Edifícios altos – problemas associados e análise estrutural de um caso prático

Com a presente dissertação pretende-se analisar alguns dos problemas associados aos edifícios altos, na fase de projeto, bem como compilar um conjunto de informações e conhecimentos científicos sobre a área abordada. São descritas algumas soluções de sistemas estruturais possíveis de idealizar para edifícios altos. Posteriormente, tendo por base um projeto de estruturas de um edifício com 25 pisos localizado em Luanda, capital de Angola, o objetivo consistiu em analisar estática e dinamicamente o seu comportamento quando solicitado fundamentalmente pelas ações do vento e dos sismos. A análise estrutural foi realizada com recurso a dois softwares de cálculo automático, nomeadamente, o Cypecad e o Robot Structural Analysis Professional e pelos métodos preconizados no Regulamento de Segurança e Ações para estruturas de edifícios e pontes e o Eurocódigo 8 – “Projeto de estruturas para resistência aos sismos”. Aborda-se a temática do faseamento construtivo, assunto que revela algumas limitações dos programas de cálculo utilizados, sendo descrito um método simplificado para prever os seus efeitos em termos de dimensionamento final. Os resultados obtidos permitiram avaliar o bom comportamento da estrutura no que respeita ao cumprimento dos estados limites últimos e de serviço. Conclui-se que o sistema estrutural adotado no modelo em estudo se encontra bem dimensionado relativamente ao colapso e à limitação de danos.

E-sharing: development and use of learning objects repository

— In the new learning environments, built width digital technologies, the need to promote quality of education resources, commonly known as Learning Objects, which can support formal and informal distance learning, emerge as one of the biggest challenge that educational institutions will have to face. Due to the fact that is expensive, the reuse and sharing became very important issue. This article presents a Learning Object Repository which aims to store, to disseminate and maintain accessible Learning Objects.

Contributo científico e artístico do Instituto Politécnico de Lisboa para o acesso aberto: o que temos e o que queremos

Missão do Repositório Científico do IPL: divulgar a produção científica e artística da comunidade académica do Instituto Politécnico de Lisboa, aumentar a visibilidade e o impacto da investigação desenvolvida, assegurar o depósito da memória intelectual e promover o livre acesso à informação. O Repositório contém informação nas áreas da contabilidade e administração, das engenharias, da música, da dança, do teatro e cinema, das ciências da educação, das tecnologias da saúde e ainda das ciências da comunicação. O que queremos? Partilhar, melhorar e inovar a investigação científica e artística produzida pelo IPL, aprovar a política mandatória do IPL, fazer parcerias com grupos de investigação, compatibilizar com diretrizes OpenAire, dar consultoria na gestão da informação, informar sobre investigação científica e artística, promover a mobilidade de bibliotecários e avaliar as possibilidades do Repositório para estudos de caso.

Projeto e construção de subestações

Relatório de Estágio para obtenção do grau de Mestre em Engenharia Civil

O acesso à informação no quadro do funcionamento da União Europeia

O carácter federal da União Europeia pressupõe que para o seu funcionamento concorram as autoridades nacionais e subnacionais e, bem assim, todos os interessados. Estes podem beneficiar de representação institucional (tal como acontece no Comité Económico e Social), podem intervir a título de representação pontual (nomeadamente em sede de comitologia) e podem ainda participar de moro próprio, em termos agregados (lobbying) ou individuais. Toda essa intervenção pressupõe o acesso à informação, cujo regime nem sempre é compreendido. De facto, nos nossos dias, passamos rapidamente de uma sistemática falta de informação para um excesso de informação (em especial graças à internet), cujos efeitos acabam por convergir. Neste enquadramento procuramos expor, no presente trabalho, de forma estruturada, os regimes e mecanismos de acesso à informação relativa ao funcionamento da União Europeia (informação essa que é também muito útil em sede de interpretação e aplicação dos diferentes regimes jurídicos) tendo em vista apoiar todos aqueles que de uma ou outra forma, por motivos profissionais, dela têm necessidade.

