991 resultados para 4-Aryl-3


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The present paper shows that the sum of two binomial integrals, such as A ∫ x p (a + bx q)r dx + B ∫ x p (a + bx q)r dx, where A and B are real constants and p, q, r are rational numbers, can, in special cases, lead to elementary integrals, even if each by itself is not elementary. An example of the case considered is given by the integral ∫ x _____-___ 3 dx = 1/2 ∫ x-½ (x - 1)-⅓ dx - 6 √ x ³√(x - 1)4 = 1/3 ∫ x-½ (x - 1)-¾ dx On the rigth hand side of the last equality both integral are not elementary. But the use of integration by parts of one of them leads to the solution: ∫ x _____-___ 3 dx = x½ (x - 1)-⅓ + C. 6 √ x ³√(x - 1)4

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In order to know potassium availability in "leucita de Poços de Caldas" from Poços de Caldas, Minas Gerais, a Mitscherlich pot experiment was set up. The pots were filled with 6 kilograms of sieved (4 mm) "Terra Roxa Misturada" soil. Rice (Oryza sativa, L.), Dourado Agulha variety was the testing plant. Doses of potassium referred to are 1,5 g (as K(2)0) from both KCl and "leucita de Poços de Caldas". There were 6 treatments, with 3 repetitions, as follows: 1) Control; 2) NP + 1 dose K (KCl); 3) NP + 2 doses K (KCl)); 4) NP + 3 doses K (KCl); 5) NP + 1 dose K (leucita); 6) NP + 2 doses K (leucita) and 7) NP + 3 doses K (leucita). Each pot received 50 seeds. Five days after germination the seedlings were thinned to 35. Harvesting took place 4 months after germination. Potassium (as KCl) promoted an increase in yield of both stalk and grain as compared with control. Potassium content in the leaves was also higher in all treatment in which KCl was supplied. Potassium, as "leucita de Poços de Caldas» did not show any favorable effect on both stalk and grain yield and on its content in the leaves.

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v. 4 pt. 3 (1914)

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v.4:no.3(1925)

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Estudaram-se os efeitos da aplicação de sulfato de amônio e reguladores de crescimento no peso médio dos frutos de tomateiro (Lycopersicon esculentum Mill.) cultivares "Angela" e "Roma". Em dois ensaios efetuou-se a aplicação de (NH4)2 SO4 (2g/l solo), SADH 3000 ppm, SADH + (NH4)2 SO4, CCC 2000 ppm, CCC+ (NH4)2 SO4, GA 100 ppm, GA + (NH4)2 SO4, além do tratamento controle. Em outros dois ensaios, além do controle, realizou-se a aplicação de 1-(2,4-diclorofenoxiacetil) -3,5- dimetil pirasol 3,75, 15,00 e 7,50 ppm, e de CEPA nas concentrações de 500, 1000 e 1500 ppm. Verificou-se que o SADH promoveu redução no peso médio dos frutos dos tomateiros "Angela", em relação ao tratamento com (NH4)2 SO4. A incorporação de sulfato de amônio no solo restringiu os efeitos detrimentals da aplicação foliar de SADH. Pulverização com CCC, GA, Tomakon e CEPA não afetou o peso médio dos frutos das cultivares "Angela" e "Roma".

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Between January 2007 and December 2010, the abundance of medium-sized mammals was studied, with special focus on the Molina's hog-nosed skunk, Conepatus chinga (Molina, 1782), at four locations in southern Brazil. In this study, transect line methodology was used to obtain data for Distance Analyses. Transects were traveled by car at night, searching with spotlights along the edges of secondary roads in agricultural landscapes. Along 1,811 km, we obtained 620 observations of 20 mammal species. The most common species was the exotic European hare, Lepus europaeus (Pallas, 1778); the highest abundance estimated for South America was observed in one of the study areas, where its density was estimated as 32 individuals/km². Carnivores were the most commonly recorded mammals, represented by 10 species and comprising 51% of all observations. Molina's hog-nosed skunk occurred in all study areas, but occurred in sufficient numbers to obtain density estimates in only two of the areas. We estimated 1.4 to 3.8 individuals/km², in the first density estimate made by the transect method for a member of Conepatus in the Neotropics. These values are similar to those estimated for North American species of Mephitidae. In Brazil, C. chinga is apparently more abundant in the Pampa biome than in the grasslands of the Atlantic Forest. For two other carnivores, Lycalopex gymnocercus (Fisher, 1814) and Cerdocyon thous (Linnaeus, 1766), we estimated preliminary densities that were similar to those previously cited for different regions.

