Radar Rio+20: a pauta e o caráter da Rio+20

Trecho de conversa com jornalistas realizada como parte do projeto Radar Rio+20, uma parceria GVces, ISA e Vitae Civilis

O Caráter Tectônico do Moderno Brasileiro: Bernardes e Campello na Paraíba (1970-1980)

This study aims to analyze the tectonic character of the works of Sergio Bernardes and Glauco Campello architects, built in Paraiba, between the turn of the decade in 1970 and early 1980 in order to bring reflections about the poetics of construction s importance in the formal structure of the architecture, contributing to the debate about the specificitiesand peculiarities of modern architecture produced in Brazil. The research, using the strategies of the case study, startsfromthe review on the use of "tectonic" by Kenneth Frampton and other scholars of the term, to base the concept and set the analytical parameters of the tectonics. Then it proceeds to the insertion of buildings in the cultural and socio-political Brazilian s context in the periodproposed forstudy, in sequence, analyzesthe works of each architect. The study confirms that the expressive power of Brazilian heroic modern architecture, emphasizing the poetics of construction, sediments a tectonic culture that resonates in the following generations

Avaliação do caráter oxidante da violaceína

Violacein is a violet pigment isolated from many gram-negative bacteria, especially from Chromobacterium violaceum, a betaproteobacterium found in the Amazon River in Brazil. It has potential medical applications as an antibacterial, fungicide, anti-tryptanocidal, anti-ulcerogenic and anti-cancer drug, among others. Furthermore, its pro-oxidant activity has been suggested, but only in two specific tumor lineages. Thus, in the present study, the prooxidant effects of violacein were investigated in both normal and tumor cells, seeking to evaluate the cell responses. The evaluation of violacein cytotoxicity using the Trypan blue dye exclusion method indicated that CHO-K1 cells were more resistant than tumor HeLa cells. The oxidative stress induced by violacein was manifested as an increase in intracellular SOD activity in CHO-K1 and MRC-5 cells at a specific concentration range. Nevertheless, a decrease was detected specifically at 6-12 μM in HeLa and MRC-5 cells. Interestingly, the increase in SOD activity was not followed by a concomitant increase in catalase activity. Regarding to oxidative stress biomarkers, increased protein carbonylation and lipid hydroperoxides levels were detected respectively in CHO-K1 and MRC-5 cells treated with violacein at 1.5-3 μM and 3 μM, which may be an evidence that this compound causes oxidative stress specifically in these conditions. Additionally, it is believed that the decline in cell viability observed in MRC-5 cells and HeLa treated with violacein at 6-12 M is due to mechanisms not related to oxidative stress. Moreover, the results suggested that violacein might cause oxidative stress by increasing endogenous levels of O2 -, since the occurrence of an expressive change in SOD activity. In addition, in order to evaluate the antioxidant activity of violacein in the absence of a biological system, the total antioxidant and iron chelating activity were evaluated, so that antioxidant activities were detected at 30 and 60 μM of violacein. Altogether, the results indicate that although oxidative stress is triggered by incubation with violacein, it did not seem to be high enough to cause serious damage to cell biomolecules in HeLa cells and only at specific concentrations in CHOK-1 and MRC-5 cells. Comparing the results obtained in cell culture and the in vitro antioxidant activity evaluation, the results confirmed that violacein presents opposing oxidant features when in presence or absence of a biological system and the antioxidant character only occurs at high concentrations of the pigment.

Bancos de sangue de cordão umbilical e placentário para uso familiar, de caráter privado, no Brasil: subsídios técnicos, legais e éticos para uma análise de implementação

Os bancos de sangue de cordão umbilical e placentário foram criados a partir da comprovação de que o sangue de cordão umbilical e placentário (SCUP) é uma fonte rica em células progenitoras hematopoéticas (CPH) e alternativa às células provenientes da medula óssea para transplante, fato que gerou o interesse pelo armazenamento das células nele contidas. A legislação brasileira distingue bancos para uso alogênico não aparentado (públicos) e para uso exclusivamente autólogo (privados). Por sua vez, o armazenamento de SCUP para uso familiar (doação dirigida) pode ser realizado em bancos de sangue de cordão umbilical e placentário públicos, serviços de hemoterapia ou centros de transplante, quando há um membro da família do nascituro com doença diagnosticada e que necessite de transplante de CPH como tratamento. Apesar de a legislação ser clara, a Anvisa tem identificado o interesse sobre a possibilidade da liberação de unidades de SCUP, armazenadas em bancos autólogos, para a utilização de outrem, familiar, além do recém-nascido beneficiário. O objetivo do trabalho visa promover a reflexão sobre uma possível modificação dos parâmetros legais nacionais que regem os bancos de SCUP autólogo, tornando-os bancos com vistas ao uso familiar, por meio da exposição dos principais elementos relacionados ao tema. O estudo analisou os critérios técnico-sanitários legais para regulamentação dos bancos; descreveu as características das CPH de diversas fontes e tipos de doação para transplante; contextualizou a relação com os princípios da Bioética; avanços sobre terapia e pesquisas relativas às CPH; e discutiu possíveis riscos envolvidos no processo.

