897 resultados para knowledge based development


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Die 42. Jahrestagung der Gesellschaft für Didaktik der Chemie und Physik (GDCP) wurde im September 2015 an der Humboldt-Universität zu Berlin ausgerichtet. Zum Tagungsthema „Authentizität und Lernen - Das Fach in der Fachdidaktik“ diskutierten neben den Plenarreferentinnen und -referenten eine große Anzahl an Tagungsgästen. Der vorliegende Band umfasst die ausgearbeiteten Beiträge der Teilnehmerinnen und Teilnehmer. (DIPF/Orig.)

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With the evolution of nowadays knowledge-based economies, the labour class becomes more competitive. As a way of getting skills that bring benefits to their careers, university students take advantage of the many opportunities available and go abroad to study. This study develops and empirically tests a structural model that examines the antecedents that influence the decision-making process of an Erasmus student under mobility for studies (EMS) in Aveiro, Coimbra and Porto (2014-2015). Reliability analysis, exploratory factor analysis and linear regressions were used to evaluate the model. Based on a survey with a sample of 872 valid responses, this study has demonstrated that EMS students are also influenced by touristic factors, which gives support to what has recently been approached by other authors. Conclusions and suggestions can be applied by other organizations, mainly Higher Education Institutions in order to attract more EMS students.

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NARVAI, Paulo Capel et al. Validade científi ca de conhecimento epidemiológico gerado com base no estudo Saúde Bucal Brasil 2003. Caderno de saúde pública, Rio de Janeiro, v. 26, n. 4, p. 647-670, abr. 2010.

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The Ingold port adaption of a free beam NIR spectrometer is tailored for optimal bioprocess monitoring and control. The device shows an excellent signal to noise ratio dedicated to a large free aperture and therefore a large sample volume. This can be seen particularly in the batch trajectories which show a high reproducibility. The robust and compact design withstands rough process environments as well as SIP/CIP cycles. Robust free beam NIR process analyzers are indispensable tools within the PAT/QbD framework for realtime process monitoring and control. They enable multiparametric, non-invasive measurements of analyte concentrations and process trajectories. Free beam NIR spectrometers are an ideal tool to define golden batches and process borders in the sense of QbD. Moreover, sophisticated data analysis both quantitative and MSPC yields directly to a far better process understanding. Information can be provided online in easy to interpret graphs which allow the operator to make fast and knowledge-based decisions. This finally leads to higher stability in process operation, better performance and less failed batches.

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O presente Relatório de Estágio tem como objetivo descrever e refletir sobre a Prática de Ensino Supervisionada, no âmbito da unidade curricular de Integração Curricular: Prática Educativa e Relatório de Estágio, inserida no plano de estudos do Mestrado em Ensino do 1.º e 2.º Ciclo do Ensino Básico. A prática desenvolvida reflete o resultado de um percurso de formação desde a Licenciatura em Educação Básica até ao Mestrado, num permanente exercício crítico, reflexivo e investigativo, onde se procurou mobilizar e articular saberes científicos, didáticos e pedagógicos. Assim, descreve-se e reflete-se sobre vivências e experiências desenvolvidas ao longo da prática educativa, atendendo a um quadro teórico e legal e uma análise do contexto e das práticas, que potenciaram o encadeamento e o amadurecimento dos saberes profissionais em estreita relação com os saberes experienciados. No desenvolvimento da prática pedagógica, a metodologia de investigação-ação norteou a conduta do formando ao traduzir-se numa espiral cíclica de observação, planificação, ação e reflexão, cuja dinâmica permite a construção de conhecimentos sólidos que sustentam o desenvolvimento da profissionalidade docente. Neste processo formativo, o formando atribuiu uma especial importância aos momentos de reflexão partilhada com os Professores envolvidos nesta formação, bem como o par pedagógico que permitiram a partilha de saberes e de experiências com reflexos na transformação e melhoramento das práticas. No final deste percurso, consciente do empenho e da determinação aplicados ao longo do percurso formativo, o mestrando evidencia a importância de um ensino com significado e globalizante para o estudante, e que possa dar sentido à expressão “assas para poder voar”.

