Evaluation of short dietary questions from the 1995 National Nutrition Survey

Six of the short dietary questions used in the 1995 National Nutrition Survey (see box below) were evaluated for relative validity both directly and indirectly and for consistency, by documenting the differences in mean intakes of foods and nutrients as measured on the 24-hour recall, between groups with different responses to the short questions. 1. Including snacks, how many times do you usually have something to eat in a day including evenings? 2. How many days per week do you usually have something to eat for breakfast? 3. In the last 12 months, were there any times that you ran out of food and couldn’t afford to buy more? 4. What type of milk do you usually consume? 5. How many serves of vegetables do you usually eat each day? (a serve = 1/2 cup cooked vegetables or 1 cup of salad vegetables) 6. How many serves of fruit do you usually eat each day? (a serve = 1 medium piece or 2 small pieces of fruit or 1 cup of diced pieces) These comparisons were made for males and females overall and for population sub-groups of interest including: age, socio-economic disadvantage, region of residence, country of birth, and BMI category. Several limitations to this evaluation of the short questions, as discussed in the report, need to be kept in mind including: · The method for comparison available (24-hour recall) was not ideal (gold standard); as it measures yesterday’s intake. This limitation was overcome by examining only mean differences between groups of respondents, since mean intake for a group can provide a reasonable approximation for ‘usual’ intake. · The need to define and identify, post-hoc, from the 24-hour recall the number of eating occasions, and occasions identified by the respondents as breakfast. · Predetermined response categories for some of the questions effectively limited the number of categories available for evaluation. · Other foods and nutrients, not selected for this evaluation, may have an indirect relationship with the question, and might have shown stronger and more consistent responses. · The number of responses in some categories of the short questions eg for food security may have been too small to detect significant differences between population sub-groups. · No information was available to examine the validity of these questions for detecting differences over time (establishing trends) in food habits and indicators of selected nutrient intakes. By contrast, the strength of this evaluation was its very large sample size, (atypical of most validation studies of dietary assessment) and thus, the opportunity to investigate question performance in a range of broad population sub-groups compared with a well-conducted, quantified survey of intakes. The results of the evaluation are summarised below for each of the questions and specific recommendations for future testing, modifications and use provided for each question. The report concludes with some general recommendations for the further development and evaluation of short dietary questions.

European 1: A globally important clonal complex of Mycobacterium bovis

We have identified a globally important clonal complex of Mycobacterium bovis by deletion analysis of over one thousand strains from over 30 countries. We initially show that over 99% of the strains of M. bovis, the cause of bovine tuberculosis, isolated from cattle in the Republic of Ireland and the UK are closely related and are members of a single clonal complex marked by the deletion of chromosomal region RDEu1 and we named this clonal complex European 1 (Eu1). Eu1 strains were present at less than 14% of French, Portuguese and Spanish isolates of M. bovis but are rare in other mainland European countries and Iran. However, strains of the Eu1 clonal complex were found at high frequency in former trading partners of the UK (USA, South Africa, New Zealand, Australia and Canada). The Americas, with the exception of Brazil, are dominated by the Eu1 clonal complex which was at high frequency in Argentina, Chile, Ecuador and Mexico as well as North America. Eu1 was rare or absent in the African countries surveyed except South Africa. A small sample of strains from Taiwan were non-Eu1 but, surprisingly, isolates from Korea and Kazakhstan were members of the Eu1 clonal complex. The simplest explanation for much of the current distribution of the Eu1 clonal complex is that it was spread in infected cattle, such as Herefords, from the UK to former trading partners, although there is evidence of secondary dispersion since. This is the first identification of a globally dispersed clonal complex M. bovis and indicates that much of the current global distribution of this important veterinary pathogen has resulted from relatively recent International trade in cattle. Crown Copyright (C) 2011 Published by Elsevier B.V. All rights reserved.

