Genomic analysis of the blood attributed to Louis XVI (1754-1793), king of France.

A pyrographically decorated gourd, dated to the French Revolution period, has been alleged to contain a handkerchief dipped into the blood of the French king Louis XVI (1754-1793) after his beheading but recent analyses of living males from two Bourbon branches cast doubts on its authenticity. We sequenced the complete genome of the DNA contained in the gourd at low coverage (similar to 2.5x) with coding sequences enriched at a higher similar to 7.3x coverage. We found that the ancestry of the gourd's genome does not seem compatible with Louis XVI's known ancestry. From a functional perspective, we did not find an excess of alleles contributing to height despite being described as the tallest person in Court. In addition, the eye colour prediction supported brown eyes, while Louis XVI had blue eyes. This is the first draft genome generated from a person who lived in a recent historical period; however, our results suggest that this sample may not correspond to the alleged king.

Research Priorities for seabirds: Improving seabird conservation and management in the 21st century

Seabirds are facing a growing number of threats in both terrestrial and marine habitats, and many populations have experienced dramatic changes over past decades. Years of seabird research have improved our understanding of seabird populations and provided a broader understanding of marine ecological processes. In an effort to encourage future research and guide seabird conservation science, seabird researchers from 9 nations identified the 20 highest priority research questions and organized these into 6 general categories: (1) population dynamics, (2) spatial ecology, (3) tropho-dynamics, (4) fisheries interactions, (5) response to global change, and (6) management of anthropogenic impacts (focusing on invasive species, contaminants and protected areas). For each category, we provide an assessment of the current approaches, challenges and future directions. While this is not an exhaustive list of all research needed to address the myriad conservation challenges seabirds face, the results of this effort represent an important synthesis of current expert opinion across sub-disciplines within seabird ecology. As this synthesis highlights, research, in conjunction with direct management, education, and community engagement, can play an important role in facilitating the conservation and management of seabird populations and of the ocean ecosystems on which they and we depend.

El patronatge de les noves oligarquies urbanes a l'art català dels segles XVI i XVII

Al llarg del segle XVI es produí de manera lenta i heterogènia la progressiva introducció al Principat de les formes artístiques del Renaixement italià. Tradicionalment, a Catalunya, igual que a la resta del territori europeu, havia estat la noblesa, com a estament més proper al poder reial, la principal protagonista en el procés de comitència de les obres de més envergadura, moltes d"elles plantejades amb un sentit àulic que pretenia manifestar el predomini polític i econòmic de què havia gaudit d"antuvi aquest segment de la societat. Tanmateix, amb l"arribada a casa nostra dels nous corrents artístics renaixentistes es produí una certa inflexió en aquesta tendència, i hom pot observar com, a la fi del segle XVI i, sobretot, al llarg del segle XVII, aparegueren en l"escena del mercat artístic alts funcionaris reials, magistrats i juristes que, adherits al modern corrent de pensament humanista, dugueren a terme un important exercici de promoció i finançament d"empreses arquitectòniques, escultòriques i pictòriques seguidores dels preceptes renaixentistes. El present estudi analitza en quins termes es produí aquest relleu de patrocini artístic i repassa alguns casos ben emblemàtics.

Fontcuberta i Famadas, Cristina. 'Imatges d'atac. Art i conflicte als segles XVI i XVII'

Durant els darrers anys hem assistit a una ampliació de la perspectiva a través de la qual han estat observades les imatges. Entre els historiadors de l'art, les preguntes tradicionals, centrades en l'autoria o en la seva dimensió estètica, han passat a compartir l'interès amb altres qüestions com ara la del comitent i el seu entorn, la circulació, el mercat o els múltiples usos i significats que aquelles podien adquirir.

