The sleeper effect: Artifact or phenomenon—A brief comment on Bell et al. (2013)

OBJECTIVE: Bell, Marcus, and Goodlad (2013) recently conducted a meta-analysis of randomized controlled additive trials and found that adding an additional component to an existing treatment vis-à-vis the existing treatment produced larger effect sizes on targeted outcomes at 6-months follow-up than at termination, an effect they labeled as a sleeper effect. One of the limitations with Bell et al.'s detection of the sleeper effect was that they did not conduct a statistical test of the size of the effect at follow-up versus termination. METHOD: To statistically test if the differences of effect sizes between the additive conditions and the control conditions at follow-up differed from those at termination, we used a restricted maximum-likelihood random-effect model with known variances to conduct a multilevel longitudinal meta-analysis (k = 30). RESULTS: Although the small effects at termination detected by Bell et al. were replicated (ds = 0.17-0.23), none of the analyses of growth from termination to follow-up produced statistically significant effects (ds < 0.08; p > .20), and when asymmetry was considered using trim-and-fill procedure or the studies after 2000 were analyzed, magnitude of the sleeper effect was negligible (d = 0.00). CONCLUSION: There is no empirical evidence to support the sleeper effect.

Strategies of Active Dissemination of Workplace Health Promotion

Purpose – A growing body of literature provides evidence for the efficacy of workplace health promotion (WHP). However, little is known about effective dissemination strategies for WHP interventions. The purpose of this paper is to describe how a WHP agency in Zurich, Switzerland, used bulk mailings, information events, telephone marketing and free initial consultations for the large-scale geographic marketing of WHP services, with a focus on tobacco prevention (TP). Design/methodology/approach – To analyze the number of companies responding positively to solicitation, examine the predictors of positive responses and explore the reasons for negative responses, the authors used both quantitative (e.g. a standardized questionnaire) and qualitative (telephone interviews) methods. Findings – The results show that except for telephone marketing (69 percent), the success rates of dissemination activities were very low (3-9 percent). Predictors for a positive response were institutionalization of WHP, the representative’s personal concern about TP, and problems with environmental tobacco smoke within the company. The most prominent reason for a negative Response was that the companies had already implemented TP measures by themselves and needed no further external support. Practical implications – It is suggested that TP was the wrong emphasis for a WHP program to be disseminated at that particular time, because a law on protection from passive smoking was introduced in Switzerland shortly afterwards. Originality/value – The study examines dissemination strategies under real-life Consulting conditions. It builds on on a large sample of companies and uses both quantitative and qualitative research methods. It reports specific numbers and success rates of marketing activities and thereby contributes to the knowledge about an important issue for intervention planning in the field of WHP.

Are claims made in orthodontic journal advertisements evidence-supported?

OBJECTIVE To examine the supporting evidence of advertisements published in six leading orthodontic journals. MATERIALS AND METHODS The 2012-2013 printed issues of American Journal of Orthodontics and Dentofacial Orthopedics, Australian Orthodontic Journal, Journal of Orthodontics, European Journal of Orthodontics, Journal of Clinical Orthodontics, and Journal of Orofacial Orthopedics were screened for advertisements implying superior performance compared with competitor products. Advertisements were classified according to type of product, availability, and currency of supporting references. RESULTS A total of 99 unique advertisements claiming clinical benefit or superiority were identified. The overwhelming majority of the identified advertisements promoted appliance products (62.6%), orthodontic materials (14.1%), and dental operatory equipment, including imaging systems (12.1%). Advertisements were found to provide references or not regardless of the product type. Half of the advertisements referred to at least one peer-reviewed publication, whereas unpublished studies were cited by 25% of the advertisements. Most of the referenced articles were published within the past 5 years. CONCLUSIONS The scientific background of advertisements in the orthodontic literature appears limited. While surveillance of journal advertising needs to be regulated, clinicians are urged to critically appraise the claims being made in orthodontic print advertisements by consulting the associated existing evidence.

[The overheated lunch].

