The effect of Rh particle size on the catalytic performance of porous silica supported rhodium catalysts for CO hydrogenation

Silica-supported Rh catalysts with different Rh particle dimensions were investigated for CO hydrogenation. The catalysts were characterized by various techniques such as TEM, H-2-TPR and N-2 adsorption to study the catalyst morphology, the size distributions of Rh particles and the silica pores. It was found that the distribution and the size of Rh particles were affected by the silica pores, and the metal grains were enclosed in the pores of the support, and thereby their growth was limited. The catalytic activity and selectivity to C-2-oxygenates for CO hydrogenation were found to be significantly controlled by the Rh particle sizes, and the higher activity and selectivity to C2-oxygenates were obtained over bigger Rh particles, within the range of the reported particle sizes.

Identificação molecular de nematóides de galhas, Meloidogyne spp.

2008

Aspectos gerais sobre nematóides das lesões radiculares (gênero Pratylenchus).

2008

Levantamento semidetalhado dos solos da microbacia do Córrego do Pito Aceso, Município de Bom Jardim, região serrana do Estado do Rio de Janeiro - RJ.

O objetivo do presente estudo foi realizar o levantamento semidetalhado de solos, na escala 1:10.000, da microbacia do córrego Pito Aceso, com aproximadamente 500 ha, inserida no distrito de Barra Alegre, município de Bom Jardim. Os procedimentos utilizados envolveram a geração de um banco dados digital, manipulação de produtos de sensoriamento remoto (imagens GeoEye) e a confecção de um modelo digital de elevação (MDE), buscando otimizar o mapeamento de solos no campo e facilitar a geração de mapas interpretativos úteis ao planejamento da área. As feições das pedopaisagens foram separadas e representadas por unidades de mapeamento e, definidas em função das classes de solo, condição de drenagem, vegetação original, relevo e material de origem. Nas áreas de várzeas, relacionadas aos sedimentos recentes do Quaternário, ocorrem os Gleissolos Háplicos. Já nas áreas elevadas, relacionadas com as litologias da Unidade Imbé do complexo Rio Negro foram identificados Argissolos, Cambissolos, Latossolos e Neossolos Litólicos, estes ocorrendo associados com Afloramentos de Rochas. Os resultados demonstraram que a utilização do modelo digital de elevação e de seus atributos do terreno derivados foram úteis na otimização dos trabalhos de campo e na delimitação das unidades de mapeamento, aumentando a precisão do mapa final, e contribuindo, assim, para a elaboração do plano de manejo conservacionista da microbacia.

The lack of associations between alleles at the hypoxia-Inducible factor 1A C1772T loci and responses to acute hypoxia.

Objective The aim of this study was to investigate the associations between alleles of the hypoxia-inducible factor 1A (HIF1A) C1772T polymorphism and several physiological responses to hypoxia, including the hypoxic ventilatory response (HVR), and serum erythropoietin (EPO), arterial oxygen saturation (Sao2), and acute mountain sickness (AMS) responses during 8 hours of exposure to normobaric hypoxia. Methods A total of 76 males participated in the study; 52 participants completed an 8-hour exposure to 12.7% oxygen, during which time Sao2, EPO concentrations, and AMS scores were measured, while 62 individuals took part in an HVR trial (in total 38 individuals completed both protocols). DNA was obtained from leukocytes, and a 346-bp fragment of the HIF1A gene containing the C1772T polymorphism was amplified using polymerase chain reaction. Fragments were sequenced to reveal individual genotypes, and the associations between HIF1A genotype and EPO, Sao2, AMS responses to hypoxia and HVR were examined. Results The magnitude of the hypoxic responses was highly variable between individuals. The increase in participants' EPO responses ranged from 89% to 388% of baseline values following hypoxia, while Sao2 values during the exposure ranged from 71% to 89%. The HVR ranged from −0.04 to +2.18 L · min−1 · Sao2%−1 among participants. No significant differences in EPO, Sao2, AMS, or HVR results were observed between the HIF1A CC genotype and the combined CT/TT genotype group. Conclusion In this study, the HIF1A C1772T polymorphism does not appear to influence EPO, Sao2, or AMS responses during acute hypoxic exposure, or the magnitude of the HVR.

