Notch signaling in the brain: in good and bad times.

Notch signaling is an evolutionarily conserved pathway, which is fundamental for neuronal development and specification. In the last decade, increasing evidence has pointed out an important role of this pathway beyond embryonic development, indicating that Notch also displays a critical function in the mature brain of vertebrates and invertebrates. This pathway appears to be involved in neural progenitor regulation, neuronal connectivity, synaptic plasticity and learning/memory. In addition, Notch appears to be aberrantly regulated in neurodegenerative diseases, including Alzheimer's disease and ischemic injury. The molecular mechanisms by which Notch displays these functions in the mature brain are not fully understood, but are currently the subject of intense research. In this review, we will discuss old and novel Notch targets and molecular mediators that contribute to Notch function in the mature brain and will summarize recent findings that explore the two facets of Notch signaling in brain physiology and pathology.

Good and bad practices in pv plants

The PVCROPS project (PhotoVolta ic Cost r€duction, Reliability, Operational performance, Prediction and Simulation), cofinanced by European Commission in the frame of Seventh Framework Programme, has compiled in the “Good and bad practices: Manual to improve the quality and reduce the cost of PV systems” a collection of good and bad practices in actual PV plants . All the situations it collects represent the state-of-the-art of existing PV installations all around Europe. They show how the different parts of an installation can be implem ented properly or not. The aim of this manual is to represent a reference text which can help any PV actor (installers, electricians, maintenance operators, owners, etc.) not only to check and improve an already existing installation but will also, and mainly, avoid the previously known bad practices for the construction of a new PV installation. Thus, solving a priori the known errors, new PV installations will be more reliable, efficient and cost-effective and can recover the initial investment in a shorter time. The manual is going to be free available in the PVCROPS website in several languages.

A good and a bad government,

Mode of access: Internet.

Richard Edney and the governor's family. A rusurban tale ... of morals, sentiment, and life ... containing, also hints on being good and doing good.

Mode of access: Internet.

The works of Francis Bacon, baron of Verulam, viscount St. Alban, and lord high chancellor of England.

Instaurationis magnae, pars V. Opuscula philosophica. Descriptio globi intellectualis. Opera civilia et moralia. Historia regni Henri Septimi.--v.10 Sermones fideles, sive Interiora rerum. De sapientia veterum. Meditationes sacrae. Epistolae. Index rerum in v. 7, 8, 8, et 10. Index to English part, comprised in the six first volumes.

An inquiry into the original of our ideas of beauty and virtue.

I. Concerning beauty, order, harmony, design.--II. Concerning moral good and evil.

A view of the human heart : in a series of allegorical designs illustrative of its evil passions ; for the instruction of youth ; together with The issues of life ; for the consideration of those who have erred from the way of truth /

Mode of access: Internet.

Cheering views of man and Providence,

Mode of access: Internet.

A poetical essay on the first good and the first fair : with salutatory addresses /

Mode of access: Internet.

New method, which teaches how to make vegetable manure, by a course of high fermentation, in fifteen days, without cattle, as good and more durable than farm manure: to appropriate it to the nature of soils and families of plants, and with great economy: it further shows how to prepare vegetable and mineral composts, and contains various processes.

Microfilm. Ann Arbor, Mich., Xerox University Microfilms, 1974. 1 reel. 35 mm. (American Culture Series, reel 617.3)

A treatise of all sorts of foods, both animal and vegetable: also of drinkables: giving an account how to chuse the best sort of all kinds; of the good and bad effects they produce; the principles they abound with; the time, age, and constitution they are adapted to. Wherin their nature and use is explain'd according to the sentiments of the most eminent physicians and naturalists, antient and modern ...

Mode of access: Internet.

Philosophy and psychology pamphlets

A collection of miscellaneous pamphlets.

Philosophy and psychology pamphlets

A collection of miscellaneous pamphlets.

The devils and evil spirits of Babylonia,

Mode of access: Internet.

Manners good and bad : at home and in society /

Mode of access: Internet.