O caráter dialógico e social do signo e do pensamento em Peirce

O caráter semiótico de todo pensamento exige que tal fenômeno seja intrinsecamente dialógico, pois uma mediação interfere na própria produção do pensamento. Todo pensamento é igualmente social, pois o signo é produto da tradição e determina um programa de conduta para o futuro que tem por sujeito último a totalidade das mentes no fim da história.

A questão da centralidade em São Paulo: o papel das associações de caráter empresarial

Dans cet article, nous envisageons traiter une série de questions concernant le contexte urbain de la ville de São Paulo. Notre objectif est d'identifier: a) comment s'organisent les principaux groupes privés en vue de situer le secteur tertiaire moderne; b) comment leur organisations font pression sur le pouvoir public afin d'obtenir des bénéfices d'infrastructure d'équipements urbains; c) quelles sont les réponses concrètes du pouvoir public; d) quels sont les principaux groupes sociaux, issus des classes populaires qui sont pourtant atteints par ce jeu d'intérêts.

Las áreas revertidas a la plena soberanía panameña por razón de los Tratados Torrijos-Carter: elementos para su planeación demográfica

Planteamiento acerca de los elementos a considerar en los planes gubernamentales, respecto a las áreas ocupadas por Estados Unidos que están reincorporándose a la soberanía panameña, teniendo en vista sus efectos demográficos.

Heroínas e Vilões: os símbolos na obra Heroes and Villains de Angela Carter

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O vôo da trapezista alada: uma leitura da trajetória de Fevvers em Noites no circo de Angela Carter

Pós-graduação em Letras - FCLAS

Valores, crenças e comportamentos nas ações e atitudes dos indivíduos de caráter ambiental no município de Lavras -MG

The concept of environment involves social, political and economic aspects, in addition to natural elements. The acknowledgement that the environmental issue is complex highlights the importance of understanding the dynamics of relations that guide the individuals in their interactions with the environment. In this sense, studies have shown the relation between values, beliefs and behaviors. The theory on values developed by Schwartz (1992) identifies the complexity of the relations between values and behavior, organizing the field of human motivation into ten motivational types. Studies conducted by Pato (2004) on environmental beliefs are capable of indicating how the individuals relate to the environment, and its predisposition in acting or not in an ecological manner, allowing an understanding of ecological behavior and its forms of manifestation. Therefore, the objective of this study consisted of analyzing the value perception over environmental beliefs and ecological behavior of the individuals inserted into the environmental theme of the municipality of Lavras, Minas Gerais, Brazil. The research was conducted using a sample of 82 participants, comprised in its majority of male (62.2%), married (54.9%) individuals, and those with age from 31 to 40 years (35.4%). A survey of four segments was conducted: Ecological Behavior Scale (EBS), Environmental Beliefs Scale (EBeS), Schwatz Value Profile (SVP-40) and sociodemographic variables. The participants assumed, first, a value orientation directed to the universalism motivational type, which involves an important set of values for understanding the behaviors in relation to the environment. Furthermore, the results showed that the behaviors related to urban cleaning and economy of water and energy are more easily assimilated, while behaviors oriented to activism/consumerism and recycling were not yet incorporated in a satisfactory manner. On the other hand, the fact of belonging to an institution of which mission is to care for the environment seems to induce the participants to show a greater predisposition to pro-environmental behaviors. The environmental issue, urgent and moved by not always confluent debates, points to the need for reorganizing daily life, which necessarily involves change in values and behaviors. Thus, this study is relevant given that the interaction between the constructs can contribute with the research and the proposition of strategies that promote a reduction of behaviors damaging to the environment, as well as the strengthening of those that contribute for its preservation, sensitizing the actors involved to reorder their roles for benefiting the environment.

Suplementação com creatina, estado redox e metabolismo glicídico muscular de ratos submetidos ao treinamento de caráter aeróbio

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Caráter Killer e antagonismo de leveduras aplicadas no biocontrole de fitopatógenos micotoxigênicos em fruta

Pós-graduação em Engenharia e Ciência de Alimentos - IBILCE

Costumbrismo, hispanismo e caráter nacional em Las mujeres españolas, portuguesas y americanas: imagens, textos e política nos anos 1870

Pós-graduação em História - FCLAS