973 resultados para Non-professional interpreting
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The goal of the present paper is to analyse the classic entrepreneurship strategies (Innovation, Risk and Proactivity) in small and medium-sized businesses. However as presented in the title, the study will go further by comparing the results of those strategies in familiar and nonfamiliar businesses. This study was carried on in construction and industry sectors, in the region of Vale do Sousa, in the north of Portugal. In order to classify businesses as familiar or non-familiar types two criterion were adopted: (1) Management Control, (2) Family Employability. On the opposite to some studies that present a larger percentage of familiar businesses in national and European entrepreneurial fabric, the criterion used leaded to a larger number of non-familiar businesses (53%). The results showed that in general SMEs in this region are not following entrepreneurship strategies. Analysing the entire sample without a separation of businesses by nature (familiar/non-familiar) only proactivity showed to be more present in the managerial decisions. There is a lack of innovation and risk culture. Comparing the groups only on proactivity tests was possible to verify some differences. It was concluded that non-familiar businesses are more proactive than familiar ones. Between those groups there are no statistical differences on the means of the variables innovation and risk. At the same time some tests were conducted to test the differences on the variable entrepreneurship. The results were similar to innovation and risk strategies: There are no significant differences on entrepreneurship between these groups of businesses.
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O estudo caso apresentado neste artigo aborda a colaboração entre profissionais de múltiplas áreas disciplinares. Este estudo descreve como foi realizada a parceria entre a equipa de enfermagem e a equipa de psicologia clinica nas visitas domiciliárias com familias em risco. Igualmente, discute as dificuldades enfrentadas quando os profissionais não partilhavam os mesmos modelos de praticas colaborativas.
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European Cetacean Society Conference Workshop, Galway, Ireland, 25th March 2012.
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In the last years it has become increasingly clear that the mammalian transcriptome is highly complex and includes a large number of small non-coding RNAs (sncRNAs) and long noncoding RNAs (lncRNAs). Here we review the biogenesis pathways of the three classes of sncRNAs, namely short interfering RNAs (siRNAs), microRNAs (miRNAs) and PIWI-interacting RNAs (piRNAs). These ncRNAs have been extensively studied and are involved in pathways leading to specific gene silencing and the protection of genomes against virus and transposons, for example. Also, lncRNAs have emerged as pivotal molecules for the transcriptional and post-transcriptional regulation of gene expression which is supported by their tissue-specific expression patterns, subcellular distribution, and developmental regulation. Therefore, we also focus our attention on their role in differentiation and development. SncRNAs and lncRNAs play critical roles in defining DNA methylation patterns, as well as chromatin remodeling thus having a substantial effect in epigenetics. The identification of some overlaps in their biogenesis pathways and functional roles raises the hypothesis that these molecules play concerted functions in vivo, creating complex regulatory networks where cooperation with regulatory proteins is necessary. We also highlighted the implications of biogenesis and gene expression deregulation of sncRNAs and lncRNAs in human diseases like cancer.
The use of non-standard CT conversion ramps for Monte Carlo verification of 6 MV prostate IMRT plans
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Monte Carlo (MC) dose calculation algorithms have been widely used to verify the accuracy of intensity-modulated radiotherapy (IMRT) dose distributions computed by conventional algorithms due to the ability to precisely account for the effects of tissue inhomogeneities and multileaf collimator characteristics. Both algorithms present, however, a particular difference in terms of dose calculation and report. Whereas dose from conventional methods is traditionally computed and reported as the water-equivalent dose (Dw), MC dose algorithms calculate and report dose to medium (Dm). In order to compare consistently both methods, the conversion of MC Dm into Dw is therefore necessary. This study aims to assess the effect of applying the conversion of MC-based Dm distributions to Dw for prostate IMRT plans generated for 6 MV photon beams. MC phantoms were created from the patient CT images using three different ramps to convert CT numbers into material and mass density: a conventional four material ramp (CTCREATE) and two simplified CT conversion ramps: (1) air and water with variable densities and (2) air and water with unit density. MC simulations were performed using the BEAMnrc code for the treatment head simulation and the DOSXYZnrc code for the patient dose calculation. The conversion of Dm to Dw by scaling with the stopping power ratios of water to medium was also performed in a post-MC calculation process. The comparison of MC dose distributions calculated in conventional and simplified (water with variable densities) phantoms showed that the effect of material composition on dose-volume histograms (DVH) was less than 1% for soft tissue and about 2.5% near and inside bone structures. The effect of material density on DVH was less than 1% for all tissues through the comparison of MC distributions performed in the two simplified phantoms considering water. Additionally, MC dose distributions were compared with the predictions from an Eclipse treatment planning system (TPS), which employed a pencil beam convolution (PBC) algorithm with Modified Batho Power Law heterogeneity correction. Eclipse PBC and MC calculations (conventional and simplified phantoms) agreed well (<1%) for soft tissues. For femoral heads, differences up to 3% were observed between the DVH for Eclipse PBC and MC calculated in conventional phantoms. The use of the CT conversion ramp of water with variable densities for MC simulations showed no dose discrepancies (0.5%) with the PBC algorithm. Moreover, converting Dm to Dw using mass stopping power ratios resulted in a significant shift (up to 6%) in the DVH for the femoral heads compared to the Eclipse PBC one. Our results show that, for prostate IMRT plans delivered with 6 MV photon beams, no conversion of MC dose from medium to water using stopping power ratio is needed. In contrast, MC dose calculations using water with variable density may be a simple way to solve the problem found using the dose conversion method based on the stopping power ratio.
