Convenio de Colaboración entre la Universidad de Sevilla (España) y la Universidad de Cuenca (Ecuador) para cooperación en materia de Estudios de Doctorado

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El mapa colaborativo como recurso generador de autonomía de la sociedad para reducir el imaginario de determinados contextos en riesgo de exclusión social. Un estudio de caso en el Polígono Sur, Sevilla.

El siglo XXI está contribuyendo a la consolidación de un arte más social, contextual, referencial y colaborativo. El auge y la proliferación de las estrategias cartográficas son un claro ejemplo de ello, así como sus múltiples formatos de expresión. Identificar los mapas colaborativos como una herramienta capaz de comunicar lo que sucede dentro de un contexto en riesgo de exclusión social, puede ser una de las claves para que la población que en ellos habita genere conocimiento propio de sus vínculos con el territorio y así contribuya a la desmitificación de imaginarios sociales estigmáticos. Se plantea el empleo de estas estrategias en un entorno en concreto, el Polígono Sur, para valorar las consecuencias que éstas podrían tener en el fomento de una autonomía intelectual a través de una propuesta de intervención con base empírica. Ésta se ha fundamentado en los principios metodológicos de una investigación de corte cualitativo, como la investigación-acción y el estudio de caso, a la par que en las herramientas que consecuentemente se diseñaron para la obtención de información. Los resultados apuntan a que, al menos en lo que se refiere al Polígono Sur, a fin de que el mapa colaborativo se convierta en un recurso que fomente la difusión de lo que éste constituye para sus vecinos, es necesario que primeramente exista una conciencia de la situación, que promueva, a su vez, el desarrollo de un pensamiento crítico de la misma.

Enea Silvio Piccolomini en España. Con la edición del "Tratado de la miseria de los cortesanos", (Sevilla, Cromberger, 1520)

As it is well known, the Renaissance in Spain cannot be understood without a deep knowledge of the Italian quattrocento: art and thinking have an important debt with a culture that shaped a new society that can be named Modern Era. So, there are many intellectuals that are the main reference to our writers: Leonardo Bruni, Giannozzo Manetti, Bartolomeo Facio, Antonio Beccadelli, Poggio Bracciolini, Francesco Filelfo, Flavio Biondo, Lorenzo Valla, Vespasiano da Bisticci, Pier Candido Decembrio, Guarino da Verona, Pico della Mirandola, Marsilio Ficino, and a big number that includes necessarily the name of Enea Silvio Piccolomini (1405-1464). In effect, the creator that became Pope as Pío II is one outstanding figure of that Humanism that early putted down roots in Spain, a country in construction that produced very important fruits in those years. Under these circumstances, this study has as main objective to analyse the large work of the humanist Pope par excellence, and to establish the relationship between his writings and genres, works and authors in the Iberian peninsula that wrote under his influence. Furthermore, in the following pages can be found a edition of the translation, by Diego López de Cortegana, of one of Picolomini’s works, the Tratado de la miseria de los cortesanos, a work that can be taken as an example of the attention payed to his works by authors like Juan de Lucena, Rodrigo Sánchez de Arévalo, Cristóbal de Castillejo or fray Antonio de Guevara. After a brief introduction that points that the attention to Enea Silvio Piccolomini is not diminishing, that, on the contrary, is clearly alive if we consider modern editions and translations to different languages, I concentrate on the biography of Pío II. With this purpose I take as base the text that this humanist wrote with the aim of building an adequate imago vitae that related the achievements in the religious sphere (with a failed promotion of a last crusade against the Turk) and also his creative labour. I refer to the Commentarii rerum memorabilium quae temporibus suis contingerunt, an extensive autobiography that did not spare the self-praise and conceals some controversial author’s facts, such as the “reconciling” thesis that undermined the Popes authority and power. In addition, in that chapter can be found a study of the writing process of the titles that includes Piccolomini’s bibliography, since we can think that the author’s commentary is extremely relevant to inform about the moment of writing and its purpose...

