Mischehen und Ehescheidungen

Ph. Schwartz

Bilanz der Aufbauarbeit in Palästina

Ph. Schwartz

Die Juden im bayerischen Unterrichtswesen

Ph. Schwartz

Sozialer Auf- und Abstieg im deutschen Volk [Rezension]

Ph. Schwartz

Bedrohter Lebensaufbau : Vergreisung der jüdischen Bevölkerung - Der internationale Geburtenstreik - Die Quellen des Münchener Wirtschaftsleben

Ph. Schwartz

Soziologie der Juden [Rezension] : das neue Werk Ruppins

Ph. Schwartz

Dielectrophoretic approaches to sample preparation and analysis

Dielectrophoresis (DEP) has been used to manipulate cells in low-conductivity suspending media using AC electrical fields generated on micro-fabricated electrode arrays. This has created the possibility of performing automatically on a micro-scale more sophisticated cell processing than that currently requiring substantial laboratory equipment, reagent volumes, time, and human intervention. In this research the manipulation of aqueous droplets in an immiscible, low-permittivity suspending medium is described to complement previous work on dielectrophoretic cell manipulation. Such droplets can be used as carriers not only for air- and water-borne samples, contaminants, chemical reagents, viral and gene products, and cells, but also the reagents to process and characterize these samples. A long-term goal of this area of research is to perform chemical and biological assays on automated, micro-scaled devices at or near the point-of-care, which will increase the availability of modern medicine to people who do not have ready access to large medical institutions and decrease the cost and delays associated with that lack of access. In this research I present proofs-of-concept for droplet manipulation and droplet-based biochemical analysis using dielectrophoresis as the motive force. Proofs-of-concept developed for the first time in this research include: (1) showing droplet movement on a two-dimensional array of electrodes, (2) achieving controlled dielectric droplet injection, (3) fusing and reacting droplets, and (4) demonstrating a protein fluorescence assay using micro-droplets. ^

A full pedigree based method for the statistical assessment of genetic anticipation

Genetic anticipation is defined as a decrease in age of onset or increase in severity as the disorder is transmitted through subsequent generations. Anticipation has been noted in the literature for over a century. Recently, anticipation in several diseases including Huntington's Disease, Myotonic Dystrophy and Fragile X Syndrome were shown to be caused by expansion of triplet repeats. Anticipation effects have also been observed in numerous mental disorders (e.g. Schizophrenia, Bipolar Disorder), cancers (Li-Fraumeni Syndrome, Leukemia) and other complex diseases. ^ Several statistical methods have been applied to determine whether anticipation is a true phenomenon in a particular disorder, including standard statistical tests and newly developed affected parent/affected child pair methods. These methods have been shown to be inappropriate for assessing anticipation for a variety of reasons, including familial correlation and low power. Therefore, we have developed family-based likelihood modeling approaches to model the underlying transmission of the disease gene and penetrance function and hence detect anticipation. These methods can be applied in extended families, thus improving the power to detect anticipation compared with existing methods based only upon parents and children. The first method we have proposed is based on the regressive logistic hazard model. This approach models anticipation by a generational covariate. The second method allows alleles to mutate as they are transmitted from parents to offspring and is appropriate for modeling the known triplet repeat diseases in which the disease alleles can become more deleterious as they are transmitted across generations. ^ To evaluate the new methods, we performed extensive simulation studies for data simulated under different conditions to evaluate the effectiveness of the algorithms to detect genetic anticipation. Results from analysis by the first method yielded empirical power greater than 87% based on the 5% type I error critical value identified in each simulation depending on the method of data generation and current age criteria. Analysis by the second method was not possible due to the current formulation of the software. The application of this method to Huntington's Disease and Li-Fraumeni Syndrome data sets revealed evidence for a generation effect in both cases. ^

Na 1 Nachlass Max Horkheimer, 48 - Korrespondenzen u.a. an Thorsten Sellin (p. I 22, 227-395)

2 Briefe zwischen Luther L. Gobbel und Max Horkheimer, 28.09.1938, 03.10.1938; 2 Briefe zwischen Russell M. Story und Max Horkheimer, 15.03.1938; 1 Brief von Max Horkheimer an Ralph E. Boothby, 14.03.1938; 1 Brief von Max Horkheimer an Roswell G. Ham, 13.01.1938; 2 Briefe von Carl Schurz von der Memorial Foundation Philadelphia an Max Horkheimer, 1940; 7 Briefe zwischen Helen Schuster und Max Horkheimer, 1936, 1937, 1947-1948; 1 Brief von Liesel Schwaibold an Max Horkheimer, 19.01.1937; 6 Briefe zwischen Ph. Schwartz und Max Horkheimer, 1936-1937; 4 Briefe zwischen Ph. Schwart an Ludwig Jekels, 1936, 1937; 1 Brief von Ph. Schwartz an Karl Landauer,; 1 Brief von Eugen Schwarz an den Vater von Max Horkheimer, 08.12.1937; 1 Brief von Max Horkheimer an Eugen Schwarz, 31.12.1937; 5 Briefe zwischen Olga Therese Schwarz und Max Horkheimer, 1942; 8 Briefe zwischen Alfred Schweizer und Max Horkheimer, 1940-1941; 1 Lebenslauf von Arthur Heinrich Schweitzer und 1 Bericht über Arthur Heinrich Schweitzer; 1 Brief von Josef Schwoner an Max Horkheimer, 20.06.1941; 1 Brief von Max Horkheimer an L. H. Seelye, 01.04.1935; 1 Brief von Max Horkheimer an Dora Segall-Ziegellaub, 01.10.1935; 6 Briefe zwischen Matyes Seiber und Max Horkheimer, Juli 1936, 1936; 2 Briefe zwischen Alfred Seidenmann und Max Horkheimer, 29.02.1940, 12.03.1940 sowie Briefwechsel mit dem American Freinds Service Committee, Phiadelphia; 2 Briefe zwischen dem American Friends Service Committee und Max Horkheimer, 12.09.1940; 3 Rundschreiben von der Selbsthilfe Deutscher Ausgewanderter New York, 1937-1938; Antworten auf einen Fragebogen des Selective Service Occupational Questionnaire von Max Horkheimer, 27.10.1942; 1 Brief vom Selfhelp of Emigres from Central Europe an Margot von Mendelssohn, 22.12.1948; 8 Briefe zwischen Edwin R. A. Seligman und Max Horkheimer, 1938-1939; 1 Brief von Max Horkheimer an Eustace Seligman, 11.03.1940; 1 Brief von Seligmann und Cia an Friedrich Pollock, 06.04.1936; 2 Brife zwischen Milton C. Seligman und Max Horkheimer, 1947; 1 Brief Stephen Schäfer an Thorsten Sellin, 07.02.1939; 17 Briefe zwischen Thorsten Sellin und Max Horkheimer, 1938-1941; 1 Brief von der Sherwin Cody School of English an Max Horkheimer, 06.02.1939; 3 Briefe und 1 Beilage zwischen Edward A. Shils und Max Horkheimer, 1938; 10 Briefe zwischen James T. Shotwell und Max Horkheimer, 01.07.1940-1941;

Romanian Volach

by Abe Schwartz

Der Knocheninhalt eines Waldohreneulengewölles

Von Dr. Martin Schwartz

Beiträge zur Ernährungsbiologie unserer körnerfressenden Singvögel

Von Dr. Martin Schwartz