Automated Problem Domain Cognition Process in Information Systems Design

An automated cognitive approach for the design of Information Systems is presented. It is supposed to be used at the very beginning of the design process, between the stages of requirements determination and analysis, including the stage of analysis. In the context of the approach used either UML or ERD notations may be used for model representation. The approach provides the opportunity of using natural language text documents as a source of knowledge for automated problem domain model generation. It also simplifies the process of modelling by assisting the human user during the whole period of working upon the model (using UML or ERD notations).

Algorithm BIDIMS for Automated Systematization of Data Array. Case Study: Rediscovering Mendeleev’s Periodic Table of Chemical Elements

The method (algorithm BIDIMS) of multivariate objects display to bidimensional structure in which the sum of differences of objects properties and their nearest neighbors is minimal is being described. The basic regularities on the set of objects at this ordering become evident. Besides, such structures (tables) have high inductive opportunities: many latent properties of objects may be predicted on their coordinates in this table. Opportunities of a method are illustrated on an example of bidimentional ordering of chemical elements. The table received in result practically coincides with the periodic Mendeleev table.

Managing Interval Resources in Automated Planning

In this paper RDPPLan, a model for planning with quantitative resources specified as numerical intervals, is presented. Nearly all existing models of planning with resources require to specify exact values for updating resources modified by actions execution. In other words these models cannot deal with more realistic situations in which the resources quantities are not completely known but are bounded by intervals. The RDPPlan model allow to manage domains more tailored to real world, where preconditions and effects over quantitative resources can be specified by intervals of values, in addition mixed logical/quantitative and pure numerical goals can be posed. RDPPlan is based on non directional search over a planning graph, like DPPlan, from which it derives, it uses propagation rules which have been appropriately extended to the management of resource intervals. The propagation rules extended with resources must verify invariant properties over the planning graph which have been proven by the authors and guarantee the correctness of the approach. An implementation of the RDPPlan model is described with search strategies specifically developed for interval resources.

Codon-precise, synthetic, antibody fragment libraries built using automated hexamer codon additions and validated through next generation sequencing

We have previously described ProxiMAX, a technology that enables the fabrication of precise, combinatorial gene libraries via codon-by-codon saturation mutagenesis. ProxiMAX was originally performed using manual, enzymatic transfer of codons via blunt-end ligation. Here we present Colibra™: an automated, proprietary version of ProxiMAX used specifically for antibody library generation, in which double-codon hexamers are transferred during the saturation cycling process. The reduction in process complexity, resulting library quality and an unprecedented saturation of up to 24 contiguous codons are described. Utility of the method is demonstrated via fabrication of complementarity determining regions (CDR) in antibody fragment libraries and next generation sequencing (NGS) analysis of their quality and diversity.

EPCIS Event-Based traceability in pharmaceutical supply chains via automated generation of linked pedigrees

In this paper we show how event processing over semantically annotated streams of events can be exploited, for implementing tracing and tracking of products in supply chains through the automated generation of linked pedigrees. In our abstraction, events are encoded as spatially and temporally oriented named graphs, while linked pedigrees as RDF datasets are their specific compositions. We propose an algorithm that operates over streams of RDF annotated EPCIS events to generate linked pedigrees. We exemplify our approach using the pharmaceuticals supply chain and show how counterfeit detection is an implicit part of our pedigree generation. Our evaluation results show that for fast moving supply chains, smaller window sizes on event streams provide significantly higher efficiency in the generation of pedigrees as well as enable early counterfeit detection.

Access to Digital Cultural Heritage: Innovative Applications of Automated Metadata Generation

Access to Digital Cultural Heritage: Innovative Applications of Automated Metadata Generation Edited by: Krassimira Ivanova, Milena Dobreva, Peter Stanchev, George Totkov Authors (in order of appearance): Krassimira Ivanova, Peter Stanchev, George Totkov, Kalina Sotirova, Juliana Peneva, Stanislav Ivanov, Rositza Doneva, Emil Hadjikolev, George Vragov, Elena Somova, Evgenia Velikova, Iliya Mitov, Koen Vanhoof, Benoit Depaire, Dimitar Blagoev Reviewer: Prof., Dr. Avram Eskenazi Published by: Plovdiv University Publishing House "Paisii Hilendarski" ISBN: 978-954-423-722-6 2012, Plovdiv, Bulgaria First Edition

Automated Software Reengineering Model and Framework

Тодор П. Чолаков, Димитър Й. Биров - Тази статия представя цялостен модел за автоматизиран реинженеринг на наследени системи. Тя описва в детайли процесите на превод на софтуера и на рефакторинг и степента, до която могат да се автоматизират тези процеси. По отношение на превода на код се представя модел за автоматизирано превеждане на код, съдържащ указатели и работа с адресна аритметика. Също така се дефинира рамка за процеса на реинженеринг и се набелязват възможности за по-нататъшно развитие на концепции, инструменти и алгоритми.

