Buccodental health and oral mucositis. Clinical study in patients with hematological diseases

Objectives: The objective of the present study is to assess whether a good buccodental status (evaluated by means of dentogingival indices), is associated with a lower incidence and severity of oral mucositis in patients with hematological diseases who receive treatment with chemotherapy or bone marrow transplant. Study design: The study was carried out on 97 patients admitted to the Hematology Service of the Hospital Duran y Reynals in Barcelona during 2002-2003. These patients received treatment with chemotherapy or conditioning prior to bone marrow transplant. A descriptive study was made, analyzing oral hygiene, one dental index, and two gingivales indices, and evaluating their relationship with the appearance of mucositis. Results: The patients with high plaque (PI) and gingival (GI) indices during chemotherapy presented a higher percentage of mucositis (77.4% and 65.7% respectively) against those who had little or no visible plaque. In the case of the PI, the differences were statistically significant (p=0.015). Likewise, patients who brushed their teeth 3 times/day presented mucositis in only 26.7% of cases, against those who did not brush, or brushed only once a day (65.9% and 68.4%), these differences also being statistically significant (p=0.013). The CAO showed similar results in patients with or without mucositis (7.59 and 7.03 respectively). Conclusions: In our study, a good gingival status as well as good oral hygiene during chemoradiotherapy is associated with a lower incidence and severity of mucositis.

Executive functions profile in extreme eating/weight conditions: from anorexia nervosa to obesity

Extreme weight conditions (EWC) groups along a continuum may share some biological risk factors and intermediate neurocognitive phenotypes. A core cognitive trait in EWC appears to be executive dysfunction, with a focus on decision making, response inhibition and cognitive flexibility. Differences between individuals in these areas are likely to contribute to the differences in vulnerability to EWC. The aim of the study was to investigate whether there is a common pattern of executive dysfunction in EWC while comparing anorexia nervosa patients (AN), obese subjects (OB) and healthy eating/weight controls (HC).

Allelic diversity and population structure in Vibrio cholerae O139 Bengal based on nucleotide sequence analysis

Comparative analysis of gene fragments of six housekeeping loci, distributed around the two chromosomes of Vibrio cholerae, has been carried out for a collection of 29 V. cholerae O139 Bengal strains isolated from India during the first epidemic period (1992 to 1993). A toxigenic O1 ElTor strain from the seventh pandemic and an environmental non-O1/non-O139 strain were also included in this study. All loci studied were polymorphic, with a small number of polymorphic sites in the sequenced fragments. The genetic diversity determined for our O139 population is concordant with a previous multilocus enzyme electrophoresis study in which we analyzed the same V. cholerae O139 strains. In both studies we have found a higher genetic diversity than reported previously in other molecular studies. The results of the present work showed that O139 strains clustered in several lineages of the dendrogram generated from the matrix of allelic mismatches between the different genotypes, a finding which does not support the hypothesis previously reported that the O139 serogroup is a unique clone. The statistical analysis performed in the V. cholerae O139 isolates suggested a clonal population structure. Moreover, the application of the Sawyer's test and split decomposition to detect intragenic recombination in the sequenced gene fragments did not indicate the existence of recombination in our O139 population.

Molecular phylogenetics and temporal diversification in the genus Aeromonas based on the sequences of five housekeeping genes

Several approaches have been developed to estimate both the relative and absolute rates of speciation and extinction within clades based on molecular phylogenetic reconstructions of evolutionary relationships, according to an underlying model of diversification. However, the macroevolutionary models established for eukaryotes have scarcely been used with prokaryotes. We have investigated the rate and pattern of cladogenesis in the genus Aeromonas (γ-Proteobacteria, Proteobacteria, Bacteria) using the sequences of five housekeeping genes and an uncorrelated relaxed-clock approach. To our knowledge, until now this analysis has never been applied to all the species described in a bacterial genus and thus opens up the possibility of establishing models of speciation from sequence data commonly used in phylogenetic studies of prokaryotes. Our results suggest that the genus Aeromonas began to diverge between 248 and 266 million years ago, exhibiting a constant divergence rate through the Phanerozoic, which could be described as a pure birth process.

Draft genome sequence of Aeromonas molluscorum strain 848TT, isolated from bivalve molluscs

We report here the draft genome sequence of Aeromonas molluscorum 848T, the type strain of this Aeromonas species, which was isolated from wedge shells (Donax trunculus) obtained from a retail market in Barcelona, Spain, in 1997.