We report about three patients consulting a general practitioner with acute onset of allergy-like clinical signs after having consumed tuna fish salad in the same restaurant. The treatment with antihistamines and steroids was effective and induced a quick regression of the symptoms. We look at considerations regarding the differential diagnosis and explain the pathophysiologic and the biochemical mechanisms of scombrotoxicosis.

National competence center for wildlife diseases in Switzerland: Mandate, development and current strategies.

The need for wildlife health surveillance has become increasingly recognized. However, comprehensive programs which cover a wide spectrum of species, pathogens and geographic areas are still lacking in most European countries and practical examples of systems in place remain scarce. This article provides an overview of the organization of wildlife health surveillance in Switzerland, with a focus on the development, current strategies and the activities of the national program carried out by the Centre for Fish and Wildlife Health (FIWI), University of Bern. This documentation may stimulate on-going discussions on the design and development of national wildlife health surveillance programs in other countries. Investigations into wildlife health in Switzerland date back to the 1950s. The FIWI acts as a national competence center for wildlife diseases on mandate of the Swiss federal authorities. The mandate includes four main activities: disease diagnostics, research, consulting and teaching. In line with this, the FIWI has made continuous efforts to strengthen a national network of field partners and implemented strategies to facilitate long-term and metastudies.

Adjustment Disorders Are Uniquely Suited for eHealth Interventions: Concept and Case Study

Background: Adjustment disorders (also known as mental distress in response to a stressor) are among the most frequently diagnosed mental disorders in psychiatry and clinical psychology worldwide. They are also commonly diagnosed in clients engaging in deliberate self-harm and in those consulting general practitioners. However, their reputation in research-oriented mental health remains weak since they are largely underresearched. This may change when the International Statistical Classification of Diseases-11 (ICD-11) by the World Health Organization is introduced, including a new conceptualization of adjustment disorders as a stress-response disorder with positively defined core symptoms. Objective: This paper provides an overview of evidence-based interventions for adjustment disorders. Methods: We reviewed the new ICD-11 concept of adjustment disorder and discuss the the rationale and case study of an unguided self-help protocol for burglary victims with adjustment disorder, and its possible implementation as an eHealth intervention. Results: Overall, the treatment with the self-help manual reduced symptoms of adjustment disorder, namely preoccupation and failure to adapt, as well as symptoms of depression, anxiety, and stress. Conclusions: E-mental health options are considered uniquely suited for offering early intervention after the experiences of stressful life events that potentially trigger adjustment disorders.

Evidence of hepatitis C transmission in healthcare settings in Karachi, Pakistan

Transmission of Hepatitis C (HCV) in Pakistan is a continuing public health problem. Several cultural and behavioral practices promote HCV transmission through the use of unsafe needles and blood products. This study aimed to determine the prominent risk factors associated with HCV transmission in the Indus Hospital catchment population. A case-control study design was implemented to enroll 300 laboratory confirmed HCV+ participants from consulting clinics at Indus Hospital and 300 laboratory confirmed HCV− participants from both the consulting clinics and the surrounding community. Odds ratios and their 95% were calculated for each risk factor to create a two gender specific multivariable models and a combined multivariable model. Participants who received 12 or more injections in the past year, ever received a blood transfusion, or ever had dental work performed were all independently significant more likely to be HCV+ when compared to those who received 1–4 injections in the past year, never received a blood transfusion, or never had dental work performed. Female participants who received 12 or more injections in the past year, had a blood transfusion while pregnant, or ever had dental work performed were all significantly more likely to be HCV+ while males who received 12 or more injections in the past year were also significantly more likely to be HCV+. Participants who brought their own needles to their injections or infusions along with those who were born in the Sindh province were significantly less likely to be HCV+ when compared to those who did not bring their own needles or born in the Punjab province. ^ Clearly transmission in healthcare settings are implicated for HCV transmission. A population level preventative approach must be taken to educate both the population and healthcare practitioners to prevent further transmission in the Pakistani healthcare system. Participants should also be followed and re-interviewed to ask where they received their various treatments as well as assess their knowledge and attitudes towards injections, infusions, and other unsafe medical procedures.^