Os dinheiros da Inquisição portuguesa: o exemplo dos tribunais de Évora e Lisboa (1701-1755)

A partir dos relatórios de contas, elaborados anualmente por cada Mesa da Inquisição no ato de prestar contas ao Conselho Geral do Santo Ofício, pretende-se esboçar, com este trabalho, uma análise comparativa da estrutura das receitas dos tribunais de Évora e de Lisboa. Será alvo de estudo a composição das receitas inquisitoriais afetas aos tribunais, na primeira metade do século XVIII, dando ênfase a uma questão central: em que medida o confisco de bens aos sentenciados pela Inquisição contribuía para a subsistência financeira do Santo Ofício? A historiografia tem sugerido que a Inquisição contribuía com réditos financeiros para o equilíbrio das contas públicas e ao mesmo tempo autofinanciava-se a partir daqui. Há casos pontuais em que a primeira situação se verificou, sendo que o enfoque central deste trabalho não reside aqui. Não se sabe, contudo, em que medida o confisco era importante para a vida saudável dos cofres inquisitoriais. Importará, assim, analisar a composição global das rendas afetas aos tribunais,com o objetivo de compreender qual o peso do fisco.

How did the AD 1755 tsunami impact on sand barriers across the southern coast of Portugal?

Tsunamis are highly energetic events that may destructively impact the coast. Resolving the degree of coastal resilience to tsunamis is extremely difficult and sometimes impossible. In part, our understanding is constrained by the limited number of contemporaneous examples and by the high dynamism of coastal systems. In fact, longterm changes of coastal systems can mask the evidence of past tsunamis, leaving us a short or incomplete sedimentary archive. Here, we present a multidisciplinary approach involving sedimentological, geomorphological and geophysical analyses and numerical modelling of the AD 1755 tsunami flood on a coastal segment located within the southern coast of Portugal. In particular, the work focuses on deciphering the impact of the tsunami waves over a coastal sand barrier enclosing two lowlands largely inundated by the tsunami flood. Erosional features documented by geophysical data were assigned to the AD 1755 eventwith support of sedimentological and age estimation results. Furthermore, these features allowed the calibration of the simulation settings to reconstruct the local conditions and establish the run-up range of the AD 1755 tsunami when it hit this coast (6– 8 m above mean sea level). Our work highlights the usefulness of erosional imprints preserved in the sediment record to interpret the impact of the extreme events on sand barriers

City & Spectacle: A Vision of Lisbon Before the 1755 Great Earthquake

City & Spectacle: a vision of pre-earthquake Lisbon consists of a virtual recrea on of the city of Lis- bon on the eve of the great earthquake of 1 November 1755, giving shape to a laboratory model for research into the city’s history. As its star ng point the project has the virtual recrea on of one the most emblema c of spaces from 18th century Lisbon, the Royal Opera House, which disappeared during the 1755 earthquake. The recrea on of the Opera House was developed in the scope of the commemora- ons of the 250th anniversary of the 1755 catastrophe as an a empt to restore this space of the highest ar s c quality to memory and to return it to the inventory of the Portuguese heritage of architectural history.1 Using Second Life® technology it was possible to put forward a model of both the struc- ture and interiors of the Opera House as well as its anima on combined with a small piece of the opera presented at the inaugura on of the building in April 1755. The public presenta on of this virtual model at the conference 1755: Catástrofe, memória e arte (1755: catastrophe, memory and art), which took place at the Centro de Estudos Compara- stas, Universidade de Lisboa, led to a debate on the study and cri cal analysis of documentary sources and their selec on and applica on on recrea ons using virtual world technology. It also emphasized the need to extend the research on pre-earthquake Lisbon.

