Copying, emergence, and digital reproduction

This talk combines concepts of the copying of manuscripts in the age before mechanical reproduction (as described in W. Benjamin’s famous Artwork-essay), of the emergence of non-vertical evolution (as to be found in textual ‘contamination’ and in horizontal gene transfer alike), and of the electronic reproduction of such phenomena (as presented in scholarly digital editions and phylogenetic trees). The guiding idea is that ‘copying’, ‘emergence’, and ‘(digital) reproduction’ enable variation depending on particular physical or biological forms, on contextual or environmental conditions, as well as on user habits or receptive fields. – Is it possible to develop a theory of copying and reproduction on this base? The material of the talk will be drawn from the Parzival-Project, a critical electronic edition of an Arthurian romance, composed by the German poet Wolfram von Eschenbach shortly after 1200 and transmitted in over eighty witnesses.

Stuck in Mobility? Fragmented Journeys of Migrants without Chances of Admission in Europe

This paper is about young migrants without chance of being granted legal residence status in the Schengen zone. Previous observations suggest that some migrants, whose country of origin leaves them with low chances of receiving asylum or in fact any type of residence permit, exhibit a highly complex migration pattern that is characterised by 1) durable “transit” across Europe, which is a multi-linear movement according to opportunities that open up along the journey; 2) a high degree of flexibility, as they have to respond to suddenly changing conditions, such as work opportunities, rejection of asylum claims, detention or deportation, and 3) switching between different legal statuses, such as asylum seeker, sans papiers or detainee. The experiences of these young adults thus show a deep ambivalence between a sense of autonomy, on the one hand, and of profound hope and powerlessness, on the other. The Dublin Convention intends to limit such a hypermobility of migrants but seems to fail in many cases. Simultaneously it provokes some of the movements by sending asylum seekers and irregular migrants back to their first country of arrivals. Given the fact that little is known about these fragmented journeys inside of the Schengen area, this ethnographic study produces novel data on a highly pertinent migration pattern, the impact of the European migration management on individual migrants as well as the inter-relatedness of the asylum regime and irregular migration in Europe. At the same time these fragmented journeys are an excellent example to discuss mobility as a resource on the one hand (since it enables this specific migrant group to extend their presence in Europe) and as a handicap on the other (since it impedes the building of stable social networks, the planning of the future, etc.).

DIRECT EFFECT OF MELATONIN UPON THE RELEASE OF GONADOTROPINS FROM THE SUPERFUSED PITUITARY GLAND OF THE MALE GOLDEN HAMSTER

The pineal gland is known to be light sensitive and to be involved in the seasonal reproduction of male golden hamster Mesocricetus auratus. In general, the pineal gland has been demonstrated to be inhibitory to the reproductive system of the male golden hamster. Melatonin is a pineal hormone which can mimic the action of the pineal gland upon the reproductive system. However, the actual site(s) of melatonin action in the hamster has not been demonstrated. In this study a direct effect of melatonin on the release of FSH and LH from superfused hamster pituitary glands was investigated.^ The superfused pituitary glands showed a stable in vitro basal release of FSH and LH for up to 10 hours. The superfused pituitaries demonstrated reproducible responses to repeated pulses of 10('-8) M LHRH, and a dose-dependent response to stimulation with different concentrations of LHRH.^ Melatonin inhibited the basal release of FSH and LH from superfused hamster pituitary glands. This effect of melatonin was specific and not a general indolamine or catecholamine effect.^ The superfused pituitaries had a diurnal differential responsiveness to physiological concentrations of melatonin with respect to FSH and LH release which were related to the light cycle used to maintain the experimental animals. A LD 14:10 photoperiod cycle was used with light on from 5 a.m. till 7 p.m.. With pituitary glands obtained at 8:30 a.m., the basal release of FSH exhibited an initial inhibition, a gradual rebound at approximately two hours after the beginning of melatonin superfusion, and a significant overshoot of FSH release after the cessation of infusion with melatonin (Morning Response). If the pituitary glands were obtained from hamsters which were sacrificed at 3:30 p.m., the release rate of FSH exhibited an inhibition during the entire period of melatonin infusion with a rebound effect appearing only after melatonin infusion was discontinued (Afternoon Response). There was no significant difference in the responsiveness of the pituitary gland to infusion with melatonin at either 8:30 a.m. or 3:30 p.m. with respect to LH release. Also, melatonin could not inhibit the gonadotropins response to continuous superfusion with 10('-9) M LHRH in pituitaries obtained at either 8:30 a.m. or 3:30 p.m., nor inhibit the stimulatory effect of pulsatile 10('-9) M LHRH. . . . (Author's abstract exceeds stipulated maximum length. Discontinued here with permission of author.) UMI^

