990 resultados para Total migration downtime
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This paper presents the "state of the art" and some of the main issues discussed in relation to the topic of transnational migration and reproductive work in southern Europe. We start doing a genealogy of the complex theoretical development leading to the consolidation of the research program, linking consideration of gender with transnational migration and transformation of work and ways of survival, thus making the production aspects as reproductive, in a context of globalization. The analysis of the process of multiscale reconfiguration of social reproduction and care, with particular attention to its present global dimension is presented, pointing to the turning point of this line of research that would have taken place with the beginning of this century, with the rise notions such as "global care chains" (Hochschild, 2001), or "care drain" (Ehrenreich and Hochschild, 2013). Also, the role of this new agency, now composed in many cases women who migrate to other countries or continents, precisely to address these reproductive activities, is recognized. Finally, reference is made to some of the new conceptual and theoretical developments in this area.
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This article discusses the challenges of irregular migration for the security of the EU. They are analyzed starting with the European Security Strategy 2003, and the Report on its Implementation, 2008, and notes many failures: The EU Members did not follow the directives adopted in Brussels, the mismanagement of migration and asylum policies, and numerous actions that can be characterized or described as improvised, scattered or irresponsible. The 2016 Global Strategy recognizes these failures and call attention to the European leaders to reconsider how the EU functions and operates, suggesting the need for greater unity and cooperation to achieve a more effective migration policy. However, the article points out that practically all of the sections of the new Strategy dealing with migration were already embodied in previous Strategies, and stress that in parallel with the publication of the 2016 Global Strategy, actions are already undertaken, such as the EU readmission agreements signed with several important third countries of origin.
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Le nombre d’étudiantes et étudiants participant à une mobilité internationale étudiante a considérablement augmenté au cours des dernières années. Dans le contexte de la mondialisation, les activités d’internationalisation sont devenues une priorité des établissements d’enseignement (Association des collèges communautaires du Canada, 2010a). Le recrutement des étudiantes et étudiants étrangers apporte plusieurs avantages au pays et à l’établissement d’accueil (Ibid.). De ce fait, pour favoriser ce recrutement et la mobilité internationale étudiante, les gouvernements ont mis en place des politiques d’immigration et les universités ont signé différentes alliances et accords bilatéraux entre elles. Toutefois, si les mobilités se font principalement vers les pays industrialisés (Lerot, 2001), le Canada est en retard sur sa proportion de personnes étudiantes effectuant une mobilité internationale étudiante dans ses collèges et universités (Association des collèges communautaires du Canada, 2010b). De même que le Québec qui voit sa proportion de l’effectif total de ses étudiantes et étudiants étrangers diminuer, alors que celle-ci augmente dans les autres régions du Canada (McMullen et Élias, 2011). À cet effet, les universitaires représentent la majorité des étudiantes et étudiants étrangers au Québec (Gouvernement du Québec, 2014a), mais la proportion globale d’universitaires internationaux diffère selon le type de région. En ce sens, celle-ci est la moins élevée dans les régions intermédiaires et la plus élevée dans les régions centrales (Gouvernement du Québec, 2013, 2014b, 2015), alors que ces régions sont toutes deux des grands centres de population. Ainsi, pour contribuer à mieux saisir ce que recouvre cette moins grande attractivité des régions intermédiaires, la question générale de recherche est : quels sont les motifs de choix, à chacune des dimensions du choix du lieu d’étude, d’effectuer une mobilité internationale étudiante dans une université située en région intermédiaire au Québec ? Pour répondre à cette question, et en se basant sur un cadre d’analyse à deux dimensions et sur l’état de connaissances à ce sujet, quatre objectifs spécifiques sont définis : 1) décrire les motifs de migration pour études, 2) examiner les associations entre les motifs de choix dans chaque catégorie pour y déceler d’éventuels regroupements