Distribución de recarga virtual en Mendoza

La presente investigación se propone analizar la aparición de la recarga virtual, detallando sus ventajas y desventajas, frente a la tarjeta de recarga física, la cual a futuro reemplazará. Se realizará un análisis de cómo es la distribución de la recarga virtual en Mendoza, de donde surge, cuales son las empresas que la proveen y cómo. Para esto, en primer lugar se hará una reseña de la teoría de lo que significa la "Logística de un producto o servicio", luego se analizará cómo surge la recarga virtual en nuestro país y principalmente en nuestra provincia. Como es un proceso de recarga, quien lo realiza y cuáles son los requisitos. Se realizará un Análisis FODA del negocio, es decir que se detallarán las fortalezas y debilidades del negocio, junto a las amenazas y oportunidades que ofrece el mercado, donde actúa dicho negocio. Para esto, previamente se analizará cómo está compuesto el micro y macro entorno de la recarga virtual. Y por último se utilizará la Matriz BCG (Boston Consulting Group), para determinar qué tipo de negocio es la recarga virtual, en función de su posición en el mercado y el crecimiento del mismo. Por último, se establecerá cuáles son las próximas tendencias de la recarga virtual, es decir hacia dónde va este negocio, y cual es realmente el objetivo que desea alcanzar, para ofrecerle mayores beneficios a sus clientes, que son los usuarios de la telefonía celular.

El análisis del paisaje como herramienta y puente teórico-metodológico para la gestión socio-ambiental del territorio

El presente artículo busca comprender cómo el concepto de paisaje se transforma desde su producción y discusión académica hasta su adaptación por parte del Estado; y seguidamente, cómo este concepto termina siendo aplicado en el territorio, a través de la práctica de diversos profesionales interesados en el mismo. Para ello, se parte de algunas definiciones desarrolladas por diversas disciplinas: geografía, antropología, arqueología, ecología, agronomía y arquitectura, especificando sus puntos de interés; y se hace una comparación entre sus propuestas y la forma en la que estos conceptos son adoptados por el Estado, específicamente por medio de los denominados "términos de referencia". Posteriormente, se analiza cómo estos conceptos y metodologías son llevados a la práctica por profesionales que se desempeñan en diferentes empresas de consultoría, muchas veces sin considerar la forma en la que los habitantes locales entienden y viven el paisaje desde sus territorios. Concluyo que existe una evidente necesidad de construir puentes entre la academia, el Estado, la población y la empresa, a través de la práctica profesional y sobre la necesidad de reconocer la forma como los habitantes locales viven el concepto desde sus territorios. Solo así se logrará generar verdaderos impactos que se reflejen en una mejor calidad de vida de los habitantes

El análisis del paisaje como herramienta y puente teórico-metodológico para la gestión socio-ambiental del territorio

El presente artículo busca comprender cómo el concepto de paisaje se transforma desde su producción y discusión académica hasta su adaptación por parte del Estado; y seguidamente, cómo este concepto termina siendo aplicado en el territorio, a través de la práctica de diversos profesionales interesados en el mismo. Para ello, se parte de algunas definiciones desarrolladas por diversas disciplinas: geografía, antropología, arqueología, ecología, agronomía y arquitectura, especificando sus puntos de interés; y se hace una comparación entre sus propuestas y la forma en la que estos conceptos son adoptados por el Estado, específicamente por medio de los denominados "términos de referencia". Posteriormente, se analiza cómo estos conceptos y metodologías son llevados a la práctica por profesionales que se desempeñan en diferentes empresas de consultoría, muchas veces sin considerar la forma en la que los habitantes locales entienden y viven el paisaje desde sus territorios. Concluyo que existe una evidente necesidad de construir puentes entre la academia, el Estado, la población y la empresa, a través de la práctica profesional y sobre la necesidad de reconocer la forma como los habitantes locales viven el concepto desde sus territorios. Solo así se logrará generar verdaderos impactos que se reflejen en una mejor calidad de vida de los habitantes

El análisis del paisaje como herramienta y puente teórico-metodológico para la gestión socio-ambiental del territorio

