1000 resultados para Lucianus, of Samosata
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.
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Mode of access: Internet.
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O trabalho aborda a micronarrativa do Homem rico e do pobre Lázaro de Lc. 16. 19-31. As relações entre os dois personagens da narrativa se mostram invertidas, sugerindo um tom irônico por parte do narrador lucano. A inversão os coloca no mesmo lugar, o Hades, mas em posições diferentes, gerando um conflito na narrativa. Buscou-se observar o motivo da inversão, seu papel na cena e seu impacto na trama da narrativa e em seus leitores. Examinou-se na sequência narrativa da parábola a relação entre seu enredo unificante e seu enredo episódico buscando o motivo dela dentro dessa sequência, o que demonstrou ser uma narrativa direcionada aos fariseus, onde sugerimos ter um tom irônico em uma crítica social. Buscou-se retratar o imaginário desse lugar de inversão, trazendo algumas imagens do imaginário judaico e greco-romano a partir de algumas fontes literárias, principalmente a obra Diálogo dos Mortos, de Luciano de Samósata do II séc. Demonstrou-se haver uma intertextualidade, onde ecos do relato lucano são vistos na obra de Luciano. Para tal elaboração, os passos da narratologia evidenciaram o que se pretendeu analisar.
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In Charon or the Inspectors we find the ferryman of the underworld on earth, talking to the god Hermes about wealth, happiness, and the vain human striving for material goods. The piece has been considered to be an example of Menippean satire inside the corpus of Lucian"s works. Homeric poetry is always in the background. Lucian uses Homeric verses, or rather, verses structured in the Homeric manner, to formulate his critical view of the mortal world; in addition, he puts these verses into the mouth of a character who must temporarily give up his job as a ferryman in order to practise the art of rhapsody. This paper analyses a textual problem: the two variants in Cont. 7 referring to Homer in the manuscript tradition. In a context in which Lucian wants to make fun not just of foolish humans but also of the Greek poet par excellence, the reading of the ueteres seems more appropriate because it illustrates better Lucian"s parodic intention in recalling Homer and in trying to adapt form and content to the Greek tradition.
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In Lucian Scythian (§11), all previous editors have corrected the word ¢p£xetai as it appears in the manuscripts to p£xetai. We aim to justify the restoration of the original text because, obviously, it is possible in terms of form, and, besides, it seems more appropriate to the context. The verb ¢p£gomai implies the notion of being moved from one place to another, while p£gomai expresses only the notion of simple attraction which does not involve actual movement. This notion of true surrendering through the senses seems to match the idea developed here by Lucian; loci paralleli in Lucian himself and other Attic authors help us to confirm this interpretation.
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En Menipo o Necromancia, el encuentro entre el filósofos cínico Menipo de Gádara y su interlocutor sirve como marco para que este relate su peripecia infernal. En la obra no se especifica dónde tiene lugar dicho encuentro; no obstante, pensamos que el samosatense incluye un sutil juego literario mediante el cual el auditorio podría identificar el escenario de dicho encuentro con la polis beocia de Tebas.
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Characterized for the first time in erythrocytes, phosphatidylinositol phosphate kinases (PIP kinases) belong to a family of enzymes that generate various lipid messengers and participate in several cellular processes, including gene expression regulation. Recently, the PIPKIIα gene was found to be differentially expressed in reticulocytes from two siblings with hemoglobin H disease, suggesting a possible relationship between PIPKIIα and the production of globins. Here, we investigated PIPKIIα gene and protein expression and protein localization in hematopoietic-derived cells during their differentiation, and the effects of PIPKIIα silencing on K562 cells. PIPKIIα silencing resulted in an increase in α and γ globins and a decrease in the proliferation of K562 cells without affecting cell cycle progression and apoptosis. In conclusion, using a cell line model, we showed that PIPKIIα is widely expressed in hematopoietic-derived cells, is localized in their cytoplasm and nucleus, and is upregulated during erythroid differentiation. We also showed that PIPKIIα silencing can induce α and γ globin expression and decrease cell proliferation in K562 cells.
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The cerebellum is an important site for cortical demyelination in multiple sclerosis, but the functional significance of this finding is not fully understood. To evaluate the clinical and cognitive impact of cerebellar grey-matter pathology in multiple sclerosis patients. Forty-two relapsing-remitting multiple sclerosis patients and 30 controls underwent clinical assessment including the Multiple Sclerosis Functional Composite, Expanded Disability Status Scale (EDSS) and cerebellar functional system (FS) score, and cognitive evaluation, including the Paced Auditory Serial Addition Test (PASAT) and the Symbol-Digit Modalities Test (SDMT). Magnetic resonance imaging was performed with a 3T scanner and variables of interest were: brain white-matter and cortical lesion load, cerebellar intracortical and leukocortical lesion volumes, and brain cortical and cerebellar white-matter and grey-matter volumes. After multivariate analysis high burden of cerebellar intracortical lesions was the only predictor for the EDSS (p<0.001), cerebellar FS (p = 0.002), arm function (p = 0.049), and for leg function (p<0.001). Patients with high burden of cerebellar leukocortical lesions had lower PASAT scores (p = 0.013), while patients with greater volumes of cerebellar intracortical lesions had worse SDMT scores (p = 0.015). Cerebellar grey-matter pathology is widely present and contributes to clinical dysfunction in relapsing-remitting multiple sclerosis patients, independently of brain grey-matter damage.
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To detect the presence of male DNA in vaginal samples collected from survivors of sexual violence and stored on filter paper. A pilot study was conducted to evaluate 10 vaginal samples spotted on sterile filter paper: 6 collected at random in April 2009 and 4 in October 2010. Time between sexual assault and sample collection was 4-48hours. After drying at room temperature, the samples were placed in a sterile envelope and stored for 2-3years until processing. DNA extraction was confirmed by polymerase chain reaction for human β-globin, and the presence of prostate-specific antigen (PSA) was quantified. The presence of the Y chromosome was detected using primers for sequences in the TSPY (Y7/Y8 and DYS14) and SRY genes. β-Globin was detected in all 10 samples, while 2 samples were positive for PSA. Half of the samples amplified the Y7/Y8 and DYS14 sequences of the TSPY gene and 30% amplified the SRY gene sequence of the Y chromosome. Four male samples and 1 female sample served as controls. Filter-paper spots stored for periods of up to 3years proved adequate for preserving genetic material from vaginal samples collected following sexual violence.