914 resultados para Empirical Mode Decomposition, vibration-based analysis, damage detection, signal decomposition
La délinquance des étrangers : criminalité, récidive et les facteurs influençant le retour en prison
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Résumé : La délinquance des étrangers se situe depuis quelques années au milieu de beaucoup de débats politiques. En même temps, la récidive constitue l'un des sujets d'étude classiques de la criminologie. Cette recherche combine ces deux phénomènes en s'intéressant aux causes de la délinquance et de l'éventuelle récidive d'un échantillon d'étrangers incarcérés en Suisse. Le cadre théorique repose sur une revue approfondie de la littérature scientifique sur la délinquance des étrangers ainsi que sur les facteurs influençant la récidive. Ces revues ont conduit à l'élaboration d'une série d'hypothèses qui ont été testées dans la partie empirique du travail. Cette dernière comprend l'étude des 500 dossiers des étrangers libérés des Etablissements pénitentiaires de la Plaine de l'Orbe (EPO, canton de Vaud, Suisse) entre 1995 et 1999, ainsi que le suivi de ces personnes, avec l'aide des données fournies par l'Office fédéral de la statistique, afin d'établir si elles avaient récidivé durant les cinq années postérieures à leur libération. Elle comprend également l'analyse de 125 entretiens conduits auprès des détenus des EPO entre 2005 et 2006 dont le but était d'établir, entre autres, leur perception subjective sur les causes de la délinquance et de la récidive. Les résultats indiquent un taux de récidive d'environ 30%. En outre, ils corroborent l'influence sur la récidive des facteurs identifiés par les recherches précédentes bien que, vu les particularités de l'échantillon étudié, certains de ces facteurs -tel que l'âge à la première condamnation ou l'âge à la sortie de prison-, présentent des divergences. En outre, l'analyse des entretiens a permis l'élaboration d'une nouvelle classification des causes de la récidive. Finalement, la recherche permet une connaissance plus approfondie des causes de l'implication dans la délinquance de la population de référence. The delinquency of the foreigners: criminality, recidivism and the factors that influence to the return to prison Abstract : The foreigners' delinquency is today in the middle of political debates. Moreover, recidivism is one of the classical subjects studied in criminology. The present research combines these two phenomena by studying the causes of foreigners' delinquency and recidivism. With the purpose of doing this research, a theoretical framework on the criminality of foreigners has been established through an extensive review of research literature on this subject as well as on the factors influencing recidivism. These reviews have allowed the establishment of a series of hypotheses that have been tested in the empirical part of the study. This empirical research includes the study of 500 cases of all foreigners released from the Penitentiary Establishment of the Plaine de l'Orbe (EPO, in the Vaud region) between 1995 and 1999. This population was then followed-up by means of data provided by the Swiss Federal Office of Statistics in order to know whether they had recidivated during the five years following their release. The empirical study also includes the analysis of interviews conducted with 125 inmates of EPO between 2005 and 2006 to determine what are, in the opinion of the inmates interviewed, the causes of recidivism and the causes of crime. The results show a recidivism rate of approximately 30%. Furthermore, the factors which, according to research analyzed, influence recidivism, have also been related to the recidivism of our sample. However, due to the fact that the sample studied consists of foreigners, some factors, such as age of the first conviction or age of release of prison, show some differences with respect to the literature. Finally, the information obtained from the interviews has allowed the establishment of a new classification on the causes of recidivism, and to get a deeper knowledge of the causes of crime involvement of the population studied.
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This article presents a global vision of images in forensic science. The proliferation of perspectives on the use of images throughout criminal investigations and the increasing demand for research on this topic seem to demand a forensic science-based analysis. In this study, the definitions of and concepts related to material traces are revisited and applied to images, and a structured approach is used to persuade the scientific community to extend and improve the use of images as traces in criminal investigations. Current research efforts focus on technical issues and evidence assessment. This article provides a sound foundation for rationalising and explaining the processes involved in the production of clues from trace images. For example, the mechanisms through which these visual traces become clues of presence or action are described. An extensive literature review of forensic image analysis emphasises the existing guidelines and knowledge available for answering investigative questions (who, what, where, when and how). However, complementary developments are still necessary to demystify many aspects of image analysis in forensic science, including how to review and select images or use them to reconstruct an event or assist intelligence efforts. The hypothetico-deductive reasoning pathway used to discover unknown elements of an event or crime can also help scientists understand the underlying processes involved in their decision making. An analysis of a single image in an investigative or probative context is used to demonstrate the highly informative potential of images as traces and/or clues. Research efforts should be directed toward formalising the extraction and combination of clues from images. An appropriate methodology is key to expanding the use of images in forensic science.
