Desarrollo de la zona costera: desarrollo y medio ambiente del Caribe en los aspectos costero y marítimo: programas y actividades posibles = Coastal area development: development and environment in the Caribbean coastal and marine aspects: possible programmes and activities

Incluye Bibliografía

Some possible implications for CDCC member countries of recent global and regional developments

Includes bibliography

Algunas reflexiones sobre los censos del 90: posibles áreas de colaboración = Some thoughts concerning the 1990 censuses: possible areas for co-operation

Incluye Bibliografía

Informe de la Reunión sobre Crisis Externa: Proceso de Ajuste y su Impacto Inmediato y de Largo Plazo en el Desarrollo Social. ¿Qué Hacer? = Report of the Meeting on Possible Measures to deal with the Immediate and Long-Term Impact on Social Development of the External Crisis and the Adjustment Process

Informe de la reunión que tuvo por objetivo: 1) considerar estrategias y propuestas de acción para superar la pobreza y lograr un desarrollo social armónico con el desarrollo económico; y 2) promover un análisis de la situación del desarrollo social en la región, y específicamente de la naturaleza y características de la pobreza en el marco de los factores estructurales y de los factores derivados del proceso de ajuste a la crisis externa.

QCD sum rule study for a possible charmed pentaquark Θ c(3250)

We use QCD sum rules to study the possible existence of a Θc(3250) charmed pentaquark. We consider the contributions of condensates up to dimension 12 and work at leading order in αs. We obtain mΘc=(3.29±0.13) GeV, compatible with the mass of the structure seen by BABAR Collaboration in the decay channel B-→p̄Σc++π-π-. The proposed state is compatible with a previous proposed pentaquark state in the anticharmed sector. © 2013 American Physical Society.

Genetic diversity of the HLA-G coding region in Amerindian populations from the Brazilian Amazon: a possible role of natural selection

HLA-G has an important role in the modulation of the maternal immune system during pregnancy, and evidence that balancing selection acts in the promoter and 3′UTR regions has been previously reported. To determine whether selection acts on the HLA-G coding region in the Amazon Rainforest, exons 2, 3 and 4 were analyzed in a sample of 142 Amerindians from nine villages of five isolated tribes that inhabit the Central Amazon. Six previously described single-nucleotide polymorphisms (SNPs) were identified and the Expectation-Maximization (EM) and PHASE algorithms were used to computationally reconstruct SNP haplotypes (HLA-G alleles). A new HLA-G allele, which originated in Amerindian populations by a crossing-over event between two widespread HLA-G alleles, was identified in 18 individuals. Neutrality tests evidenced that natural selection has a complex part in the HLA-G coding region. Although balancing selection is the type of selection that shapes variability at a local level (Native American populations), we have also shown that purifying selection may occur on a worldwide scale. Moreover, the balancing selection does not seem to act on the coding region as strongly as it acts on the flanking regulatory regions, and such coding signature may actually reflect a hitchhiking effect.Genes and Immunity advance online publication, 3 October 2013; doi:10.1038/gene.2013.47.

Influence of experimental canine ehrlichiosis on the E-ADA activity and purine levels in serum and possible functional correlations with pathogenesis

The aim of this study was to evaluate adenosine deaminase activity and purines levels in serum of dogs experimentally infected by Ehrlichia canis. Banked serum samples of dogs divided into two groups with five animals each: healthy animals and animals infected by E. canis. The concentration of purines (adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), adenosine, inosine, hypoxanthine, xanthine and uric acid), and adenosine deaminase (E-ADA) activity in sera were evaluated. Samples were collected on days 12 and 30 post-infection (PI). The E-ADA activity showed a significant reduction on day 12 PI, and increased on day 30 PI in dogs infected with E. canis. On day 12, an increase in seric concentration of ATP, ADP and adenosine was verified, and different levels of hypoxanthine, xanthine and uric acid had a drastic reduction in infected compared healthy dogs (P< 0.05). However, on day 30 PI, the levels of seric ADP and AMP decreased, unlike the concentration of xanthine and uric acid that increased significantly in infected dogs (P< 0.05). Therefore, the activity of E-ADA and purine levels are altered in experimental canine ehrlichiosis, probably with the purpose of modulating the pathogenesis of the disease related to immune response, oxidative stress and coagulation disorders in acute phase. © 2013 Elsevier B.V.

Los posibles cambios climáticos en América Latina y el Caribe y sus consecuencias = Possible climatic changes in Latin America and the Caribbean and their consequences

Incluye Bibliografía

Principales objetivos y posibles características de una unión de pagos latinoamericana: redacción provisional = Main objectives and possible characteristics of a Latin American payments union: provisional draft

Incluye Bibliografía