Reliure de : Notitia utraque cum Orientis tum Occidentis ultra Arcadii Honoriique Caesarum tempora... Praecedit autem D. Andreae Alciati libellus De magistratib. civilibusque ac militaribus officiis... Cui succedit descriptio urbis Romae quae sub titulo Pub. Victoris circumfertur, et altera urbis Constantinopolitanae incerto auctore, nunquam antequam typis excusa... Subjungitur Notitiis vetustus liber de rebus bellicis ad Theodosium Aug. et filios ejus Arcadium atque Honorium, ut videtur, scriptus, incerto autore. Item... Disputatio Adriani Aug. et Epicteti philosophi

[Notitia dignitatum omnium tam civilium quam militarium (latin). 1552]

Reliure de : Andreae Vesalii,... Epistola [ad Joachimum Roelants], rationem modumque propinandi radicis Chynae decocti, quo nuper... Carolus V. imperator usus est, pertractans ; et praeter alia quaedam, epistolae cujusdam ad Jacobum Sylvium sententiam recensens, veritatis ac potissimum humanae fabricae studiosis perutilem ; quum qui hactenus in illa nimium Galeno creditum sit, facile commonstret. Accessit quoque locuples rerum et verborum in hac ipsa epistola memorabilium index... [A Francisco Vesalio, auctoris fratre, editum.]

Numérisation partielle de reliure

[Illustrations de Brevis ac dilucida Burgundiae superioris... item brevis ad modum totius Galliae descriptio per eudem] / [Non identifié] ; Gilbert Cousin, aut. du texte

Comprend : [Planche entre les p. 48-49. Deux planches. Représentation du côté ouest et du côté est d'une ville. Habitations burgondes.] [Cote : BNF C214317] ; [Planche dépliante entre les p. 48-49. Partie gauche de la planche représentant le côté est d'une ville. Habitations burgondes.] [Cote : BNF C94455]

[Illustrations de Orbis situ ac descriptione...] / [Non identifié] ; Le Père Franciscus Monachus, aut. du texte

Comprend : [ Folios A1v ° et A2r °. Vue des deux cartes en couleur de l'hémisphère Européen-Africain et de l'hémisphère Américain. XVIè siècle.] [ Cote : BNF RCB 8010. ]

Human alveolar macrophages infected by virulent bacteria expressing SipB are a major source of active interleukin-18.

Recent publications have demonstrated that the protease caspase-1 is responsible for the processing of pro-interleukin 18 (IL-18) into the active form. Studies on cell lines and murine macrophages have shown that the bacterial invasion factor SipB activates caspase-1, triggering cell death. Thus, we investigated the role of SipB in the activation and release of IL-18 in human alveolar macrophages (AM), which are the first line of defense against inhaled pathogens. Under steady-state conditions, AM are a more important source of IL-18 than are dendritic cells (DC) and monocytes. Cytokine production by AM and DC was compared after both types of cells had been infected with a virulent strain of Salmonella enterica serovar Typhimurium and an isogenic sipB mutant, which were used as an infection model. Infection with virulent Salmonella led to marked cell death with features of apoptosis while both intracellular activation and release of IL-18 were demonstrated. In contrast, the sipB mutant did not induce such cell death or the release of active IL-18. The specific caspase-1 inhibitor Ac-YVAD-CMK blocked the early IL-18 release in AM infected with the virulent strain. However, the type of Salmonella infection did not differentially regulate IL-18 gene expression. We concluded that the bacterial virulence factor SipB plays an essential posttranslational role in the intracellular activation of IL-18 and the release of the cytokine in human AM.