Cost-effectiveness analysis of a 2-stage community-based hepatocellular carcinoma screening program in Taiwan

Hepatocellular carcinoma (HCC) has been ranked as the top cause of death due to neoplasm malignancy in Taiwan for years. The high incidence of HCC in Taiwan is primarily attributed to high prevalence of hepatitis viral infection. Screening the subjects with liver cirrhosis for HCC was widely recommended by many previous studies. The latest practice guideline for management of HCC released by the American Association for the Study of Liver Disease (AASLD) in 2005 recommended that the high risk groups, including cirrhotic patients, chronic HBV/HCV carriers, and subjects with family history of HCC and etc., should undergo surveillance.^ This study aims to investigate (1) whether the HCC screening program can prolong survival period of the high risk group, (2) what is the incremental cost-effectiveness ratio of the HCC screening program in Taiwan, as compared with a non-screening strategy from the payer perspective, (3) which high risk group has the lowest ICER for the HCC screening program from the insurer's perspective, in comparison with no screening strategy of each group, and (4) the estimated total cost of providing the HCC screening program to all high risk groups.^ The high risk subjects in the study were identified from the communities with high prevalence of hepatitis viral infection and classified into three groups (cirrhosis group, early cirrhosis group, and no cirrhosis group) at different levels of risk to HCC by status of liver disease at the time of enrollment. The repeated ultrasound screenings at an interval of 3, 6, and 12 months were applied to cirrhosis group, early cirrhosis group, and no cirrhosis group, respectively. The Markov-based decision model was constructed to simulate progression of HCC and to estimate the ICER for each group of subjects.^ The screening group had longer survival in the statistical results and the model outcomes. Owing to the low HCC incidence rate in the community-based screening program, screening services only have limited effect on survival of the screening group. The incremental cost-effectiveness ratio of the HCC screening program was $3834 per year of life saved, in comparison with the non-screening strategy. The estimated total cost of each group from the screening model over 13.5 years approximately consumes 0.13%, 1.06%, and 0.71% of total amount of adjusted National Health Expenditure from Jan 1992 to Jun 2005. ^ The subjects at high risk of developing HCC to undergo repeated ultrasound screenings had longer survival than those without screening, but screening was not the only factor to cause longer survival in the screening group. The incremental cost-effectiveness ratio of the 2-stage community-based HCC screening program in Taiwan was small. The HCC screening program was worthy of investment in Taiwan. In comparison with early cirrhosis group and no cirrhosis group, cirrhosis group has the lowest ICER when the screening period is less than 19 years. The estimated total cost of providing the HCC screening program to all high risk groups consumes approximately 1.90% of total amount of adjusted 13.5-year NHE in Taiwan.^

Anatomia in qua tota humani corporis fabrica... Amstelodami, Ioannes Ianssonius, 1617

A paper affixed to the rear free endpaper of the item states that is edition contains “fine reproductions of the Gemini plates.” “Thomas Geminus was a a pseudonym for Thomas Lambrit, an engraver and printer…shown as active from about 1540; he died in May 1562.” http://www.arsanatomica.lib.ed.ac.uk/geminus.html accessed 11/20/2012. Geminus (Lambrit) printed Compendiosa totius anatomiae delineation aere exarata in 1545 copied from Vesalius’ 1543, De humani corporis fabrica . (Wellcome Library catalog, accessed 11/20/2012.) This book is a 1617 reproduction of the engraved copperplates which Lambrit himself copied from the original woodblock prints of the Vesalius’ book. Because the illustrations were based on those in the Vesalius’ book, because the name Vesalius helped sell the book, because copyright laws were not in effect, and because photocopies and digital images were not available, the author of this book is given as Andreas Vesalius. (Vesalius may or may not have been pleased.) For more information on Thomas Geminus (Lambrit) see The Anatomy of Thomas Geminus, by Geoffrey Keynes, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413790/?page=1

Intersecciones : Política social e inserción laboral : Un estudio de caso sobre la informalidad de subsistencia en un barrio del Conurbano Bonaerense