sous-jacents, 3) examiner les associations entre ces regroupements de motifs et les caractéristiques des personnes étudiantes (âge, sexe, pays d’origine, domaine d’études, etc.), 4) déterminer si le choix de l’établissement d’accueil se fait avant ou après le choix du pays d’accueil. Pour y répondre, une recherche quantitative descriptive corrélationnelle, utilisant une analyse d’interdépendance (analyse factorielle), est menée, à l’aide d’un questionnaire anonyme disponible en ligne qui intègre plusieurs échelles de mesure, auprès des universitaires internationaux inscrits pour la première fois à l’Université de Sherbrooke à l’automne 2014. Au total, l’échantillon se compose de 141 universitaires internationaux. Ils sont âgés de 17 à 29 ans, proviennent des différents domaines, cycles et régimes d’études et il y a autant d’hommes que de femmes qui composent l’échantillon. De plus, les trois quarts de l’échantillon sont originaires de la France. L’analyse des données recueillies dans le questionnaire montre que l’importance accordée aux items du questionnaire représentant les motifs de migration pour études varie selon les dimensions du choix du lieu d’étude et qu’il existe des écarts dans les résultats. Synthétisés en facteurs, les résultats font ressortir trois facteurs liés au pays d’origine qui interviennent dans le choix d’étudier à l’international : 1) PO_La pauvreté de l’enseignement, 2) PO_Les contextes politiques et économiques, 3) PO_Les politiques d’éducation, et quatre facteurs personnels qui interviennent dans ce choix : 1) PER_le désir d’exploration, 2) PER_Le désir de changement, 3) PER_Les considérations familiales, 4) PER_Les aspirations personnelles et professionnelles. Aussi, il y a sept facteurs de choix du pays d’accueil : 1) PA_Les perspectives d’avenir, 2) PA_L’information disponible, 3) PA_Le dépaysement, 4) PA_Les considérations culturelles, 5) PA_Les liens au pays d’origine et la sécurité, 6) PA_Le cadre financier et environnemental, 7) PA_Les relations sociales. Puis, les résultats décrivent quatre facteurs de choix de l’établissement d’accueil : 1) EA_Les services de l’établissement, 2) EA_La qualité de la formation offerte, 3) EA_L’accessibilité et l’ouverture, 4) EA_Les possibilités d’emploi et les partenariats. Parmi l’ensemble de ces facteurs, seul deux d’entre eux, PER_Le désir d’exploration et PA_Le dépaysement, ont en moyenne une importance élevée dans le choix des universitaires internationaux d’étudier en région intermédiaire au Québec, alors que les facteurs liés au pays d’origine ont quant à eux, de manière générale, peu ou pas d’influence. Toutefois, il existe des écarts parmi les personnes répondantes à l’étude et les résultats montrent la présence d’associations entre certains facteurs et des caractéristiques des personnes étudiantes, soit la nature de l’expérience à international, la durée du séjour et la provenance des répondantes et répondants selon la typologie économique et sociale des pays du monde, ce qui laisse supposer la présence de groupe parmi les personnes répondantes à l’étude. Ainsi, les différents résultats de l’étude pourraient servir de guide aux conseillers et conseillères d’orientation du Québec, intervenant auprès des universitaires internationaux en région intermédiaire dans cette province, ainsi qu’aux universités situées dans ces régions. En effet, ces résultats pourraient influencer la pratique des conseillers et conseillères d’orientation du Québec quant au principal défi des universitaires internationaux, et les universités pourraient adapter leurs stratégies de recrutement selon l’importance accordée aux différents facteurs de migration pour études et ainsi attirer un plus grand nombre d’étudiantes et étudiants étrangers.
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A detailed study of the early life of fishes forms one of the very important aspects with respect to recruitment mechanism and proper uneterstanding of the dynamics leading to sustainance of fish populations. It should be the central theme of the fisheries biologist and managers to extract the bilogical information relevant to the proper understanding of this part of the population. A number of studies in the Mwanza gulf and Lake Victoria have emphasized the need to monitor the fishery by conducting observations of stock size, migration, catch effort data and growth of big specimen (Acere 1981, Goudsward et al 1984, Asila. Ogari 1988 and Okemwa 1984). The present paper discusses the preliminary information on the size structure, mortality and migration of juvenile Nile perch. The long term objectives of the programme is aimed at describing the size structure, growth, mortality, recruitment pattern and population dynamics of the Nile perch up to 30 cm total length in the, Mwanza Gulf.
