937 resultados para René I, King of Naples and Jerusalem, 1409-1480.
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"The biographical part was written by Mr. Dibdin."--Lowndes, The bibliographer's manual of English literature.
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Mode of access: Internet.
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Includes index.
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Mode of access: Internet.
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Mode of access: Internet.
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Includes bibliographical references and index.
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Mode of access: Internet.
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Vols. 1-10 published at Toronto, by the Canada law book company, limited
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Mode of access: Internet.
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"The following stories are concerned mainly with incidents bearing on the career of the first sovereign of the Hawaiian archipelago, Kamehameha I."--Introd.
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"Lithoprinted."
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Includes bibliographical references.
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"Poems ('Vers libre') by Carmen Sylva": vol. II, p. 175-222.
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On t.-p. of v. 3: Illustrated with colored plates and drawings by Louis Agassiz Fuertes and Allan Brooks ... with a biograhical sketch of Edward Howe Forbush by John Bichard May.
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Background: Increased levels of tumor necrosis factor (TNF)-alpha and oxidative stress have been implicated as factors contributing to hepatic injury in fatty liver diseases. As steatosis is associated with an accelerated progression of fibrosis in chronic hepatitis C (HCV), we hypothesized that the messenger (m)RNA expression of genes involved with the production of reactive oxygen species, inflammation and cellular injury would be increased in liver tissue from subjects with steatosis and chronic HCV. Methods: Real-time polymerase chain reaction was performed to determine relative mRNA expression levels of collagen I, TNF-alpha, cytochrome P450 2E1 (CYP 2E1), transforming growth factor-beta1 and CD14 in liver biopsies from 38 patients with chronic HCV. The mRNA expression levels were compared between subjects with and without steatosis, fibrosis, and inflammation. Results: Multivariate analysis demonstrated that collagen I mRNA expression was increased by 199% in steatosis (P = 0.02), 85% in moderate to severe fibrosis (P = 0.02) and 157% in inflammation (P = 0.03). Livers of patients with steatosis also had an increase in TNF-alpha mRNA expression by 50% (P = 0.03) and CYP 2E1 expression by 37% (P = 0.04) compared with non-steatotic livers. Tumor necrosis factor-alpha protein was localized to Kupffer cells, bile ducts and portal inflammatory cells by immunohistochemistry. Conclusion: Increased expression of TNF-alpha may be involved in the pathogenesis of liver injury and progression of fibrosis in individuals who have steatosis in association with chronic HCV. (C) 2003 Blackwell Publishing Asia Pty Ltd.