La política social y el mercado de trabajo son dimensiones del sistema social mutuamente implicadas en las sociedades industriales capitalistas. Sin embargo, una interpretación apresurada sobre el mundo social podría opacar los procesos que hacen que en un grupo de la población se yuxtapongan: una inserción laboral precaria dentro del mercado de trabajo informal junto con la (re) construcción de ese grupo como sujeto-objeto de políticas sociales. El artículo tiene por propósito problematizar las representaciones dominantes sobre el trabajo y su relación con las prácticas de organización de los hogares, considerando que en su interior la dimensión laboral se articula con otros recursos (provenientes de las políticas sociales). De modo más específico, el objetivo se orienta a la descripción y análisis de prácticas y representaciones sobre la situaci162n ocupacional de jefas/es y cónyuges que realizan actividades laborales en la informalidad de subsistencia. Se plantea como hipótesis exploratoria que en el período actual las condiciones de trabajo y representaciones de los trabajadores ocupados en ese tipo de actividades expresarían la existencia de un tipo de informalidad fuertemente segregada respecto de las actividades productivas, un en un contexto de crecimiento del empleo. También se sostiene que las formas bajo las cuales estas inserciones laborales se articulan con los planes sociales (como un nivel específico de política social) evidenciarían el carácter de la contribución estatal a la reproducción de las condiciones de vida de los trabajadores insertos en este tipo de informalidad. Los hallazgos presentados constituyen un avance de investigación sobre la reproducción de la marginalidad urbana en el Conurbano Bonaerense. Parte del trabajo de campo se realizó durante el año 2008, en un barrio del Partido de Almirante Brown. Se organizaron dos grupos de discusión: uno con mujeres perceptoras de planes y otro con hombres que realizaban changas como actividad principal. Con el objeto de aportar datos acerca de las condiciones materiales de los hogares, se aplicó un cuestionario a los participantes. Junto con esta información, se analizaron registros de campo tomados en observaciones realizadas en diversos espacios del barrio

Intersecciones : Política social e inserción laboral : Un estudio de caso sobre la informalidad de subsistencia en un barrio del Conurbano Bonaerense

La política social y el mercado de trabajo son dimensiones del sistema social mutuamente implicadas en las sociedades industriales capitalistas. Sin embargo, una interpretación apresurada sobre el mundo social podría opacar los procesos que hacen que en un grupo de la población se yuxtapongan: una inserción laboral precaria dentro del mercado de trabajo informal junto con la (re) construcción de ese grupo como sujeto-objeto de políticas sociales. El artículo tiene por propósito problematizar las representaciones dominantes sobre el trabajo y su relación con las prácticas de organización de los hogares, considerando que en su interior la dimensión laboral se articula con otros recursos (provenientes de las políticas sociales). De modo más específico, el objetivo se orienta a la descripción y análisis de prácticas y representaciones sobre la situaci162n ocupacional de jefas/es y cónyuges que realizan actividades laborales en la informalidad de subsistencia. Se plantea como hipótesis exploratoria que en el período actual las condiciones de trabajo y representaciones de los trabajadores ocupados en ese tipo de actividades expresarían la existencia de un tipo de informalidad fuertemente segregada respecto de las actividades productivas, un en un contexto de crecimiento del empleo. También se sostiene que las formas bajo las cuales estas inserciones laborales se articulan con los planes sociales (como un nivel específico de política social) evidenciarían el carácter de la contribución estatal a la reproducción de las condiciones de vida de los trabajadores insertos en este tipo de informalidad. Los hallazgos presentados constituyen un avance de investigación sobre la reproducción de la marginalidad urbana en el Conurbano Bonaerense. Parte del trabajo de campo se realizó durante el año 2008, en un barrio del Partido de Almirante Brown. Se organizaron dos grupos de discusión: uno con mujeres perceptoras de planes y otro con hombres que realizaban changas como actividad principal. Con el objeto de aportar datos acerca de las condiciones materiales de los hogares, se aplicó un cuestionario a los participantes. Junto con esta información, se analizaron registros de campo tomados en observaciones realizadas en diversos espacios del barrio

Intersecciones : Política social e inserción laboral : Un estudio de caso sobre la informalidad de subsistencia en un barrio del Conurbano Bonaerense

