The works of Benjamin Disraeli, earl of Beaconsfield, embracing novels, romances, plays, poems, biography, short stories and great speeches : with a critical introduction /

Title within ornamental border in gold and colors.

Tanaham sogûi ttûigôun yôljông (Une passion brûlante contenue dans une beauté sobre)

National audience

The sources of Luke's passion-narrative /

Published also as thesis, University of Chicago.

Cyanogenic compounds from mesocarp and epicarp flours of passion fruit (passiflora edulis flavicarpa).

2016

Water risk contamination trends by yellow-passion fruit pesticides in a small catchment in the eastern Amazon.

2009

Food and passion: technologies of self transformation in Jamie’s kitchen

Since the 1990s there has been a surge of televisual dramatisations of real-life cooking shows in industrialised countries (Versteegan 2010: 447). Through reality television cooking shows such as, MasterChef, Jamie 's Kitchen, Hell's Kitchen, viewers have encountered celebrity chefs, 'foodies', hospitality trainees, contestants, cooking competitions and customers. These shows have been understood as an indication of- and intervention into - contemporary consumption trends and as vehicles for social change. Many reality-based cooking shows have been regarded as educational, pedagogical sites that 'encourage populations to undertake surveillance of their own and others' bodies' and eating habits with messages like: 'You are what you eat!' or 'Organic is better' (Rich 2011: 3; see also Lewis 2007 and Chapter 4 in this book by Szkupinski-Quiroga, Sandlin and Redmon Wright).In this chapter we explore the reality television programme Jamie's Kitchen as a pedagogical site which seeks to transform young people's understandings about food, work and ultimately themselves. In 2002 the high-profile celebrity chef Jamie Oliver set out to transform a group of unemployed young Londoners into the enterprising, ideal workers of twenty-first century, :flexible capitalism.1 This process of transformation was represented in the enormously successful Channel 4 TV series Jamie's Kitchen.2 In Australia, we viewed the series, as it was screened on Channel 10 over five weeks during July and August 2003.

Inhibition of HDAC3- and HDAC6-promoted survivin expression plays an important role in SAHA-induced autophagy and viability reduction in breast cancer cells

SAHA is a class I HDAC/HDAC6 co-inhibitor and an autophagy inducer currently undergoing clinical investigations in breast cancer patients. However, the molecular mechanism of action of SAHA in breast cancer cells remains unclear. In this study, we found that SAHA is equally effective in targeting cells of different breast cancer subtypes and tamoxifen sensitivity. Importantly, we found that down-regulation of survivin plays an important role in SAHA-induced autophagy and cell viability reduction in human breast cancer cells. SAHA decreased survivin and XIAP gene transcription, induced survivin protein acetylation and early nuclear translocation in MCF7 and MDA-MB-231 breast cancer cells. It also reduced survivin and XIAP protein stability in part through modulating the expression and activation of the 26S proteasome and heat-shock protein 90. Interestingly, targeting HDAC3 and HDAC6, but not other HDAC isoforms, by siRNA/pharmacological inhibitors mimicked the effects of SAHA in modulating the acetylation, expression, and nuclear translocation of survivin and induced autophagy in MCF7 and MDA-MB-231 cancer cells. Targeting HDAC3 also mimicked the effect of SAHA in up-regulating the expression and activity of proteasome, which might lead to the reduced protein stability of survivin in breast cancer cells. In conclusion, this study provides new insights into SAHA's molecular mechanism of actions in breast cancer cells. Our findings emphasize the complexity of the regulatory roles in different HDAC isoforms and potentially assist in predicting the mechanism of novel HDAC inhibitors in targeted or combinational therapies in the future.

ECONOMIC PROFITABILITY OF THE BAKKEN, NORTH DAKOTA UNCONVENTIONAL OIL PLAYS BASED ON A TYPICAL WELL PERFORMANCE WITH CURRENT MARKET CONDITIONS

Increases in oil prices after the economic recession have been surprising for domestic oil production in the United States since the beginning of 2009. Not only did the conventional oil extraction increase, but unconventional oil production and exploration also improved greatly with the favorable economic conditions. This favorable economy encourages companies to invest in new reservoirs and technological developments. Recently, enhanced drilling techniques including hydraulic fracturing and horizontal drilling have been supporting the domestic economy by way of unconventional shale and tight oil from various U.S. locations. One of the main contributors to this oil boom is the unconventional oil production from the North Dakota Bakken field. Horizontal drilling has increased oil production in the Bakken field, but the economic issues of unconventional oil extraction are still debatable due to volatile oil prices, high decline rates of production, a limited production period, high production costs, and lack of transportation. The economic profitability and viability of the unconventional oil play in the North Dakota Bakken was tested with an economic analysis of average Bakken unconventional well features. Scenario analysis demonstrated that a typical North Dakota Bakken unconventional oil well is profitable and viable as shown by three financial metrics; net present value, internal rate of return, and break-even prices.

Autoinducer-2 plays a crucial role in gut colonization and probiotic functionality of Bifidobacterium breve UCC2003

In the present study we show that luxS of Bifidobacterium breve UCC2003 is involved in the production of the interspecies signaling molecule autoinducer-2 (AI-2), and that this gene is essential for gastrointestinal colonization of a murine host, while it is also involved in providing protection against Salmonella infection in Caenorhabditis elegans. We demonstrate that a B. breve luxS-insertion mutant is significantly more susceptible to iron chelators than the WT strain and that this sensitivity can be partially reverted in the presence of the AI-2 precursor DPD. Furthermore, we show that several genes of an iron starvation-induced gene cluster, which are downregulated in the luxS-insertion mutant and which encodes a presumed iron-uptake system, are transcriptionally upregulated under in vivo conditions. Mutation of two genes of this cluster in B. breve UCC2003 renders the derived mutant strains sensitive to iron chelators while deficient in their ability to confer gut pathogen protection to Salmonella-infected nematodes. Since a functional luxS gene is present in all tested members of the genus Bifidobacterium, we conclude that bifidobacteria operate a LuxS-mediated system for gut colonization and pathogen protection that is correlated with iron acquisition.

Nijinsky review: Passion meets frailty in triumphant performance

His story is one of the most famous of the 20th century. As a dancer, he was a beacon of modernism, an icon of androgynous sensuality, and a performer with spectacular athletic prowess. As a choreographer, his experiments with movement – often harsh, primitive and contextualised within a nostalgia for Russia's pagan past – ended with a deconstruction of ballet as an art form, severed from its links to classical technique in favour of a movement seen as revolutionary.