912 resultados para parameterized expectations
Resumo:
We examine the evolution of monetary policy rules in a group of inflation targeting countries (Australia, Canada, New Zealand, Sweden and the United Kingdom) applying moment- based estimator at time-varying parameter model with endogenous regressors. Using this novel flexible framework, our main findings are threefold. First, monetary policy rules change gradually pointing to the importance of applying time-varying estimation framework. Second, the interest rate smoothing parameter is much lower that what previous time-invariant estimates of policy rules typically report. External factors matter for all countries, albeit the importance of exchange rate diminishes after the adoption of inflation targeting. Third, the response of interest rates on inflation is particularly strong during the periods, when central bankers want to break the record of high inflation such as in the U.K. or in Australia at the beginning of 1980s. Contrary to common wisdom, the response becomes less aggressive after the adoption of inflation targeting suggesting the positive effect of this regime on anchoring inflation expectations. This result is supported by our finding that inflation persistence as well as policy neutral rate typically decreased after the adoption of inflation targeting.
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Although stress has been a longstanding issue in organizations and management studies, it has never been studied in relation to Public Service Motivation. This article therefore aims to integrate PSM into the job demands-job resources model of stress in order to determine whether PSM might contribute to stress in public organizations. Drawing upon original data from a questionnaire in a Swiss municipality, this study unsurprisingly shows that "red tape" is an antecedent of stress perception, whereas satisfaction with organizational support, positive feedback, and recognition significantly decrease the level of perceived stress. Astonishingly, the empirical results show that PSM is positively and significantly related to stress perception. By increasing individuals' expectations towards their jobs, PSM might thus contribute to increased pressure on public agents. Ultimately, this article investigates the "dark side" of PSM, which has been neglected by the literature thus far.
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Objectives: Imatinib has been increasingly proposed for therapeutic drug monitoring (TDM), as trough concentrations (Cmin) correlate with response rates in CML patients. This analysis aimed to evaluate the impact of imatinib exposure on optimal molecular response rates in a large European cohort of patients followed by centralized TDM.¦Methods: Sequential PK/PD analysis was performed in NONMEM 7 on 2230 plasma (PK) samples obtained along with molecular response (PD) data from 1299 CML patients. Model-based individual Bayesian estimates of exposure, parameterized as to initial dose adjusted and log-normalized Cmin (log-Cmin) or clearance (CL), were investigated as potential predictors of optimal molecular response, while accounting for time under treatment (stratified at 3 years), gender, CML phase, age, potentially interacting comedication, and TDM frequency. PK/PD analysis used mixed-effect logistic regression (iterative two-stage method) to account for intra-patient correlation.¦Results: In univariate analyses, CL, log-Cmin, time under treatment, TDM frequency, gender (all p<0.01) and CML phase (p=0.02) were significant predictors of the outcome. In multivariate analyses, all but log-Cmin remained significant (p<0.05). Our model estimates a 54.1% probability of optimal molecular response in a female patient with a median CL of 14.4 L/h, increasing by 4.7% with a 35% decrease in CL (percentile 10 of CL distribution), and decreasing by 6% with a 45% increased CL (percentile 90), respectively. Male patients were less likely than female to be in optimal response (odds ratio: 0.62, p<0.001), with an estimated probability of 42.3%.¦Conclusions: Beyond CML phase and time on treatment, expectedly correlated to the outcome, an effect of initial imatinib exposure on the probability of achieving optimal molecular response was confirmed in field-conditions by this multivariate analysis. Interestingly, male patients had a higher risk of suboptimal response, which might not exclusively derive from their 18.5% higher CL, but also from reported lower adherence to the treatment. A prospective longitudinal study would be desirable to confirm the clinical importance of identified covariates and to exclude biases possibly affecting this observational survey.