El presente artículo busca comprender cómo el concepto de paisaje se transforma desde su producción y discusión académica hasta su adaptación por parte del Estado; y seguidamente, cómo este concepto termina siendo aplicado en el territorio, a través de la práctica de diversos profesionales interesados en el mismo. Para ello, se parte de algunas definiciones desarrolladas por diversas disciplinas: geografía, antropología, arqueología, ecología, agronomía y arquitectura, especificando sus puntos de interés; y se hace una comparación entre sus propuestas y la forma en la que estos conceptos son adoptados por el Estado, específicamente por medio de los denominados "términos de referencia". Posteriormente, se analiza cómo estos conceptos y metodologías son llevados a la práctica por profesionales que se desempeñan en diferentes empresas de consultoría, muchas veces sin considerar la forma en la que los habitantes locales entienden y viven el paisaje desde sus territorios. Concluyo que existe una evidente necesidad de construir puentes entre la academia, el Estado, la población y la empresa, a través de la práctica profesional y sobre la necesidad de reconocer la forma como los habitantes locales viven el concepto desde sus territorios. Solo así se logrará generar verdaderos impactos que se reflejen en una mejor calidad de vida de los habitantes

Time series of zooplankton abundance at station L4 in the English Channel from 1988 to 2011

Ongoing zooplankton research at the Plymouth Marine Laboratory has established a time series of zooplankton species since 1988 at L4, a coastal station off Plymouth. Samples were collected by vertical net hauls (WP2 net, mesh 200 µm; UNESCO 1968) from the sea floor (approximately 50 m) to the surface and stored in 4% formalin. Much of the zooplankton analysis has been to the level of "major taxonomic groups" only, and a number of different analysts have participated over the years. The level of expertise has generally been consistent, but the user should be aware that levels of taxonomic discrimination may vary during the course of the dataset. The dominant calanoid copepods are generally well discriminated to species throughout. Calanus has not been routinely examined for species determination, the assumption being that the local population is entirely composed of Calanus helgolandicus. In certain years there has been a particular interest in Temora stylifera, Centropages cherchiae and other species reflected in the dataset. The lack of records in other previous years does not necessarily reflect species absence. We view it as essential for all users of L4 plankton data to establish and maintain contact with the nominated current data originators as well as fully consulting the metadata. While not impinging on free data access, this ensures that this large, species-rich but slightly complex species database is being used in the correct way, and any potential issues with the data are clarified. Furthermore, a proper dialogue with these local experts on the time series will enable where appropriate the most recent sampling timepoints to be used. The data can be downloaded from BODC or from doi:10.1594/PANGAEA.778092 as files for each year by searching for "L4 zooplankton". The most comprehensive dataset is the version downloadable directly from this page. The entire set of zooplankton samples is stored at the Plymouth Marine Laboratory in buffered formalin, and may be available for further taxonomic analysis on request.

Implementación de una arquitectura de componentes para un sistema de apoyo a la toma de decisiones en Atención Primaria

Este Proyecto Fin de Grado tiene como objetivo fundamental el perfeccionamiento y puesta en explotación de un sistema de ayuda a la decisión que evalúa el desarrollo del lenguaje en niños de 0 a 6 años de edad. Este sistema está formado fundamentalmente por una aplicación diseñada y construida mediante una arquitectura de componentes de software modular y reutilizable. La aplicación será usada por los pediatras para realizar evaluaciones del desarrollo del lenguaje infantil y además por los neuropediatras, logopedas y miembros de equipos de Atención Temprana para consultar las evaluaciones y validar las decisiones propuestas por el sistema. El sistema es accesible vía web y almacena toda la información que maneja en una base de datos. Asimismo, el sistema se apoya en un modelo conceptual u ontología desarrollado previamente para inferir las decisiones adecuadas para las evaluaciones del lenguaje. El sistema incorpora las funciones de gestión de los usuarios del mismo. ABSTRACT This Grade End Project has as fundamental objective the improvement and deployment of a decision support system for evaluating children language development from 0 to 6 years of age. This system is mainly formed by an application designed and built using a modular and reusable software component architecture. The application will be used by pediatricians for evaluating children´s speech development and also by neuro-pediatricians, speech therapists and early childhood intervention team members, for consulting previous evaluations and for validating system´s proposed decision. The system is web based and stores its information in a database. Likewise, the system is supported by a conceptual model or ontology previously developed to infer the appropriate decision for language evaluation. The system also includes user management functions.