Evaluating SWICE-R (South West Information for Clinical Effectiveness - Rural). Final report for South West Workforce Development Confederations (Knowledge Resources Development Unit)

Yeoman, A., Durbin, J. & Urquhart, C. (2004). Evaluating SWICE-R (South West Information for Clinical Effectiveness - Rural). Final report for South West Workforce Development Confederations, (Knowledge Resources Development Unit). Aberystwyth: Department of Information Studies, University of Wales Aberystwyth. Sponsorship: South West WDCs (NHS)

Taking advantage of an old concept, "illegitimate transcription", for a proposed novel method of genetic diagnosis of McArdle disease

McArdle disease is a metabolic disorder caused by pathogenic mutations in the PYGM gene. Timely diagnosis can sometimes be difficult with direct genomic analysis, which requires additional studies of cDNA from muscle transcripts. Although the "nonsense-mediated mRNA decay" (NMD) eliminates tissue-specific aberrant transcripts, there is some residual transcription of tissue-specific genes in virtually all cells, such as peripheral blood mononuclear cells (PBMCs).We studied a subset of the main types of PYGM mutations (deletions, missense, nonsense, silent, or splicing mutations) in cDNA from easily accessible cells (PBMCs) in 12 McArdle patients.Analysis of cDNA from PBMCs allowed detection of all mutations. Importantly, the effects of mutations with unknown pathogenicity (silent and splicing mutations) were characterized in PBMCs. Because the NMD mechanism does not seem to operate in nonspecific cells, PBMCs were more suitable than muscle biopsies for detecting the pathogenicity of some PYGM mutations, notably the silent mutation c.645G>A (p.K215=), whose effect in the splicing of intron 6 was unnoticed in previous muscle transcriptomic studies.We propose considering the use of PBMCs for detecting mutations that are thought to cause McArdle disease, particularly for studying their actual pathogenicity.

A fully integrated multi-channel detector for electron spectroscopy

Langstaff, David; Bushell, A.; Chase, T.; Evans, D.A., (2005) 'A fully integrated multi-channel detector for electron spectroscopy', Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 238 pp.219-223 RAE2008 Synchrotron Radiation in Materials Science ? Proceedings of the 4th Conference on Synchrotron Radiation in Materials Science 4th Conference on Synchrotron Radiation in Materials Science

Absence of turnover and futile cycling of sucrose in leaves of Lolium temulentum L.: implications for metabolic compartmentation

Cairns, A. J., Gallagher, J. A. (2004). Absence of turnover and futile cycling of sucrose in leaves of Lolium temulentum L.: implications for metabolic compartmentation. Planta, 219 (5), 836-846. Sponsorship: BBSRC RAE2008

Robert Heinich, Michael Molenda, James D. Russell, Sharon E. Smaldino, Instructional Media and Technologies for Learning, Prentice-Hall, Inc., Englewood Cliffs, New Jersey 1996, ss. 446. Steven Hackbarth, The Educational Technology Handbook. A Comprehensive Guide, Educational Technology Publications Inc., Englewood Cliffs, New Jersey 1996, ss. 351

Recenzje i sprawozdania z książek

Geomorfologiczne uwarunkowania rozwoju sieci komunikacyjnej na obszarze młodoglacjalnym (zlewnia Perznicy, Pojezierze Drawskie