Analisi dell’opera teatrale Quejío di Salvador Távora, La Cuadra de Sevilla. Il nuovo teatro contrasta la mistificazione storico-culturale dell’Andalusia

Il presente elaborato finale del corso di laurea in Mediazione Linguistica Interculturale si pone come obiettivo quello di fare luce sulla condizione che l’Andalusia versava durante gli anni che precedono e che definiscono la transizione politica degli anni 1975-1979 attraverso l’analisi dell’opera teatrale Quejío della compagnia La Cuadra de Sevilla, guidata da Salvador Távora. Dagli spettacoli di flamenco nelle storiche vie alle tradizioni centenarie e religiose che attraggono turisti da tutto il mondo, mi sono sempre chiesta se il ritratto così perfetto di questa città, e più generalmente, dell’Andalusia, rispecchiasse davvero la realtà, come quella dipinta nelle cartoline e nei quadretti che vendono ai turisti dietro Plaza de España. È proprio da qui che parte la mia analisi: ripercorrere quelle che sono le peculiarità che definiscono la regione dell’Andalusia, comprendendone limiti e manipolazioni folkloriche da parte di generazioni politiche con lo scopo di nascondere la sua vera realtà storica. A questo proposito, prenderò in analisi l’opera Quejío, come ho precedentemente detto, la quale, ricca di metafore e allusioni, rappresenta una denuncia alla povertà e repressione che dilagavano in Andalusia in quegli anni. Significativa è stata la nascita del cosiddetto Teatro Independiente, da cui La Cuadra de Sevilla ne trae gli ideali e le caratteristiche, che fa da sfondo a un periodo critico per l’Andalusia: quello della transizione spagnola, nonché il passaggio dalla dittatura di Francisco Franco alla democrazia. La regione è stata segnata negativamente dalla situazione sociale e politica: una terra rurale e di latifondisti, destinata alla precarietà e alla censura a cui La Cuadra de Sevilla si oppone contribuendo a restituire alla cultura andalusa la propria realtà storica, lontana dallo stereotipo inculcato nei viaggiatori, attraverso un grido di protesta sulle note del flamenco.

Efficacy And Safety Of Intravitreal Bevacizumab In Eyes With Neovascular Glaucoma Undergoing Ahmed Glaucoma Valve Implantation: 2-year Follow-up.

To evaluate the efficacy and safety of intravitreal bevacizumab (IVB) in eyes with neovascular glaucoma (NVG) undergoing Ahmed glaucoma valve (AGV) implantation. This was a multicentre, prospective, randomized clinical trial that enrolled 40 patients with uncontrolled neovascular glaucoma that had undergone panretinal photocoagulation and required glaucoma drainage device implantation. Patients were randomized to receive IVB (1.25 mg) or not during Ahmed valve implant surgery. Injections were administered intra-operatively, and 4 and 8 weeks after surgery. After a mean follow-up of 2.25 ± 0.67 years (range 1.5-3 years), both groups showed a significant decrease in IOP (p < 0.05). There was no difference in IOP between groups except at the 18-month interval, when IOP in IVB group was significantly lower (14.57 ± 1.72 mmHg vs. 18.37 ± 1.06 mmHg - p = 0.0002). There was no difference in survival success rates between groups. At 24 months, there was a trend to patients treated with IVB using less antiglaucoma medications than the control group (p = 0.0648). Complete regression of rubeosis iridis was significantly more frequent in the IVB group (80%) than in the control group (25%) (p = 0.0015). Intravitreal bevacizumab may lead to regression of new vessels both in the iris and in the anterior chamber angle in patients with neovascular glaucoma undergoing Ahmed glaucoma valve implantation. There is a trend to slightly lower IOPs and number of medications with IVB use during AGV implantation for neovascular glaucoma.

Contribution Of Antepartum And Intrapartum Hemorrhage To The Burden Of Maternal Near Miss And Death In A National Surveillance Study