Human peripheral blood V alpha 24(+) V beta 11(+) NKT cells expand following administration of alpha-galactosylceramide-pulsed dendritic cells

Background and Objectives We have undertaken the first clinical trial involving the administration of alpha-GalactosylCeramine (alpha-GalCer)-pulsed dendritic cells (DCs) to human subjects, to determine safety, optimal dose, optimal administration route and immunological effects. Materials and Methods Subjects (n = 4) with metastatic malignancy received two infusions of alpha-GalCer-pulsed DCs intravenously, and two infusions intradermally. The percentages of Valpha24 Vbeta11 NKT cells in peripheral blood (PB) were determined by three-colour flow cytometry and the PB NKT cell numbers were calculated using the total number of PB lymphocytes/ml determined by automated full-blood counts. Results No serious treatment related adverse events were observed during the study period. Administration of alpha-GalCer-pulsed DCs in vivo can significantly (P < 0.03) increase PB Valpha24(+) Vbeta11(+) NKT cell numbers above pretreatment baseline levels after the transient fall in the NKT numbers within 48 h. Conclusions Administration of alpha-GalCer-pulsed DCs is well tolerated, modulates PB Valpha24(+) Vbeta11(+) NKT cells and may have a role in the therapy of malignancies sensitive to activities of Valpha24(+) Vbeta11(+) NKT cells, or for autoimmune diseases.

Sele????o e treinamento: sua articula????o

Escrito pelo Sr. Belmiro Siqueira, funcion??rio de carreira da ??rea de administra????o que atuou nas esferas estadual e federal, ocupou v??rios cargos no Departamento Administrativo do Servi??o P??blico (DASP), dentre eles o de diretor geral. Foi vice-presidente do Conselho Federal de Administra????o (CFA) e d?? nome ao concurso nacional que anualmente ?? promovido pelo Sistema CFA/CRAs, o ???Pr??mio Belmiro Siqueira de Administra????o???, sendo patrono dos administradores. Em seu texto, afirma que a Administra????o P??blica, diante de sua atua????o peculiar e, muitas vezes, ??nica empregadora de certos tipos de profissionais, tem de preparar os servidores de que necessita, desenvolvendo para esse fim recrutamentos planejados que incluam programas de ???pre-entry training???, ou treinamento pr??vio. Acredita que a orienta????o proveniente da sele????o e treinamento eficazes contribui fortemente para a prepara????o de servidores para o exerc??cio eficiente de determinados cargos. Para Belmiro, diante das atribui????es especializadas e as r??pidas mudan??as nas exig??ncias feitas ao Servi??o P??blico, dificilmente uma sele????o que n??o contenha o treinamento conseguir?? formar contingentes desej??veis e habilitados de servidores para a execu????o das vastas finalidades do Estado. ?? poss??vel dizer que a sele????o depende, fundamentalmente, do treinamento pr??vio; pois, sem ele, o recrutamento ?? falho e caro, uma vez que n??o estar?? assegurada a prepara????o dos interessados para as atividades. E sem representativo grupo de candidatos, ser??o pobres os resultados da sele????o.

Perman??ncia e mudan??a no setor p??blico

Por ter se convertido em espa??o e instrumento das concilia????es com o passado, o Estado brasileiro n??o p??de se tornar completamente moderno e autenticamente republicano. N??o teve como deixar de se submeter a pr??ticas e concep????es fortemente vinculadas ao tradicional privatismo das elites. Tornou-se um Estado moderno enxertado de patrimonialismo, cuja burocracia legitima seu poder atrav??s do recurso a procedimentos clientelistas e fisiol??gicos.

Reflexões sobre a apropriação de objetos na arte contemporânea

Nesta dissertação discutimos os movimentos em torno da temática da apropriação evidenciando o deslocamento do objeto de uso comum para o campo da arte em três movimentos paradigmáticos: o Dadaísmo, o Surrealismo e o Novo Realismo, e seus desdobramentos na arte contemporânea no sentido de legado cultural. Permitimo-nos transitar pelas demais vertentes dos processos de apropriação na arte nova-iorquina e europeia seguindo as propostas da arte com objetos. Investigamos os processos envolvidos nas controvérsias do ready-made, executado por Marcel Duchamp desde 1913, para dar partida ao percurso histórico das manifestações onde ocorre o objet trouvé, a colagem e a assemblagem. Nosso objetivo é responder à pergunta com a qual o filósofo Arthur C. Danto inicia suas investigações filosóficas acerca das apropriações e condições que fazem de um objeto comum uma obra de arte. Para tanto buscamos as teorias de Abrahan Moles e Jean Baudrillard acerca do objeto industrializado e Roland Barthes com as questões metalingüísticas de sua função-signo. Para discutir tais relações da arte com os objetos, recorremos aos textos de Peter Bürger, André Breton, Pierre Restany, Gregory Battcock, Walter Benjamin, Hal Foster e outros. Destacamos alguns trabalhos artísticos, evidenciando o objeto caixa, tratado como um utilitário com forma e finalidade definidas, reafirmando-se como objeto de consumo, no discurso sobre a poética do espaço de Gaston Bachelard. A pesquisa propõe analisar as transformações radicais das estruturas conservadoras da arte e especular sobre o gesto de apropriação dos objetos, com algumas reflexões direcionadas sobre o objeto e a transgressividade da apropriação como experiência de tensão e poder.

