The Brazilian investment in science and technology

An analysis of Brazilian federal expenditures in science and technology is presented is this study. The 1990-1999 data were compiled from records provided by two federal agencies (MCT and CNPq) responsible for managing most of the national budget related to these activities. The results indicate that the federal investments in Brazilian science and technology stagnated during the last decade (US$ 2.32 billion in 1990, US$ 2.39 billion in 1996, and US$ 2.36 billion in 1999). In contrast, a great increase in private investments in research was acknowledged both by industry and by the government during the same period, from US$ 2.12 to US$ 4.64 billion. However, this investment did not result in an increase in invention patents granted to residents (492 in 1990 and only 232 in 1997) or in a reduction of patent costs. Despite this unfavorable scenario, the number of graduate programs in the country has increased two-fold in the last decade and the contribution of Brazilians to the database of the Institute for Scientific Information has increased 4.7-fold from 1990 (2,725 scientific publications) to 2000 (12,686 scientific publications). Unstable federal resources for science, together with the poor returns of private resources in terms of developing new technologies, may jeopardize the future of Brazilian technological development.

[Kirjallisuutta]

Kirjallisuusarvostelu

A strategy for obtaining social benefits from the gene revolution

The strategy described in the present paper offers details about the possibility for Brazil to play a more substantial role in the gene revolution. If successfully applied, the powerful science-based technology currently available in Brazil can contribute to extend the benefits of the gene revolution to the poorest countries, very much like the Green Revolution did in the past, thereby reducing the hunger syndrome which claimed the lives of millions of people in some Asian countries, particularly Pakistan and India, decades ago. In his visit to Brazil in February 2004, Norman Borlaug had the opportunity to witness the success of Brazilian agriculture. At a Conference held at ESALQ - Superior School of Agriculture Luiz de Queiroz in Piracicaba, SP, Brazil, he stated that the 21st century revolution will come from Brazil in the area of agriculture. He also said that reducing hunger is essential for the world to achieve socioeconomic stability. A central question remains unanswered: who will fund this revolution? The FAO 2003-2004 Annual Report listed the barriers preventing the gene revolution from reaching the poorest countries: inadequate regulatory procedures - Intellectual Property Rights and Biosafety, poorly functioning seed delivering systems and weak domestic plant breeding capacity; all are discussed in this paper.

Ilmastonmuutosteknologiat maailman patenttijärjestelmissä: Case autoteollisuus

Tässä työssä tarkastellaan kahden kansainvälisen patenttiluokitusjärjestelmän vihreiden teknologioiden luokitusjärjestelmiä autoteollisuudessa. Työn tarkoitus on tutkia, kuinka paljon vihreän teknologian patenttianalyysin tulokset eroavat toisistaan, jos tutkimuksissa käytetään eri patenttien luokitusjärjestelmiä. Vanhempi järjestelmä, International Patent Classification, on asemansa vakiinnuttanut kansainvälinen patenttienluokitusjärjestelmä. Vasta viime vuosina käyttöön otettu Cooperative Patent Classification on Euroopan ja Yhdysvaltojen patenttijärjestöjen kehittämä patenttien luokitusjärjestelmä. Tutkimusmenetelmissä hyödynnetään patenttianalyysia ja joukko-oppia. Tutkimuksessa vihreiden teknologioiden luokittelumenetelmien vertailukohteille saatiin määrällisesti samankaltaiset tulokset, mutta niiden sisältämät patentit eivät olleet pääsäännöllisesti samoja. Työssä tarkastellaan myös Toyotan, Daimlerin ja Fordin vihreiden autoteknologiapolkujen kehitystä. Varsinkin Toyota ja Daimler tulevat yhä enemmän panostamaan sähkö- ja hybridiautoihin verrattuna polttomoottoriautoihin.

