一种抗人免疫缺陷病毒Ⅰ型p24蛋白的单克隆抗体及其应用

一种抗人免疫缺陷病毒I型(HIV-1)p24蛋白的单克隆抗体及其应用，属生物技术领域。单克隆抗体的免疫原为HIV-1B亚型p24基因工程重组蛋白；是由免疫小鼠的脾细胞与骨髓瘤细胞融合产生的杂交瘤p3JB9、p5F1和p6F4细胞系分泌产生；属于免疫球蛋白IgG1型；与猴免疫缺陷病毒SIVAGM、猴逆转录D型病毒SRV交叉反应；与CCR5 嗜性病毒株HIVAda-M和耐药株HIV74V反应；p5F1和p6F4能与临床分离株HIVKM018反应，而 p3JB9不能与临床分离株HIVKM018反应。单克隆抗体可以与其它单克隆抗体或多克隆抗体组合，或可作放射性同位素、酶、荧光素化合物、化学发光化合物或胶体金属离子的标记，用于制备定性或定量检测各种体液、培养上清或细胞、组织中p24抗原的试剂。具有制备方法简单，效价高；单克隆抗体特异性强，灵敏度高。

Seaweeds: utilization and product applications

Seaweeds have been used as food, medicine, fertilizers, soil conditioner and source of salt. Realizing the potentials of seaweeds, research and development thrusts have been geared towards improving and developing its product applications. Today, various applications of seaweeds have been developed and improved. The major success in the seaweed industry is the development of phycocolloids with the following specific applications: 1) agar; 2) carrageenans; and, 3) alginates.

Face-based Selection of Corners in 3D Substructuring

In most recent substructuring methods, a fundamental role is played by the coarse space. For some of these methods (e.g. BDDC and FETI-DP), its definition relies on a 'minimal' set of coarse nodes (sometimes called corners) which assures invertibility of local subdomain problems and also of the global coarse problem. This basic set is typically enhanced by enforcing continuity of functions at some generalized degrees of freedom, such as average values on edges or faces of subdomains. We revisit existing algorithms for selection of corners. The main contribution of this paper consists of proposing a new heuristic algorithm for this purpose. Considering faces as the basic building blocks of the interface, inherent parallelism, and better robustness with respect to disconnected subdomains are among features of the new technique. The advantages of the presented algorithm in comparison to some earlier approaches are demonstrated on three engineering problems of structural analysis solved by the BDDC method.

Rebuilding the limit order book: Sequential Bayesian inference on hidden states

The limit order book of an exchange represents an information store of market participants' future aims and for many traders the information held in this store is of interest. However, information loss occurs between orders being entered into the exchange and limit order book data being sent out. We present an online algorithm which carries out Bayesian inference to replace information lost at the level of the exchange server and apply our proof of concept algorithm to real historical data from some of the world's most liquid futures contracts as traded on CME GLOBEX, EUREX and NYSE Liffe exchanges. © 2013 © 2013 Taylor & Francis.

OnceAS/Q:一个面向QoS的Web应用服务器

网络分布计算环境下应用系统的需求多样化和复杂性的增长,要求位于中间件层次的Web应用服务器(web application server,简称WAS)从原来的尽力而为服务模型转变为服务质量(quality of service,简称QoS)保障模型,为具有不同需求的应用分别提供适宜的服务质量保障.目前的WAS系统在此方面仍然比较薄弱.OnceAS/Q是一个面向QoS的WAS系统,它以QoS规约为基础,为不同应用提供不同的QoS保障能力.OnceAS/Q实现了一个应用QoS保障框架,提供了一组QoS服务组件支持具有QoS需求的应用开发和运行.介绍了OnceAS/Q的体系结构和主要组件,详细阐述了两个关键问题,一是QoS规约的定义及其映射,另一个是面向QoS的服务组件和资源的动态重配.OnceAS/Q原型在Ecperf测试基准下,对其QoS保障能力进行了实验.实验数据表明,在较大规模的应用环境下,OnceAS/Q能够提供更好的服务质量,并且开销是可接受的.

一种按基因重要度收敛的进化算法

提出基因重要度的概念,通过实验证明基因重要度对于单变量边缘分布算法(Unvaried Marginal Distribution Algo-rithm,UMOA)收敛的重要性.由此提出一种基于基因重要度的进化算法.该算法首先对组成染色体的各基因进行重要度排序,随后对重要度大的基因先进行收敛操作,每次收敛当前重要度最大的基因,直到所有基因全部收敛.实验数据表明,本算法的收敛速度更快,而且更容易求出满意解.

Broadly Tunable Grating-Coupled External Cavity Laser With Quantum-Dot Active Region

A broadly tunable and high-power grating-coupled external cavity laser with a tuning range of more than 200 nm and a similar to 200-mW maximum output power was realized, by utilizing a gain device with the chirped multiple quantum-dot (QD) active layers and bent waveguide structure. The chirped QD active medium, which consists of QD layers with InGaAs strain-reducing layers different in thickness, is beneficial to the broadening of the material gain spectrum. The bent waveguide structure and facet antireflection coating are both effective for the suppression of inner-cavity lasing under large injection current.

Multifunctional metallophosphors with anti-triplet–triplet annihilation properties for solution-processable electroluminescent devices

With the goal to provide organometallic triplet emitters with good hole-injection/hole-transporting properties, highly amorphous character for simple solution-processed organic light-emitting diodes, and negligible triplet-triplet (T-T) annihilation, a series of new phosphorescent cyclometalated Ir-III and Pt-II complexes with triphenylamine-anchored fluorenylpyridine dendritic ligands were synthesized and characterized. The photophysical, thermal, electrochemical and electroluminescent properties of these molecules are reported.