984 resultados para Stimson, Hiram K., b. 1804


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A blueprint produced by Westinghouse Electric & MFG. Co. in Pittsburgh, Pennsylvanna. The blueprint is dated 19 August 1903 and is stamped "OBSOLETE".

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Tesis (Doctorado en Ciencias con Acentuación en Química de Productos Naturales) UANL, 2012.

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Comunicaci??n presentada en las Jornadas sobre Investigaci??n e Innovaci??n en la Educaci??n F??sica escolar celebradas en el CEP de La Laguna, del 2 al 5 de junio de 2010

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We evaluate the non-resonant decay amplitude of the process B(+/-) -> K(+/-)pi(+)pi(-) using an approach based on final state hadronic interactions described in terms of meson exchanges. We conclude that this mechanism generates inhomogeneities in the Dalitz plot of the B decay. (C) 2008 Published by Elsevier B.V.

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The inhibition of human cysteine cathepsins B, L, S and K was evaluated by a set of hypervalent tellurium compounds (telluranes) comprising both organic and inorganic derivatives. All telluranes studied showed a time-and concentration-dependent irreversible inhibition of the cathepsins, and their second-order inactivation rate constants were determined. The organic derivatives were potent inhibitors of the cathepsins and clear specificities were detected, which were parallel to their known substrate specificities. In all cases, the activity of the tellurane-inhibited cathepsins was recovered by treatment of the inactivated enzymes with reducing agents. The maximum stoichiometry of the reaction between cysteine residues and telluranes were also determined. The presented data indicate that it is possible to design organic compounds with a tellurium(IV) moiety as a novel warhead that covalently modifies the catalytic cysteine, and which also form strong interactions with subsites of cathepsins B, L, S and K, resulting in more specific inhibition.

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O objetivo deste experimento foi determinar a qualidade e o valor nutritivo de silagens do subproduto da pupunha, produzidas com aditivos, conforme os tratamentos: T1 - Testemunha (sem aditivo); T2 - Adição de 2,5% de açúcar; T3 - Adição de 10,0% de polpa cítrica e T4 - Adição de 10,0% de milho moído, base da matéria natural. Verificou-se que a adição 10% de polpa cítrica (PC) ou milho moído (MM) elevou o teor de matéria seca da massa a ser ensilada, bem como da silagem, em 6,5 e 8,0 unidades percentuais, respectivamente. Silagens com aditivos apresentaram menores valores de nitrogênio amoniacal (N-NH3 / NT) e pH. O consumo de matéria seca foi maior para as silagens feitas com PC ou MM, atingindo 85 g/kg PV0,75 ou 2,1% do PV, contra 44,7 g/kgPV0,75 ou 1,12%, para as silagens sem aditivo ou com 2,5% de açúcar. O coeficiente de digestibilidade aparente da matéria seca, tambm foi superior para as silagens contendo 10% de PC ou MM (65,0%) em relação à média das demais (52,0%). A digestibilidade da parede celular não mostrou tendência definida em função dos tratamentos. A silagem de subproduto da pupunha feita com a adição de 10% de polpa cítrica ou milho moído, apresentou valor nutritivo semelhante às silagens de forrageiras convencionais.

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Objetivando auxiliar trabalhos taxonômicos e farmacobotânicos, foram realizados estudos morfoanatômicos dos órgãos vegetativos de Piper crassinervium H.B. & K. (jaborandi). O material foi analisado seguindo-se técnicas usuais de corte e coloração. P. crassinervium é um arbusto de caule ereto, de folhas estipuladas e alternas. Dentre as características anatômicas importantes para a sua identificação destacam-se: parênquima cortical radical com esclereídes; córtex caulinar com faixas descontínuas de colênquima e tecido vascular organizado em dois círculos descontínuos de feixes colaterais, delimitados por endoderme com estrias de Caspary; folha dorsiventral, hipoestomática, com estômatos ciclocíticos e tetracíticos e hipoderme unisseriada, porém, com 1-3 camadas de células na região da nervura principal; parênquima clorofiliano com idioblastos oleíferos; tricomas glandulares na epiderme unisseriada e idioblastos com pequenos cristais aciculares no parênquima em todos os órgãos.

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We studied the development of the insulin secretion mechanism in the pancreas of fetal (19- and 21-day-old), neonatal (3-day-old), and adult (90-day-old) rats in response to stimulation with 8.3 or 16.7 mM glucose, 30 mM K+, 5 mM theophylline (Theo) and 200 µM carbamylcholine (Cch). No effect of glucose or high K+ was observed on the pancreas from 19-day-old fetuses, whereas Theo and Cch significantly increased insulin secretion at this age (82 and 127% above basal levels, respectively). High K+ also failed to alter the insulin secretion in the pancreas from 21-day-old fetuses, whereas 8.3 mM and 16.7 mM glucose significantly stimulated insulin release by 41 and 54% above basal levels, respectively. Similar results were obtained with Theo and Cch. A more marked effect of glucose on insulin secretion was observed in the pancreas of 3-day-old rats, reaching 84 and 179% above basal levels with 8.3 mM and 16.7 mM glucose, respectively. At this age, both Theo and Cch increased insulin secretion to close to two-times basal levels. In islets from adult rats, 8.3 mM and 16.7 mM glucose, Theo, and Cch increased the insulin release by 104, 193, 318 and 396% above basal levels, respectively. These data indicate that pancreatic B-cells from 19-day-old fetuses were already sensitive to stimuli that use either cAMP or IP3 and DAG as second messengers, but insensitive to stimuli such as glucose and high K+ that induce membrane depolarization. The greater effect of glucose on insulin secretion during the neonatal period indicates that this period is crucial for the maturation of the glucose-sensing mechanism in B-cells.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The Concentrations of C, N and P were determined in the internodes of the stem of Echinochloa polystachya (H.B.K.) Hitchcock with the aim of showing their longitudinal distributions. The concentrations ranged from 421.93 to 466.03 mgCgDW-1; from 2.78 to 13.61 mg N gDW-1 and from 0.151 to 1.074 mg P gDW-1. N and P concentrations increased towards the apical direction of the stem. C concentrations showed an inverse trend. These distributions suggest that N and P are transported to the apical region of the stem, while the majority of the C compounds observed in the distal region must be retained in the supporting structure of the plant.