Human fetal malformations associated with the use of an angiotensin II receptor antagonist: Case Report

Introduction: The potential risks related to drug exposure during pregnancy represent a vast chapter in modern obstetrics and data regarding the safety of antihypertensive drugs during pregnancy are relatively scarce. Case report: A 37-year-old patient discovered her fifth pregnancy at our hospital after 26 weeks and 4 days of gestation. She reported a history of hypertension and was currently being treated with Losartan. Hospitalization was recommended for the patient and further evaluation of fetal vitality was performed. On the fourth day an ultrasound was performed, resulting in a severe oligohydramnios, fetal centralization and abnormal ductus venosus. After 36 hours, the newborn died. Pathologic evaluation: At autopsy, the skullcap had large fontanels and deficient ossification. The kidneys were slightly enlarged. A microscopic examination detected underdevelopment of the tubules and the presence of some dilated lumens. Immunohistochemical detection of epithelial membrane antigen was positive. Immunoreactivity of CD 15 was also assayed to characterize the proximal tubules, and lumen collapse was observed in some regions. Discussion: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor antagonists (ARAs) are among the most widely prescribed drugs for hypertension. They are often used by hypertensive women who are considering become pregnant. While their fetal toxicity in the second or third trimesters has been documented, their teratogenic effect during the first trimester has only recently been demonstrated. Conclusion: Constant awareness by physicians and patients should be encouraged, particularly in regard to the prescription of antihypertensive drugs in women of childbearing age who are or intend to become pregnant.

Pienten osuuskuntien taloudellinen suoriutuminen

Tämän kandidaatintutkielman tarkoituksena on tutkia suomalaisia pienosuuskuntia niiden taloudellisen suoriutumisen näkökulmasta. Taloudellista suoriutumista tutkitaan tunnuslukujen avulla osuuskuntien tilinpäätöksissä olevien lukujen perusteella. Lisäksi tutkitaan, onko taloudellisessa suoriutumisessa eroavaisuuksia alueen, toimialan tai osuuskunnan koon välillä. Tutkimuksen aineisto on peräisin suomalaisten osuuskuntien tilinpäätöksistä, jotka ovat saatavilla Patentti- ja rekisterihallituksen Virre-tietokannasta. Aineistoa analysoidaan SAS Enterprise Guide -ohjelman avulla käyttäen apuna jakauma-analyysiä, yhteenvetotilastoja, Kruskal-Wallisin testiä sekä Spearmanin korrelaatioanalyysiä. Jakauma-analyyseillä ja yhteenvetotilastoilla muodostetaan aineistosta kokonaiskuva ja analysoidaan suomalaisten pienosuuskuntien tunnuslukuja. Kruskal-Wallis testillä analysoidaan taloudellisen suoriutumisen eroa alueellisesti ja toimialakohtaisesti ja Spearmanin korrelaatiokertoimella mitataan korrelaatiota liikevaihdon ja tunnuslukujen välillä. Tulosten perusteella osuuskuntien taloudellinen suoriutuminen ei ole sidoksissa toimialaan eikä alueeseen. Koon ja quick ration välillä löytyi negatiivinen korrelaatio. Suomalaisten pienosuuskuntien maksuvalmius on hyvällä tasolla. Myös vakavaraisuus on kohtalainen. Kannattavuuden tunnusluvut jäivät osuuskunnilla hyvin alhaisiksi ja osin jopa negatiivisiksi. Koska osuuskuntien toiminnan tarkoitus ei ole maksimoida voittoa, voidaan kannattavuuden tunnuslukuja pitää hyvällä tasolla, kunhan ne ovat positiivisia.