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Morphological transitions are analyzed for a radial multiparticle diffusion-limited aggregation process grown under a convective drift. The introduction of a tangential flow changes the morphology of the diffusion-limited structure, into multiarm structures, inclined opposite to the flow, whose limit consists of single arms, when decreasing density. The case of shear flow is also considered. The anisotropy of the patterns is characterized in terms of a tangential correlation function based analysis. Comparison between the simulation results and preliminary experimental results has been done.
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Hyperhomocysteinemia represents an independent risk factor for atherothrombotic disease. Physiopathological mechanisms of accelerated progression of atherosclerosis in presence of hyperhomocysteinemia are complex. Herein we report a clinical case which emphasis the importance of screening elevated homocystein in the absence of conventional risk factors in patients who suffer from premature atherosclerosis.
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Urotensin-II controls ion/water homeostasis in fish and vascular tone in rodents. We hypothesised that common genetic variants in urotensin-II pathway genes are associated with human blood pressure or renal function. We performed family-based analysis of association between blood pressure, glomerular filtration and genes of the urotensin-II pathway (urotensin-II, urotensin-II related peptide, urotensin-II receptor) saturated with 28 tagging single nucleotide polymorphisms in 2024 individuals from 520 families; followed by an independent replication in 420 families and 7545 unrelated subjects. The expression studies of the urotensin-II pathway were carried out in 97 human kidneys. Phylogenetic evolutionary analysis was conducted in 17 vertebrate species. One single nucleotide polymorphism (rs531485 in urotensin-II gene) was associated with adjusted estimated glomerular filtration rate in the discovery cohort (p = 0.0005). It showed no association with estimated glomerular filtration rate in the combined replication resource of 8724 subjects from 6 populations. Expression of urotensin-II and its receptor showed strong linear correlation (r = 0.86, p<0.0001). There was no difference in renal expression of urotensin-II system between hypertensive and normotensive subjects. Evolutionary analysis revealed accumulation of mutations in urotensin-II since the divergence of primates and weaker conservation of urotensin-II receptor in primates than in lower vertebrates. Our data suggest that urotensin-II system genes are unlikely to play a major role in genetic control of human blood pressure or renal function. The signatures of evolutionary forces acting on urotensin-II system indicate that it may have evolved towards loss of function since the divergence of primates.
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Introduction. Quantification of daily upper-limb activity is a key determinant in evaluation of shoulder surgery. For a number of shoulder diseases, problem in performing daily activities have been expressed in terms of upper-limb usage and non-usage. Many instruments measure upper-limb movement but do not focus on the differentiations between the use of left or right shoulder. Several methods have been used to measure it using only accelerometers, pressure sensors or video-based analysis. However, there is no standard or widely used objective measure for upper-limb movement. We report here on an objective method to measure the movement of upper-limb and we examined the use of 3D accelerometers and 3D gyroscopes for that purpose. Methods. We studied 8 subjects with unilateral pathological shoulder (8 rotator cuff disease: 53 years old ± 8) and compared them to 18 control subjects (10 right handed, 8 left handed: 32 years old ± 8, younger than the patient group to be almost sure they don_t have any unrecognized shoulder pathology). The Simple Shoulder Test (SST) and Disabilities of the Arm and Shoulder Score (DASH) questionnaires were completed by each subject. Two modules with 3 miniature capacitive gyroscopes and 3 miniature accelerometers were fixed by a patch on the dorsal side of the distal humerus, and one module with 3 gyroscopes and 3 accelerometers were fixed on the thorax. The subject wore the system during one day (8 hours), at home or wherever he/she went. We used a technique based on the 3D acceleration and the 3D angular velocities from the modules attached on the humerus. Results. As expected, we observed that for the stand and sit postures the right side is more used than the left side for a healthy right-handed person(idem on the left side for a healthy left-handed person). Subjects used their dominant upper-limb 18% more than the non-dominant upper-limb. The measurements on patients in daily life have shown that the patient has used more his non affected and non dominant side during daily activity if the dominant side = affected shoulder. If the dominant side affected shoulder, the difference can be showed only during walking period. Discussion-Conclusion. The technique developed and used allowed the quantification of the difference between dominant and non dominant side, affected and unaffected upper-limb activity. These results were encouraging for future evaluation of patients with shoulder injuries, before and after surgery. The feasibility and patient acceptability of the method using body fixed sensors for ambulatory evaluation of upper limbs kinematics was shown.