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Dissertação apresentada à Escola Superior de Educação de Lisboa para obtenção de grau de mestre em Ciências da Educação - Especialidade Educação Especial
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Non-suicidal self-injury (NSSI) is the deliberate, self-inflicted destruction of body tissue without suicidal intent and an important clinical phenomenon. Rates of NSSI appear to be disproportionately high in adolescents and young adults, and is a risk factor for suicidal ideation and behavior. The present study reports the psychometric properties of the Impulse, Self-harm and Suicide Ideation Questionnaire for Adolescents (ISSIQ-A), a measure designed to comprehensively assess the impulsivity, NSSI behaviors and suicide ideation. An additional module of this questionnaire assesses the functions of NSSI. Results of Confirmatory Factor Analysis (CFA) of the scale on 1722 youths showed items' suitability and confirmed a model of four different dimensions (Impulse, Self-harm, Risk-behavior and Suicide ideation) with good fit and validity. Further analysis showed that youth׳s engagement in self-harm may exert two different functions: to create or alleviate emotional states, and to influence social relationships. Our findings contribute to research and assessment on non-suicidal self-injury, suggesting that the ISSIQ-A is a valid and reliable measure to assess impulse, self-harm and suicidal thoughts, in adolescence.
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É do conhecimento geral que muitos professores ensinam os alunos a ouvir, cantar e compor, mas usam testes escritos para avaliar as aprendizagens. Este facto revela que, por um lado, há quem tenha a ideia que os testes escritos estão mesmo a avaliar as práticas musicais e, por outro lado, também há quem considere que é muito difícil e inconsistente avaliar as práticas musicais porque a Música tem um carácter transitório, efémero, imaterial. Além do problema ser interessante, ele é abrangente porque existe tanto entre os professores especialistas de Música como entre os professores generalistas de Educação de Infância e de 1º Ciclo. A experiência levada a cabo nos últimos três anos no Mestrado em Ensino de Educação Musical no Ensino Básico sobre a forma de avaliar as aprendizagens dos alunos em Educação Musical mantém os testes escritos para avaliar os conhecimentos teóricos, mas introduz um instrumento de avaliação das práticas musicais, as grelhas de descritores de desempenho. Estas grelhas, ainda que mantendo princípios orientadores comuns, são sempre feitas à medida para cada situação específica de obra, atividade musical, alunos e são aplicadas não só em observação direta, mas também sobre registos áudio/vídeo. Estes instrumentos são construídos pelos docentes e não em conjunto com os alunos, mas são-lhes apresentados e explicados desde o início de cada unidade didática, usados regulamente para autoavaliação formativa e nas apresentações finais para avaliação sumativa. Desta forma os alunos sabem desde o início onde se espera que cheguem e sabem em cada momento do processo em que ponto se encontram e que problemas/dificuldades musicais devem ser ultrapassados. Em cada atividade comparámos a autoavaliação dos alunos com a avaliação dos professores e verificámos em todas as situações uma elevada correlação positiva (r > 0,9). Teremos ainda que consolidar os dados já obtidos pelo que esperamos o envolvimento de mais professores. A possibilidade de divulgar a solução aqui apresentada, nomeadamente, através de ações de formação contínua, permitirá um evidente aumento da consistência e fiabilidade da avaliação das práticas musicais em Educação Musical.