Med Capital Partners: plan de negocio de una EAFI

Med Capital Partners (MCP en adelante) es un empresa de asesoramiento financiero independiente (EAFI) que ofrecerá servicios de asesoramiento personalizado tanto a clientes particulares como a empresas, complementando su oferta con otros servicios auxiliares, que le permitan brindar a sus clientes una solución integral. MCP ha sido fundada por tres socios con formación y experiencia específica en el ámbito objeto del negocio, pero multidisciplinar para ofrecer un amplio espectro de servicios de calidad tanto en la Región de Murcia, donde va a establecer su sede, como en el resto de territorio nacional. MCP se crea con la firme misión de ofrecer servicios de asesoramiento y consulta financieros para la gestión y planificación patrimonial de calidad, de forma independiente y transparente y con la motivación de ser el médico de cabecera financiero de familias, particulares y empresas de todos los ámbitos, basándonos en arraigados valores entre los que predominan la transparencia, la independencia y la discreción. Una vez analizados los factores externos y haber realizado los planes de marketing, operaciones y financiero, nos encontramos en disposición de determinar que: 1.Existe un gran número de clientes potenciales. 2.Los factores político, social y legal favorecen la creación de este tipo de empresas. 3.Hay pocos competidores establecidos hasta la fecha. 4.No necesita complicadas infraestructuras ni requiere elevados gastos de aprovisionamiento. 5.Desde el año 2, se obtienen resultados positivos. La propuesta de valor de MCP está focalizada en ofrecer un servicio de calidad al menor precio posible, fijando una política de tarifas inferior a la media nacional y a la de nuestros competidores más cercanos, así como un esquema de precios descendentes para aquellos clientes que depositen su confianza en nosotros y renueven su contrato de asesoramiento continuado o contraten un combo de servicios. En términos operativos, el establecimiento de MCP requiere relativamente poco capital inicial, permitiendo ofrecer los primeros dividendos a los socios en un corto espacio temporal y teniendo desde el primer momento, un sueldo que les permita dedicarse plenamente al funcionamiento de MCP. En definitiva, creemos que MCP puede dar respuesta a una gran oportunidad de negocio existente en un sector en alza y en un mercado de arranque en el que hay una gran riqueza y poca cultura de inversión asesorada. ---ABSTRACT---Med Capital Partners (MCP) is an invest services company, which is established according to an EAFI structure. MCP will offer a custom-made service not only to individual clients but also to enterprises, with a wide range of supplementary services, including industrial strategy projects and all kind of financial processes demanded. MCP has been founded by three partners with proved training and specific experience based on the financial field but multitask and different between them, in order to offer various quality services in Región de Murcia, where it is going to be based, and also all around Spain. MCP is built with the firm mission of offering assessment and financial consulting quality services, helping with the patrimonial management and planning, doing it in an independent and transparent way, and always driving by the motivation of being the family doctor of individual and enterprise of sectors. To make it possible, MCP has deep values as excellence, wisdom and discretion. Once we have analyzed external factors and having made marketing, operations and financial plans, we are ready to determinate: 1.There is a big amount of potential customers. 2.Political, social and legal factors favor the formation of this type of business. 3.There are not many established competitors until now. 4.MCP does not need complex infrastructures either raised initial investment. 5.From year 2 and on, MCP is profitable. The value proposition of MCP is to focus on developing quality services with affordable fees, fixing a price policy under any other Spanish EAFI. MCP wants to build processes according to reality, working with reachable expectations and on real times. MCP is committed to the creation of stable, sustainable and consistent structures to adapt themselves to the individual risk profile of the customers, taking care of all of them. MCP wants to build a close relationship with clients and has developed a descending fee policy. MCP establishment does not require high initial resources and it is profitable in a short time, allowing investors to get their first dividends. Summarizing, we can say MCP is the answer of a big business opportunity within a rising and wealth market that only need a little help to emerge.