Objective To evaluate the occurrence of severe obstetric complications associated with antepartum and intrapartum hemorrhage among women from the Brazilian Network for Surveillance of Severe Maternal Morbidity.Design Multicenter cross-sectional study.Setting Twenty-seven obstetric referral units in Brazil between July 2009 and June 2010.Population A total of 9555 women categorized as having obstetric complications.Methods The occurrence of potentially life-threatening conditions, maternal near miss and maternal deaths associated with antepartum and intrapartum hemorrhage was evaluated. Sociodemographic and obstetric characteristics and the use of criteria for management of severe bleeding were also assessed in these women.Main outcome measures The prevalence ratios with their respective 95% confidence intervals adjusted for the cluster effect of the design, and multiple logistic regression analysis were performed to identify factors independently associated with the occurrence of severe maternal outcome.Results Antepartum and intrapartum hemorrhage occurred in only 8% (767) of women experiencing any type of obstetric complication. However, it was responsible for 18.2% (140) of maternal near miss and 10% (14) of maternal death cases. On multivariate analysis, maternal age and previous cesarean section were shown to be independently associated with an increased risk of severe maternal outcome (near miss or death).Conclusion Severe maternal outcome due to antepartum and intrapartum hemorrhage was highly prevalent among Brazilian women. Certain risk factors, maternal age and previous cesarean delivery in particular, were associated with the occurrence of bleeding.

Equivalência conceitual, de itens e semântica da versão brasileira do instrumento Dysfunctional Voiding Scoring System (DVSS) para avaliação de disfunção do trato urinário inferior em crianças

Investiga-se a equivalência conceitual, de itens e semântica entre o instrumento Dysfunctional Voiding Scoring System (DVSS), utilizado para avaliar a disfunção funcional do trato urinário inferior em crianças, concebido em inglês e uma versão em português. Na primeira etapa realizou-se a avaliação da equivalência conceitual e de itens, seguida de duas traduções do instrumento original para o português. Na segunda etapa foram realizadas 63 entrevistas, com crianças de 3 a 10 anos e responsáveis, e modificação de itens segundo dificuldades de interpretação. Na terceira etapa foi realizada a retradução do instrumento em português para o inglês e avaliação da equivalência semântica. Na quarta etapa, a versão pré-teste foi aplicada em vinte duplas de crianças de 3 a 10 anos e responsáveis. Apresenta-se o instrumento em português com equivalência conceitual, de itens e semântica. Sugere-se que a aplicação do DVSS seja realizada por meio de entrevista por profissional treinado e não baseada em autopreenchimento como proposto no instrumento original.

Searching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries

Background: Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignancies in humans. The average 5-year survival rate is one of the lowest among aggressive cancers, showing no significant improvement in recent years. When detected early, HNSCC has a good prognosis, but most patients present metastatic disease at the time of diagnosis, which significantly reduces survival rate. Despite extensive research, no molecular markers are currently available for diagnostic or prognostic purposes. Methods: Aiming to identify differentially-expressed genes involved in laryngeal squamous cell carcinoma (LSCC) development and progression, we generated individual Serial Analysis of Gene Expression (SAGE) libraries from a metastatic and non-metastatic larynx carcinoma, as well as from a normal larynx mucosa sample. Approximately 54,000 unique tags were sequenced in three libraries. Results: Statistical data analysis identified a subset of 1,216 differentially expressed tags between tumor and normal libraries, and 894 differentially expressed tags between metastatic and non-metastatic carcinomas. Three genes displaying differential regulation, one down-regulated (KRT31) and two up-regulated (BST2, MFAP2), as well as one with a non-significant differential expression pattern (GNA15) in our SAGE data were selected for real-time polymerase chain reaction (PCR) in a set of HNSCC samples. Consistent with our statistical analysis, quantitative PCR confirmed the upregulation of BST2 and MFAP2 and the downregulation of KRT31 when samples of HNSCC were compared to tumor-free surgical margins. As expected, GNA15 presented a non-significant differential expression pattern when tumor samples were compared to normal tissues. Conclusion: To the best of our knowledge, this is the first study reporting SAGE data in head and neck squamous cell tumors. Statistical analysis was effective in identifying differentially expressed genes reportedly involved in cancer development. The differential expression of a subset of genes was confirmed in additional larynx carcinoma samples and in carcinomas from a distinct head and neck subsite. This result suggests the existence of potential common biomarkers for prognosis and targeted-therapy development in this heterogeneous type of tumor.