Tilintarkastajan vastuu kurinpidollisesta näkökulmasta

Tutkimuksen tavoitteena oli selvittää millainen on tilintarkastajan kurinpidollinen vastuu lakisääteisessä tehtävässä. Lisäksi tutkimuksessa selvitettiin, miten tilintarkastajan vastuu voi realisoitua ja millaisia kurinpidollisia seuraamuksia tilintarkastajille määrätään Suomessa. Tutkimuksen aineistona on käytetty TILA: n valvonta-asioiden ratkaisuja vuosina 2007 - 2014. Patentti – ja rekisterihallitus on vastannut kurinpidollisista asioista vuoden 2016 alusta lähtien. Tutkimuksessa noudatetaan käsitteellistä lähestymistapaa: tilintarkastajan vastuun ohella työssä on käsitelty muun muassa lakisääteistä tilintarkastusta, hyvää tilintarkastustapaa ja ammattieettisiä periaatteita. Työ on toteutettu laadullisena tutkimuksena ja aineisto koostuu dokumenteista koskien kurinpidollisia ratkaisuja vuosina 2007 - 2014. Tutkintatapausten käsittelyssä huomiota kiinnitettiin tutkinnan aloittamisen syihin ja tutkinnan seurauksena määrättyihin sanktioihin. Tutkintaan johtaneiden syiden väliltä pyrittiin löytämään yhteisiä tekijöitä. Lisäksi huomiota kiinnitettiin tutkintatapausten ja sanktioiden määrien kehitykseen. Tarkasteluaikavälillä yleisin syy tutkinnan aloittamiselle oli hyvän tilintarkastustavan tai tilintarkastuslain vastainen toiminta. Sanktiomuodoista varoituksia annettiin hieman enemmän kuin huomautuksia, hyväksymisen peruuttamiseen päädyttiin vain kahdeksassa tapauksessa. Yli puolessa tutkintatapauksissa sanktioita ei määrätty ollenkaan. Kaiken kaikkiaan sanktioiden ja tutkintatapausten määrässä ei havaittu tapahtuneen suurta vaihtelua tarkasteluaikavälillä.

Miniature Wulff-type generator for improving feed to fuel cells /|nT.-S. Tan. -- 260 St. Catharines, Ont. : [s. n.],

The original objective of this work was to provide a simple generator w.hich would produce hydrogen torLfuel-cell feed and which could be operated under remote or northern conditions. A secondary objective was to maximize the yield of hydrogen and carbon monoxide from available feed-stocks. A search of the patent literature has indicated that the concept of a small Wulff-type generator is essentially sound and that hydrogen may be recovered from a wide variety of hydrocarbon feed-stocks. A simple experimental set-up has been devised, patterned after ~~t originally used by R. G. Wulff for producing acetylene. This provides a supply of feed-stock, with or Without a carrier gas, which may be passed directly through a heated tube, which may contain a catalyst. A suitable procedure has been devised for analysi~ effluent gases for hydrogen, oxygen, nitrogen, methane and carbon monoxide by gas chromatography with the column packed with .Molecular .:>ieve .5 4. Athanol with air a.s carrier gas and at the same time as oxidant o was thermolyzed at temperatures in the ra~e 700-1100 C, with or Wi~lout catalyst. Methanol with or without nitrogen as a carrier gas was also cracked with • the same type of reactor refractory tube, but the temperature range was lower t down to ,300 " C when a catalyst was used. The problems of converting methane to hydrogen and carbon monoxide effiCiently, using air and/or water as oxidants were also studied.

Multinational drug corporations, intellectual property rights and the Canadian state : a historical and critical analysis

This study critically analyzes the historical role and influence of multinational drug cotpOrations and multinational corporations in general; the u.s. government and the Canadian state in negotiating the global recognition ofIntellectual Property Rights (IPR) under GATT/NAFTA. This process began in 1969 when the Liberal government, in response to high prices for brand-name drugs amended the Patent Act to introduce compulsory licensing by reducing monopoly protection from 20 to seven years. Although the financial position ofthe multinational drug industry was not affected, it campaigned vigorously to change the 1969 legislation. In 1987, the Patent Act was amended to extend protection to 10 years as a condition for free trade talks with the u.s. Nonetheless, the drug industry was not satisfied and accused Canada of providing a bad example to other nations. Therefore, it continued to campaign for global recognition ofIPR laws under GATT. Following the conclusion of the GATTI Trade-Related aspects of Intellectual Property Rights agreement (TRIPS) in 1991, the multinational drug industry and the American government, to the surprise of many, were still not satisfied and sought to implement harsher conditions under NAFTA. The Progressive Conservative government readily agreed without any objections or consideration for the social consequences. As a result, Bill C-91 was introduced. It abandoned compulsory licenses and was made retroactive from December 21, 1991. It is the contention of this thesis that the economic survival of multinational corporations on a global scale depends on the role and functions of the modem state. Similarly, the existence of the state depends on the ideological-political and socioeconomic assistance it gives to multinational corporations on a national and international scale. This dialectical relation of the state and multinational corporations is explored in our theoretical and historical analysis of their role in public policy.

Gideon Sundback fonds, 1942, 1952, 1985-1986, 1991, 2004, n.d.