The aim of the studies in the Perznica River catchment were relief changes caused by the development of transportation infrastructure. This type of transformation is dependable on the state of economy and the settlements. The development of transportation network in the last two hundred years was examined through the analysis of archival cartographic materials – maps from the years 1789, 1855, 1877, 1935 – and the comparison with the situation from mid 1980s. The Perznica River catchment has an area of 249 km2 and it is located in north-western Poland in the central part of the Drawskie Lakeland macroregion, which belongs to the West Pomeranian Lakeland. The heterogeneous Perznica River catchment relief has a denivelation of 159 m and is within 60 and 219 m a.s.l. The study area is within the Parsęta River lobe. A number of subzones, whose morphological diversity and diversity of sediments lithofacies is mainly a reflection of areal deglaciation of the continental ice-sheet marginal zone, has been distinguished and these are: • subzone of the internal kame moraine – the undulated moraine upland, diversified by kame forms and kettle holes, • subzone of ice-free space forms – the uplands of kame plateaux, • subzone of melt-out lake basins – Lake Wielatowo basin with a characteristic collar ridge, • morphological levels of the northern Pomeranian sloping surface – mainly flat moraine uplands and small outwashes. The economic development of the Perznica River catchment advanced in close connection with the physical and geographical context, mainly with the relief, soils and hydrological conditions. As a result, the flat moraine uplands and marginal outflow plains, which were easiest to cultivate, have been developed and populated faster than any other. Since the early medieval period, large, compact villages, often centered around big estates, were emerging in those areas. In areas with a high relief energy–kame-melt moraines, ice-free space forms and ridges around melt-out lake basins–farming entered on a larger scale from the eighteenth century. Scattered settlements in those areas forced the creation of a dense access road network to farms and fields. In the case of anthropogenic forms of transportation with denivelation exceeding 1 m in the study area, road excavations are present for 37.3 km, road undercuttings for 43.8 km and road embankments for 38.7 km in total length. That gives a high ratio of density of such forms, equal to 2.1 km per km–2.

O naruszaniu podstawowych zasad postępowania naukowego. “Wzgórze przeznaczenia archeologii” górą skandalu

„We are paying a high price for the increasingly unequivocal equation drawn between knowledge and science and ordinary market product. The ideal of perfectly unrestrained cognition, the true mother of science, is threatened by the mass drive towards practical use and application of knowledge, a looming departure into nothingness. Politicians and managers of scientific life are guilty of considerable contribution in corrupting respectable university structures, and thus undermining culture of science and scholarly ethics. (…). Acquisition of funds, sponsorship, media presence, popularisation or even striving for commercial gain are recognised by politicians and scientific consultants, but most of all they are accepted by the university management as objectives worthy of effort, not to say the foremost goals of science. University rectors are nowadays interested primarily in the amounts of acquired moneys. The outcomes of research thus financed is subject to virtually no control, nor does it arouse any interest, unless it turns out to be fit to be announced in the media as a sensation, thereby serving the ‘prestige’ of the university”.

Productos tradicionales y de innovación en diseño decorados con barniz de Pasto Mopa-Mopa.

36 hojas : ilustraciones, fotografías a color

Evaluation of microbial adjuncts and their effect on the ripening of cheddar cheese

