Comparative study of human exposure to mercury in riverside communities in the Amazon region

Four populations in the Amazon area were selected for a comparative study of mercury-exposed and non-exposed populations: São Luiz do Tapajós, Barreiras, Panacauera, and Pindobal Grande. The highest mercury levels in human hair samples were found in São Luiz do Tapajós and Barreiras, greatly exceeding the limits established by the World Health Organization. Panacauera showed an intermediate level below 9 µg/g. This was the first comparative and simultaneous evaluation of mercury exposure in the Amazon area. Also, thanks to this type of monitoring, we were able to eliminate the uncertainties about the reference dose. On the basis of these data, we can conclude that the mercury levels detected in exposed populations of the Tapajós River basin may be dangerous not only because they are above the World Health Organization limits, but also because the simultaneous mercury detection in non-exposed populations with similar characteristics provided a valid control and revealed lower mercury levels. Our results support the importance of continuous monitoring in both exposed and non-exposed populations.

The importance of sensing one's movement in the world for the sense of personal identity

Within philosophy and cognitive science, the focus in relation to the problem of personal identity has been almost exclusively on the brain. We submit that the resulting neglect of the body and of bodily movements in the world has been detrimental in understanding how organisms develop a sense of identity. We examine the importance of sensing one’s own movements for the development of a basic, nonconceptual sense of self. More specifically, we argue that the origin of the sense of self stems from the sensitivity to spontaneous movements. Based on this, the organism develops a sense of “I move” and, finally, a sense of “I can move”. Proprioception and kinesthesis are essential in this development. At the same time, we argue against the traditional dichotomy between so-called external and internal senses, agreeing with Gibson that perception of the self and of the environment invariably go together. We discuss a traditional distinction between two aspects of bodily self: the body sense and the body image. We suggest that they capture different aspects of the sense of self. We argue that especially the body sense is of great importance to our nonconceptual sense of self. Finally, we attempt to draw some consequences for research in cognitive science, specifically in the area of robotics, by examining a case of missing proprioception. We make a plea for robots to be equipped not just with external perceptual and motor abilities but also with a sense of proprioception. This, we submit, would constitute one further step towards understanding creatures acting in the world with a sense of themselves.

Two new species of Rykellus (Acari: Mesostigmata: Ologamasidae) from Brazil and a key to the world species of the genus

Rykellus anibali n. sp. and Rykellus mineiroi n. sp. are described from adult females and males collected from litter and soil in the state of Sao Paulo, Brazil. A key for the identification of females of the eight recognisable world species of Rykellus is provided.

The Phycodnaviridae: The Story of How Tiny Giants Rule the World

The family Phycodnaviridae encompasses a diverse and rapidly expanding collection of large icosahedral, dsDNA viruses that infect algae. These lytic and lysogenic viruses have genomes ranging from 160 to 560 kb. The family consists of six genera based initially on host range and supported by sequence comparisons. The family is monophyletic with branches for each genus, but the phycodnaviruses have evolutionary roots that connect them with several other families of large DNA viruses, referred to as the nucleocytoplasmic large DNA viruses (NCLDV).The phycodnaviruses have diverse genome structures, some with large regions of noncoding sequence and others with regions of ssDNA. The genomes of members in three genera in the Phycodnaviridae have been sequenced. The genome analyses have revealed more than 1000 unique genes, with only 14 homologous genes in common among the three genera of phycodnaviruses sequenced to date. Thus, their gene diversity far exceeds the number of so-called core genes. Not much is known about the replication of these viruses, but the consequences of these infections on phytoplankton have global affects, including influencing geochemical cycling and weather patterns.

All the World's a Stage: Reaching English Language Learners through Drama

The use of drama with language instruction has long been considered a legitimate practice. A recent survey of the literature shows that English Language Learners (ELLs) may have even more to benefit from the use of drama in the classroom. Studies showed an increase in language and problem-solving ability, as well as student self-efficacy that was transferrable across activities. Following an analysis of the literature is a proposed curriculum based on the findings of the researchers cited. This unit is centered on dramatic activities that make use of all four language domains and includes the examination of plays in writing, on the stage, and as a playwright. In the end, students will be asked to combine all of their skills to put on a completely student-created production. An analysis of the factors surrounding the implementation of such a unit follows the unit itself.

