Insulin resistance does not play a major role in lipid and apolipoprotein profile in obese women

Background: Obesity is associated with increased atherogenesis through alterations in lipids, among other potential factors. Some of those abnormalities might be mediated by insulin resistance (IR). Aims: To compare lipid and apolipoprotein profile between lean and obese women; to evaluate the influence of IR on lipid and apolipoprotein profile, in obese women. Methods: We studied 112 obese and 100 normal-weight premenopausal women without known cardiovascular disease. Both groups were characterized for anthropometrics and a fasting blood sample was collected for assessment of glucose, insulin, triglycerides, cholesterol (total, LDL and HDL), and apolipoproteins A-I, A-II, B, C-II, C-III, and E; IR was assessed by the homeostatic model assessment (HOMA-IR). We compared lipids between obese and lean women; we looked for correlation of those levels with anthropometrics and IR (independently from anthropometrics) in obese women. Results: Obese women were characterized by mean age=34.6±8.3 years, BMI=43.6±7.9 kg/m2, waist circumference (Wc)=117.5±15.1 cm, and HOMA-IR=4.28±3.5. Lean women (age=34.2±8.3 years, BMI=21.4±1.7 kg/m2, Wc=71.7±5.8 cm, and HOMA-IR=1.21±0.76) presented with significantly lower levels of total cholesterol (P=0.001), LDL-cholesterol (P<0.001), and triglycerides (P<0.001); they presented higher levels of HDL-cholesterol (P<0.001), Apo A-I (P<0.001) and Apo A-II (P=0.037). HOMA-IR showed no significant association with apolipoproteins. HOMA-IR was inversely associated with HDL-cholesterol (P=0.048; r=−0.187) but that association disappeared when we adjusted for waist circumference. Only triglycerides were directly associated with HOMA-IR (P<0.001; r=0.343) independently from anthropometrics. Conclusion: We confirm that obese women present worst lipid and apolipoprotein profile. However, with the exception for triglycerides, insulin resistance per se does not play a major role in lipid and apolipoprotein abnormalities observed in obese women.

A palavra do corpo em João Mota : um estudo sobre a presença, o corpo e a palavra nos espetáculos "Cyrano de Bergerac" e "Play Strindberg" : dissertação

Dissertação submetida à Escola Superior de Teatro e Cinema para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Artes Performativas - especialização em Interpretação

PLAY: terminal IPTV para visualização de sessões de colaboração multimédia

Dissertação de Mestrado em Engenharia Informática

Do Spirituality and Faith Make a Difference? Report from the Southern European Psycho-Oncology Study Group

OBJECTIVE: In the last decade, some attention has been given to spirituality and faith and their role in cancer patients' coping. Few data are available about spirituality among cancer patients in Southern European countries, which have a big tradition of spirituality, namely, the Catholic religion. As part of a more general investigation (Southern European Psycho-Oncology Study--SEPOS), the aim of this study was to examine the effect of spirituality in molding psychosocial implications in Southern European cancer patients. METHOD: A convenience sample of 323 outpatients with a diagnosis of cancer between 6 to 18 months, a good performance status (Karnofsky Performance Status > 80), and no cognitive deficits or central nervous system (CNS) involvement by disease were approached in university and affiliated cancer centers in Italy, Spain, Portugal, and Switzerland (Italian speaking area). Each patient was evaluated for spirituality (Visual Analog Scale 0-10), psychological morbidity (Hospital Anxiety and Depression Scale--HADS), coping strategies (Mini-Mental Adjustment to Cancer--Mini-MAC) and concerns about illness (Cancer Worries Inventory--CWI). RESULTS. The majority of patients (79.3%) referred to being supported by their spirituality/faith throughout their illness. Significant differences were found between the spirituality and non-spirituality groups (p ≤ 0.01) in terms of education, coping styles, and psychological morbidity. Spirituality was significantly correlated with fighting spirit (r = -0.27), fatalism (r = 0.50), and avoidance (r = 0.23) coping styles and negatively correlated with education (r = -0.25), depression (r = -0.22) and HAD total (r = -0.17). SIGNIFICANCE OF RESULTS: Spirituality is frequent among Southern European cancer patients with lower education and seems to play some protective role towards psychological morbidity, specifically depression. Further studies should examine this trend in Southern European cancer patients.

