828 resultados para Depressão


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Stress is an environmental factor that may predispose individuals to depression. Benzodiazepines have been prescribed as effective drugs in these situations. The purpose of this study was histological evaluate of the effect of chronic stress and benzodiazepine drugs on bone healing. Bone cavities were created in both tibias of 40 male rats were divided into two groups: Control and Treaty. In this, the stressor stimulus was applied 40 days pre-operative and all post-operative days until sacrifice in the morning for 2 hours, by immobilizing restraint. These animals also received diazepam benzodiazepine group, daily, at a concentration of 5mg/Kg/peso body within 15 days of preoperative. In groups of five animals were sacrificed at 7, 14, 30 and 60 days post-surgery. At 7 days postoperatively, while the control group exhibited tissue rich in fibroblasts, the treated group showed newly formed tissue with few fibroblasts and capillaries along with lymphocytes and macrophages. At 14 days postsurgery, the control group showed newly formed trabecular bone while the treated group progressed to thin trabecular bone with numerous osteoblasts on their borders. At 30 days post-operative bone healing is complete in both groups. At 60 days post-operative characteristics observed in the treated and control groups are similar to the previous period, but with more advanced osteogenesis.

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Um equino macho, raça Manga Larga, de 20 dias de idade, pesando 55 kg foi atendido no Hospital Veterinário “Luiz Quintiliano de Oliveira” com histórico de queda no dia anterior, apresentando impotência funcional e desvio do eixo ósseo do membro pélvico esquerdo (MPE). Ao exame radiográfico, constatou-se uma fratura classificada como Salter- Harris tipo II, na região distal da tíbia esquerda, com indicação para osteossíntese. Ao exame físico geral, observou-se frequência cardíaca (FC) de 82 batimentos.min-1, frequência respiratória (f) de 60 movimentos.min-1, mucosas róseas, tempo de preenchimento capilar de dois segundos, temperatura retal (ToC) de 38,5oC e hidratação adequada. Como medicação pré-anestésica, administrou-se xilazina (0,5 mg.kg-1) IV. A indução foi realizada por meio da administração de midazolam (0,1mg.kg-1) e cetamina (2mg.kg-1) IV. Seguiu-se a intubação orotraqueal com sonda n o 12 conectando-se a um circuito anestésico com reinalação parcial de gases, e a manutenção foi realizada com isofluorano em fluxo diluente de oxigênio a 100%, sob ventilação espontânea. Realizou-se a técnica de anestesia peridural com o paciente em decúbito lateral direito, introduzindo uma agulha 30x8 percutaneamente até atingir o espaço peridural entre as vértebras L6 e S1, onde se administrou lidocaína a 2% (2,2mg.kg-1) com vasoconstritor, perfazendo um volume de 6 mLs. Adicionalmente foi realizado o bloqueio perineural dos nervos tibial e fibular do membro acometido, com administração de 5 mLs de lidocaína a 2% com vasoconstritor em cada ponto. A administração de anestésicos locais pela via peridural na região L6 – S1 não é rotineiramente usada em equinos, uma vez que provoca ataxia ou perda do tônus muscular, aumentando os riscos relacionados à intervenção anestésica. No entanto, a recuperação do potro nesse relato de caso foi rápida e isenta de complicações, provalvelmente proporcionando anestesia multimodal e consequentemente menor depressão cardiovascular. A associação da anestesia peridural e bloqueio dos nervos tibial e fibular à anestesia geral, pode ser uma alternativa para intervenções cirúrgicas em membros pélvicos de potros, uma vez que demonstrou ser efetiva e de fácil execução.

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The horse’s blood pressure is susceptible to changes induced by volatile anesthetics. Because of that, the use of anesthesic techniques which keep stable the horse´s blood pressure is essencial. Ketamine is an important induction and maintenance anesthetic agent used in the horse anesthesia practice mainly to improve the blood pressure. S(+)-ketamine provides the same effects on the blood pressure, with greater analgesic results and less side effects than the normal ketamine. Although some studies have been conducted with ketamine continuous rate infusion during the halothane anesthetized horses, the S(+)-ketamine has not been evaluated yet. Considering the increased use of ketamine, it is important to evaluate its cardiovascular and respiratory effects in halothane anesthetized horses. To conclude, S(+)-ketamine 0.01mg/kg/min. continuous rate infusion did not induce additive cardiovascular and respiratory depression in halothane anesthetized horses.

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Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

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This study aimed to verify the relationship between depression, hopelessness and family support. to this aim, were applied the Escala Baptista de Depressão-Adulto EBADEP- A, The Beck Hopelessness Scale –BHS, Inventário de Percepção de Suporte Familiar- IPSF and a sociodemographic questionnaire on a sample of 198 undergraduate of Pharmacy and Psychology courses of a particular university at São Paulo state (Brazil) with mean age of 23.44 years (SD = 6.8), and with a prevalence of women (80.7%). Results showed significant and positive correlations between EBADEP- A and BHS and significant and negative correlations between EBADEP- A/ BHS and IPSF, indicating that the higher perception of family support the fewer depressive symptoms and hopelessness, agreeing with literature.

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Pós-graduação em Psicologia do Desenvolvimento e Aprendizagem - FC

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Evaluation and adequacy of land occupation in Permanent Preservation Areas (PPAs) are important to ensure quantity and quality of water and local biodiversity. The objective of the study was mapping PPAs according to the Brazilian Forest Code and quantifying land cover and use, establishing the conflict of PPAs occupation in the Ribeirão Lavapés sub watershed. The area is 11,154.58 ha, and is located in Botucatu city, Midwestern region of São Paulo state. For this reason, geoprocessing tools, such as Remote Sensing and the Geographic Information System (SIG) were used. The dominant classes of land use and cover were the Urban Zone in Reverse Cuesta, 4,394.27 ha (39.39%) and Annual Crops in the Peripheral Depression, 3,670.89 ha (39.39%). The mapped area of native forest vegetal cover in the sub watershed was of 1,109.70 ha. Regarding the mapping of PPAs, considering the total area of 1,721.80 ha, a total of 532.15 ha (30.91%) are covered by Riparian Forest and 1,189.65 ha (69.09%) had no native riparian vegetation, therefore, requiring its reforestation.

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Pós-graduação em Fisiopatologia em Clínica Médica - FMB

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Pós-graduação em Ciência e Tecnologia Animal - FEIS

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Pós-graduação em Bases Gerais da Cirurgia - FMB

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Pós-graduação em Fisiopatologia em Clínica Médica - FMB