Role of common mental and physical disorders in partial disability around the world

Background Mental and physical disorders are associated with total disability, but their effects on days with partial disability (i.e. the ability to perform some, but not full-role, functioning in daily life) are not well understood. Aims To estimate individual (i.e. the consequences for an individual with a disorder) and societal effects (i.e. the avoidable partial disability in the society due to disorders) of mental and physical disorders on days with partial disability around the world. Method Respondents from 26 nationally representative samples (n=61 259, age 18+) were interviewed regarding mental and physical disorders, and day-to-day functioning. The Composite International Diagnostic Interview, version 3.0 (CIDI 3.0) was used to assess mental disorders; partial disability (expressed in full day equivalents) was assessed with the World Health Organization Disability Assessment Schedule in the CIDI 3.0. Results Respondents with disorders reported about 1.58 additional disability days per month compared with respondents without disorders. At the individual level, mental disorders (especially post-traumatic stress disorder, depression and bipolar disorder) yielded a higher number of days with disability than physical disorders. At the societal level, the population attributable risk proportion due to physical and mental disorders was 49% and 15% respectively. Conclusions Mental and physical disorders have a considerable impact on partial disability, at both the individual and at the societal level. Physical disorders yielded higher effects on partial disability than mental disorders.

Do established prognostic factors explain the different mortality rates in ICU septic patients around the world?

Background. The aim of this paper was to clarify if previously established prognostic factors explain the different mortality, rates observed in ICU septic patients around the world. Methods. This is a sub-study from the PROGRESS study, which was an international, prospective, observational registry of ICU patients with severe sepsis. For this study we included 10930 patients from 24 countries that enrolled more than 100 patients in the PROGRESS. The effect of potential prognostic factors on in-hospital mortality was examined using univariate and multivariate logistic regression. The complete set of data was available for 7022 patients, who were considered in the multivariate analysis. Countries were classified according to country, income, development status, and in-hospital mortality terciles. The relationship between countries' characteristics and hospital mortality mortality was evaluated using linear regression. Results. Mean in-hospital mortality was 49.2%. Severe sepsis in-hospital mortality varied widely in different countries, ranging from 30.6% in New Zealand to 80.4% in Algeria. Classification as developed or developing country was not associated with in-hospital mortality (P=0.16), nor were levels of gross national product per capita (P=0.15). Patients in the group of countries with higher in-hospital mortality, had a crude OR for in-hospital death of 2.8 (95% CI 2.5-3.1) in comparison to those in the lower risk group. After adjustments were made for all other independent variables, the OR changed to 2.9 (95% CI 2.5-3.3). Conclusion. Severe sepsis mortality varies widely, in different countries. All known markers of disease severity and prognosis do not fully, explain the international differences in mortality,. Country, income does not explain this disparity, either. Further studies should be developed to verify if other organizational or structural factors account for disparities in patient care and outcomes. (Minerva Anestesiol 2012;78:1215-25)

Nuclear rainbow in the O-16+(27)AL system: The role of couplings at energies far above the barrier

High precision elastic and inelastic angular distributions have been measured for the O-16 + Al-27 system at a beam energy of 100 MeV. The data analysis confirms a rainbow formation as already predicted by parameter-free Coupled Channel calculations. It also helps to reveal the crucial role of inelastic couplings in the rainbow formation for heavier systems even at energies far above the Coulomb barrier. This feature, well known in atomic/molecular scattering, is experimentally studied for the first time in Nuclear Physics. (C) 2012 Elsevier B.V. All rights reserved.

Three new species of Gamasiphis (Acari: Mesostigmata: Ologamasidae) from Brazil, with complementary information about Gamasiphis plenosetosus Karg and a key to the world species of the genus

Gamasiphis Berlese is one of the most diverse genera of Ologamasidae, with 68 described species, corresponding to about 15% of the species of the family. Until now, a single species of this genus was known from Brazil. Gamasiphis salvadori sp. nov., Gamasiphis flechtmanni sp. nov. and Gamasiphis edmilsoni sp. nov. are described based on the morphology of adult females and males collected from litter and soil in Piracicaba, Sao Paulo State, Brazil. The holotype of Gamasiphis plenosetosus Karg, 1994 was examined, given its close similarity with the latter species, and complementary morphological information about it is provided. A key for the separation of females of the 60 recognizable world species of Gamasiphis is provided.

