The Experience of Development and Application Perspectives of Learning Integrated Expert Systems in the Educational Process

The main principles and experience of development of learning integrated expert systems based on the third generation instrumental complex AT-TECHNOLOGY are considered.

Functionalised particles using dry powder coating in pharmaceutical drug delivery:promises and challenges

Introduction: Production of functionalised particles using dry powder coating is a one-step, environmentally friendly process that paves the way for the development of particles with targeted properties and diverse functionalities. Areas covered: Applying the first principles in physical science for powders, fine guest particles can be homogeneously dispersed over the surface of larger host particles to develop functionalised particles. Multiple functionalities can be modified including: flowability, dispersibility, fluidisation, homogeneity, content uniformity and dissolution profile. The current publication seeks to understand the fundamental underpinning principles and science governing dry coating process, evaluate key technologies developed to produce functionalised particles along with outlining their advantages, limitations and applications and discusses in detail the resultant functionalities and their applications. Expert opinion: Dry particle coating is a promising solvent-free manufacturing technology to produce particles with targeted functionalities. Progress within this area requires the development of continuous processing devices that can overcome challenges encountered with current technologies such as heat generation and particle attrition. Growth within this field requires extensive research to further understand the impact of process design and material properties on resultant functionalities.

Windowed-Wigner Representations, Interferences and Operators

2010 Mathematics Subject Classification: 42B10, 47A07, 35S05.

Pharmacology and the safe prescribing of drugs

Understanding the pharmacological principles and safe use of drugs is just as important in surgical practice as in any other medical specialty. With an ageing population with often multiple comorbidities and medications, as well as an expanding list of new pharmacological treatments, it is important that surgeons understand the implications of therapeutic drugs on their daily practice. The increasing emphasis on high quality and safe patient care demands that doctors are aware of preventable adverse drug reactions (ADRs) and interactions, try to minimize the potential for medication errors, and consider the benefits and harms of medicines in their patients. This chapter examines these aspects from the view of surgical practice and expands on the implications of some of the most common medical conditions and drug classes in the perioperative period. The therapeutic care of surgical patients is obvious in many circumstances – for example, antibacterial prophylaxis, thromboprophylaxis, and postoperative analgesia. However, the careful examination of other drug therapies is often critical not only to the sustained treatment of the associated medical conditions but to the perioperative outcomes of patients undergoing surgery. The benefit–harm balance of many therapies may be fundamentally altered by the stress of an operation in one direction or the other; this is not a decision that should wait until the anaesthetist arrives for a preoperative assessment or one that should be left to junior medical or nursing staff on the ward.

A lean elvek alkalmazása az egészségügyi folyamatok fejlesztésében = Applying lean principles in healthcare process development

A fejlett társadalmak egészségügyi szolgáltató rendszerei napjainkban kettős kihívással néznek szembe: miközben a társadalom a szolgáltatási színvonal emelkedését, a hibák számának a csökkenését várja el, addig a költségvetési terhek miatt a költségcsökkentés is feltétlenül szükséges. Ez a kihívás nagyságában összevethető azzal, amellyel az USA autóipara nézett szembe az 1970-es évektől. A megoldást az autóipar esetében a konkurens „lean” menedzsment elvek és eszközök megértése és alkalmazása jelentette. A tanulmány arra keresi a választ, hogy vajon lehetséges-e ennek a megoldásnak az alkalmazása az egészségügy esetében is. A cikk az egészségügy problémájának bemutatása után tárgyalja a lean menedzsment kialakulását és hogy milyen módon került köztudatba. A tanulmány második felében a szakirodalomban fellelhető, a témával kapcsolatos tapasztalatokat foglalja össze, majd levonja a következtetéseket. = In developed societies healthcare service systems are facing double challenge; society expects service level to rise and the number of mistakes to drop, but at the same time, because of the overloaded budgets, cutting cost is also absolutely necessary. This challenge compares to the one the US automotive industry was facing in the 1970-s. In case of the automotive industry the solution was the comprehension and application of the principles and the tools of lean management. This study aims to answer the question whether it is possible to apply this solution also in the case of the healthcare system. The article first introduces the problems in the healthcare system, than describes the formation of lean management concept and its wide spread. The second half of the study summarizes the available knowledge in the literature and drives conclusions.