Divergent evolution and purifying selection of the flaA gene sequences in Aeromonas

BACKGROUND: The bacterial flagellum is the most important organelle of motility in bacteria and plays a key role in many bacterial lifestyles, including virulence. The flagellum also provides a paradigm of how hierarchical gene regulation, intricate protein-protein interactions and controlled protein secretion can result in the assembly of a complex multi-protein structure tightly orchestrated in time and space. As if to stress its importance, plants and animals produce receptors specifically dedicated to the recognition of flagella. Aside from motility, the flagellum also moonlights as an adhesion and has been adapted by humans as a tool for peptide display. Flagellar sequence variation constitutes a marker with widespread potential uses for studies of population genetics and phylogeny of bacterial species. RESULTS: We sequenced the complete flagellin gene (flaA) in 18 different species and subspecies of Aeromonas. Sequences ranged in size from 870 (A. allosaccharophila) to 921 nucleotides (A. popoffii). The multiple alignment displayed 924 sites, 66 of which presented alignment gaps. The phylogenetic tree revealed the existence of two groups of species exhibiting different FlaA flagellins (FlaA1 and FlaA2). Maximum likelihood models of codon substitution were used to analyze flaA sequences. Likelihood ratio tests suggested a low variation in selective pressure among lineages, with an omega ratio of less than 1 indicating the presence of purifying selection in almost all cases. Only one site under potential diversifying selection was identified (isoleucine in position 179). However, 17 amino acid positions were inferred as sites that are likely to be under positive selection using the branch-site model. Ancestral reconstruction revealed that these 17 amino acids were among the amino acid changes detected in the ancestral sequence. CONCLUSION: The models applied to our set of sequences allowed us to determine the possible evolutionary pathway followed by the flaA gene in Aeromonas, suggesting that this gene have probably been evolving independently in the two groups of Aeromonas species since the divergence of a distant common ancestor after one or several episodes of positive selection. REVIEWERS: This article was reviewed by Alexey Kondrashov, John Logsdon and Olivier Tenaillon (nominated by Laurence D Hurst).

Draft genome sequence of the Aeromonas diversa type strain

We present here the first genome sequence of the Aeromonas diversa type strain (CECT 4254T). This strain was isolated from the leg wound of a patient in New Orleans (Louisiana, USA) and was originally described as Enteric Group 501 and distinguished from A. schubertii by DNADNA hybridization and phenotypical characterization.

Resolución N° 33 de 7 de Marzo de 2007 ¿Cuáles son los elementos que evalúa la Cámara de Comercio en los nombramientos de junta directiva?

Servicios registrales

Identificación y análisis de las enfermedades más comúnes que sepresentan en los empleados de atención al público (cajeros), en algunas sucursales bancarias de Monterrey, N.L. y su relación con factores de riesgo de trabajo que ahí existen

Tesis (Maestría en Salud Pública con Especialidad en Salud en el Trabajo) UANL

Identificación de riesgos en plantas de polietileno de baja densidad

Tresis ( Maestro en Ciencias de la Administración con Especialidad en Producción y Calidad ) - U.A.N.L, 2003

Defensa, jurídica alegación y manifestación con que en derecho, justicia, y razón satisface, D. Andrés Alvarez Montero Prieto de Bonilla, a la demanda y pleito que se le ha puesto

UANL

Rutas biológicas virtuales por Puerto Real.

Se presenta memoria final de proyecto educativo que trata de acercar al alumnado del centro, y por extensión de toda la localidad y la comarca, a una realidad en la que ya vienen trabajando en los diez últimos cursos: la educación medioambiental. Se pretende aprovechar la experiencia y el gran trabajo realizado cursos pasados para editarlos en soportes relacionados con las nuevas tecnologías. Se realiza en el CEIP El Trocadero de Puerto Real, Cádiz y se trata de diseñar una serie de itinerarios ecológicos por las zonas verdes y espacios naturales de la zona de Puerto Real. Los objetivos son: respeto por la naturaleza y del entorno más cercano gracias a su conocimiento; aprendizaje de técnicas de observación directa del entorno inmediato; utilización de las TICs para alumnado y profesorado. El proceso consta de varias fases: visita de itinerarios para la elección de los posibles recursos; elaboración de soportes tanto fotográficos como video; realización de reuniones periódicas para trabajar boceto de presentación; visionado de los diferentes soportes que permanecían en el centro; dar cuerpo a la primera ruta. Los resultados han sido: elaboración y digitalización de todas las fichas de plantas propuestas; se han elaborado, limpiado, seleccionado y digitalizado las distintas láminas y dibujos de animales y plantas de la zona; se confeccionan los distintos planos y rutas a desarrollar para luego digitalizarlos; se recopilaron, clasificaron y ordenaron las distintas imágenes obtenidas en salidas y en material específico del centro; todos los temas tratados se han informatizado.

Normativa del sistema universitario de la Región de Murcia.

Compilación normativa vigente en materias universitarias para la Región de Murcia que forman el marco jurídico completo para el desarrollo de estas enseñanzas, constituyendo un instrumento de consulta para todos aquellos que integran la comunidad universitaria de la Región.

Normativa del Sistema Universitario de la Región de Murcia.

Recopilación de la normativa existente en materia universitaria en la Región de Murcia como testigo de los cambios sufridos en el sistema universitario regional. Se presenta como el resultado obtenido ante la necesidad de ofrecer un corpus normativo que permita legislar según las competencias atribuidas a la Región, en materia de universidades, haciendo referencia a su creación, organización, coordinación, ordenación, acceso universitario, personal docente e investigador y precios públicos..

Itinerarios educativos del Principado de Asturias 2003.

Resumen basado en la publicación