanded previous observations on the ability of nECM to support in vitro neuronal differentiation, with the following goals: (i) to recreate complex neuronal networks of embryonic rat hippocampal cells, and (ii) to achieve improved levels of dopaminergic differentiation of subventricular zone (SVZ) neural progenitor cells. Methods: Hippocampal cells from E18 rat embryos were seeded on PLL- and nECM-coated substrates. Neurosphere cultures were prepared from the SVZ of P4-P7 rat pups, and differentiation of neurospheres assayed on PLL- and nECM-coated substrates. Results: When seeded on nECM-coated substrates, both hippocampal cells and SVZ progenitor cells showed neural expression patterns that were similar to their poly-L-lysine-seeded counterparts. However, nECM-based cultures of both hippocampal neurons and SVZ progenitor cells could be maintained for longer times as compared to poly-L-lysine-based cultures. As a result, nECM-based cultures gave rise to a more branched neurite arborization of hippocampal neurons. Interestingly, the prolonged differentiation time of SVZ progenitor cells in nECM allowed us to obtain a purer population of dopaminergic neurons. Conclusions: We conclude that nECM-based coating is an efficient substrate to culture neural cells at different stages of differentiation. In addition, neural ECM-coated substrates increased neuronal survival and neuronal differentiation efficiency as compared to cationic polymers such as poly-L-lysine.

Alvará com força de Lei, pelo qual Vossa Alteza Real ha por bem regular a arqueação dos navios, empregados na conducção dos negros, que dos portos de Africa se exportão para os do Brasil; dando Vossa Alteza Real, por effeito dos seus incomparaveis sentimentos de humanidade, e benificencia as mais saudaveis, e benignas providencias em beneficio daquelles individuos : para Vossa Alteza Real ver / Francisco Xavier de Noronha Torrezão o fez

Referência: Bibliografia da Impressão Regia do Rio de Janeiro / Ana Maria de Almeida Camargo, Rubens Borba de Moraes, 1993. v. 2, p. 79.