Gideon Sundback was born in Stockholm, Sweden in 1880. He was educated as an engineer and settled in the United States in 1905. While working for the Universal Fastener Company, New Jersey in 1913 he developed and patented a “separable fastener”, which improved on an earlier version of what today is known as the zipper. He later moved his family to Meadville, Pennsylvania and sought a Canadian location for the production of his new invention. He settled on St. Catharines as it was an easy commute from his Pennsylvania home and opened The Lightning Fastener Company on Niagara Street. Sundback died on June 21, 1954 and is interred in Meadville, Pennsylvania. The plant continued to operate, but with increased foreign competition the manufacture of the zipper declined. The plant closed in 1981. Source: The St. Catharines Standard, July 3, 2004 Harold Fox was a noted lawyer, academic, businessman, author and a leading authority on intellectual property. He was engaged by Gideon Sunback and the Lightening Fastening Company to combat patent infringements by Colonial Fastener in the 1930s. The relationship continued when Fox was asked to become the managing director of the company, which he did until 1949. Fox lived in St. Catharines at his home “Foxcroft” until his death in 1969. Source: http://thefoxfund.com/harold.htm (November 2, 2009)

Henry Hope & Sons of Canada Ltd. Letter, 1916

Henry Hope & Sons of Canada Ltd. were located at 45 King Street West, Toronto, Ont. at the writing of this letter in 1916. The company specialized in “weathertight casements in iron steel or gun-metal, unbreakable steel windows, fanlight opening-gear, leaded lights and stained glass, patent glass roofing, locks and door furniture, rainwater goods in cast lead and cast iron”. The letter is addressed to Mr. H.Y. [Harry Young] Grant, c/o Fenwick Farm, Lundy’s Lane, Niagara Falls, Ont. from R.W. Smith. The letter is in reply to a query about casement windows. Harry Young Grant (1860-1934), son of Sir James Alexander Grant and Maria Malloch of Ottawa, Ont. was a medical doctor specializing in the treatment of the eye, ear, nose and throat. After his retirement he became a member of the Niagara Parks Commission. He was married to Grace A. Smith, daughter of James R. Smith of Buffalo.

Advertising broadsheet for the book "Real Pen-Work Self-Instructor in Penmanship", [1881]

One advertising broadsheet titled Private Suggestions and Instructions-to-Agents how to sell the Real Pen-Work Self-Instructor in Penmanship and Patent Ink Capsules. There are sections on how to order, how agents sell the inks, how to send money, and more.

James Corbin letter, October 2, 1813

James Corbin (1791-1860) lived in Williamstown, Berkshire County, Massachusetts. He is buried there is Southlawn cemetery. Pliny Moore (1759-1822) was the founder of the town of Champlain, New York. He served in the revolutionary war and after received the Smith and Graves patent, a parcel of land more than 11,000 acres in size. He served in several town offices in Champlain, including postmaster and judge, as well as operating sawmills and textile mills. Letter transcription: Dear Sir, The reason I did not come to tend your mill last spring was because the letter you wrote me dated 1 of March I didn’t receive it until the 12 of April and inform me that if I could be there in 2 or 3 weeks you would employ me as we agreed and therefore I concluded it would not do any good for me to come. It was a great disappointment to me because I was all ready to come whenever I got word. It is impossible for me to come now for I am in partnership with my brother in the farm and Mills and must take care our crops and settle our [bushels] this winter. I know nothing to the contrary but what I can come next spring I will let you know by uncle Corbin this winter. James Corbin

Letter - Nikola Tesla to William B. Rankine, 19 April 1904

A letter from Nikola Tesla to William B. Rankine in the year 1904. Tesla discusses the worth of his patents/companies. Tesla also remarks on the power of several of his machines including "Tesla Coil", "Tesla Transformer", and "Tesla High-Potential Methods".

Transferring Results of Behavioral Research to Industry to Improve Animal Welfare on the Farm, Ranch and the Slaughter Plant

The article focuses on three results of the study: "(1)Communicate your results outside the research. Write articles in popular and industry magazines. Speak at producer meetings and develop websites that can be used to transfer research results into practice. (2) Choose places (e.g. farms or plants) that have managers who believe in your research, and be prepared to spend a lot of time with the first place that uses your findings. (3) to fail. (4) Do not allow your technology to get tied up in patent disputes."