Cancer-related deaths among different treatment options in chronic coronary artery disease: results of a 6-year follow-up of the MASS II study

Introduction The primary end points of randomized clinical trials evaluating the outcome of therapeutic strategies for coronary artery disease (CAD) have included nonfatal acute myocardial infarction, the need for further revascularization, and overall mortality. Noncardiac causes of death may distort the interpretation of the long-term effects of coronary revascularization. Materials and methods This post-hoc analysis of the second Medicine, Angioplasty, or Surgery Study evaluates the cause of mortality of patients with multivessel CAD undergoing medical treatment, percutaneous coronary intervention, or surgical myocardial revascularization [coronary artery bypass graft surgery (CABG)] after a 6-year follow-up. Mortality was classified as cardiac and noncardiac death, and the causes of noncardiac death were reported. Results Patients were randomized into CABG and non-CABG groups (percutaneous coronary intervention plus medical treatment). No statistical differences were observed in overall mortality (P = 0.824). A significant difference in the distribution of causes of mortality was observed among the CABG and non-CABG groups (P = 0.003). In the CABG group, of the 203 randomized patients, the overall number of deaths was 34. Sixteen patients (47.1%) died of cardiac causes and 18 patients (52.9%) died of noncardiac causes. Of these, seven deaths (20.6%) were due to neoplasia. In the non-CABG group, comprising 408 patients, the overall number of deaths was 69. Fifty-three patients (77%) died of cardiac causes and 16 patients (23%) died of noncardiac causes. Only five deaths (7.2%) were due to neoplasia. Conclusion Different treatment options for multivessel coronary artery disease have similar overall mortality: CABG patients had the lowest incidence of cardiac death, but the highest incidence of noncardiac causes of death, and specifically a higher tendency toward cancer-related deaths. Coron Artery Dis 23:79-84 (C) 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins.

Late clinical outcomes after implantation of drug-eluting stents coated with biodegradable polymers: 3-year follow-up of the PAINT randomised trial

Aims: The long-term clinical performance of drug-eluting stents (DES) coated with biodegradable polymers is poorly known. Methods and results: A total of 274 coronary patients were randomly allocated to paclitaxel-eluting stents, sirolimus-eluting stents, or bare metal stems (2:2:1 ratio). The two DES used the same biodegradable polymers and were identical except for the drug. At three years, the pooled DES population had similar rates of cardiac death or myocardial infarction (9.0% vs. 7.1; p=0.6), but lower risk of repeat interventions (10.0% vs. 29.9%; p<0.01) than controls with bare stents. The cumulative 3-year incidence of definite or probable stent thrombosis in the pooled DES group was 2.3% (first year: 1.8%; second year: 0.4%; third year: zero). There were no significant differences in outcomes between paclitaxel- and sirolimus-eluting stents. Conclusions: The biodegradable-polymer coated DES releasing either paclitaxel or sirolimus were effective in reducing the 3-year rate of re-interventions.

Blattisocius (Acari, Blattisociidae) species from Brazil, with description of a new species, redescription of Blattisocius keegani and a key for the separation of the world species of the genus

Fifteen species have been placed in Blattisocius Keegan of which only three were previously reported from Brazil. These mites are found in several different habitats and often mentioned as predators of pests of stored food. In this work, specimens of this genus collected from commercial dog food in Brazil were determined as a new species which is here described as Blattisocius everti n. sp. and the closely related Blattisocius keegani Fox, here redescribed. Subsequently, other specimens of Blattisocius deposited in the mite collection of "Departamento de Entomologia e Acarologia of Escola Superior de Agricultura "Luiz de Queiroz", Universidade de Sao Paulo" were examined and identified. Finally, a dichotomous key to separate the world species of Blattisocius was elaborated based on the examination of the specimens at hand and on the descriptions and redescriptions of other species.

A new species of Hydrogamasellus (Acari: Mesostigmata: Ologamasidae) from Brazil, with a key to the world species of the genus

Hydrogamasellus alagoensis n. sp. is described based on the morphology of adult females and males collected from litter in the State of Alagoas, Brazil. Six new combinations are proposed, namely Acugamasus avium (Karg, 1976) n. comb., Ologamasus lanceolatus (Karg, 1976) n. comb., Ologamasus microcrinis (Karg, 1979) n. comb., Ologamasus testudinis (Karg, 1976) n. comb., Rykellus longopilus (Karg, 1976) n. comb. and Rykellus ubatubaensis (Hirschmann, 1966) n. comb., and a key for the separation of females of the eighteen recognizable world Hydrogamasellus species is provided.