Resumo:
The ancient Greek medical theory based on balance or imbalance of humors disappeared in the western world, but does survive elsewhere. Is this survival related to a certain degree of health care efficiency? We explored this hypothesis through a study of classical Greco-Arab medicine in Mauritania. Modern general practitioners evaluated the safety and effectiveness of classical Arabic medicine in a Mauritanian traditional clinic, with a prognosis/follow-up method allowing the following comparisons: (i) actual patient progress (clinical outcome) compared with what the traditional 'tabib' had anticipated (= prognostic ability) and (ii) patient progress compared with what could be hoped for if the patient were treated by a modern physician in the same neighborhood. The practice appeared fairly safe and, on average, clinical outcome was similar to what could be expected with modern medicine. In some cases, patient progress was better than expected. The ability to correctly predict an individual's clinical outcome did not seem to be better along modern or Greco-Arab theories. Weekly joint meetings (modern and traditional practitioners) were spontaneously organized with a modern health centre in the neighborhood. Practitioners of a different medical system can predict patient progress. For the patient, avoiding false expectations with health care and ensuring appropriate referral may be the most important. Prognosis and outcome studies such as the one presented here may help to develop institutions where patients find support in making their choices, not only among several treatment options, but also among several medical systems.
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In the recent years most libraries have focused on mass digitization programs and keeping electronic born documents, showing and organizing them in a repository. While those repositories have evolved to a much more manageable systems focusing on the user expectations and introducing web 2.0 tools, digital preservation is still in the to-do list of most of them. There is quite a lot of studies focused on preservation and some complex models exist, unfortunately, very few practical systems are running and its quite difficult for a library to get involved in a solution already tested by others. The CBUC (Consortium of University Catalan Libraries) runs TDX, an ETD repository now keeping more than 10.000 full text thesis from any of the 12 university members. After 10 years running TDX a solid preservation system was needed to ensure every thesis would be kept as it was regardless what happens to the repository. The perfect solution was found in the MetaArchive cooperative, this is the effort of many insitutions to keep a copy of each other content through a newtwork using the LOCKSS software as a mechanism to keep track of any change. The presentation will shortly introduce what TDX and MetaArchive is but will, in a practical way, show how the LOCKSS network for presrervation works. Finally a summary of the benefits of the overall experience will be shown.
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We characterize double adjunctions in terms of presheaves and universal squares, and then apply these characterizations to free monads and Eilenberg-Moore objects in double categories. We improve upon an earlier result of Fiore-Gambino-Kock in [7] to conclude: if a double category with cofolding admits the construction of free monads in its horizontal 2-category, then it also admits the construction of free monads as a double category horizontally and vertically, and also in its vertical 2-category. We also prove that a double category admits Eilenberg-Moore objects if and only if a certain parameterized presheaf is representable. Along the way, we develop parameterized presheaves on double categories and prove a double Yoneda Lemma.
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Aquest treball analitza, mitjançant un petit corpus de textos mèdics especialitzats publicats en llengua espanyola d'Espanya (13.470 paraules) i llengua russa (12.318 paraules), els usos i freqüències dels tipus oracionals i dels girs de participi i gerundi en el llenguatge científic. L'objectiu del treball és descriure aquests aspectes sintàctics de la prosa científica original en aquestes dues llengües per tal de conèixer i evitar els calcs sintàctics en la traducció dels textos mèdics. Una sintaxi sense calcs ajuda a adequar el text meta a les expectatives del lector, en aquest cas l'especialista mèdic
Resumo:
Recent technological advances in remote sensing have enabled investigation of the morphodynamics and hydrodynamics of large rivers. However, measuring topography and flow in these very large rivers is time consuming and thus often constrains the spatial resolution and reach-length scales that can be monitored. Similar constraints exist for computational fluid dynamics (CFD) studies of large rivers, requiring maximization of mesh-or grid-cell dimensions and implying a reduction in the representation of bedform-roughness elements that are of the order of a model grid cell or less, even if they are represented in available topographic data. These ``subgrid'' elements must be parameterized, and this paper applies and considers the impact of roughness-length treatments that include the effect of bed roughness due to ``unmeasured'' topography. CFD predictions were found to be sensitive to the roughness-length specification. Model optimization was based on acoustic Doppler current profiler measurements and estimates of the water surface slope for a variety of roughness lengths. This proved difficult as the metrics used to assess optimal model performance diverged due to the effects of large bedforms that are not well parameterized in roughness-length treatments. However, the general spatial flow patterns are effectively predicted by the model. Changes in roughness length were shown to have a major impact upon flow routing at the channel scale. The results also indicate an absence of secondary flow circulation cells in the reached studied, and suggest simpler two-dimensional models may have great utility in the investigation of flow within large rivers. Citation: Sandbach, S. D. et al. (2012), Application of a roughness-length representation to parameterize energy loss in 3-D numerical simulations of large rivers, Water Resour. Res., 48, W12501, doi: 10.1029/2011WR011284.