O crime de fraude fiscal: o impacto na receita pública do Estado

Orientador: Doutor, José Domingos Silva Fernandes

Sistemas de avaliação de desempenho e gestão por objectivos: concepção, implementação e desenvolvimento

Trabalho de natureza profissional para a atribuição do Título de Especialista do Instituto Politécnico do Porto, na área de Recursos Humanos, defendido a 26-09-2012.

Influence of mixtures of acenaphthylene and benzo[a] anthracene on their degradation by Pleurotus ostreatus in sandy soil

Purpose Polycyclic aromatic hydrocarbons (PAHs) are a class of organic compounds commonly found as soil contaminants. Fungal degradation is considered as an environmentally friendly and cost-effective approach to remove PAHs from soil. Acenaphthylene (Ace) and Benzo[a]anthracene (BaA) are two PAHs that can coexist in soils; however, the influence of the presence of each other on their biodegradation has not been studied. The biodegradation of Ace and BaA, alone and in mixtures, by the white rot fungus Pleurotus ostreatus was studied in a sandy soil. Materials and methods Experimental microcosms containing soil spiked with different concentrations of Ace and BaAwere inoculated with P. ostreatus. Initial (t 0) and final (after 15 days of incubation) soil concentrations of Ace and BaA were determined after extraction of the PAHs. Results and discussion P. ostreatus was able to degrade 57.7% of the Ace in soil spiked at 30 mg kg−1 dry soil and 65.8% of Ace in soil spiked at 60 mg kg−1 dry soil. The degradation efficiency of BaA by P. ostreatus was 86.7 and 77.4% in soil spiked with Ace at 30 and 60 mg kg−1 dry soil, respectively. After 15 days of incubation, there were no significant differences in Ace concentration between soil spiked with Ace and soil spiked with Ace + BaA, irrespective of the initial soil concentration of both PAHs. There were also no differences in BaA concentration between soil spiked with BaA and soil spiked with BaA + Ace. Conclusions The results indicate that the fungal degradation of Ace and BaA was not influenced by the presence of each other’s PAH in sandy soil. Bioremediation of soils contaminated with Ace and BaA using P. ostreatus is a promising approach to eliminate these PAHs from the environment.

Monitorização via internet de processos industriais controlados com autómatos programáveis

Trabalho Final de Mestrado para obtenção do grau de Mestre em Engenharia Mecânica

Despacho económico de unidades com funções de custo não convexas usando enxames

Dissertação para obtenção do grau de Mestre em Engenharia Electrotécnica Ramo de Energia

Re-use assessment of thermoset composite wastes as aggregate and filler replacement for concrete-polymer composite materials: a case study regarding GFRP pultrusion wastes

Glass fibre-reinforced plastics (GFRP), nowadays commonly used in the construction, transportation and automobile sectors, have been considered inherently difficult to recycle due to both the cross-linked nature of thermoset resins, which cannot be remoulded, and the complex composition of the composite itself, which includes glass fibres, polymer matrix and different types of inorganic fillers. Hence, to date, most of the thermoset based GFRP waste is being incinerated or landfilled leading to negative environmental impacts and additional costs to producers and suppliers. With an increasing awareness of environmental matters and the subsequent desire to save resources, recycling would convert an expensive waste disposal into a profitable reusable material. In this study, the effect of the incorporation of mechanically recycled GFRP pultrusion wastes on flexural and compressive behaviour of polyester polymer mortars (PM) was assessed. For this purpose, different contents of GFRP recyclates (0%, 4%, 8% and 12%, w/w), with distinct size grades (coarse fibrous mixture and fine powdered mixture), were incorporated into polyester PM as sand aggregates and filler replacements. The effect of the incorporation of a silane coupling agent was also assessed. Experimental results revealed that GFRP waste filled polymer mortars show improved mechanical behaviour over unmodified polyester based mortars, thus indicating the feasibility of GFRP waste reuse as raw material in concrete-polymer composites.

