Letters to a christian friend on the fundamental truths of Judaism

by Clementina de Rothschild. Transl. from the German [[Elektronische Ressource]]

Folding protein models with a simple hydrophobic energy function: The fundamental importance of monomer inside/outside segregation

The present study explores a “hydrophobic” energy function for folding simulations of the protein lattice model. The contribution of each monomer to conformational energy is the product of its “hydrophobicity” and the number of contacts it makes, i.e., E(h⃗, c⃗) = −Σi=1N cihi = −(h⃗.c⃗) is the negative scalar product between two vectors in N-dimensional cartesian space: h⃗ = (h1, … , hN), which represents monomer hydrophobicities and is sequence-dependent; and c⃗ = (c1, … , cN), which represents the number of contacts made by each monomer and is conformation-dependent. A simple theoretical analysis shows that restrictions are imposed concomitantly on both sequences and native structures if the stability criterion for protein-like behavior is to be satisfied. Given a conformation with vector c⃗, the best sequence is a vector h⃗ on the direction upon which the projection of c⃗ − c̄⃗ is maximal, where c̄⃗ is the diagonal vector with components equal to c̄, the average number of contacts per monomer in the unfolded state. Best native conformations are suggested to be not maximally compact, as assumed in many studies, but the ones with largest variance of contacts among its monomers, i.e., with monomers tending to occupy completely buried or completely exposed positions. This inside/outside segregation is reflected on an apolar/polar distribution on the corresponding sequence. Monte Carlo simulations in two dimensions corroborate this general scheme. Sequences targeted to conformations with large contact variances folded cooperatively with thermodynamics of a two-state transition. Sequences targeted to maximally compact conformations, which have lower contact variance, were either found to have degenerate ground state or to fold with much lower cooperativity.

Lectures on the religion of the Semites. First series. The fundamental institutions.

"Only nine lectures of the eleven were read in Aberdeen, the last two having been added to complete the discussion of sacrificial ritual."--Pref.

The fundamental issue: documents and marginal notes on the University of California loyalty oath.

Cover-title.

Operative masonry; or, A theoretical and practical treatise of building; containing a scientific account of stones, clays, bricks, mortars, cements, &c.; a description of their component parts, with the manner of preparing and using them. The fundamental rules in geometry, on masonry and stone-cutting, with their application to practice. Illustrated with forty copper-plate engravings.

Republished in 1846 with title: Practical masonry: or A theoretical and operative treatise of building ...

Getting started with power tools; a basic readily understandable book on the fundamental operations of power-tool equipment.

Mode of access: Internet.

Chemistry and food preparation, a laboratory manual for students of home economics; a series of experiments in elementary chemistry and experimental cookery designed for a scientific approach to the study of food preparation. Basic recipes and methods of combining ingredients are presented, together with variations that suggest the wide applicability of the fundamental principles.

Bibliography: p. 1

A treatise of algebra, in three parts : containing I. The fundamental rules and operations. II. The composition and resolution of equations of all degrees; and the different affections of their roots. III. The application of algebra and geometry to each other : to which is added, an appendix, concerning the general properties of geometrical lines /

Mode of access: Internet.

Navigation or, the Art of Sailing upon the sea : containing a demonstration of the Fundamental principles of this art together with all the practical rules of computing a ship's way both by plain sailing, mercator, and Middel Latitude founded upon the foregoing principles with many other useful things hereto belonging to which are added several necessary tables.

A journal of a voyage in the sweepstakes from the Lizard las 49 55 N. Lon. 12 56 to Jamaica Lat. 180 N Long. 3017 in the year 1754, p. 131-216 ; A table of Logarithmic sines, cosines, tangents and cotangents, [120] p.

An essay on the relation of the several parts of a mathematical science to the fundamental idea therein contained; the substance of which was read before the Ashmolean Society on the evening of May 14, 1849,

Mode of access: Internet.

PERT fundamentals; the fundamental concepts and techniques of PERT presented in a programed instruction format.

v. 1. Networking.- v. 2. Scheduling and planning.- v. 3. Workbook.

The elements of Biblical interpretation, containing a brief exposition of the fundamental principles and rules of this science.

Mode of access: Internet.

The problem of human life : containing the fundamental principles of the substantial philosophy; with a review of the six great modern scientists: Darwin, Tyndall, Huxley, Haeckel, Helmholtz, and Mayer ... /

Printed in two columns.

The fundamental concepts of physics in the light of modern discovery; three lectures at the Carnegie Institute of Technology, Pittsburgh, January, 1925,

"References": p. 110-112.