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Nest and territory defence are risky and potentially dangerous behaviours. If the resolution of life history trade-offs differs between individuals, the level of defence may also vary among individuals. Because melanin-based colour traits can be associated with life history strategies, differently coloured individuals may display different nest and territory defence strategies. We investigated this issue in the colour polymorphic tawny owl (Strix aluco) for which plumage varies from dark to light reddish melanic. Accordingly, we found that (1) our presence induced a greater response (flying around) from dark-coloured than light-coloured females and (2) dark reddish males suffered lower nest predation rates than light-coloured males. In experimentally enlarged broods, the probability that females reacted after we played back the hoot calls of a stranger male was higher if these females were lighter reddish; the opposite pattern was found in experimentally reduced broods with dark parents being more reactive than light parents. Finally, darker females alarmed more frequently when paired with a light than with a dark male, suggesting that partners adjust their behaviour to each other. We also tested whether colouration is used as a signal by conspecifics to adjust the level of their defensive behaviour. Accordingly, breeding females responded more vigorously to a dark than a light reddish stuffed tawny owl placed beside their nest. We conclude that melanin-based colouration is a signal of alternative nest and territory defence behaviour that depends on ecological factors.
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A general criterion for the design of adaptive systemsin digital communications called the statistical reference criterionis proposed. The criterion is based on imposition of the probabilitydensity function of the signal of interest at the outputof the adaptive system, with its application to the scenario ofhighly powerful interferers being the main focus of this paper.The knowledge of the pdf of the wanted signal is used as adiscriminator between signals so that interferers with differingdistributions are rejected by the algorithm. Its performance isstudied over a range of scenarios. Equations for gradient-basedcoefficient updates are derived, and the relationship with otherexisting algorithms like the minimum variance and the Wienercriterion are examined.
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Tämän diplomityön aiheena on lähtölogistiikan strateginen tarkastelu tutkimuksen kohdeyrityksenä olevassa terästehtaassa. Tavoitteena oli lähtölogistiikan tulevaisuusskenaarioiden laatiminen. Diplomityössä tarkastellaan mm. logistiikan epävarmuustekijöitä ja haasteita, erilaisten kuljetusmuotojen käyttöä sekä kohdeyrityksen materiaalivirtojen suuntautumista tulevaisuudessa. Työssä luodaan katsaus logistisen asiakaspalvelun elementteihin ja tutkitaan, mitä elementtejä asiakkaat pitävät tärkeinä. Lisäksi tarkastellaan, miten asiakkaiden vaatimukset kehittyvät tulevaisuudessa. Tutkimus toteutettiin laadullisena tapaustutkimuksena. Empiirinen aineisto kerättiin haastattelujen, sähköpostikyselyn sekä havainnoinnin avulla. Diplomityössä laadittujen skenaarioiden aiheiksi valikoituivat kuljettaminen, Venäjä sekä tuotteet, volyymi ja markkina-alueet. Positiivisen skenaarion mukaan kasvavat materiaalivirrat suuntautuvat Suomen lisäksi Ruotsiin, Keski-Eurooppaan sekä Itä-Eurooppaan, joka on noussut uudeksi markkina-alueeksi. Negatiivisessa skenaariossa kilpailu on kiristynyt ja Ovako Imatran asiakkaat ovat muuttaneet joukolla Aasiaan, jonne teräksen vieminen Suomesta ei olekannattavaa. Tutkimus osoitti, että trendi tilauserien pienentymisestä ja toimitussyklin tihentymisestä pätee myös Ovako Imatran asiakkaiden kohdalla. Erityisen tärkeiksi logistisen asiakaspalvelun elementeiksi nousivat toimitusvarmuus sekä joustavuus toimituksissa. Tutkimuksessa havaittiin, että asiakkaat haluaisivat saada informaatiota tuotteen toimitustilasta online-järjestelmän kautta.
