Prospective associations between meth/amphetamine (speed) and MDMA (ecstasy) use and depressive symptoms in secondary school students

Background Research has raised significant concern regarding the affective consequences of synthetic drug use. However, little evidence from well-controlled longitudinal studies exists on these consequences. The aim of this study was to determine whether use of meth/amphetamine (speed) and 63,4- methylenedioxymethamphetamine (MDMA, ecstasy) is independently predictive of subsequent depressive symptoms in adolescents. Methods A sample of 3880 adolescents from secondary schools in disadvantaged areas of Quebec, Canada, were followed over time (2003e2008). Logistic regression was used to test the association between meth/ amphetamine and MDMA use in grade 10 (ages 15e16 years) and elevated depressive symptoms on an abridged Center for Epidemiologic Studies-Depression scale in grade 11, controlling for pre-existing individual and contextual characteristics. Results After adjustment, both MDMA use (OR 1.7, 95% CI 1.1 to 2.6) and meth/amphetamine use (OR 1.6, 95% CI 1.1 to 2.3) in grade 10 significantly increased the odds of elevated depressive symptoms in grade 11. These relationships did not vary by gender or pre-existing depressive symptoms. Increased risk was particularly observed in concurrent usage (OR 1.9, 95% CI 1.2 to 2.9). Conclusions Adolescent use of meth/amphetamine and MDMA (particularly concurrent use) is independently associated with subsequent depressive symptoms. Further enquiry must determine whether these associations reflect drug-induced neurotoxicity and whether adolescence is a period of increased vulnerability to the hazards of synthetic drug exposure.

Averiguação da articulação entre os documentos que regulam a prática pedagógica e a avaliação externa, no 1.º Ciclo, no que refere à escrita

Relatório de estágio apresentado para a obtenção do grau de Mestre - Especialização de pré-Escolar e 1º ciclo de ensino

Prospective associations between meth/amphetamine (speed) and MDMA (ecstasy) use and depressive symptoms in secondary school students

Background Research has raised significant concern regarding the affective consequences of synthetic drug use. However, little evidence from well-controlled longitudinal studies exists on these consequences. The aim of this study was to determine whether use of meth/amphetamine (speed) and 63,4- methylenedioxymethamphetamine (MDMA, ecstasy) is independently predictive of subsequent depressive symptoms in adolescents. Methods A sample of 3880 adolescents from secondary schools in disadvantaged areas of Quebec, Canada, were followed over time (2003e2008). Logistic regression was used to test the association between meth/ amphetamine and MDMA use in grade 10 (ages 15e16 years) and elevated depressive symptoms on an abridged Center for Epidemiologic Studies-Depression scale in grade 11, controlling for pre-existing individual and contextual characteristics. Results After adjustment, both MDMA use (OR 1.7, 95% CI 1.1 to 2.6) and meth/amphetamine use (OR 1.6, 95% CI 1.1 to 2.3) in grade 10 significantly increased the odds of elevated depressive symptoms in grade 11. These relationships did not vary by gender or pre-existing depressive symptoms. Increased risk was particularly observed in concurrent usage (OR 1.9, 95% CI 1.2 to 2.9). Conclusions Adolescent use of meth/amphetamine and MDMA (particularly concurrent use) is independently associated with subsequent depressive symptoms. Further enquiry must determine whether these associations reflect drug-induced neurotoxicity and whether adolescence is a period of increased vulnerability to the hazards of synthetic drug exposure.

Second location for Dental School 1877

One of the four original buildings on campus, located on South University east of the Presidents' house, where Clements Libary now stands. Used as Professor's house from 1840 to 1877 and as the Dental College from 1877 to 1891. East wing added in 1878. In 1891, the Dental School moved, the building was enlarged to the north, a third story was added, the entrance changed to the west, and "Engineering" placed over the door. Used by Engineeering from 1891 to 1922. After 1904 it was called "Old Engineering Building." Demolished in 1922. On verso: Photographed in 1887 by A.L. Colton, '89

Dental School - S. side of Campus

One of the four original buildings on campus, located on South University east of the Presidents' house, where Clements Libary now stands. Used as Professor's house from 1840 to 1877 and as the Dental College from 1877 to 1891. East wing added in 1878. In 1891, the Dental School moved, the building was enlarged to the north, a third story was added, the entrance changed to the west, and "Engineering" placed over the door. Used by Engineeering from 1891 to 1922. After 1904 it was called "Old Engineering Building." Demolished in 1922.

Identification and feasibility test of specialized rural pedestrian safety training. Volume 3: PEDSAFE junior/senior high school materials. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Pest control in the school environment : adopting integrated pest management.

Mode of access: Internet.

Safe Performance Secondary School Driver Education Curriculum Demonstration Project. Annual report.

National Highway Traffic Safety Administration, Office of Driver and Pedestrian Programs, Washington, D.C.

Impact of discontinuing Idaho's periodic motor vehicle inspection program (a before and after outage rate study).

Mode of access: Internet.

The American vegetable practice, or, A new and improved guide to health. : Designed for the use of families. : In six parts. Part I. Concise view of the human body, with engraved and wood-cut illustrations. Part II. Glance at the old school practice of physic. Part III. Vegetable materia medica, with colored illustrations. Part IV. Compounds. Part V. Practice of medicine, based upon what are deemed correct physiological and pathological principles. Part VI. Guide for women, containing a simplified treatise on childbirth, with a description of the diseases peculiar to females and infants. /

Errata and advertisement for "New England Depot. D.L. Hale" at end of v. 2.

Preventing school violence : plenary papers of the 1999 Conference on Criminal Justice Research and Evaluation /

"May 2000."

Annual report of the managing committee of the American school of classical studies at Athens.

Archaeological institute of America.

Phase I: developing generalized driving while intoxicated (DWI) school curricula. Interim report.

National Highway Traffic Safety Administration, Washington, D.C.

Analysis of the drinking driving attitudes of New Hampshire high school students. Second survey. Final report.

National Highway Traffic Safety Administration, Office of Driver and Pedestrian Programs, Washington, D.C.

Juvenile court alcohol school evaluation. Interim report, September 1, 1977.

National Highway Traffic Safety Administration, Washington, D.C.