A bacteriocin-producing strain of Lactobacillus paracasei DPC 4715 was used as an adjunct culture in Cheddar cheese in order to control the growth of “wild” nonstarter lactic acid bacteria. No suppression of growth of the indicator strain was observed in the experimental cheese. The bacteriocin produced by Lactobacillus paracasei DPC 4715 was sensitive to chymosin and cathepsin D and it may have been cleaved by the rennet used for the cheese manufactured or by indigenous milk proteases. A series of studies were performed using various microbial adjuncts to influence cheese ripening. Microbacterium casei DPC 5281, Corynebacterium casei DPC 5293 and Corynebacterium variabile DPC 5305 were added to the cheesemilk at level of 109 cfu/ml resulting in a final concentration of 108 cfu/g in Cheddar cheese. The strains significantly increased the level of pH 4.6-soluble nitrogen, total free amino acids after 60 and 180 d of ripening and some individual free amino acids after 180 d. Yarrowia lipolytica DPC 6266, Yarrowia lipolytica DPC 6268 and Candida intermedia DPC 6271 were used to accelerate the ripening of Cheddar cheese. Strains were grown in YG broth to a final concentration of 107 cfu/ml, microfluidized, freeze-dried and added to the curd during salting at level of 2% w/w. The yeasts positively affected the primary, secondary proteolysis and lipolysis of cheeses and had aminopeptidase, dipeptidase, esterase and 5’ phosphodiestere activities that contributed to accelerate the ripening and improve the flavor of cheese. Hafia alvei was added to Cheddar cheesemilk at levels of 107 cfu/ml and 108 cfu/ml and its contribution during ripening was evaluated. The strain significantly increased the level of pH 4.6-soluble nitrogen, total free amino-acids, and some individual free amino-acids of Cheddar cheese, whereas no differences in the urea-polyacrylamide gel electrophoresis (urea-PAGE) electrophoretograms of the cheeses were detected. Hafia alvei also significantly increased the level of some biogenic amines. A low-fat Cheddar cheese was made with Bifidobacterium animalis subsp. lactis, strain BB-12® at level of 108 cfu/ml, as a probiotic adjunct culture and Hi-Maize® 260 (resistant high amylose maize starch) at level of 2% and 4% w/v, as a prebiotic fiber which also played the role of fat replacer. Bifidobacterium BB-12 decreased by 1 log cycle after 60 d of ripening and remained steady at level of ~107 cfu/g during ripening. The Young’s modulus also increased proportionally with increasing levels of Hi-maize. Hencky strain at fracture decreased over ripening and increased with increasing in fat replacer. A cheese based medium (CBM) was developed with the purpose of mimicking the cheese environment at an early ripening stage. The strains grown in CBM showed aminopeptidase activity against Gly-, Arg-, Pro- and Phe-p-nitroanalide, whereas, when grown in MRS they were active against all the substrates tested. Both Lb. danicus strains grown in MRS and in CBM had aminotransferase activity towards aromatic amino acids (Phe and Trp) and also branched-chain amino acids (Leu and Val). Esterase activity was expressed against p-nitrophenyl-acetate (C2), pnitrophenyl- butyrate (C4) and p-nitrophenyl-palmitate (C16) and was significantly higher in CBM than in MRS.

An investigation on the use of SNR distributions for the optimisation of coarse-fine spectrum sensing for cognitive radio

This thesis investigates the optimisation of Coarse-Fine (CF) spectrum sensing architectures under a distribution of SNRs for Dynamic Spectrum Access (DSA). Three different detector architectures are investigated: the Coarse-Sorting Fine Detector (CSFD), the Coarse-Deciding Fine Detector (CDFD) and the Hybrid Coarse-Fine Detector (HCFD). To date, the majority of the work on coarse-fine spectrum sensing for cognitive radio has focused on a single value for the SNR. This approach overlooks the key advantage that CF sensing has to offer, namely that high powered signals can be easily detected without extra signal processing. By considering a range of SNR values, the detector can be optimised more effectively and greater performance gains realised. This work considers the optimisation of CF spectrum sensing schemes where the security and performance are treated separately. Instead of optimising system performance at a single, constant, low SNR value, the system instead is optimised for the average operating conditions. The security is still provided such that at the low SNR values the safety specifications are met. By decoupling the security and performance, the system’s average performance increases whilst maintaining the protection of licensed users from harmful interference. The different architectures considered in this thesis are investigated in theory, simulation and physical implementation to provide a complete overview of the performance of each system. This thesis provides a method for estimating SNR distributions which is quick, accurate and relatively low cost. The CSFD is modelled and the characteristic equations are found for the CDFD scheme. The HCFD is introduced and optimisation schemes for all three architectures are proposed. Finally, using the Implementing Radio In Software (IRIS) test-bed to confirm simulation results, CF spectrum sensing is shown to be significantly quicker than naive methods, whilst still meeting the required interference probability rates and not requiring substantial receiver complexity increases.