859 resultados para Design for flexibility in use
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Es un recurso para los profesores de secundaria que trata cada una de las principales áreas de especialización, es decir, tecnología electrónica y de comunicaciones, tecnología de los alimentos, tecnología de los materiales y tecnología textil. También, incluye temas como el diseño y la tecnología en el plan de estudios, el uso de las tecnologías de la información y la comunicación (TIC) en su enseñanza, la importancia de la salud y la seguridad, y la integración de la alfabetización, la aritmética, la ciudadanía y la sostenibilidad en el diseño y tecnología. Además abarca otras cuestiones: planificación de las clases, evaluación del aprendizaje, gestión del aula y desarrollo profesional.
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Recurso para estudiantes con nivel medio o avanzado en inglés que cuenta con cuarenta unidades en la tecnología de las comunicaciones de información. Incluye sistemas informáticos, procesamiento de textos, hojas de cálculo y bases de datos, aplicaciones multimedia, correo electrónico, diseño web y seguridad de Internet, también tiene temas referentes a los teléfonos móviles y a la video conferencia. Hay unidades que explican la formación de palabras y funciones del lenguaje característico utilizado en el mundo de las TIC y como utilizarlo. Diseñado principalmente como una referencia de autoaprendizaje y libro de prácticas, también puede utilizarse para complementar el trabajo de aula.
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Libro orientado al auto-estudio para alumnos de nivel intermedio de inglés. Está estructurado en ciento cuarenta y cinco lecciones, cada una sobre un tema determinado de gramática inglesa, con su explicación y ejemplos en la página izquierda y ejercicios para practicar en la página derecha. Al final del libro hay una sección con las soluciones, siete apéndices sobre verbos regulares e irregulares, formas verbales para el presente y pasado, formas verbales para el futuro, verbos modales, contracciones, ortografía e inglés americano, un apartado con ejercicios adicionales que concentran varios temas de gramática en un mismo ejercicio, y una guía de estudio para ayudar a decidir qué temas repasar. Incluye un cd-rom con más ejercicios y mil setecientas preguntas de examen.
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Resumen basado en el de la publicación. Resumen y título en castellano y en inglés
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Resumen tomado de la publicaci??n
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This paper discusses concepts of value from the point of view of the user of the space and the counter view of the provider of the same. Land and property are factors of production. The value of the land flows from the use to which it is put, and that in turn, is dependent upon the demand (and supply) for the product or service that is produced/provided from that space. If there is a high demand for the product (at a fixed level of supply), the price will increase and the economic rent for the land/property will increase accordingly. This is the underlying paradigm of Ricardian rent theory where the supply of land is fixed and a single good is produced. In such a case the rent of land is wholly an economic rent. Economic theory generally distinguishes between two kinds of price, price of production or “value in use” (as determined by the labour theory of value), and market price or “value in exchange” (as determined by supply and demand). It is based on a coherent and consistent theory of value and price. Effectively the distinction is between what space is ‘worth’ to an individual and that space’s price of exchange in the market place. In a perfect market where any individual has access to the same information as all others in the market, price and worth should coincide. However in a market where access to information is not uniform, and where different uses compete for the same space, it is more likely that the two figures will diverge. This paper argues that the traditional reliance of valuers to use methods of comparison to determine “price” has led to an artificial divergence of “value in use” and “value in exchange”, but now such comparison are becoming more difficult due to the diversity of lettings in the market place, there will be a requirement to return to fundamentals and pay heed to the thought process of the user in assessing the worth of the space to be let.
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Psoriasis is a common, chronic and relapsing inflammatory skin disease. It affects approximately 2% of the western population and has no cure. Combination therapy for psoriasis often proves more efficacious and better tolerated than monotherapy with a single drug. Combination therapy could be administered in the form of a co-drug, where two or more therapeutic compounds active against the same condition are linked by a cleavable covalent bond. Similar to the pro-drug approach, the liberation of parent moieties post-administration, by enzymatic and/or chemical mechanisms, is a pre-requisite for effective treatment. In this study, a series of co-drugs incorporating dithranol in combination with one of several non-steroidal anti-inflammatory drugs, both useful for the treatment of psoriasis, were designed, synthesized and evaluated. An ester co-drug comprising dithranol and naproxen in a 1:1 stoichiometric ratio was determined to possess the optimal physicochemical properties for topical delivery. The co-drug was fully hydrolyzed in vitro by porcine liver esterase within four hours. When incubated with homogenized porcine skin, 9.5% of the parent compounds were liberated after 24 h, suggesting in situ esterase-mediated cleavage of the co-drug would occur within the skin. The kinetics of the reaction revealed first order kinetics, Vmax = 10.3 μM/min and Km = 65.1 μM. The co-drug contains a modified dithranol chromophore that was just 37% of the absorbance of dithranol at 375 nm and suggests reduced skin/clothes staining. Overall, these findings suggest that the dithranol-naproxen co-drug offers an attractive, novel approach for the treatment of psoriasis.
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Thermal generation is a vital component of mature and reliable electricity markets. As the share of renewable electricity in such markets grows, so too do the challenges associated with its variability. Proposed solutions to these challenges typically focus on alternatives to primary generation, such as energy storage, demand side management, or increased interconnection. Less attention is given to the demands placed on conventional thermal generation or its potential for increased flexibility. However, for the foreseeable future, conventional plants will have to operate alongside new renewables and have an essential role in accommodating increasing supply-side variability. This paper explores the role that conventional generation has to play in managing variability through the sub-system case study of Northern Ireland, identifying the significance of specific plant characteristics for reliable system operation. Particular attention is given to the challenges of wind ramping and the need to avoid excessive wind curtailment. Potential for conflict is identified with the role for conventional plant in addressing these two challenges. Market specific strategies for using the existing fleet of generation to reduce the impact of renewable resource variability are proposed, and wider lessons from the approach taken are identified.
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This article investigates student behaviour on collaborative assignments, looking at the relationship between task type and interaction, and considers the implications for task design. Students reported on interactions in a year-long workplace-focussed group communication project, comparing these with interactions on other academy based group assignments. Differences were seen in the amount of brainstorming, the criteria for dividing up work, the intensity of editing, and how conflict was managed. Contributing factors to these differences included the presence or absence of a creative element, the instrumental nature of the task, and the need for a collective approach inherent in the task design.