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The off-cycle refrigerant mass migration has a direct influence on the on-cycle performance since compressor energy is necessary to redistribute the refrigerant mass. No studies, as of today, are available in the open literature which experimentally measured the lubricant migration within a refrigeration system during cycling or stop/start transients. Therefore, experimental procedures measuring the refrigerant and lubricant migration through the major components of a refrigeration system during stop/start transients were developed and implemented. Results identifying the underlying physics are presented. The refrigerant and lubricant migration of an R134a automotive A/C system-utilizing a fixed orifice tube, minichannel condenser, plate and fin evaporator, U-tube type accumulator and fixed displacement compressor-was measured across five sections divided by ball valves. Using the Quick-Closing Valve Technique (QCVT) combined with the Remove and Weigh Technique (RWT) using liquid nitrogen as the condensing agent resulted in a measurement uncertainty of 0.4 percent regarding the total refrigerant mass in the system. The determination of the lubricant mass distribution was achieved by employing three different techniques-Remove and Weigh, Mix and Sample, and Flushing. To employ the Mix and Sample Technique a device-called the Mix and Sample Device-was built. A method to separate the refrigerant and lubricant was developed with an accuracy-after separation-of 0.04 grams of refrigerant left in the lubricant. When applying the three techniques, the total amount of lubricant mass in the system was determined to within two percent. The combination of measurement results-infrared photography and high speed and real time videography-provide unprecedented insight into the mechanisms of refrigerant and lubricant migration during stop-start operation. During the compressor stop period, the primary refrigerant mass migration is caused by, and follows, the diminishing pressure difference across the expansion device. The secondary refrigerant migration is caused by a pressure gradient as a result of thermal nonequilibrium within the system and causes only vapor phase refrigerant migration. Lubricant migration is proportional to the refrigerant mass during the primary refrigerant mass migration. During the secondary refrigerant mass migration lubricant is not migrating. The start-up refrigerant mass migration is caused by an imbalance of the refrigerant mass flow rates across the compressor and expansion device. The higher compressor refrigerant mass flow rate was a result of the entrainment of foam into the U-tube of the accumulator. The lubricant mass migration during the start-up was not proportional to the refrigerant mass migration. The presence of water condensate on the evaporator affected the refrigerant mass migration during the compressor stop period. Caused by an evaporative cooling effect the evaporator held 56 percent of the total refrigerant mass in the system after three minutes of compressor stop time-compared to 25 percent when no water condensate was present on the evaporator coil. Foam entrainment led to a faster lubricant and refrigerant mass migration out of the accumulator than liquid entrainment through the hole at the bottom of the U-tube. The latter was observed for when water condensate was present on the evaporator coil because-as a result of the higher amount of refrigerant mass in the evaporator before start-up-the entrainment of foam into the U-tube of the accumulator ceased before the steady state refrigerant mass distribution was reached.
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Negative-ion mode electrospray ionization, ESI(-), with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) was coupled to a Partial Least Squares (PLS) regression and variable selection methods to estimate the total acid number (TAN) of Brazilian crude oil samples. Generally, ESI(-)-FT-ICR mass spectra present a power of resolution of ca. 500,000 and a mass accuracy less than 1 ppm, producing a data matrix containing over 5700 variables per sample. These variables correspond to heteroatom-containing species detected as deprotonated molecules, [M - H](-) ions, which are identified primarily as naphthenic acids, phenols and carbazole analog species. The TAN values for all samples ranged from 0.06 to 3.61 mg of KOH g(-1). To facilitate the spectral interpretation, three methods of variable selection were studied: variable importance in the projection (VIP), interval partial least squares (iPLS) and elimination of uninformative variables (UVE). The UVE method seems to be more appropriate for selecting important variables, reducing the dimension of the variables to 183 and producing a root mean square error of prediction of 0.32 mg of KOH g(-1). By reducing the size of the data, it was possible to relate the selected variables with their corresponding molecular formulas, thus identifying the main chemical species responsible for the TAN values.
