Definição de indicadores para estimar custos de projeto e análise paramétrica dos eurocódigos estruturais

Dissertação de mestrado integrado em Engenharia Civil

Previsão de cheias em Barcelos

Dissertação de mestrado integrado em Engenharia Civil

Implementação de metodologias BIM na Direção de Engenharia de Barragens da EDP: casos de estudo de projeto de estruturas em obras hidroelétricas

Dissertação de mestrado integrado em Engenharia Civil

The effect of high-fat diet on rat’s mood, feeding behavior and response to stress

An association between obesity and depression has been indicated in studies addressing common physical (metabolic) and psychological (anxiety, low self-esteem) outcomes. Of consideration in both obesity and depression are chronic mild stressors to which individuals are exposed to on a daily basis. However, the response to stress is remarkably variable depending on numerous factors, such as the physical health and the mental state at the time of exposure. Here a chronic mild stress (CMS) protocol was used to assess the effect of high-fat diet (HFD)-induced obesity on response to stress in a rat model. In addition to the development of metabolic complications, such as glucose intolerance, diet-induced obesity caused behavioral alterations. Specifically, animals fed on HFD displayed depressive- and anxious-like behaviors that were only present in the normal diet (ND) group upon exposure to CMS. Of notice, these mood impairments were not further aggravated when the HFD animals were exposed to CMS, which suggest a ceiling effect. Moreover, although there was a sudden drop of food consumption in the first 3 weeks of the CMS protocol in both ND and HFD groups, only the CMS-HFD displayed an overall noticeable decrease in total food intake during the 6 weeks of the CMS protocol. Altogether, the study suggests that HFD impacts on the response to CMS, which should be considered when addressing the consequences of obesity in behavior.

Estudo numérico do escoamento e transporte de sedimentos em torno de pilares de pontes

Dissertação de mestrado integrado em Engenharia Civil

A integração do Building Information Modeling (BIM) num projeto de reabilitação

Dissertação de mestrado integrado em Engenharia Civil

Aplicação de metodologias BIM no contexto da construção da nova ponte sobre o Rio Dão

Dissertação de mestrado integrado em Engenharia Civil

The positive effect on ketamine as a priming adjuvant in antidepressant treatment.

Ketamine is an anesthetic with antidepressant properties. The rapid and lasting effect of ketamine observed in preclinical and clinical research makes it a promising therapeutic to improve current major depression (MD) treatment. Our work intended to evaluate whether the combined use of classic antidepressants (imipramine or fluoxetine) and ketamine would improve the antidepressant response. Using an animal model of depressive-like behavior, we show that the addition of ketamine to antidepressants anticipates the behavioral response and accelerates the neuroplastic events when compared with the use of antidepressants alone. In conclusion, our results suggest the need for a reappraisal of the current pharmacological treatment of MD.

Implementação de um sistema de previsão e controlo para operação otimizada de um sistema de recolha e armazenamento de água pluvial

Dissertação de mestrado integrado em Engenharia Civil

The Pope’s encyclical as a call for democratic social change

(Excerto) By addressing the ideologies and practices of the social dynamics entwined with climate change, the encyclical exposes the profoundly political character of global environmental change and its connection with economics and culture. The publication of the encyclical is action in the public space via language oriented to persuasion which, in Hannah Arendt’s terms, is the very essence of politics.

Analysis of the effects of the continuous electrode paste band on precordial leads of the electrocardiogram

OBJECTIVE - To determine if the application of a continuous electrode paste band on precordial leads results in alteration of the electrocardiographic tracing as compared with an adequate amount of electrode paste, and if the former condition does not cause uniform morphologies from V1 to V6. METHODS - The amplitude and morphology of the electrocardiographic waves on the precordial leads in electrocardiographic tracings, which were performed with standard (control group) or excessive (continuous band) application of the electrode paste, were compared. RESULTS - None of the 106 patients studied showed uniformity of the QRS morphology from V1 to V6. The eletrocardiographic alterations identified in the tracings performed with a continuous electrode paste band that showed statistical significance in relation to the control group were the following: inversion of the P wave in V1; inversion of the T wave in V1, V2, and V3; appearance of R' waves in V1 and V2; disappearance of S waves in V1; appearance of S waves in V5 and V6; alterations in the amplitude of almost all waves, in all leads. CONCLUSION - Application of a continuous electrode paste band in the precordial leads may cause significant alterations in the electrocardiographic tracing obtained.

Development of a poly(L-Lactic acid) based drug release system

Dissertação de mestrado em Biofísica e Bionanossistemas

Sistemas de controlo de gestão, empreendedorismo corporativo, estratégia e performance : contraste entre empresas familiares e não familiares

Mestrado em Contabilidade, Fiscalidade e Finanças Empresariais

Brazo Humano Robotizado

El proyecto es el desarrollo de un manipulador de 8 grados de libertad, su optimización para lograr mayor similitud al brazo humano y poder estudiar su comportamiento y factibilidad de imitar el comportamiento del brazo humano. Con el diseño optimizado en CATIA y la construcción del prototipo se iniciará el modelado de las ecuaciones de movimiento y su simulación en la computadora, se iniciará con la simulación del modelo 3D en tiempo real que contará con un ambiente virtual desarrollado en CATIA de donde será obtenida la información de los movimientos a realizar por el brazo para ser aplicadas luego en un ambiente real similar. Finalmente se procederá al ensamblado de todos los componentes mecánicos y electrónicos para el inicio de las pruebas de laboratorio y sus ensayos de funcionamiento y testeos de acuerdo a los requerimientos previstos. El brazo humano estará diseñado con una mano de dos dedos que pueda tomar objetos.