The benefit of combining standard automated perimetry and multifocal visual evoked potential hemifield intersector analysis in suspecious glaucomatous visual field defects

Several analysis protocols have been tested to identify early visual field losses in glaucoma patients using the mfVEP technique, some were successful in detection of field defects, which were comparable to the standard SAP visual field assessment, and others were not very informative and needed more adjustment and research work. In this study we implemented a novel analysis approach and evaluated its validity and whether it could be used effectively for early detection of visual field defects in glaucoma. The purpose of this study is to examine the benefit of adding mfVEP hemifield Intersector analysis protocol to the standard HFA test when there is suspicious glaucomatous visual field loss. 3 groups were tested in this study; normal controls (38 eyes), glaucoma patients (36 eyes) and glaucoma suspect patients (38 eyes). All subjects had a two standard Humphrey visual field HFA test 24-2, optical coherence tomography of the optic nerve head, and a single mfVEP test undertaken in one session. Analysis of the mfVEP results was done using the new analysis protocol; the Hemifield Sector Analysis HSA protocol. The retinal nerve fibre (RNFL) thickness was recorded to identify subjects with suspicious RNFL loss. The hemifield Intersector analysis of mfVEP results showed that signal to noise ratio (SNR) difference between superior and inferior hemifields was statistically significant between the 3 groups (ANOVA p<0.001 with a 95% CI). The difference between superior and inferior hemispheres in all subjects were all statistically significant in the glaucoma patient group 11/11 sectors (t-test p<0.001), partially significant 5/11 in glaucoma suspect group (t-test p<0.01) and no statistical difference between most sectors in normal group (only 1/11 was significant) (t-test p<0.9). Sensitivity and specificity of the HSA protocol in detecting glaucoma was 97% and 86% respectively, while for glaucoma suspect were 89% and 79%. The use of SAP and mfVEP results in subjects with suspicious glaucomatous visual field defects, identified by low RNFL thickness, is beneficial in confirming early visual field defects. The new HSA protocol used in the mfVEP testing can be used to detect glaucomatous visual field defects in both glaucoma and glaucoma suspect patient. Using this protocol in addition to SAP analysis can provide information about focal visual field differences across the horizontal midline, and confirm suspicious field defects. Sensitivity and specificity of the mfVEP test showed very promising results and correlated with other anatomical changes in glaucoma field loss. The Intersector analysis protocol can detect early field changes not detected by standard HFA test.

Cataloguing the Slavonic Manuscript Collection of the Plovdiv Public Library – Problems and MARC 21* Solutions

MARC 21 (‘Machine-Readable Cataloguing’) is a US library standard established worldwide and recently translated also in Bulgarian (those parts used most by librarians in their everyday work). The Bulgarian translations are freely available on the NALIS website (http://www.nalis.bg/) under the Library Standards Section, where also an Online Multilingual Dictionary of MARC 21 Terms can be found. All these works are approved by the US Library of Congress and published on its MARC 21 website under Translations (http://www.loc.gov/marc/translations.html#bulgarian).

Automated Assessment of Student Activity in Moodle

Report published in the Proceedings of the National Conference on "Education and Research in the Information Society", Plovdiv, May, 2014

Automated Data Retrieval in Distance Learning Quality

Report published in the Proceedings of the National Conference on "Education and Research in the Information Society", Plovdiv, May, 2015

Automated Assessment Through Integration of Heterogeneous Systems with a Workflow Engine

Report published in the Proceedings of the National Conference on "Education and Research in the Information Society", Plovdiv, May, 2015

Automated Generating of Test Units for Evaluation of Cognitive and Language Skills

Report published in the Proceedings of the National Conference on "Education and Research in the Information Society", Plovdiv, May, 2016

Factors associated with prompt difficulty in automated essay scoring

This study explores factors related to the prompt difficulty in Automated Essay Scoring. The sample was composed of 6,924 students. For each student, there were 1-4 essays, across 20 different writing prompts, for a total of 20,243 essays. E-rater® v.2 essay scoring engine developed by the Educational Testing Service was used to score the essays. The scoring engine employs a statistical model that incorporates 10 predictors associated with writing characteristics of which 8 were used. The Rasch partial credit analysis was applied to the scores to determine the difficulty levels of prompts. In addition, the scores were used as outcomes in the series of hierarchical linear models (HLM) in which students and prompts constituted the cross-classification levels. This methodology was used to explore the partitioning of the essay score variance.^ The results indicated significant differences in prompt difficulty levels due to genre. Descriptive prompts, as a group, were found to be more difficult than the persuasive prompts. In addition, the essay score variance was partitioned between students and prompts. The amount of the essay score variance that lies between prompts was found to be relatively small (4 to 7 percent). When the essay-level, student-level-and prompt-level predictors were included in the model, it was able to explain almost all variance that lies between prompts. Since in most high-stakes writing assessments only 1-2 prompts per students are used, the essay score variance that lies between prompts represents an undesirable or "noise" variation. Identifying factors associated with this "noise" variance may prove to be important for prompt writing and for constructing Automated Essay Scoring mechanisms for weighting prompt difficulty when assigning essay score.^