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This work describes the spatial-temporal variation of the relative abundance and size of Limnoperna fortunei (Dunker, 1857) collected in São Gonçalo Channel through bottom trawl with a 0.5 cm mesh, at depths between 3 and 6 m. The estimative of mean relative abundance (CPUE) ranged from 2,425.3 individuals per drag (ind./drag) in the spring to 21,715.0 ind./drag in the fall, with an average of 9,515.3 ind./drag throughout the year. The estimated mean density of L. fortunei for the deep region of São Gonçalo Channel ranged from 1.2 to 10.3 ind./m², and it was recorded a maximum density of 84.9 ind./m² in the fall of 2008. The method of sampling using bottom trawl enabled the capture of L. fortunei under the soft muddy bottom of the channel, in different sizes ranging from 0.4 to 3.2 cm. This shows that the structure of the L. fortunei adult population under the bottom of the São Gonçalo Channel is composed mostly of small individuals (<1.4 cm), which represent up to 74% of the population collected.

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1) Os Cyathodiniidae são ciliados caracterisados morfologicamente pela existência de uma escavação de abertura antero-ventral, o pseudo-peristoma. A ciliatura é constituída por cilios uniformes dispostos em linhas transversas ou obliquas que revestem a parte externa do corpo situado ao nível do pseudo-peristoma onde penetram para revestir a superfície interna deste. Os Cyathodiniidae apresentam duplicidade nuclear nítida, que se manifesta morfologica e funcionalmente. 2) Os Cyathodiniidade não possuem boca e sua nutrição se faz por ormose através a membrana celular. 3) Os Cyathodiniidae não possuem boca e sua nutrição se faz por ormose através a membrana celular. 3) Os Cyathodiniidae se multiplicam por divisão binária que é acompanhada da perda dos cílios e fromação endógena de duas novas ciliaturas. O plano de divisão é longitudinal ou obliquo, isto é, se faz de acordo com as idéias de Chatton e Lwoff perpendicularmente á direção das cinelias. 4) A reorganização se faz exclusivamente por endomixia que é acompanhada da perda dos cílios e formação endógena da nova ciliatura. 5) A endomixia se passa em indivíduos que, quer pela sua morfologia, quer pelas dimensões, não diferem das fórmas neutras. 6) No processo de endomixia o micronúcleo por meio de duas mitoses sucessivas forma 4 nucleos, 3 dos quais degeneram, enquanto o restante vae formar por divisão o novo micronúcleo e a placenta que se transforma posteriormente no novo macro-nucleo. 7) O processo é identico, nos dois gêneros em que se sub-divide a família, diferindo apenas no modo por que se dá a degeneração do macronúcleo e dos restos da divisão do micronúcleo. 8) Enquanto no genero Cyathodinium a degeneração se faz por picnose, no gênero Cyathodinioides, o macronucleo degenera por desagregação em granulos e os restos de divisão do micronucleo, pelo processo de degeneração macronucleiforme descrito por Ivanic, terminando tambem por desagregação em granulos. 9) A degeneração macronucleiforme deve ser interpretada como uma evolução abortada e não como prova de ser o macronúcleo uma organela em degeneração, como pensa Ivanic. 10) Os Cyathodiniidae se transmitem por meio de quistos. 11) Os cyathodiniidae devem ser considerados como ciliados dos quais apresentam os princípios caracteres. São ciliados modificados pela vida parasitaria e seu estudo é improprio para esclarecer a filogenia desse grupo. 12) Os Cyathodiniidae devem ser incluídos na ordem Holotrica, sub-ordem Astomatea.