International ethics and globalization

In the inherently anarchic international system the validity of moral principles is weakening. To overcome anarchy global governance is needed. It means efficient international institutions, but also pressures from the global civil society and the self-regulation of business. Multinational firms have the duty of cooperating in governance systems. They also have the duty of reconciling in their activity the two, equally legitimate claims of universalism and cultural relativism; i.e., applying universal moral principles and respecting local moral norms. Finally, multinationals must be guided by the principle of enhanced responsibility. However, although globalizing efforts are important in overcoming international anarchy and coordinating the protection of global commons, strong arguments support the notion that economic globalization does not promote sustainable development. Some form of localization of the economy is certainly needed. The challenge is to find a way towards more global governance with less economic globalization.

Válság és hitelderivatívák. A szintetikus fedezett adósságkötelezettségek (CDO-k) árazása és kockázataik (Crisis and loan derivatives. The pricing and risks of synthetic collateralized debt obligations)

A dolgozat első részében röviden áttekintjük a 2007-ben kezdődött pénzügyi válság lefolyását és a válsághoz vezető okokat. A bemutatás során igyekszünk végig a mögöttes folyamatokra és azok mozgatórugóira koncentrálni, ezzel megragadva a válság egyfajta "elméletét". A bemutatásból láthatóvá válik a hitelderivatívák kiemelt szerepe a válság során. A dolgozat második részében az egyik legnépszerűbb hitelderivatív termék, a szintetikus fedezett adósságkötelezettségek (CDO-k) matematikai modellezését és annak problémáit mutatjuk be. Sokak szerint ezek a matematikai modellek okozták - vagy legalábbis felerősítették - a válságot. Az elemzés során megmutatjuk, hogy nemcsak a modellezési eszközök nem voltak megfelelők, hanem az árazás elve sem állta meg a helyét a kockázatsemleges árazási keretben. Ez az eredmény élesen rámutat a mögöttes elméletek válságára. / === / The first part of the paper examines briefly the financial crisis of 2007 and its causes, focusing on its driving processes and key motifs. This shows clearly the importance and centrality of credit derivatives in the crisis. The second part presents a mathematical modelling of one of the most popular credit derivative products: synthetic collateralized debt obligations, along with the drawbacks and problems of the modelling process. It is widely claimed that these products caused or at least precipitated the crises. The authors show not only that the modelling tools were inappropriate, but that the principle for pricing did not match adequately the risk-neutral valuation framework.

Üzleti kapcsolatok – vállalati szemléletmód és gyakorlat = Business relationships - approach and practice in Hungary

A tanulmányunk fókuszában a vállalatközi kapcsolatok állnak. Az üzleti kapcsolatok, s ezek eredményes és hatékony menedzselése fontos értékteremtő tényező lehet. Az üzleti vállalkozások sikerét saját teljesítményük mellett üzleti partnereik (beszállítóik, alvállalkozóik, közvetítőik, megrendelőik, vevőik) teljesítménye, s a velük való kapcsolat eredményessége és hatékonysága egyaránt befolyásolja. Kutatásunkban a Versenyképesség-kutatás 2009. évi felmérésének eredményei alapján vizsgáltuk a vállalatközi kapcsolatok jellemzőit, lehetőség szerint összevetve a tapasztalatokat a korábbi hasonló felmérések (leginkább a 2004. évi, esetenként az 1996. és 1999. évi) következtetéseivel, eredményeivel. A tanulmányban a hosszú távú vállalati kapcsolatok általános jellemzését követően a kapcsolatok értékelésében megnyilvánuló vállalati szemléletmódot elemezzük, kiemelve, hogy a vállalatvezetők véleménye szerint a stabilitás, a kiszámíthatóság szempontjai általában elsődlegesek a kapcsolatokban rejlő együttműködési, fejlesztési lehetőségekhez képest. Különböző jellemzők (pl. vállalatméret, tulajdonos, teljesítmény) alapján kialakított csoportok véleményét összevetve rámutatunk, hogy az üzleti kapcsolatok megítélésében, a partnerek felé megjelenő elvárásokban a vállalatvezetők szemléletmódjában milyen eltérések észlelhetők. A tanulmány utolsó fejezetében a vevő-szállító kapcsolatokat támogató teljesítménymérési és -menedzsment eszköztárat értékeltük: a kedvező tendenciák, javuló támogatás ellenére sem állítható, hogy megfelelő, hatékony támogatást nyújtanak a vállalati információs és kontrolling rendszerek e kapcsolatok menedzseléséhez. A kutatás eredményeinek elemzése alapján látható, hogy az üzleti kapcsolatokra irányuló növekvő figyelem még kiaknázatlan lehetőségekkel párosul: a szemléletmód és a gyakorlat további fejlődése szükséges, hogy az üzleti kapcsolatok értékteremtő tényezőként a versenyképesség megalapozását, fejlesztését szolgálhassák a vállalatok szélesebb köre számára. ___________ The paper analyses the business relationships characteristics of Hungarian companies, based on data of the Competitiveness research program. Our goal was to characterize the business relationships and the causes of long term contracts and to analyse the view of different executives concerning the value of customer and supplier relationships. The last chapter of the paper evaluate the supporting role of performance measurement and management practice in the development of business relationships.