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El estudio analiza en profundidad las experiencias migratorias de los extranjeros que es encuentran en prisión, cual es su situación familiar y social aquí y en su país, la trayectoria delictiva y su experiencia penitenciaria, así como las expectativas de futuro cuando salga de prisión.
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L’augment del nombre de persones estrangeres que s’ha produït al llarg dels darrers anys va comportar que l’any 2008 la Direcció General de Recursos i Règim Penitenciari (DGRRP a partir d’ara) plantegés al Centre d’Estudis Jurídics i Formació Especialitzada la necessitat de conèixer més en profunditat aquesta població i les seves característiques i necessitats específiques. Diversos interrogants concrets formaven part d’aquella demanda inicial i van quedar explícitament recollits en els objectius de la recerca que presentarem tot seguit. Un tema destacat va ser des del principi la constatació de les dificultats d’integració social de les persones estrangeres empresonades un cop acomplerta la pena, en el marc del complex context legal que regula l’estrangeria al nostre país. La finalitat d’aquesta recerca és donar un coneixement ampli i global de la realitat dels estrangers als centres penitenciaris catalans i de les seves possibilitats de futur, apuntant recomanacions que puguin ajudar la DGRRP a intervenir amb més eficàcia en aquest tema de gran actualitat i complexitat.
Resumo:
El estudio recoge los perfiles de los extranjeros que se encuentran en las prisiones catalanas, cual ha sido su trayectoria migratoria hasta el momento actual, qué expectativas tienen respecto a su futuro, así como sus opiniones en relación a su situación en prisión y el trato que recibe por parte de las autoridades penitenciarias. También se analiza pormenorizadamente su situación administrativa y de regularización. El estudio termina con 29 recomendaciones para la mejora de todos los ámbitos de la intervención penitenciaria.
Resumo:
Aquest treball de recerca té la finalitat de conèixer com noves generacions de mestres van construint la seva identitat professional. Com que la recerca es situa a l’inici del seu pas per la formació inicial, el que es pretén analitzar són les concepcions i l’experiència prèvies que han tingut amb el món docent durant la seva trajectòria escolar. Es vol comprendre quines poden haver estat les motivacions que les han i els han portat realment a escollir la carrera de Mestres, quines expectatives tenen sobre la professió des de la vivència personal de ser testimonis d’una professió que ara volen convertir en la seva. El disseny respon a una investigació de caràcter exploratori i descriptiu i el mètode d’investigació s’ha basat en l’anàlisi de contingut de textos autobiogràfics elaborats en el context d’una assignatura de primer de Grau en les carreres de Mestres. La informació s’ha analitzat amb el programa d’anàlisi qualitativa Atlas.ti.