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VVALOSADE is a research project of professor Anita Lukka's VALORE research team in the Lappeenranta University of Technology. The VALOSADE includes the ELO technology program of Tekes. SMILE is one of four subprojects of the VALOSADE. The SMILE study focuses on the case of the company network that is composed of small and micro-sized mechanical maintenance service providers and forest industry as large-scale customers. The basic principle of the SMILE study is the communication and ebusiness in supply and demand networks. The aim of the study is to develop ebusiness strategy, ebusiness model and e-processes among the SME local service providers, and onthe other hand, between the local service provider network and the forest industry customers in a maintenance and operations service business. A literature review, interviews and benchmarking are used as research methods in this qualitative case study. The first SMILE report, 'Ebusiness between Global Company and Its Local SME Supplier Network', concentrated on creating background for the SMILE study by studying general trends of ebusiness in supply chains and networks of different industries. This second phase of the study concentrates on case network background, such as business relationships, information systems and business objectives; core processes in maintenance and operations service network; development needs in communication among the network participants; and ICT solutions to respond needs in changing environment. In the theory part of the report, different ebusiness models and frameworks are introduced. Those models and frameworks are compared to empirical case data. From that analysis of the empirical data, therecommendations for the development of the network information system are derived. In process industry such as the forest industry, it is crucial to achieve a high level of operational efficiency and reliability, which sets up great requirements for maintenance and operations. Therefore, partnerships or strategic alliances are needed between the network participants. In partnerships and alliances, deep communication is important, and therefore the information systems in the network also are critical. Communication, coordination and collaboration will increase in the case network in the future, because network resources must be optimised to improve competitive capability of the forest industry customers and theefficiency of their service providers. At present, ebusiness systems are not usual in this maintenance network. A network information system among the forest industry customers and their local service providers actually is the only genuinenetwork information system in this total network. However, the utilisation of that system has been quite insignificant. The current system does not add value enough either to the customers or to the local service providers. At present, thenetwork information system is the infomediary that share static information forthe network partners. The network information system should be the transaction intermediary, which integrates internal processes of the network companies; the network information system, which provides common standardised processes for thelocal service providers; and the infomediary, which share static and dynamic information on right time, on right partner, on right costs, on right format and on right quality. This study provides recommendations how to develop this system in the future to add value to the network companies. Ebusiness scenarios, vision, objectives, strategies, application architecture, ebusiness model, core processes and development strategy must be considered when the network information system will be developed in the next development step. The core processes in the case network are demand/capacity management, customer/supplier relationship management, service delivery management, knowledge management and cash flow management. Most benefits from ebusiness solutions come from the electrifying of operational level processes, such as service delivery management and cash flow management.
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The Pseudomonas aeruginosa toxin L-2-amino-4-methoxy-trans-3-butenoic acid (AMB) is a non-proteinogenic amino acid which is toxic for prokaryotes and eukaryotes. Production of AMB requires a five-gene cluster encoding a putative LysE-type transporter (AmbA), two non-ribosomal peptide synthetases (AmbB and AmbE), and two iron(II)/α-ketoglutarate-dependent oxygenases (AmbC and AmbD). Bioinformatics analysis predicts one thiolation (T) domain for AmbB and two T domains (T1 and T2) for AmbE, suggesting that AMB is generated by a processing step from a precursor tripeptide assembled on a thiotemplate. Using a combination of ATP-PPi exchange assays, aminoacylation assays, and mass spectrometry-based analysis of enzyme-bound substrates and pathway intermediates, the AmbB substrate was identified to be L-alanine (L-Ala), while the T1 and T2 domains of AmbE were loaded with L-glutamate (L-Glu) and L-Ala, respectively. Loading of L-Ala at T2 of AmbE occurred only in the presence of AmbB, indicative of a trans loading mechanism. In vitro assays performed with AmbB and AmbE revealed the dipeptide L-Glu-L-Ala at T1 and the tripeptide L-Ala-L-Glu-L-Ala attached at T2. When AmbC and AmbD were included in the assay, these peptides were no longer detected. Instead, an L-Ala-AMB-L-Ala tripeptide was found at T2. These data are in agreement with a biosynthetic model in which L-Glu is converted into AMB by the action of AmbC, AmbD, and tailoring domains of AmbE. The importance of the flanking L-Ala residues in the precursor tripeptide is discussed.
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Drug combinations can improve angiostatic cancer treatment efficacy and enable the reduction of side effects and drug resistance. Combining drugs is non-trivial due to the high number of possibilities. We applied a feedback system control (FSC) technique with a population-based stochastic search algorithm to navigate through the large parametric space of nine angiostatic drugs at four concentrations to identify optimal low-dose drug combinations. This implied an iterative approach of in vitro testing of endothelial cell viability and algorithm-based analysis. The optimal synergistic drug combination, containing erlotinib, BEZ-235 and RAPTA-C, was reached in a small number of iterations. Final drug combinations showed enhanced endothelial cell specificity and synergistically inhibited proliferation (p < 0.001), but not migration of endothelial cells, and forced enhanced numbers of endothelial cells to undergo apoptosis (p < 0.01). Successful translation of this drug combination was achieved in two preclinical in vivo tumor models. Tumor growth was inhibited synergistically and significantly (p < 0.05 and p < 0.01, respectively) using reduced drug doses as compared to optimal single-drug concentrations. At the applied conditions, single-drug monotherapies had no or negligible activity in these models. We suggest that FSC can be used for rapid identification of effective, reduced dose, multi-drug combinations for the treatment of cancer and other diseases.