Foglalkoztatás-bővítési kilátások és akadályok az üzleti szférában(Employment expansion prospects and obstacles in the business sphere)

Empirikus vizsgálatok szerint a vállalatok fejlesztési törekvéseit Magyarországon is elsősorban a piaci kilátások határozzák meg, a finanszírozási körülmények szerepe jóval gyengébb. A beruházások és innovációk végrehajtása elsősorban a műszaki végzettségűek iránti keresletet növelheti, a szakképzetlen dolgozók körében viszont gyakran leépítésekre vezet. A vállalatok igénye és az állást keresők kompetenciái azonban nemcsak a szakmastruktúrában térnek el. A korábban megvalósított fejlesztéseknek a válság idején munkahelymegtartó szerepe volt. A jövőbeni fejlesztések munkaerőigényének kielégítésében mind az üzleti szektor szereplőinek, mind a szakpolitikáknak fontos tennivalói vannak. _______ According to recent empirical research development efforts of companies in Hungary are primarily determined by the market outlook, the role of financing conditions is much weaker. Implementation of investments and innovation can increase in first row the demand for technical professionals and often causes dismissals in unskilled labour. The demand of companies and competences of job seekers diverge not only in the professional structure. Earlier fulfilled development had workplace keeping role during the recession. Both actors of business sector and policies have important tasks to do in satisfying labour demand of future developments.

Political corruption in the Caribbean Basin: A comparative analysis of Jamaica and Costa Rica

Political corruption in the Caribbean Basin retards state economic growth and development, undermines government legitimacy, and threatens state security. In spite of recent anti-corruption efforts of intergovernmental and nongovernmental organizations (IGO/NGOs), Caribbean political corruption problems appear to be worsening in the post-Cold War period. This dissertation discovers why IGO/NGO efforts to arrest corruption are failing by investigating the domestic and international causes of political corruption in the Caribbean. The dissertation's theoretical framework centers on an interdisciplinary model of the causes of political corruption built within the rule-oriented constructivist approach to social science. The model first employs a rational choice analysis that broadly explains the varying levels of political corruption found across the region. The constructivist theory of social rules is then used to develop the structural mechanisms that further explain the region's levels of political corruption. The dissertation advances its theory of the causes of political corruption through qualitative disciplined-configurative case studies of political corruption in Jamaica and Costa Rica. The dissertation finds that IGO/NGO sponsored anti-corruption programs are failing because they employ only technical measures (issuing anti-corruption laws and regulations, providing transparency in accounting procedures, improving freedom of the press, establishing electoral reforms, etc.). While these IGO/NGO technical measures are necessary, they are not sufficient to arrest the Caribbean's political corruption problems. This dissertation concludes that to be successful, IGO/NGO anti-corruption programs must also include social measures, e.g., building civil societies and modernizing political cultures, for there to be any hope of lowering political corruption levels and improving Caribbean social conditions. The dissertation also highlights the key role of Caribbean governing elite in constructing the political and economic structures that cause their states' political corruption problems. ^