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Este artigo representa uma tentativa ensaística de elencar 21 temas que, porventura, marcarão o interesse e a investigação no seio da disciplina do comportamento organizacional. Sem pretensões de exaustividade e visando descortinar janelas de oportunidade para investigação, os autores fazem um breve retrato de uma grande diversidade de temas (e.g., ética e responsabilidade social, conciliação do trabalho com a vida familiar, teletrabalho e organizações virtuais, contratos psicológicos da «nova geração», organizações baseadas no conhecimento, globalização e transculturalização, organizações autentizóticas, dignidade humana no trabalho), procurando também gizar as pistas dinâmicas que cada um deles poderá tomar. O panorama traçado procura reflectir as mudanças que as envolventes organizacionais têm vindo a concitar, projectando sobre as organizações e os respectivos decisores um vasto catálogo de desafios, questionamentos e oportunidades – factos e possíveis desenvolvimentos a que os investigadores e estudiosos do CO não devem ficar alheios.

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Each two years the amount of available information in the world double. This is the Information Age, where the success depends on what one knows, not on what one has. A new economy appears with the capacity to generate, to store, to process and to apply effectively the knowledge, based on information, determining the companies productivity and competitiveness.The objective of this work is to understand the information management model of a technological research institute - CTGÁS (Gas Technology Center). The research has been done focused on the 5 main processes and the 15 support processes of the organization value chain , aiming to understand the information management in the organization based on Davenport´s Information Management model (1998). Therefore, it was necessary to identify how the necessary information for the organizational processes accomplishment are determined, obtained, distributed and used by the organization. The research can be classified as descriptive, regarding to its aims, and as a case study, related to the research ways. Interviews with the managers of the organization value chain processes have been carried through, with the objective to identify how they perceive the Information Management process that circulates in the organizational processes. Complementarily, a documentary research has been carried through, associated to the direct observation and procedures and actions follow up, involving the Information Management. The data treatment and analysis have been done from the authors theoretical support and from the managers interviews analysis, documents and processes observed by the researcher in the organization. It was noticed that the organization has raised its level of information needs that are not difficult to be determined and are satisfactorily obtained and distributed, although the majority of them are not structuralized, automatized or even classified regarding to its confidence. These peaces of information have good quality and are important, however they reflect a medium dependence on external and informal information, besides being used only in its great majority for people to know what and how to do something

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O presente relatório transparece o progresso de aprendizagem e reflexão realizado no âmbito da Prática de Ensino Supervisionada em Educação Pré-Escolar e no 1º Ciclo do Ensino Básico. Neste, evidenciou-se uma reflexão da prática educativa que teve como finalidade compreender de que maneira se poderão potenciar as aprendizagens das Ciências Naturais nas crianças. Para tal, destacam-se alguns objetivos que estiveram bastante presentes na dimensão investigativa, tais como a promoção de ambientes de aprendizagem na área das ciências físico-naturais tornando as crianças observadores ativos com competências para investigar, experimentar e aprender; a promoção de contextos de aprendizagem participativa e ativa, desafiadoras e motivantes; o conhecimento e compreensão dos conhecimentos prévios destas, refutando assim a sua expressão e dúvida através do questionamento; e por fim, a promoção de atitudes, competências de ação, competências metodológicas e competências de comunicação nas crianças em relação à aprendizagem de acontecimentos naturais. Assim sendo, a principal finalidade desta investigação-ação nos contextos onde se realizou foi compreender processos associados à (re)construção de conhecimentos com base nos saberes que as crianças já tinham, construindo eu própria saberes profissionais, através da minha própria ação, registada, analisada e fundamentada; ABSTRACT: The following report transpires the progress of learning and reflection that was accomplished within the Supervised Teaching Practice in Preschool Education and in Primary Education. In this, it showed a reflection of educational practice that aimed to understand how it may enhance the learning of Natural Sciences in children. For such, we highlighted a few goals that were very present in the research dimension, such as, promoting learning environments in the area of physical and natural sciences, making children active observers with powers to investigate, experiment and learn; promoting ways of participation and active learning, challenging and motivating; knowledge and understanding of prior knowledge of these, thus disproving your expression and doubt through questioning; and finally, the promotion of attitudes, action skills, methodological skills and communication skills in children with regard to the learning of natural events. Therefore, the main purpose of this research-action, in ways where it was accomplished, was the reconstruction of knowledge based on the awareness that children already contained, building my own professional knowledge, through my own action that were recorded, analyzed and justified.