La política social y el mercado de trabajo son dimensiones del sistema social mutuamente implicadas en las sociedades industriales capitalistas. Sin embargo, una interpretación apresurada sobre el mundo social podría opacar los procesos que hacen que en un grupo de la población se yuxtapongan: una inserción laboral precaria dentro del mercado de trabajo informal junto con la (re) construcción de ese grupo como sujeto-objeto de políticas sociales. El artículo tiene por propósito problematizar las representaciones dominantes sobre el trabajo y su relación con las prácticas de organización de los hogares, considerando que en su interior la dimensión laboral se articula con otros recursos (provenientes de las políticas sociales). De modo más específico, el objetivo se orienta a la descripción y análisis de prácticas y representaciones sobre la situaci162n ocupacional de jefas/es y cónyuges que realizan actividades laborales en la informalidad de subsistencia. Se plantea como hipótesis exploratoria que en el período actual las condiciones de trabajo y representaciones de los trabajadores ocupados en ese tipo de actividades expresarían la existencia de un tipo de informalidad fuertemente segregada respecto de las actividades productivas, un en un contexto de crecimiento del empleo. También se sostiene que las formas bajo las cuales estas inserciones laborales se articulan con los planes sociales (como un nivel específico de política social) evidenciarían el carácter de la contribución estatal a la reproducción de las condiciones de vida de los trabajadores insertos en este tipo de informalidad. Los hallazgos presentados constituyen un avance de investigación sobre la reproducción de la marginalidad urbana en el Conurbano Bonaerense. Parte del trabajo de campo se realizó durante el año 2008, en un barrio del Partido de Almirante Brown. Se organizaron dos grupos de discusión: uno con mujeres perceptoras de planes y otro con hombres que realizaban changas como actividad principal. Con el objeto de aportar datos acerca de las condiciones materiales de los hogares, se aplicó un cuestionario a los participantes. Junto con esta información, se analizaron registros de campo tomados en observaciones realizadas en diversos espacios del barrio

Composition of sediments, rocks, and ores from the Northern and Equatorial Indian Ocean

The monograph has been written on the base of data obtained from samples and materials collected during the 19-th cruise of RV ''Akademik Vernadsky'' to the Northern and Equatorial Indian Ocean. Geological features of the region (stratigraphy, tectonic structure, lithology, distribution of ore-forming components in bottom sediments, petrography of igneous rocks, etc.) are under consideration. Regularities of trace element concentration in Fe-Mn nodules, nodule distribution in bottom sediments, and engineering-geological properties of sediments within the nodule fields have been studied. Much attention is paid to ocean crust rocks. The wide range of ore mineralization (magnetite, chromite, chalcopyrite, pyrite, pentlandite, and other minerals) has been ascertained.

Conservation Projects (ConPro) data base from The Nature Conservancy and others about the protected areas with analyzed Conservation Action Plans (CAP) before 2009 (Appendix 1) and after 2009 (Appendix 2)

It is widely recognized that climate change poses significant challenges to the conservation of biodiversity. The need of dealing with relatively rapid and uncertain environmental change calls for the enhancement of adaptive capacity of both biodiversity and conservation management systems. Under the hypothesis that most of the conventional biodiversity conservation tools do not sufficiently stimulate a dynamic protected area management, which takes rapid environmental change into account, we evaluated almost 900 of The Nature Conservancy's site-based conservation action plans. These were elaborated before a so-called climate clinic in 2009, an intensive revision of existing plans and a climate change training of the planning teams. We also compare these results with plans elaborated after the climate clinic. Before 2009, 20% of the CAPs employed the term "climate change" in their description of the site viability, and 45% identified key ecological attributes that are related to climate. 8% of the conservation strategies were directly or indirectly related to climate change adaptation. After 2009, a significantly higher percentage of plans took climate change into account. Our data show that many planning teams face difficulties in integrating climate change in their management and planning. However, technical guidance and concrete training can facilitate management teams learning processes. Arising new tools of adaptive conservation management that explicitly incorporate options for handling future scenarios, vulnerability analyses and risk management into the management process have the potential of further making protected area management more proactive and robust against change.

Carbohydrates in particulate matter of the Northwest Pacific

Patterns of distribution and variations of group and monosaccharide compositions of carbohydrates in suspended matter of the Pacific Ocean were studied. It is shown that carbohydrate content of surface ocean waters depends on reproduction of organic matter by phytoplankton. Water-insoluble polysaccharides (average 77.9% of total) predominate in composition of carbohydrates in suspended matter. Water-soluble polysaccharides and oligosaccharides were detected in considerably smaller quantities (average 12.4 and 7.3% respectively). Free monosaccharides were not detected. The main sugars in all isolated groups of carbohydrates of suspended matter are hexoses, which account for 90.8% in oligosaccharides, 64.9% in water-soluble polysaccharides, and 69.8% in water-insoluble polysaccharides. Determination of monosaccharide composition of carbohydrates in suspension showed that apparently they basically consist of mixture of reserve and structural polysaccharides (or their residues) of phytoplankton organisms.