Phenomenology, psychoanalysis, and subject identity: Locating Narcissus and Proteus in the text

This paper examines the ways in which subject identity obtains in either philosophical or psychoanalytical theory, which subject may be duplicated—and disclosed—in literary narratives via their principles and ideas. ^ The technique has a double approach. First, the thesis examines subject formation in (and by) language, through psychoanalysis as it draws upon abiding mythic resources, phenomenological methods and aims (e.g., the subject as consciousness intending its object), and the existentialist turn. It then brings these ideas and principles to bear upon an analysis of literary works as cultural expressions of these identities. ^ Beginning with scientific and philosophical referents (as opposed to the somewhat ‘inclusive’ analysis of, for example, the New Criticism or explication de texte), allows for alternative readings not previously available to either author or reader. ^ Access to extra-literary sources, theories, and ideas enables a ‘reading’ of the subject on a par with one existing in the Life-World. ^

Human resource development professionals' perceptions about the Academy of Human Resource Development Standards on Ethics and Integrity

Professional standards of ethics proclaim the core values of a profession, describe expected professional duties and responsibilities, and provide a framework for ethical practice and ethical decision-making. The purpose of this mixed, quantitative and qualitative, survey study was to examine HRD professionals' perceptions about the AHRD Standards on Ethics and Integrity, how HRD professionals used the Standards for research and decision-making, and the extent to which the Standards provided guidance for ethical decision-making. Through an on-line survey instrument, 182 members of AHRD were surveyed. The open-ended questions were analyzed using thematic analysis to expand on, inform, and support the quantitative findings. The close-ended questions were analyzed with frequency distributions, descriptive statistics, cross tabulations, and Spearman rank correlations. The results showed a significant relationship between (a) years of AHRD membership and level of familiarity with the Standards, (b) years of AHRD membership and use of the Standards for research, and (c) level of familiarity with the Standards and use of the Standards for research. There were no significant differences among scholars, scholar practitioners, practitioners, and students regarding their perceptions about the Standards. The results showed that the Standards were not well known or widely used. Nevertheless, the results indicated overall positive perceptions about the Standards. Seventy percent agreed that the Standards provided an appropriate set of ethical principles and reflected respondents' own standards of conduct. Seventy-eight percent believed that the Standards were important for defining HRD as a profession and 54% believed they were important for developing a sense of belonging to the HRD profession. Fifty-one percent believed the Standards should be enforceable and 61% agreed members should sign the membership application form showing willingness to adhere to the Standards. Seventy-seven percent based work-related ethical decisions on personal beliefs of right and wrong and 56% on established professional values and rules of right and wrong. The findings imply that if the professional standards of ethics are to influence the profession, they should be widely publicized and discussed among members, they should have some binding power, and their use should be encouraged.

Resource management and optimization in wireless mesh networks

A wireless mesh network is a mesh network implemented over a wireless network system such as wireless LANs. Wireless Mesh Networks(WMNs) are promising for numerous applications such as broadband home networking, enterprise networking, transportation systems, health and medical systems, security surveillance systems, etc. Therefore, it has received considerable attention from both industrial and academic researchers. This dissertation explores schemes for resource management and optimization in WMNs by means of network routing and network coding.^ In this dissertation, we propose three optimization schemes. (1) First, a triple-tier optimization scheme is proposed for load balancing objective. The first tier mechanism achieves long-term routing optimization, and the second tier mechanism, using the optimization results obtained from the first tier mechanism, performs the short-term adaptation to deal with the impact of dynamic channel conditions. A greedy sub-channel allocation algorithm is developed as the third tier optimization scheme to further reduce the congestion level in the network. We conduct thorough theoretical analysis to show the correctness of our design and give the properties of our scheme. (2) Then, a Relay-Aided Network Coding scheme called RANC is proposed to improve the performance gain of network coding by exploiting the physical layer multi-rate capability in WMNs. We conduct rigorous analysis to find the design principles and study the tradeoff in the performance gain of RANC. Based on the analytical results, we provide a practical solution by decomposing the original design problem into two sub-problems, flow partition problem and scheduling problem. (3) Lastly, a joint optimization scheme of the routing in the network layer and network coding-aware scheduling in the MAC layer is introduced. We formulate the network optimization problem and exploit the structure of the problem via dual decomposition. We find that the original problem is composed of two problems, routing problem in the network layer and scheduling problem in the MAC layer. These two sub-problems are coupled through the link capacities. We solve the routing problem by two different adaptive routing algorithms. We then provide a distributed coding-aware scheduling algorithm. According to corresponding experiment results, the proposed schemes can significantly improve network performance.^