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The essential oil from the leaves of Ocimum kilimandscharicum (EOOK), collected in Dourados-MS, was investigated for anticancer, anti-inflammatory and antioxidant activity and chemical composition. The essential oil was extracted by hydrodistillation, and the chemical composition was performed by gas chromatography-mass spectrometry. The essential oil was evaluated for free radical-scavenging activity using the DPPH assay and was tested in an anticancer assay against ten human cancer cell lines. The response parameter (GI50) was calculated for the cell lines tested. The anti-inflammatory activity was evaluated using carrageenan-induced pleurisy in mice. The chemical composition showed 45 components with a predominance of monoterpenes, such as camphor (51.81%), 1,8 cineole (20.13%) and limonene (11.23%). The EOOK exhibited potent free radical-scavenging activity by the DPPH assay with a GI50 of 8.31 μg/ml. The major constituents, pure camphor (IC50=12.56 μg/ml) and mixture of the limonene: 1, 8 cineole (IC50=23.25 μg/ml) displayed a potent activity. The oral administration of EOOK (at 30 and 100 mg kg(-1)), as well as the pure camphor or a mixture of 1,8 cineole with limonene, significantly inhibited the carrageenan (Cg) induced pleurisy, reducing the migration of total leukocytes in mice by 82 ± 4% (30 mg kg(-1) of EOOK), 95 ± 4% (100 mg kg(-1) of EOOK), 83 ± 9% (camphor) and 80 ± 5% (mixture of 1,8 cineole:limonene 1:1). In vitro cytotoxicity screening against a human ovarian cancer cell line displayed high selectivity and potent anticancer activity with GI50=31.90 mg ml(-1). This work describes the anti-inflammatory, anticancer and antioxidant effects of EOOK for the first time. The essential oil exhibited marked anti-inflammatory, antioxidant and anticancer effects, an effect that can be attributed the presence of majorital compounds, and the response profiles from chemical composition differed from other oils collected in different locales.
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ANKHD1 is highly expressed in human acute leukemia cells and potentially regulates multiple cellular functions through its ankyrin-repeat domains. In order to identify interaction partners of the ANKHD1 protein and its role in leukemia cells, we performed a yeast two-hybrid system screen and identified SIVA, a cellular protein known to be involved in proapoptotic signaling pathways. The interaction between ANKHD1 and SIVA was confirmed by co-imunoprecipitation assays. Using human leukemia cell models and lentivirus-mediated shRNA approaches, we showed that ANKHD1 and SIVA proteins have opposing effects. While it is known that SIVA silencing promotes Stathmin 1 activation, increased cell migration and xenograft tumor growth, we showed that ANKHD1 silencing leads to Stathmin 1 inactivation, reduced cell migration and xenograft tumor growth, likely through the inhibition of SIVA/Stathmin 1 association. In addition, we observed that ANKHD1 knockdown decreases cell proliferation, without modulating apoptosis of leukemia cells, while SIVA has a proapoptotic function in U937 cells, but does not modulate proliferation in vitro. Results indicate that ANKHD1 binds to SIVA and has an important role in inducing leukemia cell proliferation and migration via the Stathmin 1 pathway. ANKHD1 may be an oncogene and participate in the leukemia cell phenotype.
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Primary X-ray spectra were measured in the range of 80-150kV in order to validate a computer program based on a semiempirical model. The ratio between the characteristic and total air Kerma was considered to compare computed results and experimental data. Results show that the experimental spectra have higher first HVL and mean energy than the calculated ones. The ratios between the characteristic and total air Kerma for calculated spectra are in good agreement with experimental results for all filtrations used.
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A stereoselective total synthesis of (-)-cryptocaryol A () is described. Key features of the 17-step route include the use of three boron-mediated aldol reaction-reduction sequences to control all stereocenters and an Ando modification of the Horner-Wadsworth-Emmons olefination that permitted the installation of the Z double bond of the α-pyrone ring.
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In this work a fast method for the determination of the total sugar levels in samples of raw coffee was developed using the near infrared spectroscopy technique and multivariate regression. The sugar levels were initially obtained using gravimety as the reference method. Later on, the regression models were built from the near infrared spectra of the coffee samples. The original spectra were pre-treated according to the Kubelka-Munk transformation and multiplicative signal correction. The proposed analytical method made possible the direct determination of the total sugar levels in the samples with an error lower by 8% with respect to the conventional methodology.