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Tutkimuksen tavoitteena on selvittää, miten kirjallisuudessa kuvattua asiakkuuden hallintaa voitaisiin soveltaa keskuspankin maksuliikepalveluissa. Tarkasteltavana ovat yleiset toimintatavat, sekä asiakkuuden hallintaa tukevat järjestelmät. Tutkimuksen päätavoitteena on Help Desk toiminnan kehittäminen. Tutkimuksessa tarkastellaan asiakkuuden hallinnan eri osa-alueita ottaen huomioon sekä asiakkaan, että palvelun tarjoajan näkökulmat. Asiakkuuden hallinta ymmärretään strategiana, jolla kyetään kuvaamaan kuinka koko organisaatio toimii asiakkaiden kanssa. Asiakkuuden hallinnan ydin on asiakkaan arvontuotantoprosessin ymmärtäminen. Käytettyjä lähdeaineistoja ovat olleet alan kirjallisuus, artikkelit sekä Internet-lähteet. Empirian taustan ovat muodostaneet asiantuntijahaastattelut sekä keskuspankin julkaisut, sisäiset toimintaohjeet ja vakiintuneet käytännöt. Tutkimuksen keskeinen tulos on, että asiakkuudenhallinnan perusajatukset ovat monin tavoin sovellettavissa keskuspankin melko ainutkertaiseen, teknisesti ja viestinnällisesti vaativaan maksuliikepalveluympäristöön, vaikka asiakkaiden lukumäärä onkin pieni. Hyötyjä voidaan saavuttaa jo asiakkuudenhallinnan peruskomponenttien ml. strategianäkökulma tuntemuksella ja melko pieniltäkin näyttävillä toimintatapa-, työnkulku- ja asennemuutoksilla. Asiakkuuden hallintaa tukevan tietoteknologian jonkinasteinen käyttöönotto voi tuoda lisäarvoa, mutta sen kustannukset ja hyödyt on punnittava tämäntyyppisessä ympäristössä tarkoin.
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Tutkimuksen tavoitteena on kehittää pitkäaikaisten projektien kassavirtaennusteita Foster Wheeler Energia Oy:ssä. Jotta tähän tutkielman pääongelmaan saadaan vastaus, tulee analysoida, mitkä tekijät vaikuttavat kassavirtaennusteiden onnistumiseen ja millaisia kassavirtojen ennustamiseen liittyviä ongelmia Foster Wheeler Energia Oy:ssä on ilmennyt. Tutkielma sisältää sekä teoreettisen että empiirisen osan. Teoriaosassa perehdytään projektitoimintaa ja kassavirtojen ennustamista koskeviin aikaisempiin tutkimuksiin. Teoriaosan pohjalta muodostetaan viitekehys ja joukko oletuksia. Sekä viitekehystä että oletuksia käytetään apuna empiirisen osan analyysissa. Analyysimenetelmä on kvalitatiivinen. Tutkimuksessa käytettävä tutkimusote on toiminta-analyyttinen. Tutkimustulosten mukaan kassavirtojen ennustamista voitaisiin Foster Wheeler Energia Oy:ssä kehittää ensinnäkin muuttamalla henkilöstön asenteita ja toimintatapoja. Muutoksen tarkoituksena on parantaa sekä henkilöstön kustannustietoisuutta että koko projektin etenemisen ajan kestävää yhteistyötä. Toinen keino ennusteiden parantamiseen on ennustamisessa nykyisin käytettävän hinnoitteluohjelman kehittäminen. Toteumatietoja hyväksikäyttävän ohjelman avulla ennusteet voidaan tehdä nopeammin ja tarkemmin kuin aikaisemmin.
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In this paper, a new algorithm for blind inversion of Wiener systems is presented. The algorithm is based on minimization of mutual information of the output samples. This minimization is done through a Minimization-Projection (MP) approach, using a nonparametric “gradient” of mutual information.