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Part 7: Cyber-Physical Systems

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Mestrado em Ciências Empresariais

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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Educação, Programa de Pós-Graduação em Educação, 2016.

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El Boletín Tendencia Editorial es un proyecto que nació en 2010 con motivo de la Feria Internacional del Libro de Bogotá para construir y hacer visibles diferentes saberes desde la academia y la edición. Para 2014, el cambio de periodicidad coincidió con uno de los eventos más importantes para la edición universitaria, la Feria Internacional del Libro de Guadalajara donde anualmente se realiza el encuentro de Editores Universitarios Latinoamericanos, el proyecto pasó de su fase nacional a ser pensado en red. Las líneas temáticas traspasan fronteras locales y convocan, en un mismo espacio, las voces de los gestores y especialistas, cuya labor y experiencia permiten cada día mejorar la edición universitaria, lo que posibilita acabar con el mito que concibe a la Universidad como ente ajeno a la sociedad, cuando en realidad esta es la forjadora de líderes, investigadores y emprendedores.

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In 2017, Chronic Respiratory Diseases accounted for almost four million deaths worldwide. Unfortunately, current treatments are not definitive for such diseases. This unmet medical need forces the scientific community to increase efforts in the identification of new therapeutic solutions. PI3K delta plays a key role in mechanisms that promote airway chronic inflammation underlying Asthma and COPD. The first part of this project was dedicated to the identification of novel PI3K delta inhibitors. A first SAR expansion of a Hit, previously identified by a HTS campaign, was carried out. A library of 43 analogues was synthesised taking advantage of an efficient synthetic approach. This allowed the identification of an improved Hit of nanomolar enzymatic potency and moderate selectivity for PI3K delta over other PI3K isoforms. However, this compound exhibited low potency in cell-based assays. Low cellular potency was related to sub optimal phys-chem and ADME properties. The analysis of the X-ray crystal structure of this compound in human PI3K delta guided a second tailored SAR expansion that led to improved cellular potency and solubility. The second part of the thesis was focused on the rational design and synthesis of new macrocyclic Rho-associated protein kinases (ROCKs) inhibitors. Inhibition of these kinases has been associated with vasodilating effects. Therefore, ROCKs could represent attractive targets for the treatment of pulmonary arterial hypertension (PAH). Known ROCK inhibitors suffer from low selectivity across the kinome. The design of macrocyclic inhibitors was considered a promising strategy to obtain improved selectivity. Known inhibitors from literature were evaluated for opportunities of macrocyclization using a knowledge-based approach supported by Computer Aided Drug Design (CADD). The identification of a macrocyclic ROCK inhibitor with enzymatic activity in the low micro molar range against ROCK II represented a promising result that validated this innovative approach in the design of new ROCKs inhibitors.

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In recent years, IoT technology has radically transformed many crucial industrial and service sectors such as healthcare. The multi-facets heterogeneity of the devices and the collected information provides important opportunities to develop innovative systems and services. However, the ubiquitous presence of data silos and the poor semantic interoperability in the IoT landscape constitute a significant obstacle in the pursuit of this goal. Moreover, achieving actionable knowledge from the collected data requires IoT information sources to be analysed using appropriate artificial intelligence techniques such as automated reasoning. In this thesis work, Semantic Web technologies have been investigated as an approach to address both the data integration and reasoning aspect in modern IoT systems. In particular, the contributions presented in this thesis are the following: (1) the IoT Fitness Ontology, an OWL ontology that has been developed in order to overcome the issue of data silos and enable semantic interoperability in the IoT fitness domain; (2) a Linked Open Data web portal for collecting and sharing IoT health datasets with the research community; (3) a novel methodology for embedding knowledge in rule-defined IoT smart home scenarios; and (4) a knowledge-based IoT home automation system that supports a seamless integration of heterogeneous devices and data sources.