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La recerca Atenció Primària: una aproximació a l'experiència vital de l'educand com a element educatiu, posa de relleu la importància de l'experiència viscuda en un individu com a element motivador i capacitador de les pròpies expectatives personals, de les ganes de superació en el procés educatiu que s'està duent a terme entre l'educador o educadora i l'educand com a subjecte de l'experiència. El treball que presento vol ser una primera aproximació a un element tan important com és l'experiència vital de l'educand. Preguntes com quin paper juga l'experiència, el record, la posada en pràctica i la seva recuperació, sempre des d'un punt de vista educatiu i no terapèutic, són les que m'he plantejat en la recerca. Exploro com la recuperació d’allò que cadascú viu com a bon saber i posar-lo en pràctica de nou, pot ser un element facilitador en el procés educatiu. Reflexionar sobre unes accions ja realitzades és tornar-les a pensar des d'una memòria reflexiva, perquè no comencem de zero, sinó que comencem des d'aquella acció que en el seu moment ja ens va dur a un resultat positiu. Suposa aprendre a pensar millor, a utilitzar el pensament com un processador de la experiència i la informació. L’educador/a social, en aquesta relació, fa “de mirall” del propi educand, ajudant a sortir-se'n, acompanyant-lo en el recorregut de l'aprenentatge.
Resumo:
Investigación producida a partir de una estancia en Buenos Aires en septiembre del 2007. Los procesos de consolidación de las naciones-estado llevan consigo una serie de políticas y prácticas que se focalizan en la construcción del "pueblo". Particularmente, la construcción del estado nacional argentino en el siglo XIX implicó la definición -por parte de los grupos de poder- de un pueblo que cumpliera con las expectativas que se esperaban de una joven nación que se encaminaba hacia la civilización y el progreso, es decir, lo que en esa época se correspondía con un imaginario de pueblo blanco y europeo. Así, se propiciaron políticas de erosión de quienes habitaban en el territorio nacional pero que no cumplían con aquellos mandatos, promoviendo su “invisibilización”. Nosotros trabajamos una de estas comunidades erosionadas de la memoria y de la historia nacional argentina, la comunidad de afrodescendientes de Buenos Aires. El objeto de la investigación que se está llevando a cabo es justamente el análisis de la población afroargentina de Buenos Aires en las últimas décadas del siglo XIX, un momento en que su presencia e historia estaban siendo negadas de los discursos y de las prácticas. Esta investigación de corte histórico-antropológico necesita para su consecución de un trabajo exhaustivo de archivos, objetivo principal de la beca de investigación fuera de Cataluña. Lo que se intentó en el viaje fue encontrar y rescatar fuentes que permitieran entrever las dinámicas de esta comunidad, sus formas de resistir y/o de negociar un estado nacional cada vez más fuerte y que sentaba las bases de lo que debía ser el “pueblo argentino”.
Resumo:
The present doctoral dissertation is aimed at analyzing how and with what consequences gay father families and their children’s schools negotiate possible differences in the construction of family and gender at home and in the families’ social milieus. This objective fits in with the broader goal of researching how family-school interactons are influenced by the social context such as hegemonic masculinity (Connell, 2002). The thesis is based on qualitative fieldwork carried out with 18 nonheterosexual parent families in Spain, comprising 30 interviews with 44 people. The principal participant group were 14 de novo (adoptive and surrogacy) gay father families with resident preadolescent children. The findings revealed that all the de novo families assumed open communication strategies at school with inclusive consequences: apart from incidental questions and reactions of surprise, the children did not suffer homophobic bullying. The analisis showed that the necessary condition for inclusion was not the open communication but rather illocutionary orientation (Habermas, 1984; Soler & Flecha, 2010), understood as the parents’ sensitivity to the attitudes of their children and schools. The schools received the families in an inclusive manner, which, however, was only receptive and not proactive, therefore some of the families (reconstituted ones), coerced by the social context, got excluded. Gender relations at home were predominantly androgynous, and outside home predominantly traditional, yet the children negotiated this difference with inclusive consequences. They participated in hegemonic collective practices, thus confirming the thesis on the similarity between homo- and heterosexual-parent families (Golombok, 2006). Consistently, also the families’ identity politics was “assimilationist” and non-queer. Admittedly, the analisis showed that such a politics was increased by social expectations. Still, the findings suggest that educational and other family policies should draw on broad agendas of gender and family diversity rather than on the politics of difference and the unique status of LGB families.