A colocação de pronomes clíticos em sentenças infinitivas preposicionadas na escrita brasileira dos séculos XIX e XX

In this work we present the description and analysis of the clitics collocation patterns in prepositional infinitive sentences within the Brazilian writing in the centuries XIX and XX. The corpus in analysis is comprised of letters of newspaper readers and newspaper writers, as well as of advertisements (ads) taken from Brazilian newspapers from different regions / states – Rio de Janeiro, Bahia, Ceará and Pernambuco – and written in the Centuries XIX and XX. They belong to the common minimum corpus of the project named Projeto para a História do Português Brasileiro (PHPB or Project to the History of the Brazilian Portuguese, in English). Its analysis is based on theoreticalmethodological postulates of the Theory of Variation and Change (WEINREICH; LABOV; HERZOG, 1968[2006]; LABOV, 1972[2008]); on the Theory of Principles and Parameters (CHOMSKY, 1981, 1986) and on the model of Grammar Competition (KROCH, 1989; 2001). By trying to articulate those presuppositions from both the theories we present a proposition of theoretical interface between the Variation Theory and the Grammar one. Concerning the empirical results achieved by means of this research, we could figure that, in the context in which there were prepositional infinitive sentences, the most significant independent variable to the occurrence of the proclisis is the type of preposition that comes before the verb in the infinitive. Before that, we found out that there are prepositions which strongly direct the proclisis, as it is the case of the prepositions in Portuguese sem, por, de and para, with all of them presenting Relative Weights over 0,52. Another important result is the one attested in the data referring the state of Rio de Janeiro (RJ). This state is the only one of the sample which is located in the Southeastern region and also presents itself as the main proclisis conditioner amongst the localities pertaining to the sample. In order to explain those results, we raised the hypothesis that the proclisis implementation may be more advanced in the Southeastern than in the Northeastern Brazil, however that hypothesis must be confirmed or refuted in future works. We also present, in this work, a theoretical explanation about the clitics colocation in prepositional infinitive sentences within the Brazilian writing in the XIX and XX centuries. The theoretical explanation we found to interpret the achieved results associates Magro’s proposition (2005), regarding the existence of prepositions occupying the nucleus PP and the existence of prepositions which can play the role of a completer and occupy the nucleus CP, according to Galves (2000; 2001), regarding the existent relation between the clitic colocation and the association of traits-phi to the functional categories COMP, Tense and Person. Our proposition is that the occurrence of prepositions which occupy the nucleus CP causes changes in the values attributed to the traits-phi and to the strong Vtraits in the functional categories COMP, Tense and Person. Thus, we defend that proclisis in Brazilian Portuguese (BP) is derived from the movement of the verb to the functional category tense in which there is the association of traits +V and traits +AGR, what legitimates the proclisis according to Galves´s proposition (2000; 2001).

Interplay between double-exchange, superexchange, and Lifshitz localization in doped manganites

Considering the disorder caused in manganites by the substitution Mn→Fe or Ga, we accomplish a systematic study of doped manganites begun in previous papers. To this end, a disordered model is formulated and solved using the variational mean-field technique. The subtle interplay between double exchange, superexchange, and disorder causes similar effects on the dependence of T_(C) on the percentage of Mn substitution in the cases considered. Yet, in La_(2/3)Ca_(1/3)Mn_(1-y)Ga_(y)O_(3) our results suggest a quantum critical point (QCP) for y ≈ 0.1–0.2, associated to the localization of the electronic states of the conduction band. In the case of La_(x)Ca_(x)Mn_(1-y)Fe_(y)O_(3) (with x = 1/3,3/8) no such QCP is expected.