Expanding the magic circle in pervasive casual play

Dissertação para obtenção do Grau de Doutor em Informática

Wireless triple play system

Dissertação para obtenção do Grau de Mestre em Engenharia Electrotécnica e Computadores

Canada, a child's play

Science4you, a Portuguese developer, producer and seller of scientific and educational toys, leveraged the worldwide growth of this category to successfully expand its operations abroad. Following a recent entry into the United States market, the purpose of this report is to help the company define the next step in its international expansion. A customized scoring model, based on a set of relevant macro and micro-criteria was developed for Anglo-Saxon and Asian countries, yielding Canada as the market with the highest potential. The recommended entry mode is direct exporting via an independent distributor, being complemented with a financial and risk analysis.

Record, play, go…

This workshop aims at stimulating children’s oral language skills by involving them on playing and creating different language games or activities using the t-stories interface. The interface allows recording and playing audio on the stories’ modules, as well as recording and playing based on identification with NFC tags that can be used as sticker on objects, paper, or other materials and placed in different locations. After the presentation of t-stories by the workshop facilitators, children will have the opportunity to explore the interface on their own, then they will be asked to participate in different language games, whereby they actively create their own content. Afterwards children will be challenged to imagine and create activities for their peers.

A supervisão pedagógica como prática de transformação: o lugar das narrativas profissionais

Este texto tem como objetivo discutir o lugar das narrativas profissionais, de natureza autobiográfica, produzidas por professores em contexto de formação pós-graduada em supervisão pedagógica. Começando pela discussão do conceito de qualidade em educação, e que radica numa concepção de educação para o desenvolvimento sustentável e para a transformação de pessoas e de contextos, a autora passa para uma análise do papel dos professores no desenvolvimento de práticas pedagógicas de qualidade. Embora os contextos de educação e de formação tenham um papel determinante, os professores, principalmente através das expectativas que detêm face aos seus alunos, têm um papel crucial no combate a formas de discriminação e de exclusão nas escolas. O conceito de supervisão que informa este texto também se coloca ao serviço da qualidade em educação enunciada, ao ser tomado enquanto teoria e prática de regulação crítica e colaborativa da pedagogia e do desenvolvimento profissional, numa visão da educação para a transformação e para a sustentabilidade. O texto finaliza com a ilustração do modo como as narrativas profissionais se constituem enquanto estratégias de autossupervisão do trabalho docente num contexto de formação pós-graduada. Desenvolvidas em contextos profissionais, e estabelecendo pontes entre o conhecimento acadêmico e experiencial, elas incidem na análise dos modos como o trabalho docente se coloca (ou não) ao serviço de uma pedagogia e de um desenvolvimento profissional docente assente em valores de sustentabilidade e de transformação, identificando os constrangimentos estruturais e apontando rumos de ação.

Final report - EngageBook: touch, read and play

This  report  intends  to  give  a  detailed  notion  about  the  entire  project  development  from  its  publications to communications; from the workshops to the software and BridgingBook patent. To make it clear we followed the Tasks timeline as presented in our proposal, adjusting dates, when they were changed. Because we followed a double take in prototyping/software development, we will also repeat some of the tasks in order to give information about each different phase and its dimensions, in an autonomous way.

