Preparação e caracterização de coacervatos e vidros a base de fosfato, dopados com európio

Pós-graduação em Química - IQ

As empresas familiares da cidade de Franca: um estudo sob a visão do Serviço Social

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Eletrificação e crescimento industrial no estado de São Paulo: 1880-1940

O objetivo deste trabalho é evidenciar a existência de relações entre progresso técnico e desenvolvimento econômico no processo de formação da economia brasileira. Em seu aspecto mais específico, refere-se ao estudo do desenvolvimento da eletrificação e seus efeitos sobre o crescimento industrial no Estado de São Paulo, no período compreendido entre as duas décadas finais do século passado até a década de 1930. Durante este período - quando a economia e a sociedade brasileiras se transformam pelo desenvolvimento de relações de produção de natureza capitalista, ocorridas a partir do fim do escravismo, da introdução do trabalho assalariado, da expansão cafeeira, do aparecimento da ferrovia e dos bancos, das primeiras indústrias e, enfim, de atividades voltadas ao desenvolvimento do mercado interno - , o desenvolvimento da eletrificação e, especialmente, o uso de força motriz elétrica na indústria constituíram transformações essenciais. A o provocarem alterações irrevogáveis na base técnica da indústria contribuíram, também, para a alteração do padrão de acumulação.

Inclusion complex of S(-) bupivacaine and 2-hydroxypropyl-β-cyclodextrin: study of morphology and cytotoxicity

Local anesthetics (LA) belong to a class of pharmacological compounds that attenuate or eliminate pain by binding to the sodium channel of excitable membranes, blocking the influx of sodium ions and the propagation of the nerve impulse. S (-) bupivacaine (S(-) bvc) is a local anesthetic of amino-amide type, widely used in surgery and obstetrics for sustained peripheral and central nerve blockade. This article focuses on the characterization of an inclusion complex of S(-) bvc in 2-hydroxypropyl-ß-cyclodextrin (HP-ß-CD). Differential scanning calorimetry, scanning electron microscopy and X-Ray diffraction analysis showed structural changes in the complex. In preliminary toxicity studies, the cell viability tests revealed that the inclusion complex decreased the toxic effect (p<0.001) produced by S(-) bvc. These results suggest that the S(-) bvc:HP-ß-CD inclusion complex represents a promising agent for the treatment of regional pain. Keywords: S(-) bupivacaine; cyclodextrin; inclusion complex.

Biodegradação de filmes de polietileno de baixa densidade (PEBD), polihidroxibutirato-co-hidroxivalerato (PHBV) e blenda de PEBD/PHBV (70/30), em coluna de solo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da interação de amino derivados de quitosana com o plasmídeo VR1412

Pós-graduação em Química - IBILCE

Caracterização microestrutural e mecânica de trilhos ferroviários soldados de topo por caldeamento

Pós-graduação em Engenharia Mecânica - FEIS

Effect of 808 nm low-level laser therapy in exercise-induced skeletal muscle fatigue in elderly women

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Classificação e mapeamento de áreas de risco de enchentes e inundações no bairro Jardim Inocoop - Rio Claro - SP

In the last few decades, Brazil has experienced an accelerated urbanization process in which many cities have grown in a disorderly way occupying environmentally fragile areas unsuitable for habitation. Anthropogenic actions such as high levels of impermeable soil, structural changes in watercourses, lack of riparian vegetation, illegal presence of trash and rubbish along the river banks added to irregular settlements in floodplains result in the rise of high risk areas. When accompanied by intense and prolonged rainfall phenomena, those areas have been the scenery of serious accidents such as floods. This study aims to classify the level of the risk of floods in the neighborhood of Jardim Inocoop, in the town of Rio Claro, São Paulo countryside, Brazil. One of the main technical support to tackle this issue is the identification and classification of the risks. In order to classify the risk level of flood in this case study, the methodology adopted was developed by the Ministry of Cities and Technology Research Institute, and take into account the arrangement of the hydrological scenario, vulnerability of households and dangerous process according to the distance of the houses from the axis of drainage. Therefore, the risk levels adopted to classify are listed below: very high (MA), high risk (A), moderate (M) and low risk (B). In conclusion, it is imperative to develop prevention plans in order to avoid or to minimize the damages caused by natural disasters. Therefore, the zoning of the risk sceneries remains as an important issue once it helps to identify the areas with high level risk of flood. Consequently, the occupation must be regulated where there is low or absent risk and it must be often forbidden where the high risk of flood is detected. Thus, the present study remains as an attempt to notify the risk of floods through its spatialization on a map, remainig...(Complete abstract click electronic access below)

Estudos estruturais e cristalização de complexos formados entre toxinas botrópicas e inibidores vegetais

This research presents a study of structural complexes formed between the bothropstoxin BthTX-I and PrTX-I and phospholipase A2 (PLA2s) inhibitor 12- methoxy-4-methyl-voachalotine (MMV) of Tabernamontana catharinensis and rosmarinic acid (Cv-RA) of Rosmarinus officinalis. For both were used cocrystallization experiments with the toxins and inhibitors. In the future, the experimental three-dimensional structures of these complexes will be obtained through the technique of crystallography. Simultaneously, construction occurred in silico of inhibitors Cv-RA and MMV and attempts of docking between these binders and protein structures. These theoretical data provide important information regarding the nature of interactions between inhibitors, toxins and structural changes induced by the protein molecule inhibitors. Therefore, the acquisition of this information has great value to identification, characterization and development (drug design) of compounds with great potential for biotechnology and drug use. Considering further and more relevant aplications, these compounds could be used to control symptoms in many cases of ophidic poisoning and also in combating of pathological processes (degenerative inflammatory diseases and auto-immune diseases, Alzheimer's disease, schizophrenia, among others) whose causes are related to molecules belonging to the same groups of proteins which are classified bothropstoxin that were studied in this project

Amido retrogradado como excipiente de comprimidos para liberação controlada de fármacos: obtenção e caracterização

Pós-graduação em Ciências Farmacêuticas - FCFAR

Bidens pilosa L: efeitos protetores na inflamação intestinal

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Study of photoinduced birefringence vs As content in thin GeAsS films

Thin films of GeAsS glass are prepared by e-beam evaporation technique. Photoinduced birefringence (PIB) is studied as function of the As content with concentrations ranging from 10% to 40%. Raman spectroscopy is used as additional tool to explain the corresponding changes undergone by the material system. The breakdown of homopolar bonds is suggested as a possible mechanism of photo induced structural changes leading to the creation of the PIB.

Síntese de 14-aril-14h-dibenzol[a,j]xantenos e 4-aril-3,4-di-hidrobenzo[f]cumarinas promovida pelo pentacloreto de nióbio, com potencial aplicação na preparação de corantes sensibilizadores para utilização em dispositivos de Grätzel

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O Mercado de terras urbanas e seu papel na produção e transformação do espaço intraurbano em cidades médias: os Casos de Ribeirão Preto/SP e São Carlos/SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)