[Illustrations de Descriptio ac delineatio geographica detectionis freti supra terras Americanas in China atque, Japonem ducturi] / [Non identifié] ; Henry Hudson, aut. du texte

Comprend : [Fig. au verso de la Page de Titre : un trois-mâts, enseigne de l'imprimeur.] [Cote : G 3486/Microfilm R 122140] ; [pl. double après le Titre :] Planisphère. [Cote : G 3486/Microfilm R 122140] ; [Carte double et dépl. après le Prologue : carte nautique de l'Atlantique Nord. Blason armorié avec devise "Dieu est mon droit".] Tabula Nautica (...). [Cote : G 3486/Microfilm R 122140] ; [Fig. après folio C2 : un Samoyède sur son traineau. Idoles vôtives.] [Cote : G 3486/Microfilm R 122140] ; [Carte dépl. et double avant folio C3 : carte de l'Arctique.] [Cote : G 3486/Microfilm R 122140] ; [Fig. au verso du Second Titre : un trois-mâts, enseigne de l'imprimeur.] [Cote : G 3486/Microfilm R 122140] ; [Carte double en reg. folio A2 : carte du Pôle, Norvège, Groënland, Nouvelle-Zélande etc.] [Cote : G 3486/Microfilm R 122140] ; [pl. double après p.16 : morses du grand Nord. Région du Spitzsberghe.] [Cote : G 3486/Microfilm R 122140] ; [Fig. p.18 : baleine du cercle polaire. Région du Spitzsberghe.] [Cote : G 3486/Microfilm R 122140]

Philo of Alexandria's De opificio mundi (LIII-LXI): discovering the essential features of Greek and Western Misogyny in a Platonising Jewish Text

The aim of this article is to show the Western centuries-old misogynist tradition from its origins in Greece by analysing a text by the allegorical interpreter of the Bible Philo of Alexandria, his De opifico mundi, which on many occasions is read by him from a Platonic point of view. The accurate analysis of the chapters devoted to the creation of the woman by God proves to what extent it is not possible to understand this text if one does not take into account a Greek philosophical tradition which was already centuries-old.

Filó d'Alexandria i el seu De opificio mundi (LIII-LXI): tot copsant les claus de la misogínia grega i occidental en un text jueu platonitzant.

L'objectiu d'aquest article és mostrar la secular tradició misògina occidental des dels seus orígens a Grècia tot analitzant un text de l'intèrpret al·legoric de la Bíblia Filó d'Alexandria, el De opificio mundi, al qual aplica una lectura fortament platonitzant. L'anàlisi acurada dels capítols dedicats a la creació divina de la dona i les seves conseqüències mostra fins a quin punt no és possible entendre aquest text sense tenir en compte una tradició filosòfica grega ja aleshores secular.

Filón de Alejandría y su De opificio mundi (LIII-LXI): descubriendo las claves de la misoginia griega y occidental platónica en un texto judío platonizante

El objetivo de este artículo es mostrar la secular tradición misógina occidental desde sus orígenes en Grecia, analizando un texto del intérprete alegórico de la Biblia Filón de Alejandría, el De opifico mundi, al cual aplica una lectura claramente platonizante. El análisis minucioso de los capítulos dedicados a la creación divina de la mujer muestra hasta qué punto no es posible entender este texto sin tener en cuenta una tradición filosófica griega ya entonces secular.

Chaotic, memory, and cooling rate effects in spin glasses: Evaluation of the Edwards-Anderson model

We investigate chaotic, memory, and cooling rate effects in the three-dimensional Edwards-Anderson model by doing thermoremanent (TRM) and ac susceptibility numerical experiments and making a detailed comparison with laboratory experiments on spin glasses. In contrast to the experiments, the Edwards-Anderson model does not show any trace of reinitialization processes in temperature change experiments (TRM or ac). A detailed comparison with ac relaxation experiments in the presence of dc magnetic field or coupling distribution perturbations reveals that the absence of chaotic effects in the Edwards-Anderson model is a consequence of the presence of strong cooling rate effects. We discuss possible solutions to this discrepancy, in particular the smallness of the time scales reached in numerical experiments, but we also question the validity of the Edwards-Anderson model to reproduce the experimental results.