Sustainable waste recycling solution for the glass fibre reinforced polymer composite materials industry

In this paper the adequacy and the benefit of incorporating glass fibre reinforced polymer (GFRP) waste materials into polyester based mortars, as sand aggregates and filler replacements, are assessed. Different weight contents of mechanically recycled GFRP wastes with two particle size grades are included in the formulation of new materials. In all formulations, a polyester resin matrix was modified with a silane coupling agent in order to improve binder-aggregates interfaces. The added value of the recycling solution was assessed by means of both flexural and compressive strengths of GFRP admixed mortars with regard to those of the unmodified polymer mortars. Planning of experiments and data treatment were performed by means of full factorial design and through appropriate statistical tools based on analyses of variance (ANOVA). Results show that the partial replacement of sand aggregates by either type of GFRP recyclates improves the mechanical performance of resultant polymer mortars. In the case of trial formulations modified with the coarser waste mix, the best results are achieved with 8% waste weight content, while for fine waste based polymer mortars, 4% in weight of waste content leads to the higher increases on mechanical strengths. This study clearly identifies a promising waste management solution for GFRP waste materials by developing a cost-effective end-use application for the recyclates, thus contributing to a more sustainable fibre-reinforced polymer composites industry.

Deregulated expression of selected histone methylases and demethylases in prostate carcinoma

Prostate cancer (PCa), a leading cause of cancer-related morbidity and mortality, arises through the acquisition of genetic and epigenetic alterations. Deregulation of histone methyltransferases (HMTs) or demethylases (HDMs) has been associated with PCa development and progression. However, the precise influence of altered HMTs or HDMs expression and respective histone marks in PCa onset and progression remains largely unknown. To clarify the role of HMTs and HDMs in prostate carcinogenesis, expression levels of 37 HMTs and 20 HDMs were assessed in normal prostate and PCa tissue samples by RT-qPCR. SMYD3, SUV39H2, PRMT6, KDM5A, and KDM6A were upregulated, whereas KMT2A-E (MLL1-5) and KDM4B were downregulated in PCa, compared with normal prostate tissues. Remarkably, PRMT6 was the histone modifier that best discriminated normal from tumorous tissue samples. Interestingly, EZH2 and SMYD3 expression levels significantly correlated with less differentiated and more aggressive tumors. Remarkably, SMYD3 expression levels were of independent prognostic value for the prediction of disease-specific survival of PCa patients with clinically localized disease submitted to radical prostatectomy. We concluded that expression profiling of HMTs and HDMs, especially SMYD3, might be of clinical usefulness for the assessment of PCa patients and assist in pre-therapeutic decision-making.

Enoxacin inhibits growth of prostate cancer cells and effectively restores microRNA processing

Prostate cancer (PCa) is one of the most incident malignancies worldwide. Although efficient therapy is available for early-stage PCa, treatment of advanced disease is mainly ineffective and remains a clinical challenge. microRNA (miRNA) dysregulation is associated with PCa development and progression. In fact, several studies have reported a widespread downregulation of miRNAs in PCa, which highlights the importance of studying compounds capable of restoring the global miRNA expression. The main aim of this study was to define the usefulness of enoxacin as an anti-tumoral agent in PCa, due to its ability to induce miRNA biogenesis in a TRBP-mediated manner. Using a panel of five PCa cell lines, we observed that all of them were wild type for the TARBP2 gene and expressed TRBP protein. Furthermore, primary prostate carcinomas displayed normal levels of TRBP protein. Remarkably, enoxacin was able to decrease cell viability, induce apoptosis, cause cell cycle arrest, and inhibit the invasiveness of cell lines. Enoxacin was also effective in restoring the global expression of miRNAs. This study is the first to show that PCa cells are highly responsive to the anti-tumoral effects of enoxacin. Therefore, enoxacin constitutes a promising therapeutic agent for PCa.