Generic features of eighteenth-century American runaway slave advertisements

Pro-gradu –tutkielmani aiheena ovat 1700-luvun ”karanneet orjat” – sanomalehtiilmoitusten genrelle ominaiset piirteet. Tutkimusaineisto koostuu 190 ilmoituksesta, jotka ovat alkuperäisesti ilmestyneet virginialaisissa, pennsylvanialaisissa ja newyorkilaisissa sanomalehdissä 1730-luvulta 1770-luvulle. Tutkimuksen kohteeksi on rajattu ilmoitukset, joissa yksityishenkilöt ilmoittavat orjan/orjien karanneet ja lupaavat kiinniottajalle palkkion. Tutkielman tarkoituksena on tarkastella, millaisia ovat tyypilliset kielelliset piirteet näissä teksteissä ja millainen on prototyyppinen genren edustaja. Genreteorian lisäksi teoriaosuudessa käsittelen jonkin verran 1700- luvun englannin kielen yleisiä piirteitä sekä orjuuden ja sanomalehtien syntyhistoriaa Amerikassa taustoittaakseni tutkimusta. Analyysissa hyödynnän mm. Swalesin ja Bhatian käyttämää käsitettä siirroista (moves). Tutkin ilmoituksien tyypillistä rakennetta jakamalla ne yhdeksään siirtoon, joilla kaikilla on oma tehtävänsä ilmoituksessa. Jotkut siirrot, kuten karkulaisen kuvailu ja palkkion lupaaminen, esiintyvät kaikissa ilmoituksissa, kun taas toiset siirrot ovat läsnä harvemmin. Muita tälle genrelle tyypillisiä ominaisuuksia ovat esim. ilmoituksissa toistuvat kiinteät fraasit ja tietyt sanastolliset erikoisuudet. Lisäksi tutkin ilmoituksissa käytettäviä tapoja viitata asiaan liittyviin henkilöihin, sekä erilaisia toimia, joita ilmoitusten jättäjät ilmoituksien avulla suorittavat. Genressä on havaittavissa pieniä reilun neljänkymmenen vuoden kuluessa tapahtuneita muutoksia, mutta myös eroavaisuuksia eri siirtokuntien ilmoitusten välillä. Yleisesti voidaan todeta, että vaikka ”karanneet orjat” –ilmoitukset voivat vaihdella rakenteeltaan ja sanavalinnoiltaan, suuri osa ilmoituksista seuraa kuitenkin melko prototyyppistä muottia.

Protection of the high-voltage equipment with reduced insulation strength

Power transformer is the most expensive equipment on a substation. It is always necessary to get needed benefit with the lowest expenses. Producing of power transformers with reduced insulation strength is one of the possible ways to reduce expenses. Exploitation of such transformers was begun in the end of 70-th in the last century. Protection from overvoltages was done with valve-type magnetic combined surge arresters with increased blanking voltage during switching overvoltages. Nowadays there is the necessity of replacement of those devices. That’s why modernized nonlinear surge arrester was invented. This master’s thesis is focused on the use research of that modernized device in comparison with usual nonlinear surge arresters. The goal is to show the lightning overvoltages level using different types of nonlinear surge arresters and then calculations of the lightning protection reliability.

Amyloid Beta Precursor Protein: Proper Credit for the Basic Biochemical Properties of the Most Studied Protein in the 21st Century

The amyloid precursor protein (APP) is mainly known for being the precursor of the ß-amyloid peptide, which accumulates in plaques found in the brain of Alzheimer's disease patients. Expression in different tissues and the degree of sequence identity among mammals indicate an essential and non-tissue specific physiological function. APP is anchored to the membrane and displays a single C-terminal intracellular domain and a longer N-terminal extracellular domain. The basic biochemical properties and the scattered data on research, not related to production of beta-amyloid peptide, suggest that the protein and the molecules resulting from APP proteolytic cleavage may act as adhesion factors, enzymes, hormones/neurotransmitters and/or protease inhibitors. APP deserves to be known for its quite notable properties and its physiological role(s).