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There are several hazards in histopathology laboratories and its staff must ensure that their professional activity is set to the highest standards while complying with the best safety procedures. Formalin is one of the chemical hazards to which such professionals are routinely exposed. To decrease this contact, it is suggested that 10% neutral buffered liquid formalin (FL) is replaced by 10% formalin-gel (FG), given the later reduces the likelihood of spills and splashes, and decreased fume levels are released during its handling, proving itself less harmful. However, it is mandatory to assess the effectiveness of FG as a fixative and ensure that the subsequent complementary techniques, such as immunohistochemistry (IHC), are not compromised. Two groups of 30 samples from human placenta have been fixed with FG and FL fixatives during different periods of time (12, 24, and 48 hours) and, thereafter, processed, embedded, and sectioned. IHC for six different antibodies was performed and the results were scored (0–100) using an algorithm that took into account immunostaining intensity, percentage of staining structures, non-specific immunostaining, contrast, and morphological preservation. Parametric and non-parametric statistical tests were used (alpha = 0•05). All results were similar for both fixatives, with global score means of 95•36±6•65 for FL and 96•06±5•80 for FG, and without any statistical difference (P>0•05). The duration of the fixation had no statistical relevance also (P>0•05). So it is proved here FG could be an effective alternative to FL.
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The present study, covering students from public schools and a private school on the island of São Miguel (Azores, Portugal), aims to meet the difficulties of the students of the 3rd and 4th years of the primary education in solving tasks involving construction, reading and interpreting tables and statistical graphs, in the context of Organization and Data Handling (ODH). We present the main results obtained from statistical methods, among which we highlight some non-parametric hypothesis tests and the Categorical Principal Component Analysis (CatPCA), given the nature of the variables included in the questionnaire (mostly nominal and ordinal variables).
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Tomar consciência do papel do educador de infância e do professor do 1º CEB manifesta-se uma tarefa essencial à prática, permitindo uma orientação da intervenção educativa, no sentido de ir ao encontro do que é esperado por parte destes profissionais. O trabalho espelha as experiências nos contextos de 1º Ciclo do Ensino Básico e de Educação Pré-Escolar, sendo que se encontram evidenciadas as especificidades, transversalidade e continuidade existentes em ambos os contextos. A abordagem do estudo apresenta um caráter misto. Isto é, por um lado um caráter qualitativo, na medida em que procuramos perceber mecanismos, comportamentos e atitudes, por outro lado um caráter quantitativo, na medida em que a informação, recolhida através dos questionários e entrevistas, pode espelhar uma perspetiva quantitativa. O trabalho, comum a ambas as valências, com vista a um incremento na melhoria da intervenção educativa, visa compreender as necessidades, motivações e comportamentos dos sujeitos de estudo. Este estudo tem caraterísticas próximas de uma investigação-ação que permitiram uma avaliação constante da intervenção com o objetivo de a tornar mais eficaz. Os instrumentos e técnicas de investigação utilizados foram a análise documental, as listas de verificação ou controlo, as grelhas de observação, a observação participante, os registos de observação, o inquérito por questionário, a entrevista, os instrumentos de avaliação das aprendizagens, o portfólio de criança, o registo de projeto lúdico e arede curricular. O conhecimento dos grupos de crianças permite atitudes adequadas, assim como uma planificação mais eficaz, na medida em que são promovidas atividades significativas e diferenciadas que vão de encontro às necessidades e interesses de cada um. Estes reguladores da prática educativa são instrumentos que permitem a reflexão, prática sine-qua-non para uma intervenção de qualidade, pois esta ação vai permitir uma avaliação dos acontecimentos e suas consequências e, ainda, a remodelação de práticas e atitudes.
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Conferência: 39th Annual Conference of the IEEE Industrial-Electronics-Society (IECON) - NOV 10-14, 2013
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Screening of topologies developed by hierarchical heuristic procedures can be carried out by comparing their optimal performance. In this work we will be exploiting mono-objective process optimization using two algorithms, simulated annealing and tabu search, and four different objective functions: two of the net present value type, one of them including environmental costs and two of the global potential impact type. The hydrodealkylation of toluene to produce benzene was used as case study, considering five topologies with different complexities mainly obtained by including or not liquid recycling and heat integration. The performance of the algorithms together with the objective functions was observed, analyzed and discussed from various perspectives: average deviation of results for each algorithm, capacity for producing high purity product, screening of topologies, objective functions robustness in screening of topologies, trade-offs between economic and environmental type objective functions and variability of optimum solutions.