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The purpose of this study was to evaluate the dentin shear bond strength of four adhesive systems (Adper Single Bond 2, Adper Prompt L-Pop, Magic Bond DE and Self Etch Bond) in regards to buccal and lingual surfaces and dentin depth. Forty extracted third molars had roots removed and crowns bisected in the mesiodistal direction. The buccal and lingual surfaces were fixed in a PVC/acrylic resin ring and were divided into buccal and lingual groups assigned to each selected adhesive. The same specimens prepared for the evaluation of superficial dentin shear resistance were used to evaluate the different depths of dentin. The specimens were identified and abraded at depths of 0.5, 1.0, 1.5 and 2.0 mm. Each depth was evaluated by ISO TR 11405 using an EMIC-2000 machine regulated at 0.5 mm/min with a 200 Kgf load cell. We performed statistical analyses on the results (ANOVA, Tukey and Scheffé tests). Data revealed statistical differences (p < 0.01) in the adhesive and depth variation as well as adhesive/depth interactions. The Adper Single Bond 2 demonstrated the highest mean values of shear bond strength. The Prompt L-Pop product, a self-etching adhesive, revealed higher mean values compared with Magic Bond DE and Self Etch Bond adhesives, a total and self-etching adhesive respectively. It may be concluded that the shear bond strength of dentin is dependent on material (adhesive system), substrate depth and adhesive/depth interaction.
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OBJETIVOS: avaliar e mensurar a sutura palatina mediana por meio de radiografias oclusais totais de maxila digitalizadas, antes e depois da sua disjunção. MÉTODOS: a amostra constou de 17 pacientes, com idades entre 7 e 22 anos. Radiografias oclusais totais da maxila foram executadas antes e depois da abertura da sutura palatina mediana, e digitalizadas em scanner HP Scanjet 6110 C com adaptador de transparências HPC 6261 6100 C, utilizando-se o programa Deskscan II. Para a avaliação e medição, foi utilizado o programa Radioimp® (Radiomemory, MG/Brasil). Na análise estatística, foram utilizados a média, o desvio-padrão, o coeficiente de variação e os testes "t" e ANOVA. CONCLUSÕES: após os resultados, foi possível concluir que (1) na região dos incisivos, houve uma abertura palatina mediana estatisticamente significativa; (2) houve abertura de diastema entre os incisivos centrais superiores em torno de 69,37% dos casos; (3) houve uma maior abertura da sutura palatina mediana na região a 10mm a partir da crista para posterior, em comparação com a região a 3mm para posterior do parafuso expansor; (4) na região a 3mm para posterior do parafuso expansor houve uma abertura de 35,97%, e na região a 10mm para posterior da crista uma abertura de 69,37%.
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The aim of this study was to estimate the additional cost of treatment of a group of nosocomial infections in a tertiary public hospital. A retrospective observational cohort study was conducted by means of analyzing the medical records of 34 patients with infection after total knee arthroplasty, diagnosed in 2006 and 2007, who met the criteria for nosocomial infection according to the Centers for Disease Control and Prevention. To estimate the direct costs of treatment for these patients, the following data were gathered: length of hospital stay, laboratory tests, imaging examinations, and surgical procedures performed. Their costs were estimated from the minimum values according to the Brazilian Medical Association. The estimated cost of the antibiotics used was also obtained. The total length of stay in the ward was 976 days, at a cost of US$ 18,994.63, and, in the intensive care unit, it was 34 days at a cost of US$ 5,031.37. Forty-two debridement procedures were performed, at a cost of US$ 5,798.06, and 1965 tests (laboratory and imaging) were also performed, at a cost of US$ 15,359.25. US$ 20,845.01 was spent on antibiotics and US$ 1,735.16 on vacuum assisted closure therapy, microsurgical flaps, implant removal, spacer use, and surgical revision. The total additional cost of these cases of hospital infection in 2006 and 2007 was of US$ 91,843.75. Based on that, we demonstrate that the high cost of treatment for hospital infections emphasizes the importance of taking measures to prevent and control hospital infection.
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The present paper reports results of the effect of Potato virus X (PVX) on the contents of total phenols and alkaloids in leaves of Datura stramonium. A significant decrease in the contents of phenols and alkaloids was observed in leaves inoculated with PVX (X-I). However, there was an increase in the percentage of phenols in leaves rubbed with phosphate buffer (C1-I) and in leaves from the nodes immediately above, possibly induced by mechanical injury. Gas chromatography/mass spectroscopy revealed amounts of scopolamine in samples submitted to all treatments, except X-I, in which the amount of this alkaloid was low. High amounts of an unidentified compound (molecular ion m/z 302 and a prominent peak at m/z 129) were noted in extracts from leaves X-I, C1-I and leaves from the nodes immediately above the leaves inoculated with PVX. It is suggested that the synthesis and accumulation of the unidentified compound is a result of stress from mechanical injury and virus inoculation.