Children's play and leisure : connections with emotional competence

O jogo e o lazer são elementos importantes para o desenvolvimento das crianças. O objetivo geral desta tese foi o de investigar o modo como o jogo e o lazer estão relacionados com diferentes aspetos das competências emocional e social das crianças e jovens. Nesta tese foram investigados três aspetos do jogo: o tempo, a forma e o nível social, diferentes formas de lazer, e vários elementos chave do funcionamento sócio-emocional, através da combinação de observações naturalistas, tarefas, questionários e de um método inovador de mensuração, baseado em Identificação por Rádio-Frequência. O panorama que surge dos estudos incluídos nesta tese é que o jogo e o lazer estão relacionados com o funcionamento sócio-emocional, embora de formas distintas, e por vezes inesperadas. Os estudos no recreio revelaram que as crianças envolvem-se predominantemente no jogo de atividade física. Contudo, enquanto que uma forma de jogo de atividade física, o jogo de exercício, foi associado a melhor competência social, a outra forma, o jogo de luta-e-perseguição, foi associado à agressividade. O facto de o jogo de faz-de-conta, em estudos anteriores, ter sido maioritariamente estudado em espaços interiores, pode explicar o porquê das associações negativas encontradas entre o jogo de faz-de-conta, quer em grupo, quer solitário (nas raparigas) e a competência sócio-emocional, que contrastam com a literatura. De facto, as crianças que não conseguem juntar-se aos seus pares no jogo de exercício podem optar por esta alternativa, o que sugere que crianças socialmente competentes poderão retirar maior vantagem das oportunidades existentes, adaptando melhor os seus comportamentos de jogo. As crianças mais velhas têm geralmente mais liberdade de decisão sobre o seu tempo de lazer. Quando perguntámos às crianças mais velhas e aos adolescentes como passavam a sua semana, as atividades de ecrã destacaram-se. Contudo, as atividades de ecrã e as atividades intelectuais foram relacionadas a mais problemas de saúde mental, enquanto que as atividades desportivas foram associadas a melhor saúde mental. Concluindo, diferentes formas de jogo e de lazer podem ter diferentes funções, de uma forma positiva ou negativa, dependendo da situação em que a criança se encontra.

Equilibrium play and best response to (Stated) beliefs in constant sum games

We report experimental results on one-shot two person 3x3 constant sum games played by non-economists without previous experience in the laboratory. Although strategically our games are very similar to previous experiments in which game theory predictions fail dramatically, 80% of actions taken in our experiment coincided with the prediction of the unique Nash equilibrium in pure strategies and 73% of actions were best responses to elicited beliefs. We argue how social preferences, presentation effects and belief elicitation procedures may influence how subjects play in simple but non trivial games and explain the diferences we observe with respect to previous work.

Prévention des alcoolisations aiguës a l'adolescence: quel rôle pour le médecin de famille [Prevention of binge drinking in adolescents: do family doctors have a role to play?].

Binge drinking has nearly become the norm for young people and is thus worrying. Although alcohol use in males attracts more media attention, females are also frequently affected. A variety of preventive measures can be proposed: at the individual level by parents, peers and family doctors; at the school and community level, particularly to postpone age of first use and first episode of drunkenness; at the structural level through a policy restricting access to alcohol for young people and increasing its price. Family doctors can play an important role in identifying at risk users and individualising preventive messages to which these young people are exposed in other contexts.

Four-month-olds make triangular bids to father and mother during trilogue play with still-face

(from the journal abstract) A new observational procedure, Trilogue Play with Still-face, revealed 4-month-olds' capacities to address both their fathers and mothers, by rapidly shifting gaze and affect between them. Infants were observed in four interactive contexts: (1) '3-together' play with both parents; (2) '2 + 1' play with one parent engaging and the other as third party; (3) the same, with one parent posing a still-face; (4) '3-together' play. Infants were able to discriminate between the four contexts. They coordinated three social poles of attention in each one. Their affect configurations were context sensitive. These findings demonstrate the infant's social capacities for triangular, three-person interactions, in addition to dyadic, two-person, and triadic, two-person plus object, ones. They support a view of intersubjectivity as primary and point to a promising field of investigation for the study of family process. (PsycINFO Database Record (c) 2005 APA, all rights reserved)