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ser.4:v.3-5 (1925-1927)

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Drugs are a rare cause of pancreatitis. Whereas some drugs are well known to induce an attack of pancreatitis, some people may be more prone to develop pancreatitis because of personal susceptibility. We describe a recurrent case of acute pancreatitis after administration of several drugs in a patient with intestinal inflammatory bowel disease that needed to be treated with subsequent antiinflammatory agents. Genetic mutation in the CFTR gene was found in the patient that led us to postulate that CFTR was a trigger for drug-induced acute pancreatitis. In conclusion, genetic analysis should be advised in case of recurrent pancreatitis in patient with intestinal inflammatory bowel disease.

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Molecular monitoring of BCR/ABL transcripts by real time quantitative reverse transcription PCR (qRT-PCR) is an essential technique for clinical management of patients with BCR/ABL-positive CML and ALL. Though quantitative BCR/ABL assays are performed in hundreds of laboratories worldwide, results among these laboratories cannot be reliably compared due to heterogeneity in test methods, data analysis, reporting, and lack of quantitative standards. Recent efforts towards standardization have been limited in scope. Aliquots of RNA were sent to clinical test centers worldwide in order to evaluate methods and reporting for e1a2, b2a2, and b3a2 transcript levels using their own qRT-PCR assays. Total RNA was isolated from tissue culture cells that expressed each of the different BCR/ABL transcripts. Serial log dilutions were prepared, ranging from 100 to 10-5, in RNA isolated from HL60 cells. Laboratories performed 5 independent qRT-PCR reactions for each sample type at each dilution. In addition, 15 qRT-PCR reactions of the 10-3 b3a2 RNA dilution were run to assess reproducibility within and between laboratories. Participants were asked to run the samples following their standard protocols and to report cycle threshold (Ct), quantitative values for BCR/ABL and housekeeping genes, and ratios of BCR/ABL to housekeeping genes for each sample RNA. Thirty-seven (n=37) participants have submitted qRT-PCR results for analysis (36, 37, and 34 labs generated data for b2a2, b3a2, and e1a2, respectively). The limit of detection for this study was defined as the lowest dilution that a Ct value could be detected for all 5 replicates. For b2a2, 15, 16, 4, and 1 lab(s) showed a limit of detection at the 10-5, 10-4, 10-3, and 10-2 dilutions, respectively. For b3a2, 20, 13, and 4 labs showed a limit of detection at the 10-5, 10-4, and 10-3 dilutions, respectively. For e1a2, 10, 21, 2, and 1 lab(s) showed a limit of detection at the 10-5, 10-4, 10-3, and 10-2 dilutions, respectively. Log %BCR/ABL ratio values provided a method for comparing results between the different laboratories for each BCR/ABL dilution series. Linear regression analysis revealed concordance among the majority of participant data over the 10-1 to 10-4 dilutions. The overall slope values showed comparable results among the majority of b2a2 (mean=0.939; median=0.9627; range (0.399 - 1.1872)), b3a2 (mean=0.925; median=0.922; range (0.625 - 1.140)), and e1a2 (mean=0.897; median=0.909; range (0.5174 - 1.138)) laboratory results (Fig. 1-3)). Thirty-four (n=34) out of the 37 laboratories reported Ct values for all 15 replicates and only those with a complete data set were included in the inter-lab calculations. Eleven laboratories either did not report their copy number data or used other reporting units such as nanograms or cell numbers; therefore, only 26 laboratories were included in the overall analysis of copy numbers. The median copy number was 348.4, with a range from 15.6 to 547,000 copies (approximately a 4.5 log difference); the median intra-lab %CV was 19.2% with a range from 4.2% to 82.6%. While our international performance evaluation using serially diluted RNA samples has reinforced the fact that heterogeneity exists among clinical laboratories, it has also demonstrated that performance within a laboratory is overall very consistent. Accordingly, the availability of defined BCR/ABL RNAs may facilitate the validation of all phases of quantitative BCR/ABL analysis and may be extremely useful as a tool for monitoring assay performance. Ongoing analyses of these materials, along with the development of additional control materials, may solidify consensus around their application in routine laboratory testing and possible integration in worldwide efforts to standardize quantitative BCR/ABL testing.