A importância do ensino do direito penal-criminal

“Portugal manteve, em 2013, o 33.º lugar no Índice de Perceção da Corrupção da organização Transparência Internacional, mas perdeu pontuação”. E: “Na última década, o país no mundo que mais se depreciou em termos de transparência foi justamente Portugal”, “enfatizou o vice-presidente da associação Transparência e Integridade, Paulo Morais”. Abstract: "Portugal maintained in 2013, the 33 place in the Perception Index of Transparency International Corruption, but lost points." And: "In the last decade, the country in the world that most depreciated in terms of transparency was precisely Portugal", "emphasized the Vice President of Transparency and Integrity association, Paulo Morais."

Injustiça para com a cidade de Barcelos

Começarei com um Princípio Fundamental Constitucional que está (ainda) em vigor: o Direito à Justiça. Art. 20º da Constituição da República Portuguesa: “Acesso ao direito e tutela jurisdicional efectiva”: “1. A todos é assegurado o acesso ao direito e aos tribunais para defesa dos seus direitos e interesses legalmente protegidos, não podendo a justiça ser denegada por insuficiência de meios económicos.”. Abstract: I will begin with a Constitutional Fundamental Principle that is (still) in force: the Right to Justice. Art 20 of the Constitution of the Portuguese Republic. "Access to law and effective judicial protection": "1. Everyone is guaranteed access to the law and the courts to defend their legally protected rights and interests, and justice may not be denied for insufficient economic means. ".

A justa causa no despedimento

Diz o art. 53º da Constituição: “É garantida aos trabalhadores a segurança no emprego, sendo proibidos os despedimentos sem justa causa ou por motivos políticos ou ideológicos.”. O direito fundamental da “Segurança no emprego” é uma das principais conquistas da social-democracia e/ou do socialismo democrático europeus, entre outras ideologias políticas e religiosas. Abstract: Says the art. 53 of the Constitution: "It is guaranteed to security workers in employment, being prohibited the unfair dismissal or for political or ideological reasons.". The fundamental right of "Job security" is one of the main achievements of social democracy and / or the European democratic socialism, among other political and religious ideologies.

Tribunal Constitucional Alemão: “reestruturação”?

Porque é que, do ponto de vista físico, o Tribunal Constitucional, o Supremo Tribunal de Justiça, a Procuradoria-Geral da República, a Provedoria da Justiça, entre inúmeras outras instituições nacionais, num terreno pequeno, têm que ser todas em Lisboa? (...). Aliás, v.g., “a PGR já aconselhou o Governo a levar os contratos-swap a tribunal” (Sol, 3/11/13). Abstract: Why, from the physical point of view, the Constitutional Court, the Supreme Court, the Attorney General's Office, the Office of the Ombudsman, among many other national, a small plot of land, they must all be in Lisbon? (...). Moreover, eg, "the PGR has advised the Government to take the swap contracts to court" (Sun, 11/03/13).

Mediação penal: a importância no ensino do direito e solicitadoria

A mediação penal, como meio para alcançar a chamada justiça restaurativa, dum modo mais rápido, tem sido uma preocupação dos últimos governos, duma cor ou doutra. O “Regime da Mediação Penal” pauta-se em Portugal pela Lei nº 21/2007, de 12/2, até à Lei nº 29/2013, de 19/4 e que entrou em vigor em 19/5 do mesmo ano. Abstract: Mediation as a means to achieve the so-called restorative justice, with a faster, has been a concern of the past governments, with a color or another. The "Regime of Criminal Mediation" agenda in Portugal by Law No. 21/2007, of 12/2, to Law No. 29/2013, of 19/4 and entered into force on 19/5 the same year.