De Francisco a Marco Antonio Aldana pasando por Gaspar

It is traditionally considered that the «Aldana», whom Gaspar Gil Polo praises at the end of his «Canto de Turia» (1564), was Francisco de Aldana, the «divino». It is nonetheless more probable that it was in fact rather the Valencian poet, Marco Antonio Aldana, almost forgotten today, but very much in the public eye within the cultivated circles of the end of the sixteenth century Valencia

Teodoro Falcón Márquez: El Palacio de las Dueñas y las casas-palacio sevillanas delsiglo XVI.Fundación Aparejadores, Sevilla 2003.

Tal com apunta l'autor en un dels primers apartats del llibre, el lloc preeminent que ocupa el palau de las Dueñas dins el conjunt de les construccions senyorials sevillanes renaixentistes queda evidenciat en el fet que és l'únic d'aquests edificis que és denominat amb el rang de palau; la resta reben la qualificació de cases, indicativa no tant de la menor entitat artística d'aquestes altres mansions, sinó de la importància representativa que adquirí la construcció que ens ocupa, magnificada especialment pel fet que acabà sent propietat de la més distingida de les famílies anomenades «Grandes de España», la casa d'Alba.

La història contemporània de la llengua catalana com a paradoxa

En aquest article ens proposem demostrar que la història del català del segle XVI ençà està caracteritzada per tres fenòmens sense els quals no podem entendre tampoc la situació actual: reculada en els usos socials de la llengua, baixa cohesió de la comunitat lingüística, i augment de la variació interna i les interferències. Aquestes tres constants, però, s'han corregit en part des de finals del XIX, segons l'àmbit i el territori. Al nostre parer, allò que singularitza el català entre les llengües europees és aquesta combinació paradoxal de reculades i recuperacions durant l'edat contemporània. This paper aims to demonstrate that the history of Catalan from the 16th century onwards is characterized by three phenomena without which the current situation of this language cannot be understood. These three phenomena are regression in social practices, low cohesion of the language community and increase of its internal variation as well as interferences. Nevertheless, those phenomena have been partially mitigated from the late 19th century depending on the domain and area concerned. In our view, what singles out Catalan among all European languages is this paradoxical combination of setbacks and recoveries in the late modern age.

The Influence of spanish vihuela and lute music on the development of early seventeenth century english keyboard music as exemplified in the Fitzwilliam virginal book

Digitoitu 29.10 2008.

Perspectives for the Spanish Intervention in Macao in the 19th Century

The purpose of this paper is to analyse some essential events concerning the relationship between Spain and Macao in the middle of the 19th century. Macao remained as a privileged spot for the commercial activities of Spain in China after the opening of the international ports agreed upon in the Treaty of Nanjing in 1842. This encouraged Spanish diplomatic representatives to render special attention to the Portuguese enclave. This became the origin of a shocking proposal for the military conquest of Macao and its surrounding territories by one of these representatives, Sinibaldo de Mas. Although this proposal was never taken under consideration, it helps us to better understand the role Macao played in Spanish strategies in China. Years later, Mas participated as a mediator when the Chinese government attempted to regain sovereignty over Macao by paying an economic compensation to Portugal. The involvement of Sinibaldo de Mas in this project has a strong symbolic meaning, making him a key agent in the relations between Spain and Macao in the 19th century.

Dissertatio academica in Genes. XVI: 13

Dedicatio: Maria Christina Hollberg s. Walin [ruots. pr.], Abrahamus Renström.

The contributions of Henri Victor Regnault in the context of organic chemistry of the first half of the nineteenth century

A very little known aspect of the scientific career of Regnault is his contribution to the emerging organic chemistry in the first half of the nineteenth century. The purpose of this article is not only to describe two of his most important researches in this field, as were the discovery of two series of halogenated derivates of certain organic compounds and the precise identification of some of the then recently discovered alkaloids, but also the main features that identified his research method. With the involvement in these subjects, Regnault unintentionally positioned himself in the midst of some of the polemics about the classification of organic compounds that characterized this age of science.